PYRROLIDINE-2-CARBALDEHYDE (BioDeep_00000751200)
代谢物信息卡片
(4-CHLORO-PYRIMIDIN-2-YL)-ISOPROPYL-AMINE
化学式: C5H9NO (99.0684104)
中文名称: 吡咯烷-2-甲醛
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(NC1)C=O
InChI: InChI=1S/C5H9NO/c7-4-5-2-1-3-6-5/h4-6H,1-3H2
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gunnar Schley, Bernd Klanke, Johannes Schödel, Sven Kröning, Gazi Türkoglu, Andreas Beyer, Yohannes Hagos, Kerstin Amann, Birgitta C Burckhardt, Nicolai Burzlaff, Kai-Uwe Eckardt, Carsten Willam. Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues.
The American journal of pathology.
2012 Nov; 181(5):1595-606. doi:
10.1016/j.ajpath.2012.07.010. [PMID: 22944601] - Qing Zhu, Miao Liu, Wei-Qing Han, Pin-Lan Li, Zhengchao Wang, Ningjun Li. Overexpression of HIF prolyl-hydoxylase-2 transgene in the renal medulla induced a salt sensitive hypertension.
Journal of cellular and molecular medicine.
2012 Nov; 16(11):2701-7. doi:
10.1111/j.1582-4934.2012.01590.x. [PMID: 22686466] - Peter J Gollan, Mrinal Bhave, Eva-Mari Aro. The FKBP families of higher plants: Exploring the structures and functions of protein interaction specialists.
FEBS letters.
2012 Oct; 586(20):3539-47. doi:
10.1016/j.febslet.2012.09.002. [PMID: 22982859] - Anu Laitala, Ellinoora Aro, Gail Walkinshaw, Joni M Mäki, Maarit Rossi, Minna Heikkilä, Eeva-Riitta Savolainen, Michael Arend, Kari I Kivirikko, Peppi Koivunen, Johanna Myllyharju. Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.
Blood.
2012 Oct; 120(16):3336-44. doi:
10.1182/blood-2012-07-441824. [PMID: 22955912] - Yohannes Hagos, Gunnar Schley, Johannes Schödel, Wolfgang Krick, Gerhard Burckhardt, Carsten Willam, Birgitta C Burckhardt. α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4).
Pflugers Archiv : European journal of physiology.
2012 Oct; 464(4):367-74. doi:
10.1007/s00424-012-1140-9. [PMID: 22875277] - Zhang Yang, Eric P Bennett, Bodil Jørgensen, Damian P Drew, Emma Arigi, Ulla Mandel, Peter Ulvskov, Steven B Levery, Henrik Clausen, Bent L Petersen. Toward stable genetic engineering of human O-glycosylation in plants.
Plant physiology.
2012 Sep; 160(1):450-63. doi:
10.1104/pp.112.198200. [PMID: 22791304] - Kelly C Heim, Paul Angers, Sebastien Léonhart, Barry W Ritz. Anti-inflammatory and neuroactive properties of selected fruit extracts.
Journal of medicinal food.
2012 Sep; 15(9):851-4. doi:
10.1089/jmf.2011.0265. [PMID: 22871089] - Daniela Macconi, Susanna Tomasoni, Paola Romagnani, Piera Trionfini, Fabio Sangalli, Benedetta Mazzinghi, Paola Rizzo, Elena Lazzeri, Mauro Abbate, Giuseppe Remuzzi, Ariela Benigni. MicroRNA-324-3p promotes renal fibrosis and is a target of ACE inhibition.
Journal of the American Society of Nephrology : JASN.
2012 Sep; 23(9):1496-505. doi:
10.1681/asn.2011121144. [PMID: 22822076] - Aikseng Ooi, Kyle A Furge. Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factors.
Chinese journal of cancer.
2012 Sep; 31(9):413-20. doi:
10.5732/cjc.012.10102. [PMID: 22776233] - Judit Kiss, Martin Mollenhauer, Sarah R Walmsley, Johanna Kirchberg, Praveen Radhakrishnan, Thomas Niemietz, Johanna Dudda, Gunnar Steinert, Moira K B Whyte, Peter Carmeliet, Massimiliano Mazzone, Jürgen Weitz, Martin Schneider. Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Journal of immunology (Baltimore, Md. : 1950).
2012 Aug; 189(4):1955-65. doi:
10.4049/jimmunol.1103471. [PMID: 22786772] - Rodrigo Leite de Oliveira, Sofie Deschoemaeker, Anne-Theres Henze, Koen Debackere, Veronica Finisguerra, Yukiji Takeda, Carmen Roncal, Daniela Dettori, Evelyne Tack, Yannick Jönsson, Lorenzo Veschini, Annelies Peeters, Andrey Anisimov, Matthias Hofmann, Kari Alitalo, Myriam Baes, Jan D'hooge, Peter Carmeliet, Massimiliano Mazzone. Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Cancer cell.
