Ancitabine hydrochloride (BioDeep_00000743741)

   


代谢物信息卡片


Cyclocytidine Hydrochloride

化学式: C9H12ClN3O4 (261.0516302)
中文名称: 盐酸环胞苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl
InChI: /m1./s1

描述信息

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite
D009676 - Noxae > D000963 - Antimetabolites
D000970 - Antineoplastic Agents
Ancitabine (hydrochloride) is an important antileukemia drugs.

同义名列表

5 个代谢物同义名

Cyclocytidine Hydrochloride; Ancitabine hydrochloride; Cyclo-CMP hydrochloride; Cyclo-C; Ancitabine (hydrochloride)



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yuxue Yang, Yuxin Gao, Yang Liu, Bilin Liu, Di Wang, Yunping Xu, Yuli Wei. Pseudomonas marianensis sp. nov., a marine bacterium isolated from deep-sea sediments of the Mariana Trench. Archives of microbiology. 2022 Sep; 204(10):638. doi: 10.1007/s00203-022-03250-9. [PMID: 36131209]
  • Santosh K Maurya, Akhilesh Kumar Maurya, Nidhi Mishra, Hifzur R Siddique. Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2. Journal of receptor and signal transduction research. 2020 Dec; 40(6):605-612. doi: 10.1080/10799893.2020.1772298. [PMID: 32476594]
  • G N Thomopoulos, J R Garrett, G B Proctor. Ultrastructural histochemical studies of secretory processes in rat submandibular granular tubules during intermittent sympathetic nerve stimulation. European journal of morphology. 2000 Apr; 38(2):69-79. doi: 10.1076/0924-3860(200004)38:2;1-f;ft069. [PMID: 10694903]
  • G N Thomopoulos, J R Garrett, G B Proctor, R Hartley, X S Zhang. Exocytosis from rat submandibular granular tubules during cyclocytidine stimulation shows unusual features, including changes in the granule membrane. Microscopy research and technique. 1996 Dec; 35(5):365-76. doi: 10.1002/(sici)1097-0029(19961201)35:5<365::aid-jemt1>3.0.co;2-k. [PMID: 8989766]
  • K Nakamura, Y Eizuru, K Kumura, Y Minamishima. Antiviral effect of antileukemic drugs N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) and 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine (cyclo-C) against human cytomegalovirus. Journal of medical virology. 1990 Jun; 31(2):141-7. doi: 10.1002/jmv.1890310212. [PMID: 1696958]
  • L Novotný, H Farghali, I Janků, J Beránek. Comparative study of cyclocytidine and arabinosylcytosine disposition in rats. Neoplasma. 1988; 35(6):707-14. doi: NULL. [PMID: 2464769]
  • L E Kirsch, R E Notari. Pharmacokinetic prodrug modeling: in vitro and in vivo kinetics and mechanisms of ancitabine bioconversion to cytarabine. Journal of pharmaceutical sciences. 1984 Jun; 73(6):728-32. doi: 10.1002/jps.2600730606. [PMID: 6204036]
  • T Nakamura, T Ueda. [Chemotherapy of the malignancies from the viewpoint of pharmacology and biochemistry of cytosine arabinoside (ara-C) and its derivatives]. Gan to kagaku ryoho. Cancer & chemotherapy. 1982 Aug; 9(8):1339-51. doi: NULL. [PMID: 6191711]
  • K J Himmelstein, J F Gross. Mathematical model for cyclocytidine pharmacokinetics. Journal of pharmaceutical sciences. 1977 Oct; 66(10):1441-4. doi: 10.1002/jps.2600661024. [PMID: 72816]
  • T C Chou, P Vidal, F S Phillips. Comparison of tissue distribution and fate of 2,2'-anhydro-1-beta-D-arabinofuranosyl-5-fluorocytosine and 1-beta-D-arabinofuranosyl-5-fluorocytosine in rats. Cancer treatment reports. 1977 Jul; 61(4):617-24. doi: NULL. [PMID: 69496]
  • T Nakamura, M Sasada, H Sawada, T Higuchi, K Tatsumi. [Chemotherapy of acute leukemia with cyclocytidine, with special reference to serum ara-C deaminase activity (author's transl)]. Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society. 1977 Jun; 40(3):293-9. doi: NULL. [PMID: 72473]
  • K Sato, A Nomura, J G Moffatt. Antiviral activities of acyl derivatives of 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosylcytosine in cell culture. Antimicrobial agents and chemotherapy. 1977 Feb; 11(2):191-7. doi: 10.1128/aac.11.2.191. [PMID: 66909]