Phenidone (BioDeep_00000744247)

   


代谢物信息卡片


Phenidone

化学式: C9H10N2O (162.079309)
中文名称: 菲尼酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN(NC1=O)C2=CC=CC=C2
InChI: InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)

描述信息

D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D004791 - Enzyme Inhibitors > D016859 - Lipoxygenase Inhibitors
D002491 - Central Nervous System Agents > D000700 - Analgesics
D020011 - Protective Agents > D000975 - Antioxidants
D000893 - Anti-Inflammatory Agents
Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[1][2]. Phenidone is used as a photographic developer[3].

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Phenidone



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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Xiaoman Li, Caiqiong Yang, Jianhua Chen, Yuanyuan He, Juncai Deng, Congwei Xie, Xinli Xiao, Xiyang Long, Xiaoling Wu, Weiguo Liu, Junbo Du, Feng Yang, Xiaochun Wang, Taiwen Yong, Jing Zhang, Yushan Wu, Wenyu Yang, Jiang Liu. Changing light promotes isoflavone biosynthesis in soybean pods and enhances their resistance to mildew infection. Plant, cell & environment. 2021 08; 44(8):2536-2550. doi: 10.1111/pce.14128. [PMID: 34118074]
  • Corinne Vanucci-Bacqué, Florence Bedos-Belval. Anti-inflammatory activity of naturally occuring diarylheptanoids - A review. Bioorganic & medicinal chemistry. 2021 02; 31(?):115971. doi: 10.1016/j.bmc.2020.115971. [PMID: 33422907]
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  • Lixin Wang, Peter Nick. Cold sensing in grapevine-Which signals are upstream of the microtubular 'thermometer'. Plant, cell & environment. 2017 Nov; 40(11):2844-2857. doi: 10.1111/pce.13066. [PMID: 28898434]
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  • Ivana Holková, Lýdia Bezáková, František Bilka, Andrea Balažová, Marián Vanko, Vítazoslava Blanáriková. Involvement of lipoxygenase in elicitor-stimulated sanguinarine accumulation in Papaver somniferum suspension cultures. Plant physiology and biochemistry : PPB. 2010 Oct; 48(10-11):887-92. doi: 10.1016/j.plaphy.2010.08.004. [PMID: 20829053]
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  • Maaike Bruinsma, Sarah van Broekhoven, Erik H Poelman, Maarten A Posthumus, Martin J Müller, Joop J A van Loon, Marcel Dicke. Inhibition of lipoxygenase affects induction of both direct and indirect plant defences against herbivorous insects. Oecologia. 2010 Feb; 162(2):393-404. doi: 10.1007/s00442-009-1459-x. [PMID: 19806367]
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  • Monika Frey, Dieter Spiteller, Wilhelm Boland, Alfons Gierl. Transcriptional activation of Igl, the gene for indole formation in Zea mays: a structure-activity study with elicitor-active N-acyl glutamines from insects. Phytochemistry. 2004 Apr; 65(8):1047-55. doi: 10.1016/j.phytochem.2003.11.021. [PMID: 15110684]
  • Bing Bing Lin, Tadayoshi Morita, Yun-Shan Lin, Hui-Ling Chen. A facile synthesis of 1-ethoxy-4-cyano-5-ethoxycarbonyl-3H-azuleno[1,2-c]pyran-3-one, a selective 15-lipoxygenase inhibitor. Bioorganic & medicinal chemistry letters. 2004 Jan; 14(1):63-5. doi: 10.1016/j.bmcl.2003.10.012. [PMID: 14684299]
  • Eun-Seon Kim, Eunyoung Choi, Youngsun Kim, Kyoungwon Cho, Ayoung Lee, Jaehan Shim, Randeep Rakwal, Ganesh Kumar Agrawal, Oksoo Han. Dual positional specificity and expression of non-traditional lipoxygenase induced by wounding and methyl jasmonate in maize seedlings. Plant molecular biology. 2003 Aug; 52(6):1203-13. doi: 10.1023/b:plan.0000004331.94803.b0. [PMID: 14682619]
  • Rattima Jeenapongsa, Krongtong Yoovathaworn, Kittima M Sriwatanakul, Ubonwan Pongprayoon, Kampon Sriwatanakul. Anti-inflammatory activity of (E)-1-(3,4-dimethoxyphenyl) butadiene from Zingiber cassumunar Roxb. Journal of ethnopharmacology. 2003 Aug; 87(2-3):143-8. doi: 10.1016/s0378-8741(03)00098-9. [PMID: 12860299]
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  • J C Bedick, H Tunaz, A R Nor Aliza, S M Putnam, M D Ellis, D W Stanley. Eicosanoids act in nodulation reactions to bacterial infections in newly emerged adult honey bees, Apis mellifera, but not in older foragers. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2001 Sep; 130(1):107-17. doi: 10.1016/s1532-0456(01)00226-5. [PMID: 11544147]
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