Tolvin (BioDeep_00000000740)

PANOMIX_OTCML-2023

代谢物信息卡片

5-methyl-2,5-diazatetracyclo[13.4.0.0^{2,7.0^{8,13]nonadeca-1(19),8,10,12,15,17-hexaene;hydrochloride

化学式: C18H21ClN2 (300.1393176)
中文名称: 米安舍林盐酸盐, 盐酸米安色林, 盐酸米安色林
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 55.47%

分子结构信息

SMILES: CN(CC1)CC2N1C3=CC=CC=C3CC4=CC=CC=C24.Cl
InChI: 1H

描述信息

A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists
C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist
C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent
Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.
Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

同义名列表

54 个代谢物同义名

5-methyl-2,5-diazatetracyclo[13.4.0.0^{2,7.0^{8,13]nonadeca-1(19),8,10,12,15,17-hexaene;hydrochloride; Hydron;5-methyl-2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaene;chloride; 5-methyl-2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaene;hydrochloride; Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, hydrochloride (1:1); Dibenzo(c,f)pyrazino(1,2-a)azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, monohydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]-pyrazino[1,2-a]azepine monohydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)-pyrazino(1,2-a)azepine monohydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldi benzo[c,f]pyrazino[1,2-a]azepine hydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine hydrochloride; 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyryzino[1,2-a]azepine hydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride; Mianserin for system suitability, European Pharmacopoeia (EP) Reference Standard; 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepinehydrochloride; Mianserin hydrochloride, European Pharmacopoeia (EP) Reference Standard; Mianserin hydrochloride, analytical standard, for drug analysis; Mianserin Hydrochloride 1.0 mg/ml in Methanol (as free base); MIANSERIN HYDROCHLORIDE [EP MONOGRAPH]; Mianserin hydrochloride (JAN/USAN); Mianserin hydrochloride [USAN:JAN]; Mianserin.HCl, 1mg/ml in Methanol; Mianserin for system suitability; MIANSERIN HYDROCHLORIDE [WHO-DD]; MIANSERIN HYDROCHLORIDE [MART.]; MIANSERIN HYDROCHLORIDE [USAN]; MIANSERIN HYDROCHLORIDE [JAN]; Monohydrochloride, Mianserin; MIANSERIN HYDROCHLORIDE [MI]; Mianserin Monohydrochloride; Mianserin (hydrochloride); Hydrochloride, Mianserin; Mianserine hydrochloride; Mianserin hydrochloride; UNII-2X03TN217S; mianserine HCl; Tetramide (TN); (.+-.)-Athymil; Mianserin.HCl; ORG GB-94 HCl; (.+-.)-Norval; Mianserin HCl; Tox21_500744; C18H20N2.HCl; 2X03TN217S; ORG-GB 94; Org GB 94; Tetramide; Mianserin; Bolvidon; Athymil; Lerivon; Tolvin; Tolvon; GB 94

数据库引用编号

10 个数据库交叉引用编号

ChEBI: CHEBI:31843
KEGG: C74052
KEGGdrug: D01358
PubChem: 68551
ChEMBL: CHEMBL544428
MeSH: Mianserin
ChemIDplus: 0021535477
CAS: 21535-47-7
CAS: 78644-54-9
medchemexpress: HY-B0188A

