Cefyl (BioDeep_00000755074)
Secondary id: BioDeep_00001899879
代谢物信息卡片
化学式: C20H26ClN5O7S2 (547.0962116000001)
中文名称: 盐酸头孢他美酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)OCOC(=O)C(C)(C)C.Cl
InChI: /m1./s1
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:31369
- PubChem: 5489410
- CAS: 111696-23-2
- CAS: 105629-49-0
- KEGG: C13089
- PubChem: 585153
- NIKKAJI: J430.092K
- KNApSAcK: 31369
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Keumhan Noh, Eunyoung Kim, Wonku Kang. Quantitative determination of cefetamet in human plasma by liquid chromatography-mass spectrometry.
Biomedical chromatography : BMC.
2011 Jul; 25(7):779-82. doi:
10.1002/bmc.1516. [PMID: 20845371] - M Dan, F Poch, A Edelman, J Asherov, H Hafely, Y Atzmon. Serum bactericidal activity of newer oral cephalosporins in healthy volunteers.
The Journal of antimicrobial chemotherapy.
1998 Apr; 41(4):485-8. doi:
10.1093/jac/41.4.485. [PMID: 9598780] - M Nakashima, K Kosuge, I Ishii, M Ohtsubo. [Influence of multiple-dose administration of cefetamet pivoxil on blood and urinary concentrations of carnitine and effects of simultaneous administration of carnitine with cefetamet pivoxil].
The Japanese journal of antibiotics.
1996 Oct; 49(10):966-79. doi:
NULL. [PMID: 8986559] - K Stoeckel, M Harell, M Dan. Penetration of cefetamet pivoxil and cefuroxime axetil into the maxillary sinus mucosa at steady state.
Antimicrobial agents and chemotherapy.
1996 Mar; 40(3):780-3. doi:
10.1128/aac.40.3.780. [PMID: 8851611] - W L Hayton, J Kneer, R de Groot, K Stoeckel. Influence of maturation and growth on cefetamet pivoxil pharmacokinetics: rational dosing for infants.
Antimicrobial agents and chemotherapy.
1996 Mar; 40(3):567-74. doi:
10.1128/aac.40.3.567. [PMID: 8851572] - A Novelli, T Mazzei, S Fallani, R Dei, M I Cassetta, S Conti. Betalactam therapy and intestinal flora.
Journal of chemotherapy (Florence, Italy).
1995 May; 7 Suppl 1(?):25-31. doi:
NULL. [PMID: 8618110] - R A Blouin, K Stoeckel. Cefetamet pivoxil clinical pharmacokinetics.
Clinical pharmacokinetics.
1993 Sep; 25(3):172-88. doi:
10.2165/00003088-199325030-00002. [PMID: 8222459] - M Kissling, U Chadbourne. Literature survey on clinical efficacy and tolerability on cefetamet pivoxil: an analysis of 3,128 cases.
Respiration; international review of thoracic diseases.
1993; 60 Suppl 1(?):45-54. doi:
10.1159/000196249. [PMID: 8480090] - W L Hayton, R A Walstad, E Thurmann-Nielsen, T Kufaas, J Kneer, R J Ambros, H E Rugstad, E Monn, E Bodd, K Stoeckel. Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in children.
Antimicrobial agents and chemotherapy.
1991 Apr; 35(4):720-5. doi:
10.1128/aac.35.4.720. [PMID: 2069377] - R A Blouin, J Kneer, R J Ambros, K Stoeckel. Influence of antacid and ranitidine on the pharmacokinetics of oral cefetamet pivoxil.
Antimicrobial agents and chemotherapy.
1990 Sep; 34(9):1744-8. doi:
10.1128/aac.34.9.1744. [PMID: 1981000] - Y K Tam, J Kneer, U C Dubach, K Stoeckel. Effects of timing of food and fluid volume on cefetamet pivoxil absorption in healthy normal volunteers.
Antimicrobial agents and chemotherapy.
1990 Aug; 34(8):1556-9. doi:
10.1128/aac.34.8.1556. [PMID: 2221865] - W L Hayton, J Kneer, R A Blouin, K Stoeckel. Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with hepatic cirrhosis.
Antimicrobial agents and chemotherapy.
1990 Jul; 34(7):1318-22. doi:
10.1128/aac.34.7.1318. [PMID: 2386364] - C Stathakis, N Roulleau, M Libert, G Germano, M Kissling. Cefetamet pivoxil in acute pyelonephritis: an open study.
Current medical research and opinion.
1990; 12(1):43-50. doi:
10.1185/03007999009111490. [PMID: 2188796] - J Kneer, Y K Tam, R A Blouin, F J Frey, E Keller, C Stathakis, B Luginbuehl, K Stoeckel. Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with renal insufficiency.
Antimicrobial agents and chemotherapy.
1989 Nov; 33(11):1952-7. doi:
10.1128/aac.33.11.1952. [PMID: 2610506] - Y K Tam, J Kneer, U C Dubach, K Stoeckel. Pharmacokinetics of cefetamet pivoxil (Ro 15-8075) with ascending oral doses in normal healthy volunteers.
Antimicrobial agents and chemotherapy.
1989 Jun; 33(6):957-9. doi:
10.1128/aac.33.6.957. [PMID: 2764545] - R A Blouin, J Kneer, K Stoeckel. Pharmacokinetics of intravenous cefetamet (Ro 15-8074) and oral cefetamet pivoxil (Ro 15-8075) in young and elderly subjects.
Antimicrobial agents and chemotherapy.
1989 Mar; 33(3):291-6. doi:
10.1128/aac.33.3.291. [PMID: 2729925] - K Stoeckel, Y K Tam, J Kneer. Pharmacokinetics of oral cefetamet pivoxil (Ro 15-8075) and intravenous cefetamet (Ro 15-8074) in humans: a review.
Current medical research and opinion.
1989; 11(7):432-41. doi:
10.1185/03007998909115930. [PMID: 2673663] - R Wyss, F Bucheli. Determination of cefetamet and its orally active ester, cefetamet pivoxyl, in biological fluids by high-performance liquid chromatography.
Journal of chromatography.
1988 Aug; 430(1):81-92. doi:
10.1016/s0378-4347(00)83136-9. [PMID: 3215964] - J R Koup, U C Dubach, R Brandt, R Wyss, K Stoeckel. Pharmacokinetics of cefetamet (Ro 15-8074) and cefetamet pivoxil (Ro 15-8075) after intravenous and oral doses in humans.
Antimicrobial agents and chemotherapy.
1988 Apr; 32(4):573-9. doi:
10.1128/aac.32.4.573. [PMID: 3377466]