Benzofurazan (BioDeep_00000745450)
Volatile Flavor Compounds
代谢物信息卡片
2,1,3-benzoxadiazole
化学式: C6H4N2O (120.0323614)
中文名称: 依托唑灵, 苯并呋咱
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC2=NON=C2C=C1
InChI: InChI=1S/C6H4N2O/c1-2-4-6-5(3-1)7-9-8-6/h1-4H
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ebtehal F Anwer, Deena A M Nour El-Deen, Sayed M Derayea, Mahmoud A Omar. Benzofurazan -based fluorophore for the spectrofluorimetric determination of 6-Aminocaproic acid: Application to spiked human plasma and urine.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Mar; 268(?):120723. doi:
10.1016/j.saa.2021.120723. [PMID: 34915229] - Mahmoud A Omar, Hytham M Ahmed, Hany A Batakoushy, Mohamed A Abdel Hamid. New spectrofluorimetric analysis of empagliflozin in its tablets and human plasma using two level full factorial design.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Jul; 235(?):118307. doi:
10.1016/j.saa.2020.118307. [PMID: 32247255] - Samiha A Hussein, Baher I Salman, Marwa F B Ali, Mostafa A Marzouq. Development of sensitive benzofurazan-based spectrometric methods for analysis of spectinomycin in vials and human biological samples.
Luminescence : the journal of biological and chemical luminescence.
2019 Dec; 34(8):895-902. doi:
10.1002/bio.3688. [PMID: 31379072] - Baher I Salman, Marwa F B Ali, Mostafa A Marzouq, Samiha A Hussein. Utility of the fluorogenic characters of benzofurazan for analysis of tigecycline using spectrometric technique; application to pharmacokinetic study, urine and pharmaceutical formulations.
Luminescence : the journal of biological and chemical luminescence.
2019 Mar; 34(2):175-182. doi:
10.1002/bio.3590. [PMID: 30637925] - Shenggang Wang, Huihui Yin, Yue Huang, Xiangming Guan. Thiol Specific and Mitochondria Selective Fluorogenic Benzofurazan Sulfide for Live Cell Nonprotein Thiol Imaging and Quantification in Mitochondria.
Analytical chemistry.
2018 07; 90(13):8170-8177. doi:
10.1021/acs.analchem.8b01469. [PMID: 29842788] - Qinghua Hu, Changmin Yu, Xitao Xia, Fang Zeng, Shuizhu Wu. A fluorescent probe for simultaneous discrimination of GSH and Cys/Hcy in human serum samples via distinctly-separated emissions with independent excitations.
Biosensors & bioelectronics.
2016 Jul; 81(?):341-348. doi:
10.1016/j.bios.2016.03.011. [PMID: 26991600] - Lili Wang, Ying-Ying Zhang, Lei Wang, Feng-you Liu, Ling-Ling Cao, Jing Yang, Chunhua Qiao, Yonghao Ye. Benzofurazan derivatives as antifungal agents against phytopathogenic fungi.
European journal of medicinal chemistry.
2014 Jun; 80(?):535-42. doi:
10.1016/j.ejmech.2014.04.058. [PMID: 24813881] - Giorgio Cevasco, Anna Maria Piątek, Sergio Thea. HPLC determination of D-3-hydroxybutyric acid by derivatization with a benzofurazan reagent and fluorescent detection: application in the analysis of human plasma.
Clinica chimica acta; international journal of clinical chemistry.
2014 Feb; 429(?):90-5. doi:
10.1016/j.cca.2013.11.030. [PMID: 24315779] - Ulrich Kessler, Daniele Castagnolo, Mafalda Pagano, Davide Deodato, Martina Bernardini, Beatrice Pilger, Charlene Ranadheera, Maurizio Botta. Discovery and synthesis of novel benzofurazan derivatives as inhibitors of influenza A virus.
Bioorganic & medicinal chemistry letters.
2013 Oct; 23(20):5575-7. doi:
10.1016/j.bmcl.2013.08.048. [PMID: 24012120] - Leticia A Montoya, Taylor F Pearce, Ryan J Hansen, Lev N Zakharov, Michael D Pluth. Development of selective colorimetric probes for hydrogen sulfide based on nucleophilic aromatic substitution.
The Journal of organic chemistry.
2013 Jul; 78(13):6550-7. doi:
10.1021/jo4008095. [PMID: 23735055] - Christiaan J Malherbe, Dalene De Beer, Elizabeth Joubert. Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.
International journal of molecular sciences.
2012; 13(3):3101-3133. doi:
10.3390/ijms13033101. [PMID: 22489144] - Shogo Mitsuhashi, Takeshi Fukushima, Kotaro Arai, Masayuki Tomiya, Tomofumi Santa, Kazuhiro Imai, Toshimasa Toyo'oka. Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma.
Analytica chimica acta.
2007 Mar; 587(1):60-6. doi:
10.1016/j.aca.2007.01.033. [PMID: 17386754] - Osama Y Al-Dirbashi, Tomofumi Santa, Khalid Al-Qahtani, Mohammed Al-Amoudi, Mohamed S Rashed. Analysis of organic acid markers relevant to inherited metabolic diseases by ultra-performance liquid chromatography/tandem mass spectrometry as benzofurazan derivatives.
Rapid communications in mass spectrometry : RCM.
2007; 21(13):1984-90. doi:
10.1002/rcm.3053. [PMID: 17526065] - Yuhki Tsukamoto, Tomofumi Santa, Hiroshi Saimaru, Kazuhiro Imai, Takashi Funatsu. Synthesis of benzofurazan derivatization reagents for carboxylic acids and its application to analysis of fatty acids in rat plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.
Biomedical chromatography : BMC.
2005 Dec; 19(10):802-8. doi:
10.1002/bmc.523. [PMID: 15954158] - Carlos Velázquez, Edward E Knaus. Synthesis and biological evaluation of 1,4-dihydropyridine calcium channel modulators having a diazen-1-ium-1,2-diolate nitric oxide donor moiety for the potential treatment of congestive heart failure.
Bioorganic & medicinal chemistry.
2004 Jul; 12(14):3831-40. doi:
10.1016/j.bmc.2004.05.008. [PMID: 15210150] - Toshi Kajiro, Yuki Nakajima, Takeshi Fukushima, Kazuhiro Imai. A method to evaluate the renin-angiotensin system in rat renal cortex using a microdialysis technique combined with HPLC-fluorescence detection.
Analytical chemistry.
2002 Sep; 74(17):4519-25. doi:
10.1021/ac020059j. [PMID: 12236364]