Sodium citrate (BioDeep_00000744101)

   

PANOMIX_OTCML-2023


代谢物信息卡片


Sodium citrate

化学式: C6H5Na3O7 (257.972838)
中文名称: 柠檬酸钠
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Na+].[Na+].[Na+]
InChI: /q

描述信息

B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05C - Irrigating solutions > B05CB - Salt solutions
D000074385 - Food Ingredients > D005503 - Food Additives > D005520 - Food Preservatives
C78275 - Agent Affecting Blood or Body Fluid > C29730 - Electrolyte Replacement Agent
C78275 - Agent Affecting Blood or Body Fluid > C263 - Anticoagulant Agent
D006401 - Hematologic Agents > D000925 - Anticoagulants
D019995 - Laboratory Chemicals > D002021 - Buffers
Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice[1][2][3].

同义名列表

3 个代谢物同义名

Sodium citrate; Trisodium citrate anhydrous; Citric acid (trisodium)



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shiqi Lyu, Zurina Zainal Abidin, Thomas Choong Shean Yaw, Mohamad Faiz Mukhtar Gunam Resul. Inverse vulcanization induced oxygen modified porous polysulfides for efficient sorption of heavy metals. Environmental science and pollution research international. 2024 Mar; 31(11):16940-16957. doi: 10.1007/s11356-024-32323-z. [PMID: 38326685]
  • Miffy Hok Yan Cheng, Jerry Leung, Yao Zhang, Colton Strong, Genc Basha, Arash Momeni, Yihang Chen, Eric Jan, Amir Abdolahzadeh, Xinying Wang, Jayesh A Kulkarni, Dominik Witzigmann, Pieter R Cullis. Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency. Advanced materials (Deerfield Beach, Fla.). 2023 Aug; 35(31):e2303370. doi: 10.1002/adma.202303370. [PMID: 37172950]
  • Hui Yang, Yexuan Liu, Shengnan Wang, Lingling Zhao, He Liu, Jun Liu, Danshi Zhu. Composition, morphology, interfacial rheology and emulsifying ability of soy hull polysaccharides extracted with ammonium oxalate and sodium citrate as extractants. Journal of the science of food and agriculture. 2023 Mar; 103(5):2325-2336. doi: 10.1002/jsfa.12441. [PMID: 36628504]
  • Sofia M Borges, Cláudia Santos, M Fátima Macedo. Monocyte antigen-presenting capacity to iNKT cells is influenced by the blood collection conditions. Journal of immunological methods. 2023 02; 513(?):113426. doi: 10.1016/j.jim.2023.113426. [PMID: 36638882]
  • Anugrah Ray, Debjani Nath. Dose dependent intra-testicular accumulation of silver nanoparticles triggers morphometric changes in seminiferous tubules and Leydig cells and changes the structural integrity of spermatozoa chromatin. Theriogenology. 2022 Oct; 192(?):122-131. doi: 10.1016/j.theriogenology.2022.08.027. [PMID: 36088809]
  • Ping Lü, Hui-Li Li, Yong Xu, Xiao-Xu Zheng, Zhen-Hua Huang, Cong Wang, Sheng-Jun Xu, Xu-Liang Zhuang. [Effects of Nutrients on the Growth of Microcystis aeruginosa and Bacteria in the Phycosphere]. Huan jing ke xue= Huanjing kexue. 2022 Oct; 43(10):4502-4510. doi: 10.13227/j.hjkx.202201159. [PMID: 36224136]
  • Janis Fiedler, Zane Šmite, Silva Suvi, Saima Timpmann, Martin Mooses, Luule Medijainen, Eve Unt, Vahur Ööpik. Impact of sodium citrate ingestion during recovery after strenuous exercise in the heat on heart rate variability: A randomized, crossover study. Physiological reports. 2022 05; 10(9):e15280. doi: 10.14814/phy2.15280. [PMID: 35510322]
