Sodium Benzoate (BioDeep_00000754847)
代谢物信息卡片
Sodium Benzoate
化学式: C7H5NaO2 (144.01872300000002)
中文名称: 苯甲酸钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C(=O)[O-].[Na+]
InChI: /q
描述信息
A - Alimentary tract and metabolism > A16 - Other alimentary tract and metabolism products > A16A - Other alimentary tract and metabolism products > A16AX - Various alimentary tract and metabolism products
An organic sodium salt resulting from the replacement of the proton from the carboxy group of benzoic acid by a sodium ion.
D000074385 - Food Ingredients > D005503 - Food Additives > D005520 - Food Preservatives
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
同义名列表
1 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:113455
- KEGGdrug: D02277
- PubChem: 517055
- ChEMBL: CHEMBL1356
- MeSH: Sodium Benzoate
- CAS: 532-32-1
- MetaboLights: MTBLC113455
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chieh-Hsin Lin, Hsin-Yi Liao, Hsien-Yuan Lane, Chao-Jung Chen. Elucidating the Mechanisms of Sodium Benzoate in Alzheimer's Disease: Insights from Quantitative Proteomics Analysis of Serum Samples.
The international journal of neuropsychopharmacology.
2023 Oct; ?(?):. doi:
10.1093/ijnp/pyad061. [PMID: 37875373] - Folake Olubukola Asejeje, Khalid Damilare Akinola, Michael Abayomi Abiola. Sodium benzoate exacerbates hepatic oxidative stress and inflammation in lipopolysaccharide-induced liver injury in rats.
Immunopharmacology and immunotoxicology.
2023 Oct; 45(5):558-564. doi:
10.1080/08923973.2023.2191818. [PMID: 36927185] - Afaf Abdullah Al-Shelash, Heba Fawzy Gomaa. Prospective Effect of Nano-Selenium Particles on Thyroid Dysfunction and Oxidative Stress Induced by Sodium Benzoate in Male Albino Rats.
Pakistan journal of biological sciences : PJBS.
2023 May; 26(6):334-346. doi:
10.3923/pjbs.2023.334.346. [PMID: 37902047] - Eman E Yassien, Amina M S Mohamed, Magda E Mahmoud, Adel M Zaki. Sodium benzoate induced toxicities in albino male rats: mitigating effects of Ficus carica and Cymbopogon citratus leave extract.
Environmental science and pollution research international.
2022 Dec; 29(60):90567-90579. doi:
10.1007/s11356-022-22020-0. [PMID: 35871196] - Damir Suljević, Maja Mitrašinović-Brulić, Amela Dervišević, Muhamed Fočak. Protective role of the dandelion extract against the blood-liver axis, cell membranes, and anemia disorder in sodium benzoate-exposed rats.
Cell biochemistry and function.
2022 Dec; 40(8):946-958. doi:
10.1002/cbf.3756. [PMID: 36210509] - A Mukherjee, R Patel, P Zaveri, M T Shah, N S Munshi. Microbial fuel cell performance for aromatic hydrocarbon bioremediation and common effluent treatment plant wastewater treatment with bioelectricity generation through series-parallel connection.
Letters in applied microbiology.
2022 Oct; 75(4):785-795. doi:
10.1111/lam.13612. [PMID: 34821400] - Ishfaq Shafi Khan, Khalid Bashir Dar, Showkat Ahmad Ganie, Md Niamat Ali. Toxicological impact of sodium benzoate on inflammatory cytokines, oxidative stress and biochemical markers in male Wistar rats.
Drug and chemical toxicology.
2022 May; 45(3):1345-1354. doi:
10.1080/01480545.2020.1825472. [PMID: 33003957] - Lourdes Soto-Muñoz, Victoria Martínez-Blay, María B Pérez-Gago, Asunción Fernández-Catalán, Maricruz Argente-Sanchis, Lluís Palou. Starch-based antifungal edible coatings to control sour rot caused by Geotrichum citri-aurantii and maintain postharvest quality of 'Fino' lemon.
Journal of the science of food and agriculture.