2012 Aug; 22(2):263-77. doi:
10.1016/j.ccr.2012.06.028. [PMID: 22897855] - Xiaofang Yu, Yi Fang, Hong Liu, Jiaming Zhu, Jianzhou Zou, Xunhui Xu, Suhua Jiang, Xiaoqiang Ding. The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2012 Aug; 27(8):3110-9. doi:
10.1093/ndt/gfr754. [PMID: 22399494] - C Osorio, N Wen, R Gemini, R Zemetra, D von Wettstein, S Rustgi. Targeted modification of wheat grain protein to reduce the content of celiac causing epitopes.
Functional & integrative genomics.
2012 Aug; 12(3):417-38. doi:
10.1007/s10142-012-0287-y. [PMID: 22732824] - Sreenivasulu Chintala, Tanbir Najrana, Karoly Toth, Shousong Cao, Farukh A Durrani, Roberto Pili, Youcef M Rustum. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
BMC cancer.
2012 Jul; 12(?):293. doi:
10.1186/1471-2407-12-293. [PMID: 22804960] - Hui-Kyoung Sun, Yun Mi Lee, Kum Hyun Han, Han-Seong Kim, Seon-Ho Ahn, Sang-Youb Han. Phosphodiesterase inhibitor improves renal tubulointerstitial hypoxia of the diabetic rat kidney.
The Korean journal of internal medicine.
2012 Jun; 27(2):163-70. doi:
10.3904/kjim.2012.27.2.163. [PMID: 22707888] - Carol M Taylor, Chamini V Karunaratne, Ning Xie. Glycosides of hydroxyproline: some recent, unusual discoveries.
Glycobiology.
2012 Jun; 22(6):757-67. doi:
10.1093/glycob/cwr188. [PMID: 22190471] - Tetsuhiro Tanaka, Masaomi Nangaku. Recent advances and clinical application of erythropoietin and erythropoiesis-stimulating agents.
Experimental cell research.
2012 May; 318(9):1068-73. doi:
10.1016/j.yexcr.2012.02.035. [PMID: 22414872] - Pinelopi P Kapitsinou, Jonathan Jaffe, Mark Michael, Christina E Swan, Kevin J Duffy, Connie L Erickson-Miller, Volker H Haase. Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury.
American journal of physiology. Renal physiology.
2012 May; 302(9):F1172-9. doi:
10.1152/ajprenal.00667.2011. [PMID: 22262480] - Candida Vannini, Milena Marsoni, Carlo Cantara, Maria Concetta De Pinto, Vittoria Locato, Laura De Gara, Marcella Bracale. The soluble proteome of tobacco Bright Yellow-2 cells undergoing H₂O₂-induced programmed cell death.
Journal of experimental botany.
2012 May; 63(8):3137-55. doi:
10.1093/jxb/ers031. [PMID: 22355080] - Nadja Grobe, Khalid M Elased, David R Cool, Mariana Morris. Mass spectrometry for the molecular imaging of angiotensin metabolism in kidney.
American journal of physiology. Endocrinology and metabolism.
2012 Apr; 302(8):E1016-24. doi:
10.1152/ajpendo.00515.2011. [PMID: 22318946] - Urszula Szawłowska, Agnieszka Grabowska, Edyta Zdunek-Zastocka, Wiesław Bielawski. TsPAP1 encodes a novel plant prolyl aminopeptidase whose expression is induced in response to suboptimal growth conditions.
Biochemical and biophysical research communications.
2012 Mar; 419(1):104-9. doi:
10.1016/j.bbrc.2012.01.140. [PMID: 22330801] - Tetsuro Ishii, Eiji Warabi, Toru Yanagawa. Novel roles of peroxiredoxins in inflammation, cancer and innate immunity.
Journal of clinical biochemistry and nutrition.
2012 Mar; 50(2):91-105. doi:
10.3164/jcbn.11-109. [PMID: 22448089] - Zhendi Wang, Gunnar Schley, Gazi Türkoglu, Nicolai Burzlaff, Kerstin U Amann, Carsten Willam, Kai-Uwe Eckardt, Wanja M Bernhardt. The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2012 Mar; 27(3):929-36. doi:
10.1093/ndt/gfr379. [PMID: 21742784] - Iain C Macdougall. New anemia therapies: translating novel strategies from bench to bedside.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2012 Mar; 59(3):444-51. doi:
10.1053/j.ajkd.2011.11.013. [PMID: 22192713] - Jing-Yi Lin, Venugopal Mendu, Judit Pogany, Jun Qin, Peter D Nagy. The TPR domain in the host Cyp40-like cyclophilin binds to the viral replication protein and inhibits the assembly of the tombusviral replicase.
