Dipyrone (BioDeep_00000744113)
代谢物信息卡片
Metamizole sodium
化学式: C13H16N3NaO4S (333.0759176)
中文名称: 安乃近
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)CS(=O)(=O)[O-].[Na+]
InChI: /q
描述信息
N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BB - Pyrazolones
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
D058633 - Antipyretics
同义名列表
2 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:59033
- KEGGdrug: D08190
- PubChem: 522325
- ChEMBL: CHEMBL487894
- MeSH: Dipyrone
- CAS: 68-89-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yu Cao, Bin Wu, Ying Xu, Mingchen Wang, Xinyu Wu, Xiaochen Liang, Jin Lin, Zhihai Li, Hua Lin, Cheng Luo, Shijie Chen. Discovery of GPX4 inhibitors through FP-based high-throughput screening.
European journal of medicinal chemistry.
2024 Feb; 265(?):116044. doi:
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Natural product research.
2023 May; 37(10):1709-1713. doi:
10.1080/14786419.2022.2104274. [PMID: 35879860] - Tobias Schneider, Eckhard Mauermann, Bernd Ilgenstein, Claude Jaquiery, Wilhelm Ruppen. Analgesic benefit of metamizole and ibuprofen vs. either medication alone: a randomized clinical trial.
Minerva anestesiologica.
2022 06; 88(6):448-456. doi:
10.23736/s0375-9393.22.16346-7. [PMID: 35416465] - Fabio Bachmann, Henriette E Meyer Zu Schwabedissen, Urs Duthaler, Stephan Krähenbühl. Cytochrome P450 1A2 is the most important enzyme for hepatic metabolism of the metamizole metabolite 4-methylaminoantipyrine.
British journal of clinical pharmacology.
2022 02; 88(4):1885-1896. doi:
10.1111/bcp.15108. [PMID: 34648192] - Daniela Fux, Moritz Metzner, Johanna Brandl, Melanie Feist, Magdalena Behrendt-Wippermann, Anne von Thaden, Christine Baumgartner. Pharmacokinetics of metamizole (dipyrone) as an add-on in calves undergoing umbilical surgery.
PloS one.
2022; 17(3):e0265305. doi:
10.1371/journal.pone.0265305. [PMID: 35290991] - İsmet Yılmaz, Zeynep Maraş, Yılmaz Uğur, Mustafa Erkan Özgür, Murat Durmaz, Halil İbrahim Ulusoy, Selim Erdoğan. Pharmacokinetic Profiles of Metamizole Metabolites after Intramuscular and Intravenous Administration in Healthy Arabian Horses.
Journal of veterinary pharmacology and therapeutics.
2021 Nov; 44(6):927-936. doi:
10.1111/jvp.13003. [PMID: 34431528] - Melinda Poole O'Banion, Emily Sundman, Matt Edmonds, Jennifer Davis. Pharmacokinetics of dipyrone in horses: A multi-dose, dose escalation study.
Journal of veterinary pharmacology and therapeutics.
2021 Nov; 44(6):919-926. doi:
10.1111/jvp.12996. [PMID: 34228836] - Laís Teixeira Bonfim, Tatiane Cristina Mota, Jéssica Juliana Gomes, Emerson da Silva, Lorena Monteiro Gomes, Rommel Mario Rodríguez Burbano, Marcelo Oliveira Bahia. Assessment of the cytoprotective effect of the homeopathic compound Canova® on African green monkey kidney (VERO) cell line exposed to the drug dipyrone sodium.
Journal of toxicology and environmental health. Part A.
2021 09; 84(18):761-768. doi:
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Journal of veterinary pharmacology and therapeutics.
2021 Sep; 44(5):842-849. doi:
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Annals of clinical biochemistry.
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Basic & clinical pharmacology & toxicology.
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2021 07; 394(7):1529-1535. doi:
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British journal of clinical pharmacology.
2021 07; 87(7):2902-2906. doi:
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Clinical pharmacology and therapeutics.
2021 06; 109(6):1505-1516. doi:
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2021 03; 87(3):1111-1119. doi:
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Veterinary anaesthesia and analgesia.
2020 Sep; 47(5):710-719. doi:
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Respiratory medicine.
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Journal of environmental management.
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Molecules (Basel, Switzerland).
2020 Feb; 25(3):. doi:
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The American journal of gastroenterology.
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2018 Oct; 41(5):699-705. doi:
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European journal of clinical pharmacology.
2018 May; 74(5):675-677. doi:
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Journal of veterinary pharmacology and therapeutics.
2018 Apr; 41(2):334-339. doi:
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European journal of anaesthesiology.
2018 04; 35(4):318-319. doi:
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European journal of anaesthesiology.
