Etimicin (BioDeep_00000740791)
代谢物信息卡片
化学式: C21H43N5O7 (477.3162)
中文名称: 依替米星
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCNC1CC(C(C(C1OC2C(C(C(CO2)(C)O)NC)O)O)OC3C(CCC(O3)CN)N)N
InChI: InChI=1S/C21H43N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)14(27)17(13)33-20-15(28)18(25-3)21(2,29)9-30-20/h10-20,25-29H,4-9,22-24H2,1-3H3/t10-,11+,12-,13+,14-,15+,16+,17-,18+,19+,20+,21-/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Weihao Shao, Dan Zhong, Haowei Jiang, Yujie Han, Yu Yin, Ruining Li, Xiuping Qian, Daijie Chen, Lili Jing. A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos.
Journal of applied toxicology : JAT.
2021 07; 41(7):1063-1075. doi:
10.1002/jat.4093. [PMID: 33094525] - Lan Yao, Jing-Wei Zhang, Bin Chen, Ming-Min Cai, Dong Feng, Qi-Zhi Wang, Xin-Yu Wang, Jian-Guo Sun, Yi-Wen Zheng, Guang-Ji Wang, Fang Zhou. Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin.
Acta pharmacologica Sinica.
2020 Jun; 41(6):866-878. doi:
10.1038/s41401-019-0342-5. [PMID: 31937930] - Guo-Ying Zuo, Cui-Xian Yang, Jun Han, Yu-Qing Li, Gen-Chun Wang. Synergism of prenylflavonoids from Morus alba root bark against clinical MRSA isolates.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2018 Jan; 39(?):93-99. doi:
10.1016/j.phymed.2017.12.023. [PMID: 29433688] - Lan Yao, Fang Zhou, Mingmin Cai, Ying Peng, Jianguo Sun, Qianying Chen, Xiaoliang Jin, Guangji Wang, Jingwei Zhang. Development and validation of a sensitive LC-MS/MS method without derivatization/ion-pairing agents for etimicin quantification in rat plasma, internal ear and kidney.
Journal of pharmaceutical and biomedical analysis.
2017 Nov; 146(?):96-102. doi:
10.1016/j.jpba.2017.08.027. [PMID: 28881316] - Z-D Li, X-L Zhang, N Yi, F-C Zhang. Elimination of etimicin in rat kidneys and alterations of its cytotoxicity to tubular epithelial cells.
Human & experimental toxicology.
2015 May; 34(5):479-86. doi:
10.1177/0960327114550887. [PMID: 25233899] - Yafeng Zhuang, Lu Cao. Sensitive fluorescence detection of etimicin based on derivatives of formaldehyde and acetylacetone.
Journal of fluorescence.
2013 Jan; 23(1):1-5. doi:
10.1007/s10895-012-1121-6. [PMID: 22918626] - Lei Wang, Juanjuan Peng, Zhengwen Liu, Youqiu He. Resonance Rayleigh-scattering spectral method for the determination of some aminoglycoside antibiotics using CdTe quantum dots as a probe.
Luminescence : the journal of biological and chemical luminescence.
2010 Nov; 25(6):424-30. doi:
10.1002/bio.1170. [PMID: 19743528] - Hai-Xue Wang, Li-Rong Zhang, Xiao-Chao Ma, Tong-Xun Ma. Influence of piperacillin on pharmacokinetics of etimicin in healthy volunteers.
Acta pharmacologica Sinica.
2002 Apr; 23(4):376-80. doi:
NULL. [PMID: 11931698]
