Reglan (BioDeep_00000732720)
代谢物信息卡片
metoclopramide hydrochloride
化学式: C14H25Cl2N3O3 (353.127288)
中文名称: 盐酸甲氧氯普胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.O.Cl
InChI: 1H
描述信息
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent
D005765 - Gastrointestinal Agents > D000932 - Antiemetics
D002491 - Central Nervous System Agents
同义名列表
2 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:6899
- KEGGdrug: D05008
- PubChem: 441347
- ChEMBL: CHEMBL1200940
- MeSH: Metoclopramide
- CAS: 54143-57-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Juste Baranauskaite, Meryem Aydin, Burcu Uner, Cetin Tas. Formulation of Metoclopramide Hydrochloride-Loaded Lipid Carriers by QbD Approach for Combating Nausea: Safety and Bioavailability Evaluation in New Zealand Rabbit.
AAPS PharmSciTech.
2024 Apr; 25(4):73. doi:
10.1208/s12249-024-02791-0. [PMID: 38575825] - Hyun-Ku Lee, Chul Jin, Seungwon Kwon, Bo-Hyoung Jang, Jin Pyeong Jeon, Ye-Seul Lee, Seung-Bo Yang, Woo-Sang Jung, Sang-Kwan Moon, Ki-Ho Cho. Treatment of nausea and vomiting associated with cerebellar infarction using the traditional herbal medicines banhabaekchulcheonma-tang and oryeong-san: Two case reports (CARE-complaint).
Explore (New York, N.Y.).
2023 Jan; 19(1):141-146. doi:
10.1016/j.explore.2021.11.011. [PMID: 34911662] - Die Wang, Changyan Zi, Baocheng Zhang, Baojia Wang, Tao Chen, Long Wang, Yongxiang Gao. Effectiveness and safety of metoclopramide in treatment of intractable hiccup: a protocol of systematic review and meta-analysis.
BMJ open.
2022 10; 12(10):e059887. doi:
10.1136/bmjopen-2021-059887. [PMID: 36202584] - A A Sher, A Iqbal, M Adil, S Ullah, S Bawazeer, M K Binmahri, L Z Zamil, M Irfan. GC-MS analysis of organic fractions of Chrozophora tinctoria (L.) A.Juss. and their prokinetic propensity in animal models.
Brazilian journal of biology = Revista brasleira de biologia.
2022; 84(?):e260566. doi:
10.1590/1519-6984.260566. [PMID: 35613215] - Flavia Storelli, Olena Anoshchenko, Jashvant D Unadkat. Successful Prediction of Human Steady-State Unbound Brain-to-Plasma Concentration Ratio of P-gp Substrates Using the Proteomics-Informed Relative Expression Factor Approach.
Clinical pharmacology and therapeutics.
2021 08; 110(2):432-442. doi:
10.1002/cpt.2227. [PMID: 33675056] - Akbar Dorgalaleh, Ali Dabbagh, Shadi Tabibian, Mehran Bahraini, Hassan Rafieemehr. Persistent hiccups in a patient with mild congenital factor V deficiency and COVID-19; clinical and laboratory finding of a rare bleeding disorder.
International journal of laboratory hematology.
2021 04; 43(2):e87-e88. doi:
10.1111/ijlh.13385. [PMID: 33174336] - Martin Bauer, Sandra Barna, Matthias Blaickner, Konstantin Prosenz, Karsten Bamminger, Verena Pichler, Nicolas Tournier, Marcus Hacker, Markus Zeitlinger, Georgios Karanikas, Oliver Langer. Human Biodistribution and Radiation Dosimetry of the P-Glycoprotein Radiotracer [11C]Metoclopramide.
Molecular imaging and biology.
2021 04; 23(2):180-185. doi:
10.1007/s11307-021-01582-4. [PMID: 33481175] - Yifan Chen, Min Zhang, Xinghao Ji, Jinjin Zhao, Shuang Qin, Yinghua Ji, Ruijuan Fan, Yanting Liu, Ping Lu. The anti-cancer effect of metoclopramide on triple-negative breast cancer cells.
Die Pharmazie.
2021 04; 76(4):172-174. doi:
10.1691/ph.2021.0977. [PMID: 33849703] - Martin Bauer, Karsten Bamminger, Verena Pichler, Maria Weber, Simon Binder, Alexandra Maier-Salamon, Ammar Tahir, Walter Jäger, Helmuth Haslacher, Nicolas Tournier, Marcus Hacker, Markus Zeitlinger, Oliver Langer. Impaired Clearance From the Brain Increases the Brain Exposure to Metoclopramide in Elderly Subjects.
Clinical pharmacology and therapeutics.
2021 03; 109(3):754-761. doi:
10.1002/cpt.2052. [PMID: 32966590] - Irene Hernández-Lozano, Severin Mairinger, Michael Sauberer, Johann Stanek, Thomas Filip, Thomas Wanek, Giuliano Ciarimboli, Nicolas Tournier, Oliver Langer. Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
Pharmaceutical research.
