Oxodipine (BioDeep_00000756747)
代谢物信息卡片
化学式: C19H21NO6 (359.13688060000004)
中文名称: 奥索地平
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC(=O)C1=C(NC(=C(C1C2=C3C(=CC=C2)OCO3)C(=O)OC)C)C
InChI: InChI=1S/C19H21NO6/c1-5-24-19(22)15-11(3)20-10(2)14(18(21)23-4)16(15)12-7-6-8-13-17(12)26-9-25-13/h6-8,16,20H,5,9H2,1-4H3
描述信息
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers
D000077264 - Calcium-Regulating Hormones and Agents
D049990 - Membrane Transport Modulators
C93038 - Cation Channel Blocker
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Naguib Salleh, Vivi Noryati Ahmad. In-VITRo effect of Ficus deltoidea on the contraction of isolated rat's uteri is mediated via multiple receptors binding and is dependent on extracellular calcium.
BMC complementary and alternative medicine.
2013 Dec; 13(?):359. doi:
10.1186/1472-6882-13-359. [PMID: 24330515] - Catherine Le Blanc, Chantal Mironneau, Caroline Barbot, Morgana Henaff, Tzvetanka Bondeva, Reinhard Wetzker, Nathalie Macrez. Regulation of vascular L-type Ca2+ channels by phosphatidylinositol 3,4,5-trisphosphate.
Circulation research.
2004 Aug; 95(3):300-7. doi:
10.1161/01.res.0000138017.76125.8b. [PMID: 15242973] - D Dayan, A Kozlovsky, H Tal, N Kariv, M Shemesh, A Nyska. Castration prevents calcium channel blocker-induced gingival hyperplasia in beagle dogs.
Human & experimental toxicology.
1998 Jul; 17(7):396-402. doi:
10.1177/096032719801700706. [PMID: 9726536] - V Chapeau, A Moulin, M Caude, A Dufour. High-performance liquid chromatographic determination of oxodipine enantiomers, a new 1,4-dihydropyridine, applied to stereoselectivity studies in man and dog.
Journal of chromatography. B, Biomedical applications.
1994 Oct; 660(2):341-6. doi:
10.1016/0378-4347(94)00288-6. [PMID: 7866524] - A Nyska, T Waner, S Shapira, E Skutelski, A Galiano, D Dayan. Thickening of the adrenal zona glomerulosa in dogs induced by oxodipine, a calcium channel blocker.
Toxicologic pathology.
1992; 20(4):549-55. doi:
10.1177/019262339202000401. [PMID: 1308622] - F Egros, O Lhot, M Stypulkowski, T Hulot, A Dufour. An original intragastric delivery system for oral administration of solid formulations to fully conscious rats: its application to oxodipine studies.
European journal of drug metabolism and pharmacokinetics.
1991; Spec No 3(?):71-6. doi:
NULL. [PMID: 1820939] - T Waner, A Nyska, E Bogin, R Levy, A Galiano. Drug-induced decrease of serum alanine and aspartate aminotransferase activity in the rat, as a result of treatment with oxodipine, a new calcium channel blocker.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie.
1990 Jan; 28(1):25-30. doi:
NULL. [PMID: 2313233]