Urofollitropin (BioDeep_00000749755)
代谢物信息卡片
化学式: C42H65N11O12S2 (979.4255370000001)
中文名称: 4-(L-苏氨酸)缩宫素, 尿促卵泡素, 卵泡刺激素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)C(C)O
InChI: InChI=1S/C42H65N11O12S2/c1-6-21(4)33-40(63)52-34(22(5)54)41(64)49-28(16-31(44)56)37(60)50-29(19-67-66-18-25(43)35(58)47-27(38(61)51-33)15-23-9-11-24(55)12-10-23)42(65)53-13-7-8-30(53)39(62)48-26(14-20(2)3)36(59)46-17-32(45)57/h9-12,20-22,25-30,33-34,54-55H,6-8,13-19,43H2,1-5H3,(H2,44,56)(H2,45,57)(H,46,59)(H,47,58)(H,48,62)(H,49,64)(H,50,60)(H,51,61)(H,52,63)
描述信息
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03G - Gonadotropins and other ovulation stimulants > G03GA - Gonadotropins
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
2 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Valentina Notarstefano, Giorgia Gioacchini, Elisabetta Giorgini, Nina Montik, Andrea Ciavattini, Anna Rita Polidori, Fulvia Antonia Candela, Lisa Vaccari, Maurizio Cignitti, Oliana Carnevali. The Impact of Controlled Ovarian Stimulation Hormones on the Metabolic State and Endocannabinoid System of Human Cumulus Cells.
International journal of molecular sciences.
2020 Sep; 21(19):. doi:
10.3390/ijms21197124. [PMID: 32992491] - Sandro La Vignera, Rosita A Condorelli, Rossella Cannarella, Laura Cimino, Laura Mongioi', Ylenia Duca, Filippo Giacone, Aldo E Calogero. Testosterone levels after treatment with urofollitropin in infertile patients with idiopathic mild reduction of testicular volume.
Endocrine.
2019 11; 66(2):381-385. doi:
10.1007/s12020-019-01983-0. [PMID: 31240459] - Andrea Cocci, Gianmartin Cito, Giorgio I Russo, Marco Falcone, Marco Capece, Massimiliano Timpano, Pier Andrea Della Camera, Simone Morselli, Giovanni Tasso, Girolamo Morelli, Giuseppe Morgia, Andrea Minervini, Sergio Serni, Marco Carini, Alessandro Natali, Mauro Gacci. Effectiveness of highly purified urofollitropin treatment in patients with idiopathic azoospermia before testicular sperm extraction.
Urologia.
2018 Feb; 85(1):19-21. doi:
10.5301/uj.5000253. [PMID: 28799634] - Priya Bhide, Åse Vårtun, Berit Aune, Kari Flo, Purusotam Basnet, Ganesh Acharya. Ovarian reserve in women with a previous history of severe pre-eclampsia.
Archives of gynecology and obstetrics.
2017 Jan; 295(1):233-238. doi:
10.1007/s00404-016-4193-8. [PMID: 27604242] - Michael V Gavalas, Alexander Breskin, Melana Yuzefpolskaya, Andrew Eisenberger, Francesco Castagna, Ryan T Demmer, Margaret Flannery, A Reshad Garan, Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Veli K Topkara, Paolo C Colombo. Discriminatory performance of positive urine hemoglobin for detection of significant hemolysis in patients with continuous-flow left ventricular assist devices.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
2017 01; 36(1):59-63. doi:
10.1016/j.healun.2016.08.026. [PMID: 27773451] - Andrea F D Di Stefano, Antonio Rusca, Milko M Radicioni, Luca Loprete, Daniela Binelli, Giorgio Caccia, Barbara Cometti. Pharmacokinetics and Pharmacodynamics of Follicle-Stimulating Hormone in Healthy Women Receiving Single and Multiple Doses of Highly Purified Human Menotrophin and Urofollitrophin.
Clinical drug investigation.
2016 Dec; 36(12):1031-1044. doi:
10.1007/s40261-016-0451-6. [PMID: 27638053] - Manna Zhang, Guoyu Tong, Yanling Liu, Yiming Mu, Jianping Weng, Yaoming Xue, Zuojie Luo, Yuanming Xue, Lixin Shi, Xueyan Wu, Shouyue Sun, Yanhua Zhu, Ying Cao, Jie Zhang, Hong Huang, Ben Niu, Hong Li, Qinghua Guo, Yan Gao, Zhibin Li, Guang Ning, Dalong Zhu, Xiaoying Li. Sequential Versus Continual Purified Urinary FSH/hCG in Men With Idiopathic Hypogonadotropic Hypogonadism.
The Journal of clinical endocrinology and metabolism.
2015 Jun; 100(6):2449-55. doi:
10.1210/jc.2014-3802. [PMID: 25825944] - Yoshimitsu Kuwabara, Katsuya Mine, Akira Katayama, Tomoko Inagawa, Shigeo Akira, Toshiyuki Takeshita. Proteomic analyses of recombinant human follicle-stimulating hormone and urinary-derived gonadotropin preparations.
The Journal of reproductive medicine.
2009 Aug; 54(8):459-66. doi:
NULL. [PMID: 19769189] - Pornanong Aramwit, Kamthorn Pruksananonda, Narat Kasettratat, Karnphat Jammeechai. Risk factors for ovarian hyperstimulation syndrome in Thai patients using gonadotropins for in vitro fertilization.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
2008 Jun; 65(12):1148-53. doi:
10.2146/ajhp070566. [PMID: 18541685] - M Lispi, R Bassett, C Crisci, M Mancinelli, F Martelli, D Ceccarelli, C De Bellis, D Mendola. Comparative assessment of the consistency and quality of a highly purified FSH extracted from human urine (urofollitropin) and a recombinant human FSH (follitropin alpha).
Reproductive biomedicine online.
2006 Aug; 13(2):179-93. doi:
10.1016/s1472-6483(10)60613-x. [PMID: 16895630]