Tutin (BioDeep_00000007465)

   

natural product PANOMIX_OTCML-2023 Volatile Flavor Compounds


代谢物信息卡片


Tutin

化学式: C15H18O6 (294.11033280000004)
中文名称: 羟基马桑毒内酯
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 9.09%

分子结构信息

SMILES: C=C(C)C1C2OC(=O)C1C1(O)C3OC3C3(CO3)C1(C)C2O
InChI: InChI=1S/C15H18O6/c1-5(2)6-7-12(17)20-8(6)9(16)13(3)14(4-19-14)10-11(21-10)15(7,13)18/h6-11,16,18H,1,4H2,2-3H3/t6-,7+,8+,9+,10+,11-,13-,14+,15-/m0/s1

描述信息

同义名列表

2 个代谢物同义名

Tutin; Tutin



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Feifei Li, Jun Cui, Tayyab Shaheen, Guanghui Tang, Tao Wang, Tracy Woolfley, Menglou Li. Biocidal efficacy of tutin and its influence on immune cells and expression of growth-blocking and neuroglian peptides in Mythimna separata (Lepidoptera: Noctuidae). Archives of insect biochemistry and physiology. 2021 May; 107(1):e21767. doi: 10.1002/arch.21767. [PMID: 33835527]
  • Florent Olivon, Pascal Retailleau, Sandy Desrat, David Touboul, Fanny Roussi, Cécile Apel, Marc Litaudon. Isolation of Picrotoxanes from Austrobuxus carunculatus Using Taxonomy-Based Molecular Networking. Journal of natural products. 2020 10; 83(10):3069-3079. doi: 10.1021/acs.jnatprod.0c00636. [PMID: 33016067]
  • Oliver C Watkins, Nigel I Joyce, Nick Gould, Nigel B Perry. Glycosides of the Neurotoxin Tutin in Toxic Honeys Are from Coriaria arborea Phloem Sap, Not Insect Metabolism. Journal of natural products. 2018 04; 81(4):1116-1120. doi: 10.1021/acs.jnatprod.8b00120. [PMID: 29504746]
  • Michael Beasley, Dell Hood, Philippa Anderson, John Reeve, Robin J Slaughter. Poisoning due to tutin in honey-a report of an outbreak in New Zealand. The New Zealand medical journal. 2018 04; 131(1473):59-71. doi: . [PMID: 29649198]
  • Lesley Larsen, Nigel I Joyce, Catherine E Sansom, Janine M Cooney, Dwayne J Jensen, Nigel B Perry. Sweet Poisons: Honeys Contaminated with Glycosides of the Neurotoxin Tutin. Journal of natural products. 2015 Jun; 78(6):1363-9. doi: 10.1021/acs.jnatprod.5b00241. [PMID: 25993882]
  • Barry A Fields, John Reeve, Andrew Bartholomaeus, Utz Mueller. Human pharmacokinetic study of tutin in honey; a plant-derived neurotoxin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2014 Oct; 72(?):234-41. doi: 10.1016/j.fct.2014.07.032. [PMID: 25084484]
  • Soheil Zorofchian Moghadamtousi, Muhamad Noor Alfarizal Kamarudin, Chim Kei Chan, Bey Hing Goh, Habsah Abdul Kadir. Phytochemistry and biology of Loranthus parasiticus Merr, a commonly used herbal medicine. The American journal of Chinese medicine. 2014; 42(1):23-35. doi: 10.1142/s0192415x14500025. [PMID: 24467533]
  • Sally F Belcher, Tom R Morton. Tutu toxicity: three case reports of Coriaria arborea ingestion, review of literature and recommendations for management. The New Zealand medical journal. 2013 Mar; 126(1370):103-9. doi: ". [PMID: 23474518]
  • Jorge Fuentealba, Braulio Muñoz, Gonzalo Yévenes, Gustavo Moraga-Cid, Claudia Pérez, Leonardo Guzmán, Jean Michel Rigo, Luis G Aguayo. Potentiation and inhibition of glycine receptors by tutin. Neuropharmacology. 2011 Feb; 60(2-3):453-9. doi: 10.1016/j.neuropharm.2010.10.023. [PMID: 21044637]
  • Jorge Fuentealba, Leonardo Guzmán, Paula Manríquez-Navarro, Claudia Pérez, Mario Silva, José Becerra, Luis G Aguayo. Inhibitory effects of tutin on glycine receptors in spinal neurons. European journal of pharmacology. 2007 Mar; 559(1):61-4. doi: 10.1016/j.ejphar.2006.12.018. [PMID: 17303114]
  • Hua Zhou, Yu Zheng, Yu-Hong Tang. [Tutin-induced epileptiform discharge of CA1 pyramidal cells in rat hippocampal slices]. Sheng li xue bao : [Acta physiologica Sinica]. 2004 Jun; 56(3):341-6. doi: . [PMID: 15224147]