  • Jason C Siegler, Amelia J Carr, William T Jardine, Lilia Convit, Rebecca Cross, Dale Chapman, Louise M Burke, Megan Ross. The Hyperhydration Potential of Sodium Bicarbonate and Sodium Citrate. International journal of sport nutrition and exercise metabolism. 2022 03; 32(2):74-81. doi: 10.1123/ijsnem.2021-0179. [PMID: 34875625]
  • Ling-Sing Ch'ng, Charng Chee Toh, J R Sathiyananthan, Rohan Malek. Does alkalinised urine reduce the rate of encrustation in patients with ureteric stents? A randomised controlled study. International urology and nephrology. 2022 Mar; 54(3):509-515. doi: 10.1007/s11255-022-03105-8. [PMID: 35080681]
  • Peng Lu, Miaomiao Sui, Mimin Zhang, Mengyao Wang, Takehiro Kamiya, Ken Okamoto, Hideaki Itoh, Suguru Okuda, Michio Suzuki, Tomiko Asakura, Toru Fujiwara, Koji Nagata. Rosmarinic Acid and Sodium Citrate Have a Synergistic Bacteriostatic Effect against Vibrio Species by Inhibiting Iron Uptake. International journal of molecular sciences. 2021 Dec; 22(23):. doi: 10.3390/ijms222313010. [PMID: 34884815]
  • Shizhuang Weng, Xujin Hu, Wenxiu Zhu, Pan Li, Shouguo Zheng, Ling Zheng, Linsheng Huang, Dongyan Zhang. Surface-enhanced Raman spectroscopywith gold nanorods modified by sodium citrate and liquid-liquid interface self-extraction for detection of deoxynivalenol in Fusarium head blight-infected wheat kernels coupled with a fully convolution network. Food chemistry. 2021 Oct; 359(?):129847. doi: 10.1016/j.foodchem.2021.129847. [PMID: 33964656]
  • Armelle Vigouroux, Thibault Meyer, Anaïs Naretto, Pierre Legrand, Magali Aumont-Nicaise, Aurélie Di Cicco, Sébastien Renoud, Jeanne Doré, Daniel Lévy, Ludovic Vial, Céline Lavire, Solange Moréra. Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum. Nucleic acids research. 2021 01; 49(1):529-546. doi: 10.1093/nar/gkaa1181. [PMID: 33313837]
  • Shivani Chaturvedi, Amit K Gupta, Amrik Bhattacharya, Tanmay Dutta, Lata Nain, Sunil K Khare. Overexpression and repression of key rate-limiting enzymes (acetyl CoA carboxylase and HMG reductase) to enhance fatty acid production from Rhodotorula mucilaginosa. Journal of basic microbiology. 2021 Jan; 61(1):4-14. doi: 10.1002/jobm.202000407. [PMID: 32896907]
  • Charles S Urwin, Rodney J Snow, Liliana Orellana, Dominique Condo, Glenn D Wadley, Amelia J Carr. Does varying the ingestion period of sodium citrate influence blood alkalosis and gastrointestinal symptoms?. PloS one. 2021; 16(5):e0251808. doi: 10.1371/journal.pone.0251808. [PMID: 33999939]
  • Mahsa Zarei, Ehsan Karimi, Ehsan Oskoueian, Ali Es-Haghi, Mohammad Ehsan Taghavizadeh Yazdi. Comparative Study on the Biological Effects of Sodium Citrate-Based and Apigenin-Based Synthesized Silver Nanoparticles. Nutrition and cancer. 2021; 73(8):1511-1519. doi: 10.1080/01635581.2020.1801780. [PMID: 32757805]
  • Hidenori Ando, Kiyoshi Eshima, Tatsuhiro Ishida. Neutralization of Acidic Tumor Microenvironment (TME) with Daily Oral Dosing of Sodium Potassium Citrate (K/Na Citrate) Increases Therapeutic Effect of Anti-cancer Agent in Pancreatic Cancer Xenograft Mice Model. Biological & pharmaceutical bulletin. 2021; 44(2):266-270. doi: 10.1248/bpb.b20-00825. [PMID: 33518679]
  • Xuan Zhang, Jiawei Lin, Fang Pi, Tao Zhang, Chao Ai, Shujuan Yu. Rheological characterization of RG-I chicory root pectin extracted by hot alkali and chelators. International journal of biological macromolecules. 2020 Dec; 164(?):759-770. doi: 10.1016/j.ijbiomac.2020.07.020. [PMID: 32650011]
