Thimerosal (BioDeep_00000754459)
代谢物信息卡片
化学式: C9H9HgNaO2S (405.99272540000004)
中文名称: 硫柳汞钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC[Hg]SC1=CC=CC=C1C(=O)[O-].[Na+]
InChI: /q
描述信息
D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AK - Mercurial products
D010575 - Pesticides > D005659 - Fungicides, Industrial > D005035 - Ethylmercury Compounds
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D010592 - Pharmaceutic Aids
同义名列表
2 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:9546
- KEGGdrug: D00864
- PubChem: 16684434
- DrugBank: DB11590
- MeSH: Thimerosal
- CAS: 54-64-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yang Jiang, Sha Wang, Jing Lyu, Jiajia Li, Qingchun Diao. Contact dermatitis associated with a cosmetic cream.
Journal of cosmetic dermatology.
2022 Oct; 21(10):4479-4481. doi:
10.1111/jocd.14847
. [PMID: 35156746] - Marcos V S Sales, Reginaldo C da Silva Filho, Marina M Silva, Jeanynne L Rocha, Ricardo O Freire, Eloiza Lopes de L Tanabe, Elaine C O Silva, Eduardo Jorge S Fonseca, Isis M Figueiredo, Ueslen Rocha, Josué Carinhanha C Santos, Ana Catarina R Leite. Consequences of thimerosal on human erythrocyte hemoglobin: Assessing functional and structural protein changes induced by an organic mercury compound.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2022 May; 71(?):126928. doi:
10.1016/j.jtemb.2022.126928
. [PMID: 35032836] - Marcella R Aquino, Theresa A Bingemann, Anil Nanda, Kelly M Maples. Delayed allergic skin reactions to vaccines.
Allergy and asthma proceedings.
2022 01; 43(1):20-29. doi:
10.2500/aap.2022.43.210105
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Human & experimental toxicology.
2022 Jan; 41(?):9603271221136206. doi:
10.1177/09603271221136206
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Brazilian journal of biology = Revista brasleira de biologia.
2021; 83(?):e242942. doi:
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. [PMID: 34468508] - Shauni Lien Geeraerts, Kim Rosalie Kampen, Gianmarco Rinaldi, Purvi Gupta, Mélanie Planque, Nikolaos Louros, Elien Heylen, Kaat De Cremer, Katrijn De Brucker, Stijn Vereecke, Benno Verbelen, Pieter Vermeersch, Joost Schymkowitz, Frederic Rousseau, David Cassiman, Sarah-Maria Fendt, Arnout Voet, Bruno P A Cammue, Karin Thevissen, Kim De Keersmaecker. Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth.
Molecular cancer therapeutics.
2021 01; 20(1):50-63. doi:
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Dermatitis : contact, atopic, occupational, drug.
2020 Nov; 31(6):367-372. doi:
10.1097/der.0000000000000674
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mSphere.
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Contact dermatitis.
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2018 Dec; 50(?):100-104. doi:
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Scientific reports.
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2018 Jul; 184(1):7-15. doi:
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International journal of biological macromolecules.
2018 Jul; 113(?):1032-1040. doi:
10.1016/j.ijbiomac.2018.02.116
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2017 Nov; 91(6):657-664. doi:
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Metallomics : integrated biometal science.
2017 08; 9(8):1060-1072. doi:
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. [PMID: 28702563] - Mario Suwalsky, Pablo Zambrano, María José Gallardo, Fernando Villena, Malgorzata Jemiola-Rzeminska, Kazimierz Strzalka. Effects of Thimerosal on Lipid Bilayers and Human Erythrocytes: An In Vitro Study.
The Journal of membrane biology.
2016 12; 249(6):823-831. doi:
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Contact dermatitis.
2016 Oct; 75(4):223-9. doi:
10.1111/cod.12587
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Antiviral research.
2016 08; 132(?):92-8. doi:
10.1016/j.antiviral.2016.05.018
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Toxicology.
2016 Mar; 347-349(?):1-5. doi:
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. [PMID: 26945727] - Maria Fernanda Hornos Carneiro, Christudas Morais, David M Small, David A Vesey, Fernando Barbosa, Glenda C Gobe. Thimerosal induces apoptotic and fibrotic changes to kidney epithelial cells in vitro.
Environmental toxicology.
2015 Dec; 30(12):1423-33. doi:
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Environmental research.
2014 Oct; 134(?):218-27. doi:
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. [PMID: 25173055] - Stefan Trümpler, Björn Meermann, Sascha Nowak, Wolfgang Buscher, Uwe Karst, Michael Sperling. In vitro study of thimerosal reactions in human whole blood and plasma surrogate samples.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2014 Apr; 28(2):125-130. doi:
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Analytical and bioanalytical chemistry.
2014 Mar; 406(7):1909-16. doi:
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Journal of cosmetic dermatology.
2014 Mar; 13(1):68-71. doi:
10.1111/jocd.12078
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Cell calcium.
2013 May; 53(5-6):357-65. doi:
10.1016/j.ceca.2013.03.004
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Journal of biomedicine & biotechnology.
