clidinium bromide (BioDeep_00000750160)

   


代谢物信息卡片


clidinium bromide

化学式: C22H26BrNO3 (431.10959460000004)
中文名称: 克利溴铵
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C[N+]1(CC2)CC(OC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=O)C2CC1.[Br-]
InChI: /p-1

描述信息

C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics
C78272 - Agent Affecting Nervous System > C29698 - Antispasmodic Agent
Clidinium bromide is a quaternary amine antimuscarinic agent. Clidinium bromide may help symptoms of cramping and abdominal/stomach pain by decreasing stomach acid, and slowing the intestines in vivo[1].

同义名列表

3 个代谢物同义名

clidinium bromide; Ro 2-3773; Clidinium (bromide)



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Sapna Lonare, Monica Sharma, Vikram Dalal, Mrugendra Gubyad, Pranav Kumar, Deena Nath Gupta, Akshay Pareek, Shailly Tomar, Dilip Kumar Ghosh, Pravindra Kumar, Ashwani Kumar Sharma. Identification and evaluation of potential inhibitor molecules against TcyA from Candidatus Liberibacter asiaticus. Journal of structural biology. 2023 Jun; 215(3):107992. doi: 10.1016/j.jsb.2023.107992. [PMID: 37394197]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • T Iriuchijima, T Michimata, H Mizuma, M Murakami, M Yamada, M Mori. Hypothyroidism inhibits the formation of inositol phosphate in response to carbachol in the striatum of adult rat. Research communications in chemical pathology and pharmacology. 1991 Aug; 73(2):173-80. doi: . [PMID: 1784833]
  • C A Otto, G K Mulholland, S B DeMattos, P S Sherman, T L Pisani, G Hingorani. Evaluation of quaternized and neutral muscarinic receptor ligands in normal and DES-treated rat. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 1991; 18(5):557-61. doi: 10.1016/0883-2897(91)90118-5. [PMID: 1917526]
  • J H Turner, M Maziere, D Comar. Localization of 11C-radiopharmaceuticals in the Greene melanoma of hamsters. European journal of nuclear medicine. 1985; 10(9-10):392-7. doi: 10.1007/bf00256577. [PMID: 3159576]
  • R E Gibson, W C Eckelman, F Vieras, R C Reba. The distribution of the muscarinic acetylcholine receptor antagonists, quinuclidinyl benzilate and quinuclidinyl benzilate methiodide (both tritiated), in rat, guinea pig, and rabbit. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1979 Aug; 20(8):865-70. doi: NULL. [PMID: 541735]