Bedoradrine (BioDeep_00000752569)

   


代谢物信息卡片


2-[[(7S)-7-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(2-hydroxyethyl)phenyl]ethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]-N,N-dimethylacetamide

化学式: C24H32N2O5 (428.2311102)
中文名称: 贝多拉君
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN(C)C(=O)COC1=CC2=C(CCC(C2)NCC(C3=CC(=C(C=C3)O)CCO)O)C=C1
InChI: InChI=1S/C24H32N2O5/c1-26(2)24(30)15-31-21-7-4-16-3-6-20(12-19(16)13-21)25-14-23(29)17-5-8-22(28)18(11-17)9-10-27/h4-5,7-8,11,13,20,23,25,27-29H,3,6,9-10,12,14-15H2,1-2H3/t20-,23-/m0/s1

描述信息

C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist

同义名列表

2 个代谢物同义名

2-[[(7S)-7-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(2-hydroxyethyl)phenyl]ethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]-N,N-dimethylacetamide; Bedoradrine



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nicholas Gross. The COPD pipeline XX. COPD. 2013 Feb; 10(1):104-6. doi: 10.3109/15412555.2013.766103. [PMID: 23413896]
  • Kazuko Matsuda, Malath Makhay, Kirk Johnson, Yuichi Iwaki. Evaluation of bedoradrine sulfate (MN-221), a novel, highly selective beta2-adrenergic receptor agonist for the treatment of asthma via intravenous infusion. The Journal of asthma : official journal of the Association for the Care of Asthma. 2012 Dec; 49(10):1071-8. doi: 10.3109/02770903.2012.729631. [PMID: 23094708]
  • Yoshio Furihata, Mamoru Kobayashi, Masami Kojima, Kaoru Kobayashi, Tatsuhiko Kawarabayashi, Toshinori Yamamoto. Effects of KUR-1246, a selective uterine relaxant, on transplacental passage and transmigration to milk. The journal of obstetrics and gynaecology research. 2006 Feb; 32(1):4-9. doi: 10.1111/j.1447-0756.2006.00363.x. [PMID: 16445519]
  • Yoshio Furihata, Yoshiyuki Motokawa, Satoshi Murata, Sumiyoshi Kiguchi, Mamoru Kobayashi, Makoto Murakami, Masami Kojima, Toshinori Yamamoto. Cardiovascular effects of KUR-1246, a new tetrahydronaphthalen derivative beta2-adrenoceptor agonist and a selective uterine relaxant. Arzneimittel-Forschung. 2006; 56(1):18-24. doi: 10.1055/s-0031-1296696. [PMID: 16478001]
  • Satoshi Murata, Tadashi Matsuda, Sumiyoshi Kiguchi, Mamoru Kobayashi, Kazutoshi Cho, Kazuhiko Okuyama. Effects of long term administration of KUR-1246, a selective beta(2)-adrenoceptor agonist, on pregnant sheep and their fetuses. BJOG : an international journal of obstetrics and gynaecology. 2005 Jan; 112(1):69-74. doi: 10.1111/j.1471-0528.2004.00333.x. [PMID: 15663400]
  • Sumiyoshi Kiguchi, Tadashi Matsuda, Kazutoshi Cho, Kazuhiko Okuyama, Masuo Akahane, Seiichiro Fujimoto. KUR-1246, a novel beta(2)-adrenoceptor agonist, as a tocolytic agent. Obstetrics and gynecology. 2002 Sep; 100(3):487-94. doi: 10.1016/s0029-7844(02)02141-5. [PMID: 12220768]