8-Nitroguanine (BioDeep_00000756210)
代谢物信息卡片
8-Nitroguanine
化学式: C5H4N6O3 (196.03448740000002)
中文名称: 8-硝基鸟嘌呤
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C12=C(N=C(NC1=O)N)N=C(N2)[N+](=O)[O-]
InChI: InChI=1S/C5H4N6O3/c6-4-8-2-1(3(12)10-4)7-5(9-2)11(13)14/h(H4,6,7,8,9,10,12)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Raluca-Ioana Stefan-van Staden, Liliana-Roxana Balahura, Catalina Cioates-Negut, Hassan Y Aboul-Enein. Stochastic microsensors for the assessment of DNA damage in cancer.
Analytical biochemistry.
2020 09; 605(?):113839. doi:
10.1016/j.ab.2020.113839. [PMID: 32702437] - Natalie Sims, Jack Rice, Barbara Kasprzyk-Hordern. An ultra-high-performance liquid chromatography tandem mass spectrometry method for oxidative stress biomarker analysis in wastewater.
Analytical and bioanalytical chemistry.
2019 Apr; 411(11):2261-2271. doi:
10.1007/s00216-019-01667-8. [PMID: 30796487] - Chiung-Wen Hu, Yuan-Jhe Chang, Jian-Lian Chen, Yu-Wen Hsu, Mu-Rong Chao. Sensitive Detection of 8-Nitroguanine in DNA by Chemical Derivatization Coupled with Online Solid-Phase Extraction LC-MS/MS.
Molecules (Basel, Switzerland).
2018 Mar; 23(3):. doi:
10.3390/molecules23030605. [PMID: 29517997] - Preeyaphan Phookphan, Panida Navasumrit, Somchamai Waraprasit, Jeerawan Promvijit, Krittinee Chaisatra, Thitirat Ngaotepprutaram, Mathuros Ruchirawat. Hypomethylation of inflammatory genes (COX2, EGR1, and SOCS3) and increased urinary 8-nitroguanine in arsenic-exposed newborns and children.
Toxicology and applied pharmacology.
2017 02; 316(?):36-47. doi:
10.1016/j.taap.2016.12.015. [PMID: 28025110] - Pei-Wei Wang, Mei-Lien Chen, Li-Wei Huang, Winnie Yang, Kuen-Yuh Wu, Yu-Fang Huang. Prenatal nonylphenol exposure, oxidative and nitrative stress, and birth outcomes: A cohort study in Taiwan.
Environmental pollution (Barking, Essex : 1987).
2015 Dec; 207(?):145-51. doi:
10.1016/j.envpol.2015.08.044. [PMID: 26367708] - Hung-Ju Lin, Shu-Ting Chen, Hon-Yen Wu, Hsiu-Ching Hsu, Ming-Fong Chen, Yuan-Teh Lee, Kuen-Yuh Wu, Kuo-Liong Chien. Urinary biomarkers of oxidative and nitrosative stress and the risk for incident stroke: a nested case-control study from a community-based cohort.
International journal of cardiology.
2015 Mar; 183(?):214-20. doi:
10.1016/j.ijcard.2015.01.043. [PMID: 25675904] - D Villaño, C Vilaplana, S Medina, R Cejuela-Anta, J M Martínez-Sanz, P Gil, H-G Genieser, F Ferreres, A Gil-Izquierdo. Effect of elite physical exercise by triathletes on seven catabolites of DNA oxidation.
Free radical research.
2015; 49(8):973-83. doi:
10.3109/10715762.2015.1025388. [PMID: 25786325] - Pei-Wei Wang, Mei-Lien Chen, Li-Wei Huang, Winnie Yang, Kuen-Yuh Wu, Yu-Fang Huang. Nonylphenol exposure is associated with oxidative and nitrative stress in pregnant women.
Free radical research.
2015; 49(12):1469-78. doi:
10.3109/10715762.2015.1088644. [PMID: 26514441] - Jeffrey C Wigle, Eric A Holwitt, Larry E Estlack, Gary D Noojin, Katharine E Saunders, Valdislav V Yakovlev, Benjamin A Rockwell. No effect of femtosecond laser pulses on M13, E. coli, DNA, or protein.
Journal of biomedical optics.
2014 Jan; 19(1):15008. doi:
10.1117/1.jbo.19.1.015008. [PMID: 24474502] - Meng-Jie Li, Jun-Bo Zhang, Wen-Li Li, Qing-Cui Chu, Jian-Nong Ye. Capillary electrophoretic determination of DNA damage markers: content of 8-hydroxy-2'-deoxyguanosine and 8-nitroguanine in urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Dec; 879(32):3818-22. doi:
10.1016/j.jchromb.2011.10.026. [PMID: 22098717] - Yuan-Jiao Huang, Bei-Bei Zhang, Ning Ma, Mariko Murata, An-Zhou Tang, Guang-Wu Huang. Nitrative and oxidative DNA damage as potential survival biomarkers for nasopharyngeal carcinoma.
Medical oncology (Northwood, London, England).
