Magnesium citrate (BioDeep_00000733339)

   


代谢物信息卡片


Magnesium citrate

化学式: C12H10Mg3O14 (449.96220600000004)
中文名称: 无水柠檬酸镁, 柠檬酸镁
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Mg+2].[Mg+2].[Mg+2]
InChI: /q

描述信息

B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05C - Irrigating solutions > B05CB - Salt solutions
A - Alimentary tract and metabolism > A06 - Drugs for constipation > A06A - Drugs for constipation > A06AD - Osmotically acting laxatives
A - Alimentary tract and metabolism > A12 - Mineral supplements > A12C - Other mineral supplements > A12CC - Magnesium
D005765 - Gastrointestinal Agents > D002400 - Cathartics

同义名列表

1 个代谢物同义名

Magnesium citrate



数据库引用编号

9 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Joëlle C Schutten, Peter J Joris, Iris Groendijk, Coby Eelderink, Dion Groothof, Yvonne van der Veen, Ralf Westerhuis, Frans Goorman, Richard M Danel, Martin H de Borst, Stephan J L Bakker. Effects of Magnesium Citrate, Magnesium Oxide, and Magnesium Sulfate Supplementation on Arterial Stiffness: A Randomized, Double-Blind, Placebo-Controlled Intervention Trial. Journal of the American Heart Association. 2022 03; 11(6):e021783. doi: 10.1161/jaha.121.021783. [PMID: 35253448]
  • Renáta Bor, Mária Matuz, Anna Fabián, Zoltán Szepes, Kata Szántó, Klaudia Farkas, Mariann Rutka, Ágnes Milassin, Daniella Pigniczki, Anita Bálint, Tibor Tóth, Tamás Molnár. Efficacy, tolerability and safety of a split-dose bowel cleansing regimen of magnesium citrate with sodium picosulfate - a phase IV clinical observational study. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva. 2021 Sep; 113(9):635-642. doi: 10.17235/reed.2020.7073/2020. [PMID: 33371690]
  • Kseniia Afitska, Julia Clavel, Klaus Kisters, Jürgen Vormann, Tanja Werner. Magnesium citrate supplementation decreased blood pressure and HbA1c in normomagnesemic subjects with metabolic syndrome: a 12-week, placebo-controlled, double-blinded pilot trial. Magnesium research. 2021 Aug; 34(3):130-139. doi: 10.1684/mrh.2021.0489. [PMID: 34859788]
  • Tommaso Cai, Daniele Tiscione, Marco Puglisi, Gianni Malossini, Lorenzo Ruggera, Paolo Verze, Davide Arcaniolo, Alessandro Palmieri. Phyllanthus niruri and Chrysanthellum americanum in association with potassium and magnesium citrates are able to prevent symptomatic episode in patients affected by recurrent urinary stones: A prospective study. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. 2021 Jun; 93(2):184-188. doi: 10.4081/aiua.2021.2.184. [PMID: 34286553]
  • Tanja Werner, Martin Kolisek, Jürgen Vormann, Ivana Pilchova, Marian Grendar, Eva Struharnanska, Michal Cibulka. Assessment of bioavailability of Mg from Mg citrate and Mg oxide by measuring urinary excretion in Mg-saturated subjects. Magnesium research. 2019 Aug; 32(3):63-71. doi: 10.1684/mrh.2019.0457. [PMID: 32162607]
  • Henry Quiñones, Tamim Hamdi, Khashayar Sakhaee, Andreas Pasch, Orson W Moe, Charles Y C Pak. Control of metabolic predisposition to cardiovascular complications of chronic kidney disease by effervescent calcium magnesium citrate: a feasibility study. Journal of nephrology. 2019 Feb; 32(1):93-100. doi: 10.1007/s40620-018-0559-2. [PMID: 30465137]
  • Zhihui Yao, Yang Xu, Weidong Ma, Xin-Yuan Sun, Shan Jia, Yang Zheng, Xiaohuan Liu, Yajie Fan, Congxia Wang. Magnesium Citrate Protects Against Vascular Calcification in an Adenine-induced Chronic Renal Failure Rat Model. Journal of cardiovascular pharmacology. 2018 12; 72(6):270-276. doi: 10.1097/fjc.0000000000000590. [PMID: 29738375]