2021 Jan; 38(1):127-140. doi:
10.1007/s11095-021-03002-2. [PMID: 33559045] - Kun-Siang Huang, Bo-Lin Pan, Wei-An Lai, Pin-Jie Bin, Yao-Hsu Yang, Chia-Pei Chou. Could prokinetic agents protect long-term nasogastric tube-dependent patients from being hospitalized for pneumonia? A nationwide population-based case-crossover study.
PloS one.
2021; 16(4):e0249645. doi:
10.1371/journal.pone.0249645. [PMID: 33819293] - Shufan Ge, Susan R Mendley, Jacqueline G Gerhart, Chiara Melloni, Christoph P Hornik, Janice E Sullivan, Andrew Atz, Paula Delmore, Adriana Tremoulet, Barrie Harper, Elizabeth Payne, Susan Lin, Jinson Erinjeri, Michael Cohen-Wolkowiez, Daniel Gonzalez. Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents.
Clinical and translational science.
2020 11; 13(6):1189-1198. doi:
10.1111/cts.12803. [PMID: 32324313] - Jung-Woo Bae, Kyung-Yul Oh, So-Jung Yoon, Hyo-Bin Shin, Eui Hyun Jung, Chang-Keun Cho, Chang Woo Lim, Pureum Kang, Chang-Ik Choi, Choon-Gon Jang, Seok-Yong Lee, Yun Jeong Lee. Effects of CYP2D6 genetic polymorphism on the pharmacokinetics of metoclopramide.
Archives of pharmacal research.
2020 Nov; 43(11):1207-1213. doi:
10.1007/s12272-020-01293-4. [PMID: 33247397] - Iram Kaukab, Syed Nisar Hussain Shah, Zelal Jaber Kharaba, Manal Ali Buabeid, Yaseen Abd Alfoteih, Ghulam Murtaza. Effect of clarithromycin pre-treatment on the pharmacokinetics of metoclopramide after their simultaneous oral intake.
Expert opinion on drug metabolism & toxicology.
2020 Aug; 16(8):735-740. doi:
10.1080/17425255.2020.1779699. [PMID: 32524862] - Viktoria Zoufal, Severin Mairinger, Mirjam Brackhan, Markus Krohn, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Wanek, Nicolas Tournier, Martin Bauer, Jens Pahnke, Oliver Langer. Imaging P-Glycoprotein Induction at the Blood-Brain Barrier of a β-Amyloidosis Mouse Model with 11C-Metoclopramide PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2020 07; 61(7):1050-1057. doi:
10.2967/jnumed.119.237198. [PMID: 31806767] - Julien Wils, Céline Duparc, Anne-Françoise Cailleux, Antoine-Guy Lopez, Caroline Guiheneuf, Isabelle Boutelet, Hadrien-Gaël Boyer, Christophe Dubessy, Saloua Cherifi, Bruno Cauliez, Françoise Gobet, Guillaume Defortescu, Jean-François Ménard, Estelle Louiset, Hervé Lefebvre. The neuropeptide substance P regulates aldosterone secretion in human adrenals.
Nature communications.
2020 05; 11(1):2673. doi:
10.1038/s41467-020-16470-8. [PMID: 32471973] - Siew Cheng Foong, May Loong Tan, Wai Cheng Foong, Lisa A Marasco, Jacqueline J Ho, Joo Howe Ong. Oral galactagogues (natural therapies or drugs) for increasing breast milk production in mothers of non-hospitalised term infants.
The Cochrane database of systematic reviews.
2020 05; 5(?):CD011505. doi:
10.1002/14651858.cd011505.pub2. [PMID: 32421208] - Amir Reza Naemi, Vahid Kashanitabar, Alireza Kamali, Ashkan Shiva. Comparison of the Effects of Haloperidol, Metoclopramide, Dexmedetomidine and Ginger on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy.
Journal of medicine and life.
2020 Apr; 13(2):206-210. doi:
10.25122/jml-2019-0070. [PMID: 32742515] - Beata Irena Cejko, Sławomir Krejszeff, Sylwia Judycka, Katarzyna Targońska, Dariusz Kucharczyk. Effect of different treatment agents and post-treatment latency times on spermiation stimulation of northern pike (Esox lucius) under controlled conditions.
Theriogenology.
2020 Jan; 142(?):260-267. doi:
10.1016/j.theriogenology.2019.10.035. [PMID: 31711700] - Cecilia Nwadiuto Amadi, Wisdom Izuchukwu Nwachukwu. The effects of oral administration of Cola nitida on the pharmacokinetic profile of metoclopramide in rabbits.
BMC pharmacology & toxicology.
2020 01; 21(1):4. doi:
10.1186/s40360-019-0379-6. [PMID: 31907041] - Mustafa Bilici, M Utku Badak, Adem Zengin, Zekiye Suludere, Nahit Aktas. Synthesis of magnetic halloysite nanotube-based molecularly imprinted polymers for sensitive spectrophotometric detection of metoclopramide in urine samples.
Materials science & engineering. C, Materials for biological applications.
2020 Jan; 106(?):110223. doi:
10.1016/j.msec.2019.110223. [PMID: 31753383] - Iram Kaukab, Syed Nisar Hussain Shah, Muhammad Asad Abrar, Naveed Anwer, Ghulam Murtaza. Influence of Rifampicin Pre-treatment on the In vivo Pharmacokinetics of Metoclopramide in Pakistani Healthy Volunteers Following Concurrent Oral Administration.