PLoS pathogens.
2012 Feb; 8(2):e1002491. doi:
10.1371/journal.ppat.1002491. [PMID: 22346747] - Mawadda Alnaeeli, Li Wang, Barbora Piknova, Heather Rogers, Xiaoxia Li, Constance Tom Noguchi. Erythropoietin in brain development and beyond.
Anatomy research international.
2012; 2012(?):953264. doi:
10.1155/2012/953264. [PMID: 22567318] - David S Domozych, Marina Ciancia, Jonatan U Fangel, Maria Dalgaard Mikkelsen, Peter Ulvskov, William G T Willats. The Cell Walls of Green Algae: A Journey through Evolution and Diversity.
Frontiers in plant science.
2012; 3(?):82. doi:
10.3389/fpls.2012.00082. [PMID: 22639667] - Chris Tikellis, M C Thomas. Angiotensin-Converting Enzyme 2 (ACE2) Is a Key Modulator of the Renin Angiotensin System in Health and Disease.
International journal of peptides.
2012; 2012(?):256294. doi:
10.1155/2012/256294. [PMID: 22536270] - Lucia Pastorino, Suk Ling Ma, Martin Balastik, Pengyu Huang, Darshan Pandya, Linda Nicholson, Kun Ping Lu. Alzheimer's disease-related loss of Pin1 function influences the intracellular localization and the processing of AβPP.
Journal of Alzheimer's disease : JAD.
2012; 30(2):277-97. doi:
10.3233/jad-2012-111259. [PMID: 22430533] - Gianpiero Vigani. Does a similar metabolic reprogramming occur in fe-deficient plant cells and animal tumor cells?.
Frontiers in plant science.
2012; 3(?):47. doi:
10.3389/fpls.2012.00047. [PMID: 22645588] - Takafumi Uchida, Kengo Furumai, Tomokazu Fukuda, Hirotada Akiyama, Mika Takezawa, Tomoichiro Asano, Fumihiro Fujimori, Chiyoko Uchida. Prolyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells.
PloS one.
2012; 7(3):e31823. doi:
10.1371/journal.pone.0031823. [PMID: 22412843] - Ruth E Schietke, Thomas Hackenbeck, Maxine Tran, Regina Günther, Bernd Klanke, Christina L Warnecke, Karl X Knaup, Deepa Shukla, Christian Rosenberger, Robert Koesters, Sebastian Bachmann, Peter Betz, Gunnar Schley, Johannes Schödel, Carsten Willam, Thomas Winkler, Kerstin Amann, Kai-Uwe Eckardt, Patrick Maxwell, Michael S Wiesener. Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts.
PloS one.
2012; 7(1):e31034. doi:
10.1371/journal.pone.0031034. [PMID: 22299048] - Shiyo Muratsu-Ikeda, Masaomi Nangaku, Yoichiro Ikeda, Tetsuhiro Tanaka, Takehiko Wada, Reiko Inagi. Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells.
PloS one.
2012; 7(7):e41462. doi:
10.1371/journal.pone.0041462. [PMID: 22859986] - Melina Velasquez, Juan Salgado Salter, Javier Gloazzo Dorosz, Bent L Petersen, José M Estevez. Recent Advances on the Posttranslational Modifications of EXTs and Their Roles in Plant Cell Walls.
Frontiers in plant science.
2012; 3(?):93. doi:
10.3389/fpls.2012.00093. [PMID: 22639676] - Dandan Han, Luan Wen, Yonglong Chen. Molecular cloning of phd1 and comparative analysis of phd1, 2, and 3 expression in Xenopus laevis.
TheScientificWorldJournal.
2012; 2012(?):689287. doi:
10.1100/2012/689287. [PMID: 22645445] - I Erdogan Orhan. Current concepts on selected plant secondary metabolites with promising inhibitory effects against enzymes linked to Alzheimer's disease.
Current medicinal chemistry.
2012; 19(14):2252-61. doi:
10.2174/092986712800229032. [PMID: 22414107] - Xiaofang Yu, Yi Fang, Xiaoqiang Ding, Hong Liu, Jiaming Zhu, Jianzhou Zou, Xunhui Xu, Yihong Zhong. Transient hypoxia-inducible factor activation in rat renal ablation and reduced fibrosis with L-mimosine.
