pheneticillin (BioDeep_00000734597)

   


代谢物信息卡片


pheneticillin

化学式: C17H20N2O5S (364.10928700000005)
中文名称: 非奈西林
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(=O)NC1C2N(C1=O)C(C(S2)(C)C)C(=O)O)OC3=CC=CC=C3
InChI: InChI=1S/C17H20N2O5S/c1-9(24-10-7-5-4-6-8-10)13(20)18-11-14(21)19-12(16(22)23)17(2,3)25-15(11)19/h4-9,11-12,15H,1-3H3,(H,18,20)(H,22,23)/t9?,11-,12+,15-/m1/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01C - Beta-lactam antibacterials, penicillins > J01CE - Beta-lactamase sensitive penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

1 个代谢物同义名

pheneticillin



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • Kazuhiro Hatano. [Simultaneous determination of five penicillins in muscle, liver and kidney from slaughtered animals using liquid chromatography coupled with electrospray ionization tandem mass spectrometry]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan. 2003 Feb; 44(1):1-6. doi: 10.3358/shokueishi.44.1. [PMID: 12749189]
  • E J Vollaard, H A Clasener, A J van Griethuysen, A J Janssen, A H Sanders-Reijmers, N F Muller, P J Huige. Influence of cefaclor, phenethicillin, co-trimoxazole and doxycycline on colonization resistance in healthy volunteers. The Journal of antimicrobial chemotherapy. 1988 Nov; 22(5):747-58. doi: 10.1093/jac/22.5.747. [PMID: 3145269]
  • A D Watson, D R Emslie, I C Martin, J R Egerton. Effect of ingesta on systemic availability of penicillins administered orally in dogs. Journal of veterinary pharmacology and therapeutics. 1986 Jun; 9(2):140-9. doi: 10.1111/j.1365-2885.1986.tb00023.x. [PMID: 3088288]
  • D Overbosch, H Mattie, R van Furth. Comparative pharmacodynamics and clinical pharmacokinetics of phenoxymethylpenicillin and pheneticillin. British journal of clinical pharmacology. 1985 May; 19(5):657-68. doi: 10.1111/j.1365-2125.1985.tb02693.x. [PMID: 3924086]
  • O P ROBINSON. THE EFFECT OF PROBENECID IN DELAYING THE URINARY EXCRETIONS OF THE NEW PENICILLINS DERIVED FROM 6-AMINOPENICILLANIC ACID. The British journal of clinical practice. 1964 Oct; 18(?):593-600. doi: NULL. [PMID: 14209348]
  • J A GROENROOS. ANTISTAPHYLOCOCCAL ACTIVITY OF ERYTHROMYCIN BASE IN COMBINATION WITH PENICILLIN G, PENICILLIN V AND PHENETHICILLIN AND THAT OF SERUM FOLLOWING ADMINISTRATION OF PROPIONYL ERYTHROMYCIN LAURYL SULFATE--PENICILLIN V COMBINATIONS. Current therapeutic research, clinical and experimental. 1964 Jul; 6(?):483-90. doi: NULL. [PMID: 14203279]
  • S C PAL, B G RAY. METHICILLIN-RESISTANT STAPHYLOCOCCI. Journal of the Indian Medical Association. 1964 Jun; 42(?):512-7. doi: NULL. [PMID: 14171278]
  • G MOESSNER, H MAURER. [THE NEW SEMISYNTHETIC PENICILLINS. A COMPARATIVE ANALYSIS OF THEIR PROPERTIES WITH EXPERIMENTAL FINDINGS]. Medizinische Klinik. 1964 Jan; 59(?):102-7. doi: NULL. [PMID: 14162598]
  • H VANDERHAEGHE, G PARMENTIER, E EVRARD. IDENTIFICATION OF P-HYDROXYPHENOXYMETHYL PENICILLIN AS A METABOLITE OF PHENOXYMETHYL PENICILLIN. Nature. 1963 Nov; 200(?):891. doi: 10.1038/200891a0. [PMID: 14096070]
  • J M BOND, M BARBER, J W LIGHTBOWN, P M WATERWORTH. A COMPARISON OF FOUR PHENOXYPENICILLINS. British medical journal. 1963 Oct; 2(5363):956-61. doi: 10.1136/bmj.2.5363.956. [PMID: 14056922]
  • A H DUBE. A comparison of serum concentrations produced by phenethicillin, penicillin V, and penicillin G after oral and intramuscular administration in geriatric patients. Antibiotics & chemotherapy (Northfield, Ill.). 1961 Oct; 11(?):625-9. doi: NULL. [PMID: 13888028]
  • G ELLEMANN, C JORGENSEN, A C THOMSEN. [The antibacterial activity of the plasma after peroral administration of phenoxcillin and phenethicillin]. Ugeskrift for laeger. 1961 Aug; 123(?):1127-31. doi: NULL. [PMID: 13726407]
  • W J MARTIN, D R NICHOLS. Penicillin V and phenethicillin potassium in serum: comparison of concentrations and of antibacterial effects. Proceedings of the staff meetings. Mayo Clinic. 1960 Sep; 35(?):577-84. doi: NULL. [PMID: 13767422]