Current drug metabolism.
2020; 21(4):301-306. doi:
10.2174/1389200221666200514132654. [PMID: 32407272] - Ahmad Al-Saffar, Hans Lennernäs, Per M Hellström. Gastroparesis, metoclopramide, and tardive dyskinesia: Risk revisited.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
2019 11; 31(11):e13617. doi:
10.1111/nmo.13617. [PMID: 31050085] - Selen Gur-Ozmen, Ruhan Karahan-Ozcan. Factors Associated with Insulin Resistance in Women with Migraine: A Cross-Sectional Study.
Pain medicine (Malden, Mass.).
2019 10; 20(10):2043-2050. doi:
10.1093/pm/pnz055. [PMID: 30938814] - Chao Jiang, Ting Wang, Zheng-Guo Qiu, Bo Chen, Bang-Jiang Fang. Efficacy of metoclopramide for the treatment of acute migraine.
Medicine.
2019 Sep; 98(37):e17065. doi:
10.1097/md.0000000000017065. [PMID: 31517828] - Nicolas Tournier, Martin Bauer, Verena Pichler, Lukas Nics, Eva-Maria Klebermass, Karsten Bamminger, Peter Matzneller, Maria Weber, Rudolf Karch, Fabien Caillé, Sylvain Auvity, Solène Marie, Walter Jäger, Wolfgang Wadsak, Marcus Hacker, Markus Zeitlinger, Oliver Langer. Impact of P-Glycoprotein Function on the Brain Kinetics of the Weak Substrate 11C-Metoclopramide Assessed with PET Imaging in Humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2019 07; 60(7):985-991. doi:
10.2967/jnumed.118.219972. [PMID: 30630940] - Shirin Osouli Tabrizi, Mojgan Mirghafourvand, Abdollah Jannat Dost, Sakineh Mohammad-Alizadeh-Charandabi, Yousef Javadzadeh, Robabe Seyedi. Effect of metoclopramide administration to mothers on neonatal bilirubin and maternal prolactin: a randomized, controlled, clinical trial.
World journal of pediatrics : WJP.
2019 Apr; 15(2):135-142. doi:
10.1007/s12519-018-0217-8. [PMID: 30519818] - Noura H Abd Ellah, Esraa A Ahmed, Rasha B Abd-Ellatief, Marwa F Ali, Asmaa M Zahran, Helal F Hetta. Metoclopramide nanoparticles modulate immune response in a diabetic rat model: association with regulatory T cells and proinflammatory cytokines.
International journal of nanomedicine.
2019; 14(?):2383-2395. doi:
10.2147/ijn.s196842. [PMID: 31040663] - Iram Kaukab, Syed Nisar Hussain Shah, Zelal Kharaba, Ghulam Murtaza, Abubaker Ali Saad, Shakeel Ahmad. Evaluation of Pharmacokinetic Interaction of Cilostazol with Metoclopramide after Oral Administration in Human.
Current drug metabolism.
2019; 20(11):924-928. doi:
10.2174/1389200220666191105115805. [PMID: 31702486] - Bei Hu, Xin Ouyang, Liming Lei, Cheng Sun, Ruibin Chi, Jian Guo, Wenlong Guo, Yanlin Zhang, Yong Li, Daoyong Huang, Huafeng Sun, Zhiqiang Nie, Jieyang Yu, Yuan Zhou, Hao Wang, Jinhe Zhang, Chunbo Chen. Erythromycin versus metoclopramide for post-pyloric spiral nasoenteric tube placement: a randomized non-inferiority trial.
Intensive care medicine.
2018 Dec; 44(12):2174-2182. doi:
10.1007/s00134-018-5466-4. [PMID: 30465070] - Joanna Sikora, Piotr Niezgoda, Malwina Barańska, Katarzyna Buszko, Natalia Skibińska, Wiktor Sroka, Krzysztof Pstrągowski, Jolanta Siller-Matula, Jilma Bernd, Diana Gorog, Eliano Pio Navarese, Michał Piotr Marszałł, Jacek Kubica. METoclopramide Administration as a Strategy to Overcome MORPHine-ticagrelOr Interaction in PatientS with Unstable Angina PectorIS-The METAMORPHOSIS Trial.
Thrombosis and haemostasis.
2018 Dec; 118(12):2126-2133. doi:
10.1055/s-0038-1675605. [PMID: 30453344] - Laura J Henze, Brendan T Griffin, Martin Christiansen, Christoffer Bundgaard, Peter Langguth, René Holm. Exploring gastric emptying rate in minipigs: Effect of food type and pre-dosing of metoclopramide.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2018 Jun; 118(?):183-190. doi:
10.1016/j.ejps.2018.03.017. [PMID: 29559403] - James B Leonard, Kashif M Munir, Hong K Kim. Metoclopramide induced pheochromocytoma crisis.
The American journal of emergency medicine.
2018 Jun; 36(6):1124.e1-1124.e2. doi:
10.1016/j.ajem.2018.03.009. [PMID: 29534916] - Ying Li, Xianpeng Fan, Wanqing Li, Peng Yang, Hui Zhang, Daoquan Tang, Xiaoxin Yin, Jianxu Sun, Aiping Zheng. Metoclopramide nasal spray in vitro evaluation and in vivo pharmacokinetic studies in dogs.