Nephrology (Carlton, Vic.).
2012 Jan; 17(1):58-67. doi:
10.1111/j.1440-1797.2011.01498.x. [PMID: 21777345] - Dominador J Manalo, Jin Hyen Baek, Paul W Buehler, Evi Struble, Bindu Abraham, Abdu I Alayash. Inactivation of prolyl hydroxylase domain (PHD) protein by epigallocatechin (EGCG) stabilizes hypoxia-inducible factor (HIF-1α) and induces hepcidin (Hamp) in rat kidney.
Biochemical and biophysical research communications.
2011 Dec; 416(3-4):421-6. doi:
10.1016/j.bbrc.2011.11.085. [PMID: 22138393] - Biao Yan, Zhaoxia Huo, Ying Liu, Xiaoping Lin, Jun Li, Luying Peng, Hong Zhao, Zhao-Nian Zhou, Xingqun Liang, Yi Liu, Weidong Zhu, Dandan Liang, Li Li, Yunfu Sun, Jianmin Cui, Yi-Han Chen. Prolyl hydroxylase 2: a novel regulator of β2 -adrenoceptor internalization.
Journal of cellular and molecular medicine.
2011 Dec; 15(12):2712-22. doi:
10.1111/j.1582-4934.2011.01268.x. [PMID: 21255264] - Xiao-Li Zhang, Zhen-Wen Yan, Wei-Wen Sheng, Jing Xiao, Zhen-Xing Zhang, Zhi-Bin Ye. Activation of hypoxia-inducible factor-1 ameliorates postischemic renal injury via inducible nitric oxide synthase.
Molecular and cellular biochemistry.
2011 Dec; 358(1-2):287-95. doi:
10.1007/s11010-011-0979-y. [PMID: 21755458] - Anjali Nandal, Julio C Ruiz, Poorna Subramanian, Sudipa Ghimire-Rijal, Ruth Ann Sinnamon, Timothy L Stemmler, Richard K Bruick, Caroline C Philpott. Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2.
Cell metabolism.
2011 Nov; 14(5):647-57. doi:
10.1016/j.cmet.2011.08.015. [PMID: 22055506] - Julie Adam, Peter J Ratcliffe, Patrick J Pollard. Novel insights into FH-associated disease are KEAPing the lid on oncogenic HIF signalling.
Oncotarget.
2011 Nov; 2(11):820-1. doi:
10.18632/oncotarget.348. [PMID: 22064867] - Xiling Zou, Yuanyuan Jiang, Yonglian Zheng, Meidong Zhang, Zuxin Zhang. Prolyl 4-hydroxylase genes are subjected to alternative splicing in roots of maize seedlings under waterlogging.
Annals of botany.
2011 Nov; 108(7):1323-35. doi:
10.1093/aob/mcr223. [PMID: 21969257] - Urszula Szawłowska, Edyta Zdunek-Zastocka, Wiesław Bielawski. Biochemical characterisation of prolyl aminopeptidase from shoots of triticale seedlings and its activity changes in response to suboptimal growth conditions.
Plant physiology and biochemistry : PPB.
2011 Nov; 49(11):1342-9. doi:
10.1016/j.plaphy.2011.05.008. [PMID: 21689943] - Julie Adam, Emine Hatipoglu, Linda O'Flaherty, Nicola Ternette, Natasha Sahgal, Helen Lockstone, Dilair Baban, Emma Nye, Gordon W Stamp, Kathryn Wolhuter, Marcus Stevens, Roman Fischer, Peter Carmeliet, Patrick H Maxwell, Chris W Pugh, Norma Frizzell, Tomoyoshi Soga, Benedikt M Kessler, Mona El-Bahrawy, Peter J Ratcliffe, Patrick J Pollard. Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Cancer cell.
2011 Oct; 20(4):524-37. doi:
10.1016/j.ccr.2011.09.006. [PMID: 22014577] - Sheetal Gandotra, Koini Lim, Amandine Girousse, Vladimir Saudek, Stephen O'Rahilly, David B Savage. Human frame shift mutations affecting the carboxyl terminus of perilipin increase lipolysis by failing to sequester the adipose triglyceride lipase (ATGL) coactivator AB-hydrolase-containing 5 (ABHD5).
The Journal of biological chemistry.
2011 Oct; 286(40):34998-5006. doi:
10.1074/jbc.m111.278853. [PMID: 21757733] - Silvia M Velasquez, Norberto D Iusem, José M Estevez. Root hair sweet growth.
Plant signaling & behavior.