2022 Jan; 102(2):794-800. doi:
10.1002/jsfa.11414. [PMID: 34223648] - Andrea Baker, Lachlan Clarke, Peter Donovan, Jacobus P J Ungerer, Gunter Hartel, George Bruxner, Luca Cocchi, Anne Gordon, Vikas Moudgil, Gail Robinson, Digant Roy, Ravinder Sohal, Emma Whittle, James G Scott. Cadence discovery: study protocol for a dose-finding and mechanism of action clinical trial of sodium benzoate in people with treatment-refractory schizophrenia.
Trials.
2021 Dec; 22(1):918. doi:
10.1186/s13063-021-05890-6. [PMID: 34903265] - Ali Acar. Therapeutic effects of royal jelly against sodium benzoate-induced toxicity: cytotoxic, genotoxic, and biochemical assessment.
Environmental science and pollution research international.
2021 Jul; 28(26):34410-34425. doi:
10.1007/s11356-021-13172-6. [PMID: 33646542] - Hao Cui, Yao Dong, Tenghui Lu, Xintong Zou, Mingxin Wang, Xiudong Yang, Hongli Zhou. Effect of ethanolic extract from Morus alba L. leaves on the quality and sensory aspects of chilled pork under retail conditions.
Meat science.
2021 Feb; 172(?):108368. doi:
10.1016/j.meatsci.2020.108368. [PMID: 33229104] - Cristina F Malla, Natalia A Mireles, Ana S Ramírez, José B Poveda, María M Tavío. Aspirin, sodium benzoate and sodium salicylate reverse resistance to colistin in Enterobacteriaceae and Pseudomonas aeruginosa.
The Journal of antimicrobial chemotherapy.
2020 12; 75(12):3568-3575. doi:
10.1093/jac/dkaa371. [PMID: 32989461] - Lamiaa El-Shennawy, Maher Abd El-Naby Kamel, Asmaa Hassan Younis Khalaf, Mokhtar Ibrahim Yousef. Dose-dependent reproductive toxicity of sodium benzoate in male rats: Inflammation, oxidative stress and apoptosis.
Reproductive toxicology (Elmsford, N.Y.).
2020 12; 98(?):92-98. doi:
10.1016/j.reprotox.2020.08.014. [PMID: 32911041] - Ross Mangum, Claudia Soler-Alfonso, Sherri Birchansky, Alexandra Stevens. Survival and Neurologic Recovery After Prompt Diagnosis and Aggressive Management of Severe Idiopathic Hyperammonemic Encephalopathy in a Patient with Acute Myeloid Leukemia.
Journal of pediatric hematology/oncology.
2020 08; 42(6):e452-e455. doi:
10.1097/mph.0000000000001579. [PMID: 31415019] - Rupesh Raina, Jirair K Bedoyan, Uta Lichter-Konecki, Philippe Jouvet, Stefano Picca, Nicholas Ah Mew, Marcel C Machado, Ronith Chakraborty, Meghana Vemuganti, Manpreet K Grewal, Timothy Bunchman, Sidharth Kumar Sethi, Vinod Krishnappa, Mignon McCulloch, Khalid Alhasan, Arvind Bagga, Rajit K Basu, Franz Schaefer, Guido Filler, Bradley A Warady. Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy.
Nature reviews. Nephrology.
2020 08; 16(8):471-482. doi:
10.1038/s41581-020-0267-8. [PMID: 32269302] - Érica B da Silva, Rebecca M Savage, Amy S Biddle, Stephanie A Polukis, Megan L Smith, Limin Kung. Effects of a chemical additive on the fermentation, microbial communities, and aerobic stability of corn silage with or without air stress during storage.
Journal of animal science.
2020 Aug; 98(8):. doi:
10.1093/jas/skaa246. [PMID: 32756961] - Y Zhang, Y Liu, Q Meng, Z Zhou, H Wu. A mixture of potassium sorbate and sodium benzoate improved fermentation quality of whole-plant corn silage by shifting bacterial communities.
Journal of applied microbiology.
2020 May; 128(5):1312-1323. doi:
10.1111/jam.14571. [PMID: 31894885] - Zandisiwe E Magwebu, Mikateko Mazinu, Sahar Abdul-Rasool, Chesa G Chauke. The effect of hyperglycinemic treatment in captive-bred Vervet monkeys (Chlorocebus aethiops).
Metabolic brain disease.