  • Syed Rizwan Bokhari, Ravi Siriki, Federico J Teran, Vecihi Batuman. Fatal Hypermagnesemia Due to Laxative Use. The American journal of the medical sciences. 2018 Apr; 355(4):390-395. doi: 10.1016/j.amjms.2017.08.013. [PMID: 29661354]
  • Elisabeth M H Mathus-Vliegen, Karin van der Vliet, Inge J Wignand-van der Storm, John S Stadwijk. Efficacy and Safety of Sodium Picosulfate/Magnesium Citrate for Bowel Preparation in a Physically Disabled Outpatient Population: A Randomized, Endoscopist-Blinded Comparison With Ascorbic Acid-Enriched Polyethylene Glycol Solution Plus Bisacodyl (The PICO-MOVI Study). Diseases of the colon and rectum. 2018 Feb; 61(2):239-249. doi: 10.1097/dcr.0000000000000956. [PMID: 29337780]
  • Michele Barbera, Andreas Tsirgiotis, Mauro Barbera, Quintino Paola. The importance of citrates in treatment and prophylaxis of calcium oxalate urinary stones. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. 2016 Dec; 88(4):343-344. doi: 10.4081/aiua.2016.4.343. [PMID: 28073210]
  • Andrea Tasca, Ciro Ammendola. [Nephrolithiasis: metabolic defects and terapeutic implications]. Urologia. 2014 Jan; 81(1):1-11. doi: 10.5301/uro.5000058. [PMID: 24744215]
  • Maria Bullarbo, Natalia Ödman, Axel Nestler, Thorkild Nielsen, Martin Kolisek, Jürgen Vormann, Ragnar Rylander. Magnesium supplementation to prevent high blood pressure in pregnancy: a randomised placebo control trial. Archives of gynecology and obstetrics. 2013 Dec; 288(6):1269-74. doi: 10.1007/s00404-013-2900-2. [PMID: 23715924]
  • C Monet, E Richard, S Missonnier, L Rebouissoux, B Llanas, J Harambat. [Secondary hyperoxaluria and nephrocalcinosis due to ethylene glycol poisoning]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. 2013 Aug; 20(8):863-6. doi: 10.1016/j.arcped.2013.05.011. [PMID: 23827374]
  • A Ghanouni, S G Smith, S Halligan, S A Taylor, A Plumb, D Boone, C von Wagner. An interview study analysing patients' experiences and perceptions of non-laxative or full-laxative preparation with faecal tagging prior to CT colonography. Clinical radiology. 2013 May; 68(5):472-8. doi: 10.1016/j.crad.2012.10.012. [PMID: 23265916]
  • Toru Sugihara, Hideo Yasunaga, Hiromasa Horiguchi, Tetsuya Fujimura, Hiroaki Nishimatsu, Kazuhiko Ohe, Shinya Matsuda, Kiyohide Fushimi, Michael W Kattan, Yukio Homma. Does mechanical bowel preparation improve quality of laparoscopic nephrectomy? Propensity score-matched analysis in Japanese series. Urology. 2013 Jan; 81(1):74-9. doi: 10.1016/j.urology.2012.09.032. [PMID: 23273073]
  • Selda Bagis, Mehmet Karabiber, Ismet As, Lülüfer Tamer, Canan Erdogan, Ayçe Atalay. Is magnesium citrate treatment effective on pain, clinical parameters and functional status in patients with fibromyalgia?. Rheumatology international. 2013 Jan; 33(1):167-72. doi: 10.1007/s00296-011-2334-8. [PMID: 22271372]
  • Michael Shechter, Tomer Saad, Alon Shechter, Nira Koren-Morag, Burton B Silver, Shlomi Matetzky. Comparison of magnesium status using X-ray dispersion analysis following magnesium oxide and magnesium citrate treatment of healthy subjects. Magnesium research. 2012 Mar; 25(1):28-39. doi: 10.1684/mrh.2012.0305. [PMID: 22433473]
  • Wilhelm Jahnen-Dechent, Markus Ketteler. Magnesium basics. Clinical kidney journal. 2012 Feb; 5(Suppl 1):i3-i14. doi: 10.1093/ndtplus/sfr163. [PMID: 26069819]
  • Sara A Chacko, James Sul, Yiqing Song, Xinmin Li, James LeBlanc, Yuko You, Anthony Butch, Simin Liu. Magnesium supplementation, metabolic and inflammatory markers, and global genomic and proteomic profiling: a randomized, double-blind, controlled, crossover trial in overweight individuals. The American journal of clinical nutrition. 2011 Feb; 93(2):463-73. doi: 10.3945/ajcn.110.002949. [PMID: 21159786]