分类词条

生物碱

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Dandan Liu, Xinxin Zhang, Fang Chiqin, Innocent Nyamwasa, Yazhong Cao, Jiao Yin, Shuai Zhang, Honglin Feng, Kebin Li. Octopamine modulates insect mating and Oviposition. Journal of chemical ecology. 2022 Aug; 48(7-8):628-640. doi: 10.1007/s10886-022-01366-2. [PMID: 35687218]
Suguru Kato, Abhi Shah, Mihaela Plesescu, Yoshinari Miyata, Jayaprakasam Bolleddula, Swapan Chowdhury, Xiaochun Zhu. Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver. Drug metabolism and disposition: the biological fate of chemicals. 2020 10; 48(10):934-943. doi: 10.1124/dmd.120.000128. [PMID: 32665417]
Masataka Shinozaki, Jason Pierce, Yuki Hayashi, Takashi Watanabe, Taro Sasaki, Hazuki Komahashi-Sasaki, Kazufumi Akiyama, Kazuko Kato, Yoshimasa Inoue, Shoko Tsuchimine, Norio Yasui-Furukori, Yuji Ozeki, Kazutaka Shimoda. 8-Hydroxylation and Glucuronidation of Mirtazapine in Japanese Psychiatric Patients: Significance of the Glucuronidation Pathway of 8-Hydroxy-Mirtazapine. Pharmacopsychiatry. 2019 Sep; 52(5):237-244. doi: 10.1055/a-0918-6408. [PMID: 31158907]
Danyi Lu, Dong Dong, Qian Xie, Zhijie Li, Baojian Wu. Disposition of Mianserin and Cyclizine in UGT2B10-Overexpressing Human Embryonic Kidney 293 Cells: Identification of UGT2B10 as a Novel N-Glucosidation Enzyme and Breast Cancer Resistance Protein as an N-Glucoside Transporter. Drug metabolism and disposition: the biological fate of chemicals. 2018 07; 46(7):970-979. doi: 10.1124/dmd.118.080804. [PMID: 29691239]
Julia Ríos-Gómez, Beatriz Fresco-Cala, María Teresa García-Valverde, Rafael Lucena, Soledad Cárdenas. Carbon Nanohorn Suprastructures on a Paper Support as a Sorptive Phase. Molecules (Basel, Switzerland). 2018 May; 23(6):. doi: 10.3390/molecules23061252. [PMID: 29794967]
Michael Paulzen, Ekkehard Haen, Christoph Hiemke, Bianca Fay, Sandra Unholzer, Gerhard Gründer, Georgios Schoretsanitis. Antidepressant polypharmacy and the potential of pharmacokinetic interactions: Doxepin but not mirtazapine causes clinically relevant changes in venlafaxine metabolism. Journal of affective disorders. 2018 02; 227(?):506-511. doi: 10.1016/j.jad.2017.11.046. [PMID: 29156365]
Manish K Jha, Abu Minhajuddin, Bharathi S Gadad, Tracy L Greer, Taryn L Mayes, Madhukar H Trivedi. Interleukin 17 selectively predicts better outcomes with bupropion-SSRI combination: Novel T cell biomarker for antidepressant medication selection. Brain, behavior, and immunity. 2017 Nov; 66(?):103-110. doi: 10.1016/j.bbi.2017.07.005. [PMID: 28698115]
Alaa E El-Sisi, Magda E El-Sayad, Nermine M Abdelsalam. Protective effects of mirtazapine and chrysin on experimentally induced testicular damage in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 Nov; 95(?):1059-1066. doi: 10.1016/j.biopha.2017.09.022. [PMID: 28922723]
Kellyi K Benson, Lara B Zajic, Paula K Morgan, Sarah R Brown, Ryan J Hansen, Paul J Lunghofer, Luke A Wittenburg, Daniel L Gustafson, Jessica M Quimby. Drug exposure and clinical effect of transdermal mirtazapine in healthy young cats: a pilot study. Journal of feline medicine and surgery. 2017 Oct; 19(10):998-1006. doi: 10.1177/1098612x16667168. [PMID: 27613493]