  • Xican Li, Jie Liu, Ban Chen, Yingci Chen, Wanjian Dai, Yuling Li, Meiling Zhu. Covalent Bridging of Corilagin Improves Antiferroptosis Activity: Comparison with 1,3,6-Tri-O-galloyl-β-d-glucopyranose. ACS medicinal chemistry letters. 2020 Nov; 11(11):2232-2237. doi: 10.1021/acsmedchemlett.0c00359. [PMID: 33214834]
  • Dan Xiao, Shuiqin Li, Baosong Gui, Jin Han, Zhaoyang Duan, Lining Jia, Yan Ou. Effect of uremic serum on Th17/Treg cell balance and endoplasmic reticulum stress in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 Nov; 131(?):110705. doi: 10.1016/j.biopha.2020.110705. [PMID: 32919190]
  • Valeriy D Zaytsev, Aleksei A Furletov, Vladimir V Apyari, Alexey V Garshev, Stanislava G Dmitrienko, Yury A Zolotov. Label-free silver triangular nanoplates for spectrophotometric determination of catecholamines and their metabolites. Mikrochimica acta. 2020 10; 187(11):610. doi: 10.1007/s00604-020-04576-1. [PMID: 33057848]
  • Eduardo Anitua, Mar Zalduendo, María Troya, Mohammad Hamdan Alkhraisat. The influence of sodium citrate on the characteristics and biological activity of plasma rich in growth factors. Regenerative medicine. 2020 10; 15(10):2181-2192. doi: 10.2217/rme-2020-0082. [PMID: 33275449]
  • Marion Mussbacher, Teresa L Krammer, Stefan Heber, Waltraud C Schrottmaier, Stephan Zeibig, Hans-Peter Holthoff, David Pereyra, Patrick Starlinger, Matthias Hackl, Alice Assinger. Impact of Anticoagulation and Sample Processing on the Quantification of Human Blood-Derived microRNA Signatures. Cells. 2020 08; 9(8):. doi: 10.3390/cells9081915. [PMID: 32824700]
  • Joanna Jung, Emily Garnett, Kesha Rector, Purviben Jariwala, Sridevi Devaraj. Effect of Collection Tube Type on Glucose Stability in Whole Blood. Annals of clinical and laboratory science. 2020 Jul; 50(4):557-559. doi: NULL. [PMID: 32826256]
  • Abir Aly Abbassy, Suad Trebinjac, Nehad Kotb. The use of cellular matrix in symptomatic knee osteoarthritis. Bosnian journal of basic medical sciences. 2020 May; 20(2):271-274. doi: 10.17305/bjbms.2019.4205. [PMID: 31538913]
  • Michiaki Abe, Tetsuya Akaishi, Mutsumi Shoji, Takuhiro Yamaguchi, Takashi Miki, Fumitoshi Satoh, Shin Takayama, Satomi Yamasaki, Kazuhiko Kawaguchi, Hiroshi Sato, Tadashi Ishii, Sadayoshi Ito. Reno-protective effects of oral alkalizing agents in chronic kidney disease with aciduria: protocol for a randomized cohort study. BMC nephrology. 2020 04; 21(1):144. doi: 10.1186/s12882-020-01807-8. [PMID: 32321450]
  • Chao Yang, Qingkang Liu, Xianghong Meng, Limin Cao, Bingjie Liu. Depuration of cadmium from Chlamys farreri by ZnSO4, EDTA-Na2 and sodium citrate in short time. Chemosphere. 2020 Apr; 244(?):125429. doi: 10.1016/j.chemosphere.2019.125429. [PMID: 31809923]
  • Yafei Wang, Yuqing Tang, Zhou Li, Qihang Hua, Li Wang, Xin Song, Baobo Zou, Min Ding, Jinshun Zhao, Chunlan Tang. Joint Toxicity of a Multi-Heavy Metal Mixture and Chemoprevention in Sprague Dawley Rats. International journal of environmental research and public health. 2020 02; 17(4):. doi: 10.3390/ijerph17041451. [PMID: 32102388]
  • Özge Lalegül-Ülker, Şükran Şeker, Ayşe Eser Elçin, Yaşar Murat Elçin. Encapsulation of bone marrow-MSCs in PRP-derived fibrin microbeads and preliminary evaluation in a volumetric muscle loss injury rat model: modular muscle tissue engineering. Artificial cells, nanomedicine, and biotechnology. 2019 Dec; 47(1):10-21. doi: 10.1080/21691401.2018.1540426. [PMID: 30514127]