2018 04; 35(4):316-318. doi:
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Toxicology letters.
2018 Mar; 285(?):139-147. doi:
10.1016/j.toxlet.2017.12.021. [PMID: 29289696] - Masaki Yamamoto, Hideaki Nishimori, Takashi Fukutomi, Tokio Yamaguchi, Kazumasa Orihashi. Dynamics of Oxidative Stress Evoked by Myocardial Ischemia Reperfusion After Off-Pump Coronary Artery Bypass Grafting Elucidated by Bilirubin Oxidation.
Circulation journal : official journal of the Japanese Circulation Society.
2017 Oct; 81(11):1678-1685. doi:
10.1253/circj.cj-16-1116. [PMID: 28592749] - Thomas Stueber, Laura Buessecker, Andreas Leffler, Hans-Jörg Gillmann. The use of dipyrone in the ICU is associated with acute kidney injury: A retrospective cohort analysis.
European journal of anaesthesiology.
2017 10; 34(10):673-680. doi:
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Journal of natural products.
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The Journal of pharmacy and pharmacology.
2017 Jun; 69(6):642-651. doi:
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European journal of anaesthesiology.
2017 05; 34(5):288-296. doi:
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Journal of endourology.
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Medical archives (Sarajevo, Bosnia and Herzegovina).
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British journal of pharmacology.
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Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2014 Jan; 25(1):121-5. doi:
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Bioanalysis.
2013 Nov; 5(21):2631-45. doi:
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Klinische Padiatrie.
2013 Mar; 225(2):88-89. doi:
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Polskie Archiwum Medycyny Wewnetrznej.
2013; 123(5):257-8. doi:
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Journal of pharmaceutical and biomedical analysis.
2012 Dec; 71(?):173-8. doi:
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Journal of applied physiology (Bethesda, Md. : 1985).
2012 Nov; 113(9):1456-65. doi:
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Marine drugs.
2012 Sep; 10(9):1977-1992. doi:
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Naunyn-Schmiedeberg's archives of pharmacology.
2012 May; 385(5):527-38. doi:
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Inflammation.
2012 Apr; 35(2):420-8. doi:
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Scandinavian journal of urology and nephrology.
2012 Feb; 46(1):65-9. doi:
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Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2011 Aug; 41(8):1133-42. doi:
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Veterinary anaesthesia and analgesia.
2011 Jul; 38(4):385-93. doi:
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Reproductive biomedicine online.
2011 Jul; 23(1):132-40. doi:
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Praxis.
2011 Mar; 100(5):293-7. doi:
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Ecotoxicology and environmental safety.
2011 Mar; 74(3):342-9. doi:
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British journal of pharmacology.
2011 Mar; 162(6):1401-9. doi:
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Renal failure.
2011; 33(5):544-7. doi:
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European journal of pharmacology.
2010 Oct; 645(1-3):94-101. doi:
10.1016/j.ejphar.2010.07.019. [PMID: 20655302] - Rana Arslan, Nurcan Bektas. Antinociceptive effect of methanol extract of Capparis ovata in mice.
Pharmaceutical biology.
2010 Oct; 48(10):1185-90. doi:
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MMW Fortschritte der Medizin.
2010 Apr; 152(16):42-5; quiz 46. doi:
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Rinsho byori. The Japanese journal of clinical pathology.
2010 Apr; 58(4):313-8. doi:
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Archives of disease in childhood.
2010 Mar; 95(3):233-4. doi:
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Platelets.
2010; 21(8):610-5. doi:
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Medicinski arhiv.
2010; 64(2):113-5. doi:
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Phytotherapy research : PTR.
2010 Jan; 24(1):38-42. doi:
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European journal of pharmacology.
2009 Aug; 616(1-3):91-100. doi:
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American journal of physiology. Regulatory, integrative and comparative physiology.
2009 May; 296(5):R1631-40. doi:
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Bioanalysis.
2009 May; 1(2):293-8. doi:
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Pharmacology, biochemistry, and behavior.
2009 Jan; 91(3):321-6. doi:
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Forschende Komplementarmedizin (2006).
2008 Oct; 15(5):269-72. doi:
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Circulation journal : official journal of the Japanese Circulation Society.
2008 Sep; 72(9):1520-7. doi:
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Neurological research.
2008 Jun; 30(5):457-60. doi:
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Chemosphere.
2008 Apr; 71(9):1754-64. doi:
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Deutsche medizinische Wochenschrift (1946).
2008 Feb; 133(9):406-8. doi:
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Casopis lekaru ceskych.
2008; 147(7):392-5. doi:
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Journal of thrombosis and haemostasis : JTH.
2008 Jan; 6(1):166-73. doi:
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Terapevticheskii arkhiv.
2008; 80(6):62-5. doi:
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