Tatiana de Queiroz Oliveira, Caren Nádia Soares de Sousa, Germana Silva Vasconcelos, Luciene Costa de Sousa, Anneheydi Araújo de Oliveira, Cláudio Felipe Vasconcelos Patrocínio, Ingridy da Silva Medeiros, José Eduardo Ribeiro Honório Júnior, Michael Maes, Danielle Macedo, Silvânia Maria Mendes Vasconcelos. Brain antioxidant effect of mirtazapine and reversal of sedation by its combination with alpha-lipoic acid in a model of depression induced by corticosterone. Journal of affective disorders. 2017 09; 219(?):49-57. doi: 10.1016/j.jad.2017.05.022. [PMID: 28521187]
Dalia M El-Tanbouly, Walaa Wadie, Rabab H Sayed. Modulation of TGF-β/Smad and ERK signaling pathways mediates the anti-fibrotic effect of mirtazapine in mice. Toxicology and applied pharmacology. 2017 08; 329(?):224-230. doi: 10.1016/j.taap.2017.06.012. [PMID: 28623179]
Johanna Weber, Stefanie Oberfeld, Andrea Bonse, Klaus Telger, Rainer Lingg, Georg Hempel. Validation of a dried blood spot method for therapeutic drug monitoring of citalopram, mirtazapine and risperidone and its active metabolite 9-hydroxyrisperidone using HPLC-MS. Journal of pharmaceutical and biomedical analysis. 2017 Jun; 140(?):347-354. doi: 10.1016/j.jpba.2017.02.061. [PMID: 28395245]
Vassiliki A Boumba, Georgios N Rallis, Theodore Vougiouklakis. Poisoning suicide with ingestion of the pyrethroids alpha-cypermethrin and deltamethrin and the antidepressant mirtazapine: A case report. Forensic science international. 2017 May; 274(?):75-78. doi: 10.1016/j.forsciint.2016.11.023. [PMID: 27899216]
Mahdi Ghorbani, Mahmoud Chamsaz, Gholam Hossein Rounaghi, Mohsen Aghamohammadhasani, Orkideh Seyedin, Nahid Afshar Lahoori. Development of a novel ultrasonic-assisted magnetic dispersive solid-phase microextraction method coupled with high performance liquid chromatography for determination of mirtazapine and its metabolites in human urine and water samples employing experimental design. Analytical and bioanalytical chemistry. 2016 Nov; 408(27):7719-7729. doi: 10.1007/s00216-016-9869-1. [PMID: 27562753]
Eiichi Ohnuki, Shinya Asayama, Tomoko Asayama, Kazuo Nakamichi, Masayuki Saijo, Satoru Kosaka. A case of progressive multifocal leukoencephalopathy with chronic renal failure, whose JC virus in cerebrospinal fluid disappeared after mefloquine-mirtazapine dual therapy. Rinsho shinkeigaku = Clinical neurology. 2016 10; 56(10):705-708. doi: 10.5692/clinicalneurol.cn-000928. [PMID: 27645758]
W Zheng, Y F Zhang, H Q Zhong, S M Mai, X H Yang, Y T Xiang. Wuling Capsule for Major Depressive Disorder: A Meta-analysis of Randomised Controlled Trials. East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan. 2016 Sep; 26(3):87-97. doi: ". [PMID: 27703096]
M Julia García-Fuster, Jesús A García-Sevilla. Effects of anti-depressant treatments on FADD and p-FADD protein in rat brain cortex: enhanced anti-apoptotic p-FADD/FADD ratio after chronic desipramine and fluoxetine administration. Psychopharmacology. 2016 Aug; 233(15-16):2955-71. doi: 10.1007/s00213-016-4342-6. [PMID: 27259485]