2011 Oct; 6(10):1600-2. doi:
10.4161/psb.6.10.17135. [PMID: 21918376] - Brian L Teng, Kathryn E Hacker, Shufen Chen, Anthony R Means, W Kimryn Rathmell. Tumor suppressive activity of prolyl isomerase Pin1 in renal cell carcinoma.
Molecular oncology.
2011 Oct; 5(5):465-74. doi:
10.1016/j.molonc.2011.06.002. [PMID: 21764651] - Simone Patergnani, Jan M Suski, Chiara Agnoletto, Angela Bononi, Massimo Bonora, Elena De Marchi, Carlotta Giorgi, Saverio Marchi, Sonia Missiroli, Federica Poletti, Alessandro Rimessi, Jerzy Duszynski, Mariusz R Wieckowski, Paolo Pinton. Calcium signaling around Mitochondria Associated Membranes (MAMs).
Cell communication and signaling : CCS.
2011 Sep; 9(?):19. doi:
10.1186/1478-811x-9-19. [PMID: 21939514] - Maret G Traber, Jan F Stevens. Vitamins C and E: beneficial effects from a mechanistic perspective.
Free radical biology & medicine.
2011 Sep; 51(5):1000-13. doi:
10.1016/j.freeradbiomed.2011.05.017. [PMID: 21664268] - Ching-Ti Liu, Maija K Garnaas, Adrienne Tin, Anna Kottgen, Nora Franceschini, Carmen A Peralta, Ian H de Boer, Xiaoning Lu, Elizabeth Atkinson, Jingzhong Ding, Michael Nalls, Daniel Shriner, Josef Coresh, Abdullah Kutlar, Kirsten Bibbins-Domingo, David Siscovick, Ermeg Akylbekova, Sharon Wyatt, Brad Astor, Josef Mychaleckjy, Man Li, Muredach P Reilly, Raymond R Townsend, Adebowale Adeyemo, Alan B Zonderman, Mariza de Andrade, Stephen T Turner, Thomas H Mosley, Tamara B Harris, Charles N Rotimi, Yongmei Liu, Sharon L R Kardia, Michele K Evans, Michael G Shlipak, Holly Kramer, Michael F Flessner, Albert W Dreisbach, Wolfram Goessling, L Adrienne Cupples, W Linda Kao, Caroline S Fox. Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
PLoS genetics.
2011 Sep; 7(9):e1002264. doi:
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Journal of neuroinflammation.
2011 Jul; 8(?):86. doi:
10.1186/1742-2094-8-86. [PMID: 21801384] - Anna Stachurska, Magdalena Kozakowska, Alicja Jozkowicz, Jozef Dulak, Agnieszka Loboda. Aristolochic acid I and ochratoxin A differentially regulate VEGF expression in porcine kidney epithelial cells--the involvement of SP-1 and HIFs transcription factors.
Toxicology letters.
2011 Jul; 204(2-3):118-26. doi:
10.1016/j.toxlet.2011.04.022. [PMID: 21554934] - Sarah K Harten, Miguel A Esteban, Deepa Shukla, Margaret Ashcroft, Patrick H Maxwell. Inactivation of the von Hippel-Lindau tumour suppressor gene induces Neuromedin U expression in renal cancer cells.
Molecular cancer.
2011 Jul; 10(?):89. doi:
10.1186/1476-4598-10-89. [PMID: 21791076] - John P Délano-Frier, Hamlet Avilés-Arnaut, Kena Casarrubias-Castillo, Gabriela Casique-Arroyo, Paula A Castrillón-Arbeláez, Luis Herrera-Estrella, Julio Massange-Sánchez, Norma A Martínez-Gallardo, Fannie I Parra-Cota, Erandi Vargas-Ortiz, María G Estrada-Hernández. Transcriptomic analysis of grain amaranth (Amaranthus hypochondriacus) using 454 pyrosequencing: comparison with A. tuberculatus, expression profiling in stems and in response to biotic and abiotic stress.
BMC genomics.
2011 Jul; 12(?):363. doi:
10.1186/1471-2164-12-363. [PMID: 21752295] - Mareike Ströfer, Wolfgang Jelkmann, Reinhard Depping. Curcumin decreases survival of Hep3B liver and MCF-7 breast cancer cells: the role of HIF.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al].
2011 Jul; 187(7):393-400. doi:
10.1007/s00066-011-2248-0. [PMID: 21713389] - Sabine Leh, Michael Hultström, Christian Rosenberger, Bjarne M Iversen. Afferent arteriolopathy and glomerular collapse but not segmental sclerosis induce tubular atrophy in old spontaneously hypertensive rats.
Virchows Archiv : an international journal of pathology.