2019 10; 34(5):1467-1472. doi:
10.1007/s11011-019-00449-6. [PMID: 31230217] - W P Santos, G G S Salvati, J M Silveira, P A R Salvo, B A V Arthur, V C Gritti, K S Oliveira, M V Ferraz, J L P Daniel, L G Nussio. The effect of length of storage and sodium benzoate on the nutritive value of reconstituted sorghum grain silages for dairy cows.
Journal of dairy science.
2019 Oct; 102(10):9028-9038. doi:
10.3168/jds.2019-16759. [PMID: 31421881] - Hossein Mohammadzadeh-Aghdash, Nader Akbari, Karim Esazadeh, Jafar Ezzati Nazhad Dolatabadi. Molecular and technical aspects on the interaction of serum albumin with multifunctional food preservatives.
Food chemistry.
2019 Sep; 293(?):491-498. doi:
10.1016/j.foodchem.2019.04.119. [PMID: 31151640] - Dhruv Patel, Arundhati Jana, Avik Roy, Kalipada Pahan. Cinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson's Disease Via Astrocytic GDNF.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.
2019 09; 14(3):503-518. doi:
10.1007/s11481-019-09855-0. [PMID: 31119595] - S Giva, J Finnegan, P Ihidero, G Maguire, B Power, I Knerr, A Monavari. Hyperammonaemia in Neonates and Young Children: Potential Metabolic Causes, Diagnostic Approaches and Clinical Consequences.
Irish medical journal.
2019 01; 112(1):858. doi:
NULL. [PMID: 30719899] - Limin Kung, Megan L Smith, Erica Benjamim da Silva, Michelle C Windle, Thiago C da Silva, Stephanie A Polukis. An evaluation of the effectiveness of a chemical additive based on sodium benzoate, potassium sorbate, and sodium nitrite on the fermentation and aerobic stability of corn silage.
Journal of dairy science.
2018 Jul; 101(7):5949-5960. doi:
10.3168/jds.2017-14006. [PMID: 29655557] - Yael Wilnai, Yair J Blumenfeld, Kristina Cusmano, Susan R Hintz, Deborah Alcorn, William E Benitz, William E Berquist, Jonathan A Bernstein, Ricardo O Castillo, Waldo Concepcion, Tina M Cowan, Kenneth L Cox, Deirdre J Lyell, Carlos O Esquivel, Margaret Homeyer, Louanne Hudgins, Melissa Hurwitz, Jonathan P Palma, Susan Schelley, Vishnu Priya Akula, Marshall L Summar, Gregory M Enns. Prenatal treatment of ornithine transcarbamylase deficiency.
Molecular genetics and metabolism.
2018 03; 123(3):297-300. doi:
10.1016/j.ymgme.2018.01.004. [PMID: 29396029] - Mohammad Javad Khoshnoud, Asma Siavashpour, Mojgan Bakhshizadeh, Marzieh Rashedinia. Effects of sodium benzoate, a commonly used food preservative, on learning, memory, and oxidative stress in brain of mice.
Journal of biochemical and molecular toxicology.
2018 Feb; 32(2):. doi:
10.1002/jbt.22022. [PMID: 29243862] - G van Straten, M G M de Sain-van der Velden, I M van Geijlswijk, R P Favier, S J Mesu, N E Holwerda-Loof, M van der Ham, H Fieten, J Rothuizen, B Spee, N M Verhoeven-Duif. Saline is as effective as nitrogen scavengers for treatment of hyperammonemia.
Scientific reports.
2017 10; 7(1):13112. doi:
10.1038/s41598-017-12686-9. [PMID: 29030642] - Anne H O'Donnell-Luria, Alexander P Lin, Sai K Merugumala, Frances Rohr, Susan E Waisbren, Rebecca Lynch, Vatche Tchekmedyian, Aaron D Goldberg, Andrew Bellinger, J Ricardo McFaline-Figueroa, Tracey Simon, Esteban F Gershanik, Bruce D Levy, David E Cohen, Martin A Samuels, Gerard T Berry, Natasha Y Frank. Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma.
Molecular genetics and metabolism.
2017 05; 121(1):9-15. doi:
10.1016/j.ymgme.2017.03.003. [PMID: 28408159] - Alex Ryan, Andrea Baker, Frances Dark, Sharon Foley, Anne Gordon, Sean Hatherill, Stephen Stathis, Sukanta Saha, George Bruxner, Martin Beckman, Drew Richardson, Michael Berk, Olivia Dean, John McGrath, Cadence Working Group, James Scott. The efficacy of sodium benzoate as an adjunctive treatment in early psychosis - CADENCE-BZ: study protocol for a randomized controlled trial.