Shu-Man Jiang, Lin Jia, Jing Liu, Man-Man Shi, Ming-Zhi Xu. Beneficial effects of antidepressant mirtazapine in functional dyspepsia patients with weight loss. World journal of gastroenterology. 2016 Jun; 22(22):5260-6. doi: 10.3748/wjg.v22.i22.5260. [PMID: 27298569]
S Rzezniczek, M Obuchowicz, W Datka, M Siwek, D Dudek, K Kmiotek, K Oved, N Shomron, D Gurwitz, A Pilc. Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients. Translational psychiatry. 2016 05; 6(5):e827. doi: 10.1038/tp.2016.90. [PMID: 27244236]
Katja Biering Leth-Møller, Annette Højmann Hansen, Maia Torstensson, Stig Ejdrup Andersen, Lars Ødum, Gunnar Gislasson, Christian Torp-Pedersen, Ellen Astrid Holm. Antidepressants and the risk of hyponatremia: a Danish register-based population study. BMJ open. 2016 05; 6(5):e011200. doi: 10.1136/bmjopen-2016-011200. [PMID: 27194321]
Ewa Poleszak, Aleksandra Szopa, Elżbieta Wyska, Wirginia Kukuła-Koch, Anna Serefko, Sylwia Wośko, Karolina Bogatko, Andrzej Wróbel, Piotr Wlaź. Caffeine augments the antidepressant-like activity of mianserin and agomelatine in forced swim and tail suspension tests in mice. Pharmacological reports : PR. 2016 Feb; 68(1):56-61. doi: 10.1016/j.pharep.2015.06.138. [PMID: 26721352]
Mirte Smit, Koert M Dolman, A Honig. Mirtazapine in pregnancy and lactation - A systematic review. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2016 Jan; 26(1):126-135. doi: 10.1016/j.euroneuro.2015.06.014. [PMID: 26631373]
Rachna Gupta, Keshav Gupta, A K Tripathi, M S Bhatia, Lalit K Gupta. Effect of Mirtazapine Treatment on Serum Levels of Brain-Derived Neurotrophic Factor and Tumor Necrosis Factor-α in Patients of Major Depressive Disorder with Severe Depression. Pharmacology. 2016; 97(3-4):184-8. doi: 10.1159/000444220. [PMID: 26854819]
Chi-Shun Wu, Show-Hwa Tong, Cheung-Ter Ong, Sheng-Feng Sung. Serotonin Syndrome Induced by Combined Use of Mirtazapine and Olanzapine Complicated with Rhabdomyolysis, Acute Renal Failure, and Acute Pulmonary Edema-A Case Report. Acta neurologica Taiwanica. 2015 Dec; 24(4):117-21. doi: . [PMID: 27333965]
M Deuschle, M Gilles, B Scharnholz, K G Kahl. Antidepressant Treatment with Venlafaxine and Mirtazapine: no Effect on Serum Concentration of Vascular Endothelial Growth Factor (VEGF). Pharmacopsychiatry. 2015 Nov; 48(7):292-3. doi: 10.1055/s-0035-1555849. [PMID: 26190286]
Y Hayashi, T Watanabe, A Aoki, S Ishiguro, M Ueda, K Akiyama, K Kato, Y Inoue, S Tsuchimine, N Yasui-Furukori, K Shimoda. Factors Affecting Steady-state Plasma Concentrations of Enantiomeric Mirtazapine and its Desmethylated Metabolites in Japanese Psychiatric Patients. Pharmacopsychiatry. 2015 Nov; 48(7):279-85. doi: 10.1055/s-0035-1565069. [PMID: 26595747]
Hisatake Matsumoto, Mitsuo Ohnishi, Ryosuke Takegawa, Tomoya Hirose, Yuji Hattori, Takeshi Shimazu. Effect of lipid emulsion during resuscitation of a patient with cardiac arrest after overdose of chlorpromazine and mirtazapine. The American journal of emergency medicine. 2015 Oct; 33(10):1541.e1-2. doi: 10.1016/j.ajem.2015.07.059. [PMID: 26314213]
Frank M Schmidt, Claudia Nowak, Juergen Kratzsch, Christian Sander, Ulrich Hegerl, Peter Schönknecht. Dynamics of melanin-concentrating hormone (MCH) serum levels in major depressive disorder during antidepressant treatment. Journal of affective disorders. 2015 Jul; 180(?):207-13. doi: 10.1016/j.jad.2015.03.039. [PMID: 25932975]