  • M Watanabe, M Murakami, K Nakao, T Asahara, K Nomoto, A Tsunoda. Randomized clinical trial of the influence of mechanical bowel preparation on faecal microflora in patients undergoing colonic cancer resection. The British journal of surgery. 2010 Dec; 97(12):1791-7. doi: 10.1002/bjs.7253. [PMID: 20799286]
  • Caroline Nyberg, Jakob Hendel, Ole H Nielsen. The safety of osmotically acting cathartics in colonic cleansing. Nature reviews. Gastroenterology & hepatology. 2010 Oct; 7(10):557-64. doi: 10.1038/nrgastro.2010.136. [PMID: 20736921]
  • Toshihiro Kikuchi, Seiichiro Kumakura, Yutaka Tanabe. Perioperative management for a patient with hypermagnesemia-induced shock with perforative peritonitis. Journal of anesthesia. 2010 Jun; 24(3):479-81. doi: 10.1007/s00540-010-0909-2. [PMID: 20333415]
  • Minita Patel, Megan O Schimpf, David M O'Sullivan, Christine A LaSala. The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial. American journal of obstetrics and gynecology. 2010 May; 202(5):479.e1-5. doi: 10.1016/j.ajog.2010.01.003. [PMID: 20207340]
  • Hasan Aydin, Oğuzhan Deyneli, Dilek Yavuz, Hülya Gözü, Nilgün Mutlu, Işik Kaygusuz, Sema Akalin. Short-term oral magnesium supplementation suppresses bone turnover in postmenopausal osteoporotic women. Biological trace element research. 2010 Feb; 133(2):136-43. doi: 10.1007/s12011-009-8416-8. [PMID: 19488681]
  • Soon Ho Yoon, Se Hyung Kim, Sang Gyun Kim, Soo Jin Kim, Jeong Min Lee, Jae Young Lee, Joon Koo Han, Byung Ihn Choi. Comparison study of different bowel preparation regimens and different fecal-tagging agents on tagging efficacy, patients' compliance, and diagnostic performance of computed tomographic colonography: preliminary study. Journal of computer assisted tomography. 2009 Sep; 33(5):657-65. doi: 10.1097/rct.0b013e3181926570. [PMID: 19820488]
  • Ingerid Herstad Nygaard, Annelill Valbø, Sigrid Vingerhagen Pethick, Thomas Bøhmer. Does oral magnesium substitution relieve pregnancy-induced leg cramps?. European journal of obstetrics, gynecology, and reproductive biology. 2008 Nov; 141(1):23-6. doi: 10.1016/j.ejogrb.2008.07.005. [PMID: 18768245]
  • Faruk Turgut, Mehmet Kanbay, Melike Rusen Metin, Ebru Uz, Ali Akcay, Adrian Covic. Magnesium supplementation helps to improve carotid intima media thickness in patients on hemodialysis. International urology and nephrology. 2008; 40(4):1075-82. doi: 10.1007/s11255-008-9410-3. [PMID: 18568412]
  • Stuart A Taylor, Andrew Slater, David N Burling, Emily Tam, Rebecca Greenhalgh, Louise Gartner, Julia Scarth, Robert Pearce, Paul Bassett, Steve Halligan. CT colonography: optimisation, diagnostic performance and patient acceptability of reduced-laxative regimens using barium-based faecal tagging. European radiology. 2008 Jan; 18(1):32-42. doi: 10.1007/s00330-007-0631-0. [PMID: 17404739]
  • G Ducarme, C Davitian, M Uzan, X Belenfant, C Poncelet. [Pregnancy in a patient with Gitelman syndrome: a case report and review of literature]. Journal de gynecologie, obstetrique et biologie de la reproduction. 2007 May; 36(3):310-3. doi: 10.1016/j.jgyn.2006.10.004. [PMID: 17466223]
  • Abraham H Dachman, Damien O Dawson, Philippe Lefere, Hiro Yoshida, Nasreen U Khan, Nicole Cipriani, David T Rubin. Comparison of routine and unprepped CT colonography augmented by low fiber diet and stool tagging: a pilot study. Abdominal imaging. 2007 Jan; 32(1):96-104. doi: 10.1007/s00261-006-9044-9. [PMID: 16969601]