2012; 2012(?):256965. doi:
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Biology of reproduction.
2011 Aug; 85(2):296-305. doi:
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American journal of physiology. Gastrointestinal and liver physiology.
2011 Jun; 300(6):G1105-14. doi:
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. [PMID: 21393430] - Jairo L Rodrigues, Juliana M Serpeloni, Bruno L Batista, Samuel S Souza, Fernando Barbosa. Identification and distribution of mercury species in rat tissues following administration of thimerosal or methylmercury.
Archives of toxicology.
2010 Nov; 84(11):891-6. doi:
10.1007/s00204-010-0538-4
. [PMID: 20386881] - E Zieminska, B Toczylowska, A Stafiej, J W Lazarewicz. Low molecular weight thiols reduce thimerosal neurotoxicity in vitro: modulation by proteins.
Toxicology.
2010 Oct; 276(3):154-63. doi:
10.1016/j.tox.2010.07.023
. [PMID: 20696200] - Camille Migdal, Lucie Foggia, Magalie Tailhardat, Pascal Courtellemont, Marek Haftek, Mireille Serres. Sensitization effect of thimerosal is mediated in vitro via reactive oxygen species and calcium signaling.
Toxicology.
2010 Jul; 274(1-3):1-9. doi:
10.1016/j.tox.2010.04.016
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Talanta.
2010 Jan; 80(3):1158-63. doi:
10.1016/j.talanta.2009.09.001
. [PMID: 20006068] - Mieszko Olczak, Michalina Duszczyk, Pawel Mierzejewski, Maria Dorota Majewska. Neonatal administration of a vaccine preservative, thimerosal, produces lasting impairment of nociception and apparent activation of opioid system in rats.
Brain research.
2009 Dec; 1301(?):143-51. doi:
10.1016/j.brainres.2009.09.003
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The Journal of pediatrics.
2009 Oct; 155(4):495-9. doi:
10.1016/j.jpeds.2009.04.011
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2009 Aug; 23(8):2374-83. doi:
10.1096/fj.08-128926
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Analytical chemistry.
2008 Sep; 80(18):7043-50. doi:
10.1021/ac8011126
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Chemical research in toxicology.
2008 Feb; 21(2):483-93. doi:
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Pediatrics.
2008 Feb; 121(2):e208-14. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2008 Feb; 101(2):294-309. doi:
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Current medicinal chemistry.
2008; 15(28):3000-10. doi:
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Journal of toxicology and environmental health. Part A.
2007 Dec; 70(24):2092-5. doi:
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American journal of physiology. Cell physiology.
2007 Jul; 293(1):C162-71. doi:
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Developmental biology.
2007 Mar; 303(1):214-21. doi:
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Toxicology.
2007 Jan; 229(1-2):23-32. doi:
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International journal of toxicology.
2007 Jan; 26(1):57-69. doi:
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Journal of applied toxicology : JAT.
2006 Nov; 26(6):536-9. doi:
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Environmental health perspectives.
2006 Jul; 114(7):1083-91. doi:
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Toxicology and applied pharmacology.
2006 Jul; 214(1):43-54. doi:
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2006 Jun; 17(4):291-6. doi:
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Pediatric dermatology.
2006 Mar; 23(2):117-20. doi:
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American journal of kidney diseases : the official journal of the National Kidney Foundation.
2006 Feb; 47(2):e31-4. doi:
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Journal of agricultural and food chemistry.
2005 Dec; 53(26):10248-53. doi:
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2005 Apr; 204(2):109-21. doi:
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2004 Dec; 154(3):183-9. doi:
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The Journal of biological chemistry.
2004 Sep; 279(39):40385-91. doi:
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Ugeskrift for laeger.
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Journal of biomedical science.
2004 Sep; 11(5):607-10. doi:
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Journal of AOAC International.
2004 Mar; 87(2):424-8. doi:
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. [PMID: 15164837] - S Havarinasab, L Lambertsson, J Qvarnström, P Hultman. Dose-response study of thimerosal-induced murine systemic autoimmunity.
Toxicology and applied pharmacology.
2004 Jan; 194(2):169-79. doi:
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Blood purification.
2004; 22(5):435-9. doi:
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JAMA.
2003 Oct; 290(13):1763-6. doi:
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Pharmacology & toxicology.
2003 Sep; 93(3):123-7. doi:
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. [PMID: 12969436] - Johanna Qvarnström, Lars Lambertsson, Said Havarinasab, Per Hultman, Wolfgang Frech. Determination of methylmercury, ethylmercury, and inorganic mercury in mouse tissues, following administration of thimerosal, by species-specific isotope dilution GC-inductively coupled plasma-MS.
Analytical chemistry.
2003 Aug; 75(16):4120-4. doi:
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. [PMID: 14632125] - Ricardo Bull, Juan José Marengo, José Pablo Finkelstein, María Isabel Behrens, Osvaldo Alvarez. SH oxidation coordinates subunits of rat brain ryanodine receptor channels activated by calcium and ATP.
American journal of physiology. Cell physiology.
2003 Jul; 285(1):C119-28. doi:
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