Yuta Yoshino, Shinichiro Ochi, Kiyohiro Yamazaki, Shunsuke Nakata, Masao Abe, Yoko Mori, Shu-ichi Ueno. Antidepressant action via the nitric oxide system: A pilot study in an acute depressive model induced by arginin. Neuroscience letters. 2015 Jul; 599(?):69-74. doi: 10.1016/j.neulet.2015.05.043. [PMID: 26007704]
Maria C Olianas, Simona Dedoni, Pierluigi Onali. Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts. Biochemical pharmacology. 2015 Jun; 95(4):311-23. doi: 10.1016/j.bcp.2015.04.002. [PMID: 25888927]
Michael Paulzen, Gerhard Gründer, Simone C Tauber, Tanja Veselinovic, Christoph Hiemke, Sarah E Groppe. Distribution pattern of mirtazapine and normirtazapine in blood and CSF. Psychopharmacology. 2015 Feb; 232(4):807-13. doi: 10.1007/s00213-014-3717-9. [PMID: 25150039]
Maho Okubo, Norie Murayama, Jun Miura, Yasuji Chiba, Hiroshi Yamazaki. Effects of cytochrome P450 2D6 and 3A5 genotypes and possible coadministered medicines on the metabolic clearance of antidepressant mirtazapine in Japanese patients. Biochemical pharmacology. 2015 Jan; 93(1):104-9. doi: 10.1016/j.bcp.2014.11.011. [PMID: 25475885]
Saliha Ozsoy, Aslı Besirli, Dilek Unal, Ummuhan Abdulrezzak, Okan Orhan. The association between depression, weight loss and leptin/ghrelin levels in male patients with head and neck cancer undergoing radiotherapy. General hospital psychiatry. 2015 Jan; 37(1):31-5. doi: 10.1016/j.genhosppsych.2014.09.002. [PMID: 25440723]
Maria Giese, Johannes Beck, Serge Brand, Flavio Muheim, Ulrich Hemmeter, Martin Hatzinger, Edith Holsboer-Trachsler, Anne Eckert. Fast BDNF serum level increase and diurnal BDNF oscillations are associated with therapeutic response after partial sleep deprivation. Journal of psychiatric research. 2014 Dec; 59(?):1-7. doi: 10.1016/j.jpsychires.2014.09.005. [PMID: 25258340]
Hoo Rim Song, Young Sup Woo, Hee-Ryung Wang, In-Hee Shim, Tae-Youn Jun, Won-Myong Bahk. Does mirtazapine interfere with naturalistic diabetes treatment?. Journal of clinical psychopharmacology. 2014 Oct; 34(5):588-94. doi: 10.1097/jcp.0000000000000183. [PMID: 24987796]
Keith A Hermanstyne, Glenn-Milo Santos, Eric Vittinghoff, Deirdre Santos, Grant Colfax, Phillip Coffin. Event-level relationship between methamphetamine use significantly associated with non-adherence to pharmacologic trial medications in event-level analyses. Drug and alcohol dependence. 2014 Oct; 143(?):277-80. doi: 10.1016/j.drugalcdep.2014.07.031. [PMID: 25156227]
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Hun Soo Chang, Hwa-Young Lee, Ji-Hyun Cha, Eun Soo Won, Byung-Joo Ham, Bohye Kim, Min-Soo Lee. Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirtazapine in patients with major depressive disorder. Journal of clinical psychopharmacology. 2014 Aug; 34(4):446-54. doi: 10.1097/jcp.0000000000000143. [PMID: 24911443]
N N Darmograĭ, I I Gal'kevich. [The identification and quantitative measurement of mirtazapine isolated from the biological material by high performance liquid chromatography]. Sudebno-meditsinskaia ekspertiza. 2014 Jan; 57(1):37-40. doi: NULL. [PMID: 25275184]