  • M Abonnenc, D Crettaz, G Sonego, G Escolar, J-D Tissot, M Prudent. Towards the understanding of the UV light, riboflavin and additive solution contributions to the in vitro lesions observed in Mirasol®-treated platelets. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine. 2019 Nov; 26(4):209-216. doi: 10.1016/j.tracli.2019.09.001. [PMID: 31563447]
  • Stefany Laryssa Rosa, Bianca Martins Dos Santos, Felipe Augusto Soares, Saulo Hudson Nery Loiola, Sandra Valéria Inácio, Celso Tetsuo Nagase Suzuki, Edvaldo Sabadini, Alexandre Xavier Falcão, Kátia Denise Saraiva Bresciani, Jancarlo Ferreira Gomes. Use of the aqueous biphasic system as an alternative for concentration of Ascaris lumbricoides eggs, with non-toxic separation of faecal residues and fats. Tropical medicine & international health : TM & IH. 2019 11; 24(11):1320-1329. doi: 10.1111/tmi.13308. [PMID: 31505102]
  • Farah Asilah Azri, Jinap Selamat, Rashidah Sukor, Nor Azah Yusof, Nurul Hanun Ahmad Raston, Noordiana Nordin, Nuzul Noorahya Jambari. Etlingera elatior-Mediated Synthesis of Gold Nanoparticles and Their Application as Electrochemical Current Enhancer. Molecules (Basel, Switzerland). 2019 Aug; 24(17):. doi: 10.3390/molecules24173141. [PMID: 31470528]
  • Yunzhen Wu, Yuxia Zhang, Peng Wang, Zaiguo Wang, Guoliang Ren, Chunting Wang. [A mathematical calculation model of replacement fluid and citric acid infusion in continuous veno-venous hemofiltration]. Zhonghua wei zhong bing ji jiu yi xue. 2019 Jun; 31(6):725-730. doi: 10.3760/cma.j.issn.2095-4352.2019.06.013. [PMID: 31315731]
  • Ali Ghorbani, Saeed Yazdankhah, Mohamad Hasan Adel, Hamed Tabesh, Ali Reza Sattari, Shahab Aldin Sattari, Habib Heybar, Shahla Madjidi. Prevention of Contrast-induced Nephropathy in Patients with Chronic Kidney Disease Undergoing Elective Coronary Angioplasty or Angiography with Sodium Potassium Citrate Solution, a Double Blind Randomized Clinical Trial. Iranian journal of kidney diseases. 2019 05; 13(3):182-190. doi: NULL. [PMID: 31209191]
  • Bommenahalli Shashidhara Rashmi, Regupathi Iyyaswami. Aqueous two phase based selective extraction of mannose/glucose specific lectin from Indian cultivar of Pisum sativum seed. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 May; 1114-1115(?):13-23. doi: 10.1016/j.jchromb.2019.03.019. [PMID: 30913449]
  • Hanneke Buter, Matty Koopmans, Peter H J van der Voort. Strong ion difference and CVVH: Different response during nadroparin versus citrate anticoagulation. Journal of critical care. 2018 10; 47(?):88-92. doi: 10.1016/j.jcrc.2018.06.006. [PMID: 29936328]
  • Yui Takashina, Aya Manabe, Hajime Hasegawa, Toshiyuki Matsunaga, Satoshi Endo, Akira Ikari. Sodium Citrate Increases Expression and Flux of Mg2+ Transport Carriers Mediated by Activation of MEK/ERK/c-Fos Pathway in Renal Tubular Epithelial Cells. Nutrients. 2018 Sep; 10(10):. doi: 10.3390/nu10101345. [PMID: 30241394]
  • Takahiro Yamauchi, Shigehiro Doi, Ayumu Nakashima, Toshiki Doi, Eisei Sohara, Shinichi Uchida, Takao Masaki. Na+-Cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats. American journal of physiology. Renal physiology. 2018 08; 315(2):F300-F312. doi: 10.1152/ajprenal.00504.2016. [PMID: 29631358]
