Sodium taurochenodeoxycholate (BioDeep_00000755820)
PANOMIX_OTCML-2023 Bile acids
代谢物信息卡片
Taurochenodeoxycholic acid sodium salt
化学式: C26H44NNaO6S (521.2786884000001)
中文名称: 牛磺鹅去氧胆酸钠
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 1.55%
分子结构信息
SMILES: CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C.[Na+]
InChI: /q
描述信息
D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics
D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].
同义名列表
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:195266
- PubChem: 23664008
- ChEMBL: CHEMBL2028546
- CAS: 6009-98-9
- medchemexpress: HY-N1429
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Aliya Ayaz, Abdul Jalal, Zhou Qian, Khalid Ali Khan, Liwang Liu, Chunmei Hu, Ying Li, Xilin Hou. Investigating the effects of tauroursodeoxycholic acid (TUDCA) in mitigating endoplasmic reticulum stress and cellular responses in Pak choi.
Physiologia plantarum.
2024 Mar; 176(2):e14246. doi:
10.1111/ppl.14246. [PMID: 38467573] - Yanbo Chang, Xuejing Li, Jinping Jiang, Lanlan Gui, Linfei Wan, Xiangxiang Zhou, Linchuan Liao, Kexin Li, Ke Lan. Separation of bile acid isomer plays a pivotal role in bioequivalence evaluation of ursodeoxycholic acid.
Journal of pharmaceutical and biomedical analysis.
2024 Feb; 239(?):115882. doi:
10.1016/j.jpba.2023.115882. [PMID: 38071766] - Qiuyue Wang, Wen Li, Xiaozhuo Zhang, Shuet Ling Chung, Jinling Dai, Zhu Jin. Tauroursodeoxycholic acid protects Schwann cells from high glucose-induced cytotoxicity by targeting NLRP3 to regulate cell migration and pyroptosis.
Biotechnology and applied biochemistry.
2024 Feb; 71(1):28-37. doi:
10.1002/bab.2518. [PMID: 37749820] - Na Cui, Wensen Zhang, Fazhi Su, Zhihong Zhang, Weijie Qiao, Yanping Sun, Bingyou Yang, Haixue Kuang, Qiuhong Wang. Metabolomics and Lipidomics Study Unveils the Impact of Tauroursodeoxycholic Acid on Hyperlipidemic Mice.
Molecules (Basel, Switzerland).
2023 Aug; 28(17):. doi:
10.3390/molecules28176352. [PMID: 37687178] - Kelu Lei, Minghao Yuan, Sihui Li, Qiang Zhou, Meifeng Li, Dafu Zeng, Yiping Guo, Li Guo. Performance evaluation of E-nose and E-tongue combined with machine learning for qualitative and quantitative assessment of bear bile powder.
Analytical and bioanalytical chemistry.
2023 Jul; 415(17):3503-3513. doi:
10.1007/s00216-023-04740-5. [PMID: 37199792] - Himanshu Sankrityayan, Vishwadeep Shelke, Ajinath Kale, Anil Bhanudas Gaikwad. Evaluating the potential of tauroursodeoxycholic acid as add-on therapy in amelioration of streptozotocin-induced diabetic kidney disease.
European journal of pharmacology.
2023 Mar; 942(?):175528. doi:
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Clinical science (London, England : 1979).
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Journal of applied toxicology : JAT.
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Biomaterials science.
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