  • Iffet Bircan, Doga Turkkahraman, Oguz Dursun, Gulay Karaguzel. Successful management of primary hypomagnesaemia with high-dose oral magnesium citrate: a case report. Acta paediatrica (Oslo, Norway : 1992). 2006 Dec; 95(12):1697-9. doi: 10.1080/08035250600750098. [PMID: 17129989]
  • Mohammad F El-Baba, Mary Padilla, Carmela Houston, Shailender Madani, Chuan-Hao Lin, Ronald Thomas, Vasundhara Tolia. A prospective study comparing oral sodium phosphate solution to a bowel cleansing preparation with nutrition food package in children. Journal of pediatric gastroenterology and nutrition. 2006 Feb; 42(2):174-7. doi: 10.1097/01.mpg.0000189353.40419.31. [PMID: 16456411]
  • Sachiko Onishi, Shunpei Yoshino. Cathartic-induced fatal hypermagnesemia in the elderly. Internal medicine (Tokyo, Japan). 2006; 45(4):207-10. doi: 10.2169/internalmedicine.45.1482. [PMID: 16543690]
  • S Gryspeerdt, P Lefere, M Herman, R Deman, L Rutgeerts, G Ghillebert, F Baert, M Baekelandt, B Van Holsbeeck. CT colonography with fecal tagging after incomplete colonoscopy. European radiology. 2005 Jun; 15(6):1192-202. doi: 10.1007/s00330-005-2644-x. [PMID: 15702335]
  • Philippe Lefere, Stefaan Gryspeerdt, Jesse Marrannes, Marc Baekelandt, Bartel Van Holsbeeck. CT colonography after fecal tagging with a reduced cathartic cleansing and a reduced volume of barium. AJR. American journal of roentgenology. 2005 Jun; 184(6):1836-42. doi: 10.2214/ajr.184.6.01841836. [PMID: 15908539]
  • Makoto Kontani, Akinori Hara, Shinji Ohta, Takayuki Ikeda. Hypermagnesemia induced by massive cathartic ingestion in an elderly woman without pre-existing renal dysfunction. Internal medicine (Tokyo, Japan). 2005 May; 44(5):448-52. doi: 10.2169/internalmedicine.44.448. [PMID: 15942092]
  • Lionel Dumont, Christopher Lysakowski, Martin R Tramèr, Jean-Daniel Junod, Chahé Mardirosoff, Edömer Tassonyi, Bengt Kayser. Magnesium for the prevention and treatment of acute mountain sickness. Clinical science (London, England : 1979). 2004 Mar; 106(3):269-77. doi: 10.1042/cs20030187. [PMID: 14572305]
  • Olga Bede, Andrea Surányi, Katalin Pintér, Mária Szlávik, Kálmán Gyurkovits. Urinary magnesium excretion in asthmatic children receiving magnesium supplementation: a randomized, placebo-controlled, double-blind study. Magnesium research. 2003 Dec; 16(4):262-70. doi: NULL. [PMID: 14979636]
  • Ann F Walker, Georgios Marakis, Samantha Christie, Martyn Byng. Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study. Magnesium research. 2003 Sep; 16(3):183-91. doi: NULL. [PMID: 14596323]
  • P O Schwille, A Schmiedl, R Schwille, P Brunner, H Kissler, R Cesnjevar, H Gepp. Media calcification, low erythrocyte magnesium, altered plasma magnesium, and calcium homeostasis following grafting of the thoracic aorta to the infrarenal aorta in the rat--differential preventive effects of long-term oral magnesium supplementation alone and in combination with alkali. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2003 Mar; 57(2):88-97. doi: 10.1016/s0753-3322(02)00343-8. [PMID: 12842494]
  • Philippe A Lefere, Stefaan S Gryspeerdt, Jef Dewyspelaere, Marc Baekelandt, Bartel G Van Holsbeeck. Dietary fecal tagging as a cleansing method before CT colonography: initial results polyp detection and patient acceptance. Radiology. 2002 Aug; 224(2):393-403. doi: 10.1148/radiol.2241011222. [PMID: 12147834]