2011 Jul; 459(1):99-108. doi:
10.1007/s00428-011-1100-3. [PMID: 21660521] - Li Wang, Lili Zhang, Yunfeng Geng, Wei Xi, Rongxiang Fang, Yantao Jia. XerR, a negative regulator of XccR in Xanthomonas campestris pv. campestris, relieves its repressor function in planta.
Cell research.
2011 Jul; 21(7):1131-42. doi:
10.1038/cr.2011.64. [PMID: 21483448] - Xing Xu, Qinglei Gan, Richard C Clough, Kameshwari M Pappu, John A Howard, Julio A Baez, Kan Wang. Hydroxylation of recombinant human collagen type I alpha 1 in transgenic maize co-expressed with a recombinant human prolyl 4-hydroxylase.
BMC biotechnology.
2011 Jun; 11(?):69. doi:
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Science (New York, N.Y.).
2011 Jun; 332(6036):1401-3. doi:
10.1126/science.1206657. [PMID: 21680836] - B P Mallikarjuna Swamy, Prashant Vikram, Shalabh Dixit, H U Ahmed, Arvind Kumar. Meta-analysis of grain yield QTL identified during agricultural drought in grasses showed consensus.
BMC genomics.
2011 Jun; 12(?):319. doi:
10.1186/1471-2164-12-319. [PMID: 21679437] - Poyil Pratheeshkumar, Girija Kuttan. Vernonia cinerea Less. inhibits tumor cell invasion and pulmonary metastasis in C57BL/6 mice.
Integrative cancer therapies.
2011 Jun; 10(2):178-91. doi:
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The Plant cell.
2011 Apr; 23(4):1273-92. doi:
10.1105/tpc.111.084400. [PMID: 21498682] - J R Chapman. Chronic calcineurin inhibitor nephrotoxicity-lest we forget.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
2011 Apr; 11(4):693-7. doi:
10.1111/j.1600-6143.2011.03504.x. [PMID: 21446974] - Jin Hyen Baek, Chad E N Reiter, Dominador J Manalo, Paul W Buehler, Robert C Hider, Abdu I Alayash. Induction of hypoxia inducible factor (HIF-1α) in rat kidneys by iron chelation with the hydroxypyridinone, CP94.
Biochimica et biophysica acta.
2011 Apr; 1809(4-6):262-8. doi:
10.1016/j.bbagrm.2011.04.010. [PMID: 21558026] - Mandi Wiley, Crystal Teygong, Eric Phelps, Jay Radke, Ira J Blader. Serum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells.
PloS one.
2011 Mar; 6(3):e18335. doi:
10.1371/journal.pone.0018335. [PMID: 21479245] - M N Khan, T Bhattacharyya, P Andrikopoulos, M A Esteban, R Barod, T Connor, M Ashcroft, P H Maxwell, S Kiriakidis. Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis.
British journal of cancer.
2011 Mar; 104(7):1151-9. doi:
10.1038/bjc.2011.73. [PMID: 21386837] - Wolfgang Jelkmann. Regulation of erythropoietin production.
The Journal of physiology.
2011 Mar; 589(Pt 6):1251-8. doi:
10.1113/jphysiol.2010.195057. [PMID: 21078592] - Jian Wang, Kostas Pantopoulos. Regulation of cellular iron metabolism.
The Biochemical journal.
2011 Mar; 434(3):365-81. doi:
10.1042/bj20101825. [PMID: 21348856] - Volkan Yıldırım, Servet Ozcan, Dörte Becher, Knut Büttner, Michael Hecker, Gülay Ozcengiz. Characterization of proteome alterations in Phanerochaete chrysosporium in response to lead exposure.
Proteome science.
2011 Mar; 9(?):12. doi:
10.1186/1477-5956-9-12. [PMID: 21388532] - Jennifer Schoberer, Richard Strasser. Sub-compartmental organization of Golgi-resident N-glycan processing enzymes in plants.
Molecular plant.
2011 Mar; 4(2):220-8. doi:
10.1093/mp/ssq082. [PMID: 21307368] - Yumi Takiyama, Tatsuo Harumi, Jun Watanabe, Yukihiro Fujita, Jun Honjo, Norihiko Shimizu, Yuichi Makino, Masakazu Haneda. Tubular injury in a rat model of type 2 diabetes is prevented by metformin: a possible role of HIF-1α expression and oxygen metabolism.
Diabetes.
2011 Mar; 60(3):981-92. doi:
10.2337/db10-0655. [PMID: 21282369] - Chunxiang Xu, Tomáš Takáč, Christian Burbach, Diedrik Menzel, Jozef Samaj. Developmental localization and the role of hydroxyproline rich glycoproteins during somatic embryogenesis of banana (Musa spp. AAA).