Pharmaceutical development and technology.
2018 Mar; 23(3):275-281. doi:
10.1080/10837450.2017.1316734. [PMID: 28379057] - Gina Della Togna, Brian Gratwicke, Matthew Evans, Lauren Augustine, Han Chia, Ed Bronikowski, James B Murphy, Pierre Comizzoli. Influence of extracellular environment on the motility and structural properties of spermatozoa collected from hormonally stimulated Panamanian Golden Frog (Atelopus zeteki).
Theriogenology.
2018 Mar; 108(?):153-160. doi:
10.1016/j.theriogenology.2017.11.032. [PMID: 29216539] - S K Zhang, W B Gao, Y Liu, H He. [Therapeutic effect of cervical Jiaji electroacupuncture on postoperative intractable hiccup of liver neoplasms].
Zhonghua zhong liu za zhi [Chinese journal of oncology].
2018 Feb; 40(2):138-140. doi:
10.3760/cma.j.issn.0253-3766.2018.02.011. [PMID: 29502375] - Stefanie R Keller, Zsolt Abonyi-Tóth, Norbert Sprenger, Sean C Austin, Brigitta A C Wichert, Annette Liesegang, Christine H Y Oei, Orsolya Balogh, Iris M Reichler. Effect of metoclopramide treatment of bitches during the first week of lactation on serum prolactin concentration, milk composition, and milk yield and on weight gain of their puppies.
American journal of veterinary research.
2018 Feb; 79(2):233-241. doi:
10.2460/ajvr.79.2.233. [PMID: 29359978] - Fabien Caillé, Sébastien Goutal, Solène Marie, Sylvain Auvity, Salvatore Cisternino, Bertrand Kuhnast, Géraldine Pottier, Nicolas Tournier. Positron Emission Tomography Imaging Reveals an Importance of Saturable Liver Uptake Transport for the Pharmacokinetics of Metoclopramide.
Contrast media & molecular imaging.
2018; 2018(?):7310146. doi:
10.1155/2018/7310146. [PMID: 29853808] - Suxian Luan, Meiling Mu, Liangzhi Sun. The mechanism of selfheal extract in treating hyperprolactinemia.
Cancer biomarkers : section A of Disease markers.
2017 Dec; 20(4):575-580. doi:
10.3233/cbm-170454. [PMID: 28946556] - Hannah Kenward, Jonathan Elliott, Terry Lee, Ludovic Pelligand. Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study.
BMC veterinary research.
2017 Aug; 13(1):244. doi:
10.1186/s12917-017-1156-7. [PMID: 28814338] - Yuanyi Wei, Lei La, Lili Wang, Robert Batey, Chunxia Wang, Yuhao Li. Paeoniflorin and liquiritin, two major constituents in Chinese herbal formulas used to treat hyperprolactinemia-associated disorders, inhibits prolactin secretion in prolactinoma cells by different mechanisms.
Journal of ethnopharmacology.
2017 May; 204(?):36-44. doi:
10.1016/j.jep.2017.03.054. [PMID: 28396166] - Ahmed Madisch, Bettina R Vinson, Heba Abdel-Aziz, Olaf Kelber, Karen Nieber, Karin Kraft, Martin Storr. Modulation of gastrointestinal motility beyond metoclopramide and domperidone : Pharmacological and clinical evidence for phytotherapy in functional gastrointestinal disorders.
Wiener medizinische Wochenschrift (1946).
2017 May; 167(7-8):160-168. doi:
10.1007/s10354-017-0557-3. [PMID: 28424994] - Emilie Zingler, Angélica Amorim Amato, Alysson Zanatta, Maria de Fátima Brito Vogt, Miriam da Silva Wanderley, Coríntio Mariani Neto, Alberto Moreno Zaconeta. Lactation Induction in a Commissioned Mother by Surrogacy: Effects on Prolactin Levels, Milk Secretion and Mother Satisfaction.
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia.
2017 Feb; 39(2):86-89. doi:
10.1055/s-0037-1598641. [PMID: 28257588] - Ahmad Khan, Jallat Khan, Muhammad Irfan, Syed Baqir Shyum Naqvi, Gul Majid Khan, Muhammad Harris Shoaib, Rabia Ismail Yousaf, Amjad Khan. Validation and application of high performance liquid chromatographic method for the estimation of metoclopramide hydrochloride in plasma.
Pakistan journal of pharmaceutical sciences.
2017 Jan; 30(1):143-147. doi:
NULL. [PMID: 28603124] - Carsten Stoetzer, Marc Voelker, Thorben Doll, Joerg Heineke, Florian Wegner, Andreas Leffler. Cardiotoxic Antiemetics Metoclopramide and Domperidone Block Cardiac Voltage-Gated Na+ Channels.
Anesthesia and analgesia.