Fionn E O'Brien, Gerard Clarke, Timothy G Dinan, John F Cryan, Brendan T Griffin. Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability. The international journal of neuropsychopharmacology. 2013 Nov; 16(10):2259-72. doi: 10.1017/s1461145713000692. [PMID: 23931269]
Hirotoshi Sato, Chihiro Ito, Manabu Tashiro, Kotaro Hiraoka, Katsuhiko Shibuya, Yoshihito Funaki, Ren Iwata, Hiroo Matsuoka, Kazuhiko Yanai. Histamine H₁ receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers. Psychopharmacology. 2013 Nov; 230(2):227-34. doi: 10.1007/s00213-013-3146-1. [PMID: 23728612]
J M Quimby, K F Lunn. Mirtazapine as an appetite stimulant and anti-emetic in cats with chronic kidney disease: a masked placebo-controlled crossover clinical trial. Veterinary journal (London, England : 1997). 2013 Sep; 197(3):651-5. doi: 10.1016/j.tvjl.2013.05.048. [PMID: 23838205]
Zsófia Bognár, Gabriella Vonyik, Gábor Gazdag. [Antidepressant treatment associated hyponatremia -- case report]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. 2013 Sep; 15(3):177-80. doi: NULL. [PMID: 24108183]
Shoetsu Chiba, Toru Ikawa, Hiroshi Takeshita, Sanae Kanno, Tomonori Nagai, Meri Takada, Toshiji Mukai, Michael F Wempe. Human organic cation transporter 2 (hOCT2): Inhibitor studies using S2-hOCT2 cells. Toxicology. 2013 Aug; 310(?):98-103. doi: 10.1016/j.tox.2013.06.001. [PMID: 23770354]
Marco Iannetta, Anna Bellizzi, Sara Lo Menzo, Elena Anzivino, Alessandra D'Abramo, Alessandra Oliva, Claudia D'Agostino, Gabriella d'Ettorre, Valeria Pietropaolo, Vincenzo Vullo, Maria Rosa Ciardi. HIV-associated progressive multifocal leukoencephalopathy: longitudinal study of JC virus non-coding control region rearrangements and host immunity. Journal of neurovirology. 2013 Jun; 19(3):274-9. doi: 10.1007/s13365-013-0167-9. [PMID: 23715894]
M Deuschle, M Gilles, B Scharnholz, F Lederbogen, U E Lang, R Hellweg. Changes of serum concentrations of brain-derived neurotrophic factor (BDNF) during treatment with venlafaxine and mirtazapine: role of medication and response to treatment. Pharmacopsychiatry. 2013 Mar; 46(2):54-8. doi: 10.1055/s-0032-1321908. [PMID: 22961097]
Claudia Schilling, Maria Gilles, Werner F Blum, Emmerich Daseking, Michael Colla, Bettina Weber-Hamann, Florian Lederbogen, Bertram Krumm, Isabella Heuser, Stefan A Wudy, Daniel Kopf, Michael Deuschle. Leptin plasma concentrations increase during antidepressant treatment with amitriptyline and mirtazapine, but not paroxetine and venlafaxine: leptin resistance mediated by antihistaminergic activity?. Journal of clinical psychopharmacology. 2013 Feb; 33(1):99-103. doi: 10.1097/jcp.0b013e31827cb179. [PMID: 23277262]
Ney Carter Borges, Rafael Eliseo Barrientos-Astigarraga, Carlos Eduardo Sverdloff, José Luiz Donato, Patricia Moreno, Leila Felix, Paulo Alexandre Rebelo Galvinas, Ronilson Agnaldo Moreno. A fast, sensitive and simple method for mirtazapine quantification in human plasma by HPLC-ESI-MS/MS. Application to a comparative bioavailability study. Biomedical chromatography : BMC. 2012 Nov; 26(11):1399-407. doi: 10.1002/bmc.2711. [PMID: 22345050]
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