BMC plant biology.
2011 Feb; 11(?):38. doi:
10.1186/1471-2229-11-38. [PMID: 21349190] - Tingsu Chen, Karolina Hoffmann, Sofia Ostman, Ann-Sofie Sandberg, Olof Olsson. Identification of gliadin-binding peptides by phage display.
BMC biotechnology.
2011 Feb; 11(?):16. doi:
10.1186/1472-6750-11-16. [PMID: 21329494] - Raj Munshi, Christine Hsu, Jonathan Himmelfarb. Advances in understanding ischemic acute kidney injury.
BMC medicine.
2011 Feb; 9(?):11. doi:
10.1186/1741-7015-9-11. [PMID: 21288330] - Shinsaku Togo, Tadashi Sato, Hisatoshi Sugiura, Xingqi Wang, Hesham Basma, Amy Nelson, Xiangde Liu, Tom W Bargar, John G Sharp, Stephen I Rennard. Differentiation of embryonic stem cells into fibroblast-like cells in three-dimensional type I collagen gel cultures.
In vitro cellular & developmental biology. Animal.
2011 Feb; 47(2):114-24. doi:
10.1007/s11626-010-9367-2. [PMID: 21107747] - Virgínia L F Soares, Simone M Rodrigues, Tahise M de Oliveira, Talisson O de Queiroz, Lívia S Lima, Braz T Hora-Júnior, Karina P Gramacho, Fabienne Micheli, Júlio C M Cascardo, Wagner C Otoni, Abelmon S Gesteira, Marcio G C Costa. Unraveling new genes associated with seed development and metabolism in Bixa orellana L. by expressed sequence tag (EST) analysis.
Molecular biology reports.
2011 Feb; 38(2):1329-40. doi:
10.1007/s11033-010-0234-8. [PMID: 20563648] - Toshio Miyata, Shunya Takizawa, Charles van Ypersele de Strihou. Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets.
American journal of physiology. Cell physiology.
2011 Feb; 300(2):C226-31. doi:
10.1152/ajpcell.00430.2010. [PMID: 20980551] - Dewi Astuti, Christopher J Ricketts, Rasheduzzaman Chowdhury, Michael A McDonough, Dean Gentle, Gail Kirby, Susanne Schlisio, Rajappa S Kenchappa, Bruce D Carter, William G Kaelin, Peter J Ratcliffe, Christopher J Schofield, Farida Latif, Eamonn R Maher. Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility.
Endocrine-related cancer.
2011 Feb; 18(1):73-83. doi:
10.1677/erc-10-0113. [PMID: 20959442] - Ian M Ahearn, Frederick D Tsai, Helen Court, Mo Zhou, Benjamin C Jennings, Mahiuddin Ahmed, Nicole Fehrenbacher, Maurine E Linder, Mark R Philips. FKBP12 binds to acylated H-ras and promotes depalmitoylation.
Molecular cell.
2011 Jan; 41(2):173-85. doi:
10.1016/j.molcel.2011.01.001. [PMID: 21255728] - Erika Bourseau-Guilmain, Audrey Griveau, Jean-Pierre Benoit, Emmanuel Garcion. The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells.
PloS one.
2011; 6(9):e25515. doi:
10.1371/journal.pone.0025515. [PMID: 21966538] - Joel I Perez-Perri, Julieta M Acevedo, Pablo Wappner. Epigenetics: new questions on the response to hypoxia.
International journal of molecular sciences.
2011; 12(7):4705-21. doi:
10.3390/ijms12074705. [PMID: 21845106] - Christo Venkov, David Plieth, Terri Ni, Amitava Karmaker, Aihua Bian, Alfred L George, Eric G Neilson. Transcriptional networks in epithelial-mesenchymal transition.
PloS one.
2011; 6(9):e25354. doi:
10.1371/journal.pone.0025354. [PMID: 21980432] - Tomoharu Tanaka, Shinichi Kai, Tomohiro Koyama, Hiroki Daijo, Takehiko Adachi, Kazuhiko Fukuda, Kiichi Hirota. General anesthetics inhibit erythropoietin induction under hypoxic conditions in the mouse brain.
PloS one.
2011; 6(12):e29378. doi:
10.1371/journal.pone.0029378. [PMID: 22216265] - Yoshikatsu Matsubayashi. Post-translational modifications in secreted peptide hormones in plants.
Plant & cell physiology.