Trials.
2017 04; 18(1):165. doi:
10.1186/s13063-017-1908-5. [PMID: 28388932] - Dennis J Orton, Jessica L Gifford, Isolde Seiden-Long, Aneal Khan, Lawrence de Koning. Critically High Plasma Ammonia in an Adolescent Girl.
Clinical chemistry.
2016 12; 62(12):1565-1568. doi:
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The Journal of pediatrics.
2016 Mar; 170(?):234-9. doi:
10.1016/j.jpeds.2015.12.027. [PMID: 26749113] - Catherine Chen, Karen B Bain, Jennifer A Iuppa, Roger D Yusen, Derek E Byers, George A Patterson, Elbert P Trulock, Ramsey R Hachem, Chad A Witt. Hyperammonemia Syndrome After Lung Transplantation: A Single Center Experience.
Transplantation.
2016 Mar; 100(3):678-84. doi:
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Australian dental journal.
2015 Sep; 60(3):368-74. doi:
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International journal of food microbiology.
2015 Jul; 204(?):111-7. doi:
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European journal of clinical nutrition.
2015 Jul; 69(7):781-5. doi:
10.1038/ejcn.2015.80. [PMID: 26014268] - Akiko Matsuura, Yuko Fujita, Masaomi Iyo, Kenji Hashimoto. Effects of sodium benzoate on pre-pulse inhibition deficits and hyperlocomotion in mice after administration of phencyclidine.
Acta neuropsychiatrica.
2015 Jun; 27(3):159-67. doi:
10.1017/neu.2015.1. [PMID: 25648314] - Nicholas F Blair, Philip D Cremer, Michel C Tchan. Urea cycle disorders: a life-threatening yet treatable cause of metabolic encephalopathy in adults.
Practical neurology.
2015 Feb; 15(1):45-8. doi:
10.1136/practneurol-2014-000916. [PMID: 25125564] - Belinda S Lennerz, Scott B Vafai, Nigel F Delaney, Clary B Clish, Amy A Deik, Kerry A Pierce, David S Ludwig, Vamsi K Mootha. Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans.
Molecular genetics and metabolism.
2015 Jan; 114(1):73-9. doi:
10.1016/j.ymgme.2014.11.010. [PMID: 25497115] - C Eckert, M Pein, J Breitkreutz. Lean production of taste improved lipidic sodium benzoate formulations.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2014 Oct; 88(2):455-61. doi:
10.1016/j.ejpb.2014.05.013. [PMID: 24859305] - Saurabh Khasnavis, Kalipada Pahan. Cinnamon treatment upregulates neuroprotective proteins Parkin and DJ-1 and protects dopaminergic neurons in a mouse model of Parkinson's disease.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.
2014 Sep; 9(4):569-81. doi:
10.1007/s11481-014-9552-2. [PMID: 24946862] - A A Gabriel, S K P Salazar. Evaluation of sodium benzoate and licorice (Glycyrrhiza glabra) root extract as heat-sensitizing additives against Escherichia coli O157:H7 in mildly heated young coconut liquid endosperm.
Letters in applied microbiology.
2014 Aug; 59(2):139-46. doi:
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Pediatric neurology.
2014 Jul; 51(1):133-7. doi:
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Arquivos brasileiros de endocrinologia e metabologia.
2014 Apr; 58(3):237-42. doi:
10.1590/0004-2730000002821. [PMID: 24863085] - Gamze Yetuk, Dilek Pandir, Hatice Bas. Protective role of catechin and quercetin in sodium benzoate-induced lipid peroxidation and the antioxidant system in human erythrocytes in vitro.
TheScientificWorldJournal.
2014; 2014(?):874824. doi:
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Molecular genetics and metabolism.
2014 Jan; 111(1):16-25. doi:
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Journal of biomolecular structure & dynamics.
2014; 32(3):438-47. doi:
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Toxicology and industrial health.
2013 Sep; 29(8):697-703. doi:
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Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.
2013 Jun; 8(3):739-55. doi:
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Journal of Korean medical science.
2012 Aug; 27(8):961-4. doi:
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Molecular genetics and metabolism.
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Chemistry & biodiversity.
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