2017 01; 124(1):52-60. doi:
10.1213/ane.0000000000001673. [PMID: 27861438] - Giacomo Rossitto, Diego Miotto, Michele Battistel, Giulio Barbiero, Giuseppe Maiolino, Valeria Bisogni, Viola Sanga, Gian Paolo Rossi. Metoclopramide unmasks potentially misleading contralateral suppression in patients undergoing adrenal vein sampling for primary aldosteronism.
Journal of hypertension.
2016 11; 34(11):2258-65. doi:
10.1097/hjh.0000000000001082. [PMID: 27512976] - Venkateswaran Shekar, Abhi Shah, Mohammad Shadid, Jing-Tao Wu, Jayaprakasam Bolleddula, Swapan Chowdhury. An accelerated background subtraction algorithm for processing high-resolution MS data and its application to metabolite identification.
Bioanalysis.
2016 Aug; 8(16):1693-707. doi:
10.4155/bio-2016-0101. [PMID: 27460980] - Jennyfer Cázares-Delgadillo, Adriana Ganem-Rondero, Virginia Merino, Yogeshvar N Kalia. Controlled transdermal iontophoresis for poly-pharmacotherapy: Simultaneous delivery of granisetron, metoclopramide and dexamethasone sodium phosphate in vitro and in vivo.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2016 Mar; 85(?):31-8. doi:
10.1016/j.ejps.2016.01.027. [PMID: 26826281] - Géraldine Pottier, Solène Marie, Sébastien Goutal, Sylvain Auvity, Marie-Anne Peyronneau, Simon Stute, Raphaël Boisgard, Frédéric Dollé, Irène Buvat, Fabien Caillé, Nicolas Tournier. Imaging the Impact of the P-Glycoprotein (ABCB1) Function on the Brain Kinetics of Metoclopramide.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2016 Feb; 57(2):309-14. doi:
10.2967/jnumed.115.164350. [PMID: 26585058] - André-Michael Beer. [Phytotherapy for control of nausea and vomiting].
MMW Fortschritte der Medizin.
2015 Dec; 157(21-22):26. doi:
10.1007/s15006-015-7592-z. [PMID: 26960848] - Di Wang, Wei Wang, Yulin Zhou, Juan Wang, Dongxu Jia, Hei Kiu Wong, Zhang-Jin Zhang. Studies on the regulatory effect of Peony-Glycyrrhiza Decoction on prolactin hyperactivity and underlying mechanism in hyperprolactinemia rat model.
Neuroscience letters.
2015 Oct; 606(?):60-5. doi:
10.1016/j.neulet.2015.08.024. [PMID: 26297122] - Mario Festin. Nausea and Vomiting in Early Pregnancy.
American family physician.
2015 Sep; 92(6):516-7. doi:
". [PMID: 26371736] - Bei Hu, Heng Ye, Cheng Sun, Yichen Zhang, Zhigang Lao, Fanghong Wu, Zhaohui Liu, Linxi Huang, Changchun Qu, Lewu Xian, Hao Wu, Yingjie Jiao, Junling Liu, Juyu Cai, Weiying Chen, Zhiqiang Nie, Zaiyi Liu, Chunbo Chen. Metoclopramide or domperidone improves post-pyloric placement of spiral nasojejunal tubes in critically ill patients: a prospective, multicenter, open-label, randomized, controlled clinical trial.
Critical care (London, England).
2015 Feb; 19(?):61. doi:
10.1186/s13054-015-0784-1. [PMID: 25880172] - Mariko Takayasu, Kouko Hamamoto, Hiroshi Satoh, Toshihiro Ichijo, Toru Takahashi, Kazuhisa Furuhama. Pharmacokinetics of metoclopramide in calves with renal dysfunction.
The Journal of veterinary medical science.
2015 Feb; 77(2):261-3. doi:
10.1292/jvms.14-0301. [PMID: 25373879] - Sonia Goineau, Philippe Guillaume, Vincent Castagné. Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat.
Fundamental & clinical pharmacology.
2015 Feb; 29(1):86-94. doi:
10.1111/fcp.12086. [PMID: 24920467] - Anouar Jarraya, Sahar Elleuch, Jawhar Zouari, Khaled Trigui, Abidi Sofiene, Mohamed Smaoui, Kamel Kolsi. [Hyperemesis gravidarum with severe electrolyte disorders: report of a case].
The Pan African medical journal.
2015; 20(?):264. doi:
10.11604/pamj.2015.20.264.6298. [PMID: 26161187] - Scott G Blair, Andrew C Bright, Ryan O Kennedy, John M Allen, Mohammad Amin Frotan, Sidney B Brevard, Richard P Gonzalez, Jon D Simmons. Green urine in the intensive care unit: is this clinically relevant?.
The American surgeon.
2015 Jan; 81(1):E32-3. doi:
10.1177/000313481508100122. [PMID: 25569058] - Liliane Spazzapam Lima, Patrícia Los Weinert, Leonardo Pezza, Helena Redigolo Pezza. Sensitive flow-injection spectrophotometric analysis of bromopride.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2014 Dec; 133(?):597-604. doi:
10.1016/j.saa.2014.06.027. [PMID: 24992919] - ". [Gastrointestinal motility disorders. Effective phytotherapy alternatives to MCP (metoclopramide)].
MMW Fortschritte der Medizin.