2011 Mar; 28(1):377-84. doi:
10.1007/s12032-010-9434-2. [PMID: 20339958] - M Marin-Kuan, V Ehrlich, T Delatour, C Cavin, B Schilter. Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a.
Journal of toxicology.
2011; 2011(?):645361. doi:
10.1155/2011/645361. [PMID: 21776264] - Simon Wan Chan, Peter C Dedon. The biological and metabolic fates of endogenous DNA damage products.
Journal of nucleic acids.
2010 Dec; 2010(?):929047. doi:
10.4061/2010/929047. [PMID: 21209721] - Suksanti Prakobwong, Puangrat Yongvanit, Yusuke Hiraku, Chawalit Pairojkul, Paiboon Sithithaworn, Porntip Pinlaor, Somchai Pinlaor. Involvement of MMP-9 in peribiliary fibrosis and cholangiocarcinogenesis via Rac1-dependent DNA damage in a hamster model.
International journal of cancer.
2010 Dec; 127(11):2576-87. doi:
10.1002/ijc.25266. [PMID: 20162672] - Umawadee Laothong, Porntip Pinlaor, Yusuke Hiraku, Patcharee Boonsiri, Suksanti Prakobwong, Jarinya Khoontawad, Somchai Pinlaor. Protective effect of melatonin against Opisthorchis viverrini-induced oxidative and nitrosative DNA damage and liver injury in hamsters.
Journal of pineal research.
2010 Oct; 49(3):271-82. doi:
10.1111/j.1600-079x.2010.00792.x. [PMID: 20626588] - Ning Ma, Mikio Sasoh, Shosuke Kawanishi, Hiromichi Sugiura, Fengyuan Piao. Protection effect of taurine on nitrosative stress in the mice brain with chronic exposure to arsenic.
Journal of biomedical science.
2010 Aug; 17 Suppl 1(?):S7. doi:
10.1186/1423-0127-17-s1-s7. [PMID: 20804627] - Somchai Pinlaor, Puangrat Yongvanit, Suksanti Prakobwong, Butsara Kaewsamut, Jarinya Khoontawad, Porntip Pinlaor, Yusuke Hiraku. Curcumin reduces oxidative and nitrative DNA damage through balancing of oxidant-antioxidant status in hamsters infected with Opisthorchis viverrini.
Molecular nutrition & food research.
2009 Oct; 53(10):1316-28. doi:
10.1002/mnfr.200800567. [PMID: 19753608] - Christophe Cavin, Thierry Delatour, Maricel Marin-Kuan, François Fenaille, Daisy Holzhäuser, Gabrièla Guignard, Claudine Bezençon, Dominique Piguet, Véronique Parisod, Janique Richoz-Payot, Benoît Schilter. Ochratoxin A-mediated DNA and protein damage: roles of nitrosative and oxidative stresses.
Toxicological sciences : an official journal of the Society of Toxicology.
2009 Jul; 110(1):84-94. doi:
10.1093/toxsci/kfp090. [PMID: 19414514] - Somchai Pinlaor, Yusuke Hiraku, Puangrat Yongvanit, Saeko Tada-Oikawa, Ning Ma, Porntip Pinlaor, Paiboon Sithithaworn, Banchob Sripa, Mariko Murata, Shinji Oikawa, Shosuke Kawanishi. iNOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel.
International journal of cancer.
2006 Sep; 119(5):1067-72. doi:
10.1002/ijc.21893. [PMID: 16570287] - Tomohiro Sawa, Masayuki Tatemichi, Takaaki Akaike, Alain Barbin, Hiroshi Ohshima. Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography-electrochemical detection coupled with immunoaffinity purification: association with cigarette smoking.
Free radical biology & medicine.
2006 Feb; 40(4):711-20. doi:
10.1016/j.freeradbiomed.2005.09.035. [PMID: 16458202] - Horng-Rong Chang, Chih-Chieh Lai, Jong-Da Lian, Chiu-Chu Lin, Chau-Jong Wang. Formation of 8-nitroguanine in blood of patients with inflammatory gouty arthritis.
Clinica chimica acta; international journal of clinical chemistry.
2005 Dec; 362(1-2):170-5. doi:
10.1016/j.cccn.2005.06.003. [PMID: 16023632] - Somchai Pinlaor, Puangrat Yongvanit, Yusuke Hiraku, Ning Ma, Reiji Semba, Shinji Oikawa, Mariko Murata, Banchob Sripa, Paiboon Sithithaworn, Shosuke Kawanishi. 8-nitroguanine formation in the liver of hamsters infected with Opisthorchis viverrini.
Biochemical and biophysical research communications.
2003 Sep; 309(3):567-71. doi:
10.1016/j.bbrc.2003.08.039. [PMID: 12963027] - Yih-Shou Hsieh, Bi-Chiou Chen, Song-Jui Shiow, Hsue-Chun Wang, Jeng-Dong Hsu, Chau-Jong Wang. Formation of 8-nitroguanine in tobacco cigarette smokers and in tobacco smoke-exposed Wistar rats.
Chemico-biological interactions.
2002 Apr; 140(1):67-80. doi:
10.1016/s0009-2797(02)00018-2. [PMID: 12044561]