  • Daniel Christiadi, Chari Mercado, Richard Singer. Regional citrate anticoagulation in membrane based plasma exchange: Safety, efficacy and effect on calcium balance. Nephrology (Carlton, Vic.). 2018 Aug; 23(8):744-747. doi: 10.1111/nep.13088. [PMID: 28618127]
  • Franz Ratzinger, Mona Lang, Sabine Belik, Klaus G Schmetterer, Helmuth Haslacher, Thomas Perkmann, Peter Quehenberger. The Effect of 3.2\% and 3.8\% Sodium Citrate on Specialized Coagulation Tests. Archives of pathology & laboratory medicine. 2018 08; 142(8):992-997. doi: 10.5858/arpa.2017-0200-oa. [PMID: 29624078]
  • Francesco Trepiccione, Claudia Altobelli, Giovambattista Capasso, Birgitte Mønster Christensen, Sebastian Frische. Lithium increases ammonium excretion leading to altered urinary acid-base buffer composition. Journal of nephrology. 2018 06; 31(3):385-393. doi: 10.1007/s40620-017-0460-4. [PMID: 29178032]
  • Silva Suvi, Martin Mooses, Saima Timpmann, Luule Medijainen, Daria Narõškina, Eve Unt, Vahur Ööpik. Impact of sodium citrate ingestion during recovery after dehydrating exercise on rehydration and subsequent 40-km cycling time-trial performance in the heat. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2018 Jun; 43(6):571-579. doi: 10.1139/apnm-2017-0584. [PMID: 29324186]
  • Jeffrey A Kraut, Nicolaos E Madias. Retarding progression of chronic kidney disease: use of modalities that counter acid retention. Current opinion in nephrology and hypertension. 2018 03; 27(2):94-101. doi: 10.1097/mnh.0000000000000386. [PMID: 29140821]
  • Ksenia Germanovich, Eti Alessandra Femia, Chun Yan Cheng, Natalia Dovlatova, Marco Cattaneo. Effects of pH and concentration of sodium citrate anticoagulant on platelet aggregation measured by light transmission aggregometry induced by adenosine diphosphate. Platelets. 2018 Jan; 29(1):21-26. doi: 10.1080/09537104.2017.1327655. [PMID: 28643541]
  • Adriana R Marques, Xiuli Yang, Alexis A Smith, Xuran Zhuang, Siu-Ping Turk, Carla D Williams, Melissa A Law, Alan G Barbour, Utpal Pal. Citrate Anticoagulant Improves the Sensitivity of Borreliella (Borrelia) burgdorferi Plasma Culture. Journal of clinical microbiology. 2017 11; 55(11):3297-3299. doi: 10.1128/jcm.01046-17. [PMID: 28878005]
  • Walter J Janse van Rensburg, Patricia van der Merwe. Comparison of Commercially Available Blood Collection Tubes Containing Sodium Citrate and Hirudin in Platelet Aggregation Testing. Medical science monitor basic research. 2017 Jul; 23(?):264-269. doi: 10.12659/msmbr.905246. [PMID: 28747619]
  • Luis E F Almeida, Sayuri Kamimura, Margaret Y Nettleton, Celia M de Souza Batista, Elizabeth Walek, Alfia Khaibullina, Li Wang, Zenaide M N Quezado. Blood collection vials and clinically used intravenous fluids contain significant amounts of nitrite. Free radical biology & medicine. 2017 07; 108(?):533-541. doi: 10.1016/j.freeradbiomed.2017.04.014. [PMID: 28416347]
  • Mahsa Alizadeh, Ryan L Wood, Clara M Buchanan, Colin G Bledsoe, Madison E Wood, Daniel S McClellan, Rae Blanco, Tanner V Ravsten, Ghaleb A Husseini, Caroline L Hickey, Richard A Robison, William G Pitt. Rapid separation of bacteria from blood - Chemical aspects. Colloids and surfaces. B, Biointerfaces. 2017 Jun; 154(?):365-372. doi: 10.1016/j.colsurfb.2017.03.027. [PMID: 28365426]
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