2014 Nov; 156(19):80-1. doi:
". [PMID: 25510031] - Hussam A S Murad, Hossam M Abdallah. Black tea extract and its thearubigins relieve the sildenafil-induced delayed gut motility in mice: a possible role of nitric oxide.
Phytotherapy research : PTR.
2014 Nov; 28(11):1687-91. doi:
10.1002/ptr.5183. [PMID: 24895242] - D F do Nascimento, A L A e Silva Leite, R A de Moraes, G C Camarão, F A F Bezerra, M O de Moraes, M E A de Moraes. Effect of dimeticone and pepsin on the bioavailability of metoclopramide in healthy volunteers.
Drug research.
2014 Oct; 64(10):537-40. doi:
10.1055/s-0033-1363250. [PMID: 24504688] - Tomasz Urbanowicz, Magdalena Pawłowska, Piotr Buczkowski, Bartłomiej Perek, Hanna Baszyńska-Wachowiak, Ewa Straburzyńska-Migaj, Marek Jemielity. Seizures after heart transplantation--two cases of non-immunosuppressant drug interactions in young patients.
Annals of transplantation.
2014 Aug; 19(?):417-20. doi:
10.12659/aot.890743. [PMID: 25152323] - Danielle Weinman, Olivia Nicastro, Olabiyi Akala, Benjamin W Friedman. Parenteral treatment of episodic tension-type headache: a systematic review.
Headache.
2014 Feb; 54(2):260-8. doi:
10.1111/head.12287. [PMID: 24433525] - Mehmet Tercan, Esra Mercanoglu Efe, Gurkan Turker, Fatma Nur Kaya, Belgin Yavascaoglu, Yesim Ozarda, Elif Basagan Mogol. Do metoclopramide and ondansetrone alter mivacurium-induced neuromuscular blockade? - a randomised trial.
Brazilian journal of anesthesiology (Elsevier).
2014 Jan; 64(1):35-9. doi:
10.1016/j.bjane.2013.04.008. [PMID: 24565386] - Radwa A Mohamed, Haidy A Abass, Mohamed A Attia, Ola A Heikal. Formulation and evaluation of metoclopramide solid lipid nanoparticles for rectal suppository.
The Journal of pharmacy and pharmacology.
2013 Nov; 65(11):1607-21. doi:
10.1111/jphp.12136. [PMID: 24102470] - Johannes Hofland, Leo J Hofland, Peter M van Koetsveld, Jacobie Steenbergen, Wouter W de Herder, Casper H van Eijck, Ronald R de Krijger, Francien H van Nederveen, Maarten O van Aken, Johannes W de Groot, Thera P Links, Frank H de Jong, Richard A Feelders. ACTH-independent macronodular adrenocortical hyperplasia reveals prevalent aberrant in vivo and in vitro responses to hormonal stimuli and coupling of arginine-vasopressin type 1a receptor to 11β-hydroxylase.
Orphanet journal of rare diseases.
2013 Sep; 8(?):142. doi:
10.1186/1750-1172-8-142. [PMID: 24034279] - Z Fazliogullari, A K Karabulut, I I Uysal, N Unver Dogan, H Acar. Investigation of developmental toxicity and teratogenicity of antiemetics on rat embryos cultured in vitro.
Anatomia, histologia, embryologia.
2013 Aug; 42(4):239-46. doi:
10.1111/ahe.12007. [PMID: 23002952] - Z Eras, S S Oğuz, U Dilmen. Is metoclopramide safe for the premature infant?.
European review for medical and pharmacological sciences.
2013 Jun; 17(12):1655-7. doi:
NULL. [PMID: 23832734] - Jian-qin Lv, Rui-zhi Feng, Ning Li. P6 acupoint stimulation for prevention of postoperative nausea and vomiting in patients undergoing craniotomy: study protocol for a randomized controlled trial.
Trials.
2013 May; 14(?):153. doi:
10.1186/1745-6215-14-153. [PMID: 23710881] - Kouko Hamamoto, Yasuharu Mizuno, Masaki Kato, Norio Yamagishi, Kazuhisa Furuhama. Simple and sensitive method for measurement of metoclopramide in cattle plasma by LC-MS/MS using a multimode chromatography.
The Journal of veterinary medical science.
2013 May; 75(4):509-13. doi:
10.1292/jvms.12-0220. [PMID: 23149484] - T K Shaughnessy, K J Larson, J S Polakowski, R L Martin. Pharmacological comparison of peristaltic effects in rats and mice.
Journal of pharmacological and toxicological methods.
2013 May; 67(3):129-33. doi:
10.1016/j.vascn.2013.02.001. [PMID: 23403246] - Marwa A A Ragab. Effect of metoclopramide on the excretion rate of paracetamol using HPLC-DAD.
Journal of chromatographic science.
2013 Apr; 51(4):383-90. doi:
10.1093/chromsci/bms152. [PMID: 23042837] - Pilar Sánchez, Jesús M Torres, Beatriz Castro, José F Frías, Esperanza Ortega. Effects of metoclopramide on mRNA levels of steroid 5α-reductase isozymes in prostate of adult rats.
Journal of physiology and biochemistry.
