Z-Phe-Arg-AMC · HCl (BioDeep_00000755830)
代谢物信息卡片
化学式: C33H36N6O6 (612.2696195999999)
中文名称: 组织蛋白酶L底物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4
InChI: InChI=1S/C33H36N6O6/c1-21-17-29(40)45-28-19-24(14-15-25(21)28)37-30(41)26(13-8-16-36-32(34)35)38-31(42)27(18-22-9-4-2-5-10-22)39-33(43)44-20-23-11-6-3-7-12-23/h2-7,9-12,14-15,17,19,26-27H,8,13,16,18,20H2,1H3,(H,37,41)(H,38,42)(H,39,43)(H4,34,35,36)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Akihiko Tsuji, Kana Tsukamoto, Keiko Iwamoto, Yuka Ito, Keizo Yuasa. Enzymatic characterization of germination-specific cysteine protease-1 expressed transiently in cotyledons during the early phase of germination.
Journal of biochemistry.
2013 Jan; 153(1):73-83. doi:
10.1093/jb/mvs125. [PMID: 23112094] - Marina S Defferrari, Diogo R Demartini, Thiago B Marcelino, Paulo M Pinto, Celia R Carlini. Insecticidal effect of Canavalia ensiformis major urease on nymphs of the milkweed bug Oncopeltus fasciatus and characterization of digestive peptidases.
Insect biochemistry and molecular biology.
2011 Jun; 41(6):388-99. doi:
10.1016/j.ibmb.2011.02.008. [PMID: 21377528] - Kenji Takahashi, Takehiro Suzuki, Wataru Nishii, Keiko Kubota, Chiaki Shibata, Toshiaki Isobe, Naoshi Dohmae. A cysteine endopeptidase ('dionain') is involved in the digestive fluid of Dionaea muscipula (Venus's fly-trap).
Bioscience, biotechnology, and biochemistry.
2011; 75(2):346-8. doi:
10.1271/bbb.100546. [PMID: 21307583] - Camila G R Elias, Ana Carolina Aor, Roberta S Valle, Claudia M d'Avila-Levy, Marta H Branquinha, André L S Santos. Cysteine peptidases from Phytomonas serpens: biochemical and immunological approaches.
FEMS immunology and medical microbiology.
2009 Dec; 57(3):247-56. doi:
10.1111/j.1574-695x.2009.00604.x. [PMID: 19780820] - H Ghoneim, M Q Klinkert. Biochemical properties of purified cathepsin B from Schistosoma mansoni.
International journal for parasitology.
1995 Dec; 25(12):1515-9. doi:
10.1016/0020-7519(95)00079-8. [PMID: 8719966] - J D Lonsdale-Eccles, G W Mpimbaza, Z R Nkhungulu, J Olobo, L Smith, O M Tosomba, D J Grab. Trypanosomatid cysteine protease activity may be enhanced by a kininogen-like moiety from host serum.
The Biochemical journal.
1995 Jan; 305 ( Pt 2)(?):549-56. doi:
10.1042/bj3050549. [PMID: 7832773] - H Okazaki, C Tani, M Ando, K Ishii, S Ishibashi, Y Nishimura, K Kato. Possible involvement of cathepsin L in processing of rat liver hexokinase to eliminate mitochondria-binding ability.
Journal of biochemistry.
1992 Sep; 112(3):409-13. doi:
10.1093/oxfordjournals.jbchem.a123913. [PMID: 1429531] - G C Macadam, R J Beynon, J S Bond. A cryptic meprin-like proteolytic activity in mouse kidney brush border membranes.
The International journal of biochemistry.
1990; 22(9):989-96. doi:
10.1016/0020-711x(90)90205-h. [PMID: 2282966] - W H Baricos, Y Zhou, R W Mason, A J Barrett. Human kidney cathepsins B and L. Characterization and potential role in degradation of glomerular basement membrane.
The Biochemical journal.
1988 May; 252(1):301-4. doi:
10.1042/bj2520301. [PMID: 2844149] - R W Mason, S Gal, M M Gottesman. The identification of the major excreted protein (MEP) from a transformed mouse fibroblast cell line as a catalytically active precursor form of cathepsin L.
The Biochemical journal.
1987 Dec; 248(2):449-54. doi:
10.1042/bj2480449. [PMID: 3435459] - T Okuyama, M Nojima, T Fuchiwaki, H Furuya, S Ishiura, H Sugita. [A high peptidase activity specific for hydrolysis of Z-Phe-Arg-MCA from human serum during pregnancy].
Nihon Sanka Fujinka Gakkai zasshi.
1986 Jun; 38(6):963-4. doi:
NULL. [PMID: 3525704] - S Zucker, D J Buttle, M J Nicklin, A J Barrett. The proteolytic activities of chymopapain, papain, and papaya proteinase III.
Biochimica et biophysica acta.
1985 Apr; 828(2):196-204. doi:
10.1016/0167-4838(85)90057-3. [PMID: 3919769]