2011 Jan; 52(1):5-13. doi:
10.1093/pcp/pcq169. [PMID: 21071428] - Glen W Barrisford, Eric A Singer, Inger L Rosner, W Marston Linehan, Gennady Bratslavsky. Familial renal cancer: molecular genetics and surgical management.
International journal of surgical oncology.
2011; 2011(?):658767. doi:
10.1155/2011/658767. [PMID: 22312516] - Robert N Foley. Treatment of anemia in chronic kidney disease: known, unknown, and both.
Journal of blood medicine.
2011; 2(?):103-12. doi:
10.2147/jbm.s13066. [PMID: 22287869] - Hiroshi Oka, Hirozo Goto, Keiichi Koizumi, Shin Nakamura, Koichi Tsuneyama, Yue Zhou, Michiko Jo, Takako Fujimoto, Hiroaki Sakurai, Naotoshi Shibahara, Ikuo Saiki, Yutaka Shimada. Effect of Hachimijiogan against Renal Dysfunction and Involvement of Hypoxia-Inducible Factor-1α in the Remnant Kidney Model.
Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):348686. doi:
10.1155/2011/348686. [PMID: 21423692] - Brendan O'Leary, Srinath K Rao, William C Plaxton. Phosphorylation of bacterial-type phosphoenolpyruvate carboxylase at Ser425 provides a further tier of enzyme control in developing castor oil seeds.
The Biochemical journal.
2011 Jan; 433(1):65-74. doi:
10.1042/bj20101361. [PMID: 20950272] - Liang Zhou, Haifeng Yang. The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.
PloS one.
2011; 6(9):e23936. doi:
10.1371/journal.pone.0023936. [PMID: 21949687] - Ryo Moriguchi, Chiaya Matsuoka, Akiko Suyama, Ken Matsuoka. Reduction of plant-specific arabinogalactan-type O-glycosylation by treating tobacco plants with ferrous chelator 2,2'-dipyridyl.
Bioscience, biotechnology, and biochemistry.
2011; 75(5):994-6. doi:
10.1271/bbb.100884. [PMID: 21597170] - Holger Scholz, Karin M Kirschner. Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms' Tumor Gene, WT1.
Frontiers in molecular neuroscience.
2011; 4(?):4. doi:
10.3389/fnmol.2011.00004. [PMID: 21430823] - Xiaoqing Pan, Norio Suzuki, Ikuo Hirano, Shun Yamazaki, Naoko Minegishi, Masayuki Yamamoto. Isolation and characterization of renal erythropoietin-producing cells from genetically produced anemia mice.
PloS one.
2011; 6(10):e25839. doi:
10.1371/journal.pone.0025839. [PMID: 22022454] - Irene Abreu-Rodríguez, Rocío Sánchez Silva, Ana Paula Martins, Graça Soveral, Juan José Toledo-Aral, José López-Barneo, Miriam Echevarría. Functional and transcriptional induction of aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α.
PloS one.
2011; 6(12):e28385. doi:
10.1371/journal.pone.0028385. [PMID: 22174795] - Sunil Sudarshan, Karthigayan Shanmugasundaram, Susan L Naylor, Shu Lin, Carolina B Livi, Christine F O'Neill, Dipen J Parekh, I-Tien Yeh, Lu-Zhe Sun, Karen Block. Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion.
PloS one.
2011; 6(6):e21037. doi:
10.1371/journal.pone.0021037. [PMID: 21695080] - Ajith Vengellur, Elizabeth Grier, John J Lapres. The Loss of HIF1α Leads to Increased Susceptibility to Cadmium-Chloride-Induced Toxicity in Mouse Embryonic Fibroblasts.
Journal of toxicology.
2011; 2011(?):391074. doi:
10.1155/2011/391074. [PMID: 21811500] - Jaana Hyvärinen, Mataleena Parikka, Raija Sormunen, Mika Rämet, Karl Tryggvason, Kari I Kivirikko, Johanna Myllyharju, Peppi Koivunen. Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function.
The Journal of biological chemistry.
2010 Dec; 285(53):42023-32. doi:
10.1074/jbc.m110.145904. [PMID: 20952382] - Wayne Chadwick, Randall Brenneman, Bronwen Martin, Stuart Maudsley. Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease.
International journal of Alzheimer's disease.
2010 Dec; 2010(?):604792. doi:
10.4061/2010/604792. [PMID: 21151659] - Wanja M Bernhardt, Michael S Wiesener, Paul Scigalla, James Chou, Roland E Schmieder, Volkmar Günzler, Kai-Uwe Eckardt. Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.
Journal of the American Society of Nephrology : JASN.
2010 Dec; 21(12):2151-6. doi:
10.1681/asn.2010010116. [PMID: 21115615]