2013 Mar; 69(1):133-40. doi:
10.1007/s13105-012-0197-4. [PMID: 22806172] - Federico J Capparelli, Mauricio Abello, L Patricio Maskin, Eugenia Arista, Alejandro Hlavnicka, Maria Fernanda Diaz, Daniel Varela, Nestor A Wainsztein. QTc prolongation after brain surgery.
Neurological research.
2013 Mar; 35(2):159-62. doi:
10.1179/1743132813y.0000000169. [PMID: 23452578] - Xiong Wang, Yong-Gang Chen, Li Ma, Zhi-Hui Li, Ju-Yi Li, Xin-Guo Liu, Ji-Li Zou, Jin-Hu Wu. Effect of Chinese medical herbs-Huiru Yizeng Yihao on hyperprolactinemia and hyperplasia of mammary gland in mice.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2013; 10(4):24-35. doi:
10.4314/ajtcam.v10i4.5. [PMID: 24146497] - Christine E Dunne, Jennifer L Bushee, Upendra A Argikar. Metabolism of bromopride in mouse, rat, rabbit, dog, monkey, and human hepatocytes.
Drug metabolism and pharmacokinetics.
2013; 28(6):453-61. doi:
10.2133/dmpk.dmpk-13-rg-010. [PMID: 23615565] - J M Shrestha, R Shrestha, K Khanal. Abortifacient effect of metoclopramide in female albino rats.
Kathmandu University medical journal (KUMJ).
2013 Jan; 11(41):9-13. doi:
. [PMID: 23774405] - Di Wang, Hei Kiu Wong, Li Zhang, Grainne M McAlonan, Xiao-Min Wang, Stephen Cho Wing Sze, Yi-Bin Feng, Zhang-Jin Zhang. Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia.
Progress in neuro-psychopharmacology & biological psychiatry.
2012 Dec; 39(2):332-8. doi:
10.1016/j.pnpbp.2012.07.005. [PMID: 22796279] - Roberto Bernardo-Escudero, Rosalba Alonso-Campero, María Teresa de Jesús Francisco-Doce, Myriam Cortés-Fuentes, Miriam Villa-Vargas, Juan Angeles-Uribe. Comparison of the pharmacokinetics of a new 30 mg modified-release tablet formulation of metoclopramide for once-a-day administration versus 10 mg immediate-release tablets: a single and multiple-dose, randomized, open-label, parallel study in healthy male subjects.
European journal of drug metabolism and pharmacokinetics.
2012 Dec; 37(4):279-88. doi:
10.1007/s13318-012-0082-0. [PMID: 22328192] - Roxanne Dutia, Andrea J Kim, Eugene Mosharov, Eriika Savontaus, Streamson C Chua, Sharon L Wardlaw. Regulation of prolactin in mice with altered hypothalamic melanocortin activity.
Peptides.
2012 Sep; 37(1):6-12. doi:
10.1016/j.peptides.2012.07.006. [PMID: 22800691] - Abdullah Ehsani-Kheradgerdi, Kamran Sharifi, Mehrdad Mohri, Walter Grünberg. Evaluation of a modified acetaminophen absorption test to estimate the abomasal emptying rate in Holstein-Friesian heifers.
American journal of veterinary research.
2011 Dec; 72(12):1600-6. doi:
10.2460/ajvr.72.12.1600. [PMID: 22126687] - Nikhil Kasliwal, Jeetendra Singh Negi, Vandana Jugran, Rahul Jain. Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet.
Archives of pharmacal research.
2011 Oct; 34(10):1691-700. doi:
10.1007/s12272-011-1013-3. [PMID: 22076769] - Teresa M Seccia, Diego Miotto, Renzo De Toni, Valentina Gallina, Matteo Vincenzi, Achille C Pessina, Gian Paolo Rossi. Subtyping of primary aldosteronism by adrenal vein sampling: effect of acute D(2) receptor dopaminergic blockade on adrenal vein cortisol and chromogranin A levels.
European journal of endocrinology.
2011 Jul; 165(1):85-90. doi:
10.1530/eje-11-0246. [PMID: 21490124] - Noel E Radwanski, Rosario Cerundolo, Frances S Shofer, Michael J Hanley, Michael H Court. Effects of powdered whole grapefruit and metoclopramide on the pharmacokinetics of cyclosporine in dogs.
American journal of veterinary research.
2011 May; 72(5):687-93. doi:
10.2460/ajvr.72.5.687. [PMID: 21529222] - Roberto Bernardo-Escudero, Rosalba Alonso-Campero, María Teresa de Jesús Francisco-Doce, Myriam Cortés-Fuentes, Miriam Villa-Vargas, Juan Angeles-Uribe. Comparison of the pharmacokinetics of a new 15-mg modified-release tablet formulation of metoclopramide versus a 10-mg immediate-release tablet: a single- and multiple-dose, randomized, open-label, parallel-group study in healthy Mexican male volunteers.
Clinical therapeutics.
2011 May; 33(5):630-43. doi:
10.1016/j.clinthera.2011.04.016. [PMID: 21665047] - C I Messini, K Dafopoulos, N Chalvatzas, P Georgoulias, G Anifandis, I E Messinis. Effect of ghrelin and metoclopramide on prolactin secretion in normal women.
Journal of endocrinological investigation.