  • Maria Carmina Garcia, Ryland P Byrd, Thomas M Roy. Lethal iatrogenic hypermagnesemia. Tennessee medicine : journal of the Tennessee Medical Association. 2002 Aug; 95(8):334-6. doi: NULL. [PMID: 12174756]
  • A M Freitas, N Schor, M A Boim. The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation. BJU international. 2002 Jun; 89(9):829-34. doi: 10.1046/j.1464-410x.2002.02794.x. [PMID: 12010223]
  • A Schmiedl, P O Schwille, E Bonucci, T Seitz, R M Schwille, M Manoharan. Renal cortical calcification in syngeneic intact rats and those receiving an infrarenal thoracic aortic graft: possible etiological roles of endothelin, nitrate and minerals, and different preventive effects of long-term oral treatment with magnesium, citrate and alkali-containing preparations. Urological research. 2001 08; 29(4):229-37. doi: 10.1007/s002400100191. [PMID: 11585277]
  • R Rylander, Y Mégevand, B Lasserre, W Amstutz, S Granbom. Moderate alcohol consumption and urinary excretion of magnesium and calcium. Scandinavian journal of clinical and laboratory investigation. 2001; 61(5):401-5. doi: 10.1080/003655101316911459. [PMID: 11569488]
  • N Cohen, I Alon, D Almoznino-Sarafian, R Zaidenstein, J Weissgarten, O Gorelik, S Berman, D Modai, A Golik. Metabolic and clinical effects of oral magnesium supplementation in furosemide-treated patients with severe congestive heart failure. Clinical cardiology. 2000 Jun; 23(6):433-6. doi: 10.1002/clc.4960230611. [PMID: 10875034]
  • J R Schelling. Fatal hypermagnesemia. Clinical nephrology. 2000 Jan; 53(1):61-5. doi: NULL. [PMID: 10661484]
  • D E Cole, S W Kooh, R Vieth. Primary infantile hypomagnesaemia: outcome after 21 years and treatment with continuous nocturnal nasogastric magnesium infusion. European journal of pediatrics. 2000 Jan; 159(1-2):38-43. doi: 10.1007/s004310050007. [PMID: 10653327]
  • M Fujiwara, I Okayasu, M Oritsu, J Komatsu, M Yoshitsugu, Y Katoh, T Bandoh, H Toyoshima, Y Kase, K Sugihara, J Kanno, Y Hayashi. Significant increase in prostaglandin E-main urinary metabolite by laxative administration: comparison with ulcerative colitis. Digestion. 2000; 61(3):201-6. doi: 10.1159/000007758. [PMID: 10773726]
  • T S Dharmarajan, B Patel, N Varshneya. Cathartic-induced life threatening hypermagnesemia in a 90-year-old woman with apparent normal renal function. Journal of the American Geriatrics Society. 1999 Aug; 47(8):1039-40. doi: 10.1111/j.1532-5415.1999.tb01309.x. [PMID: 10443875]
  • L A Ruml, C Y Pak. Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1999 Jul; 34(1):107-13. doi: 10.1016/s0272-6386(99)70115-0. [PMID: 10401023]
  • P O Schwille, A Schmiedl, U Herrmann, J Fan, D Gottlieb, M Manoharan, J Wipplinger. Magnesium, citrate, magnesium citrate and magnesium-alkali citrate as modulators of calcium oxalate crystallization in urine: observations in patients with recurrent idiopathic calcium urolithiasis. Urological research. 1999 Apr; 27(2):117-26. doi: 10.1007/s002400050097. [PMID: 10424393]
  • A Schmiedl, P O Schwille, B Bergé, M Markovic, O Dvorak. Reappraisal of the quantity and nature of renal calcifications and mineral metabolism in the magnesium-deficient rat. Effects of treatment with potassium citrate or the combination magnesium citrate and potassium citrate. Urologia internationalis. 1998; 61(2):76-85. doi: 10.1159/000030293. [PMID: 9873245]
  • S P Nielsen. Free and protein-bound magnesium in normal human plasma determined by ultracentrifugation and ultrafiltration. Scandinavian journal of clinical and laboratory investigation. 1969 May; 23(3):219-25. doi: 10.3109/00365516909077652. [PMID: 5383308]