2011 Apr; 34(4):276-9. doi:
10.1007/bf03347085. [PMID: 20530986] - M S Attia, A M Othman, E Elraghi, Hassan Y Aboul-Enein. Spectrofluorimetric assessment of metoclopramide hydrochloride using terbium doped in PMMA matrix optical sensor.
Journal of fluorescence.
2011 Mar; 21(2):739-45. doi:
10.1007/s10895-010-0764-4. [PMID: 21052809] - Sheng Chen, Philip Seeman, Fang Liu. Antipsychotic drug binding in the substantia nigra: an examination of high metoclopramide binding in the brains of normal, Alzheimer's disease, Huntington's disease, and Multiple Sclerosis patients, and its relation to tardive dyskinesia.
Synapse (New York, N.Y.).
2011 Feb; 65(2):119-24. doi:
10.1002/syn.20825. [PMID: 20524177] - Kayode Ogungbenro, Lakshmi Vasist, Robert Maclaren, George Dukes, Malcolm Young, Leon Aarons. A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients.
Pharmaceutical research.
2011 Feb; 28(2):394-404. doi:
10.1007/s11095-010-0290-8. [PMID: 20949310] - Paul Kuo, Max Bellon, Judith Wishart, André J Smout, Richard H Holloway, Robert J L Fraser, Michael Horowitz, Karen L Jones, Christopher K Rayner. Effects of metoclopramide on duodenal motility and flow events, glucose absorption, and incretin hormone release in response to intraduodenal glucose infusion.
American journal of physiology. Gastrointestinal and liver physiology.
2010 Dec; 299(6):G1326-33. doi:
10.1152/ajpgi.00476.2009. [PMID: 20829521] - Neele I Rauers, Frank Stüber, Eun-Hae Lee, Frank Musshoff, Rolf Fimmers, Martin Barann, Ulrike M Stamer. Antagonistic effects of ondansetron and tramadol? A randomized placebo and active drug controlled study.
The journal of pain.
2010 Dec; 11(12):1274-81. doi:
10.1016/j.jpain.2010.03.003. [PMID: 20488759] - Qi YE, Qiao-yan ZHANG, Cheng-jian ZHENG, Yang WANG, Lu-ping QIN. Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro.
Acta pharmacologica Sinica.
2010 Dec; 31(12):1564-8. doi:
10.1038/aps.2010.178. [PMID: 21042288] - Jaswanth Kumar Inamadugu, Rajasekhar Damaramadugu, Ramesh Mullangi, Venkateswarlu Ponneri. Sensitive and selective liquid chromatography-tandem mass spectrometry method for the determination of metoclopramide in human plasma: application to a bioequivalence study.
Biomedical chromatography : BMC.
2010 Sep; 24(9):1006-14. doi:
10.1002/bmc.1401. [PMID: 20352616] - Satoki Inoue, Ryuichi Abe, Masahiko Kawaguchi, Hiroshi Kobayashi, Hitoshi Furuya. Metoclopramide does not prolong duration of action of landiolol attenuating the hemodynamic response to induction of anesthesia and tracheal intubation.
Journal of anesthesia.
2010 Aug; 24(4):649-52. doi:
10.1007/s00540-010-0945-y. [PMID: 20454811] - Upendra A Argikar, Javier Gomez, Din Ung, Henry P Parkman, Swati Nagar. Identification of novel metoclopramide metabolites in humans: in vitro and in vivo studies.
Drug metabolism and disposition: the biological fate of chemicals.
2010 Aug; 38(8):1295-307. doi:
10.1124/dmd.110.033357. [PMID: 20423954] - Bao-Mu Sun, Ming Luo, Sheng-Bing Wu, Xiao-Xia Chen, Meng-Chao Wu. Acupuncture versus metoclopramide in treatment of postoperative gastroparesis syndrome in abdominal surgical patients: a randomized controlled trial.
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2010 Jul; 8(7):641-4. doi:
10.3736/jcim20100707. [PMID: 20619140] - M S Attia, M M Aboaly. Highly sensitive and selective spectrofluorimetric determination of metoclopramide hydrochloride in pharmaceutical tablets and serum samples using Eu3+ ion doped in sol-gel matrix.
Talanta.
2010 Jun; 82(1):78-84. doi:
10.1016/j.talanta.2010.03.062. [PMID: 20685439] - Freddy Contreras, Christian Fouillioux, Mary Lares, Hector Bolívar, Rafael Hernández Hernández, Manuel Velasco, Raquel Cano, Maricarmen Chacin, Valmore Bermúdez. Effects of metoclopramide and metoclopramide/dopamine on blood pressure and insulin release in normotensive, hypertensive, and type 2 diabetic subjects.
American journal of therapeutics.
2010 May; 17(3):320-4. doi:
10.1097/mjt.0b013e3181c1232c. [PMID: 20216207] - Miao Yan, Huan-De Li, Ben-Mei Chen, Xiao-Lei Liu, Yun-Gui Zhu. Determination of metoclopramide in human plasma by LC-ESI-MS and its application to bioequivalance studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Apr; 878(11-12):883-7. doi:
10.1016/j.jchromb.2010.02.006. [PMID: 20189472]