4-Chloro-7-nitrobenzofurazan (BioDeep_00000730644)
代谢物信息卡片
4-Chloro-7-nitrobenzofurazan
化学式: C6H2ClN3O3 (198.9784692)
中文名称: 4-氯-7-硝基-2,1,3-苯并氧杂噁二唑(NBD-Cl)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]
InChI: InChI=1S/C6H2ClN3O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:78878
- PubChem: 25043
- ChEMBL: CHEMBL1743207
- MeSH: 4-Chloro-7-nitrobenzofurazan
- CAS: 10199-89-0
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
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Oxidative medicine and cellular longevity.
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10.1016/j.bbamem.2014.10.001. [PMID: 25312694] - Hua Wang, Wei Zhang, Jun Wan, Weiwei Liu, Bo Yu, Qinghui Jin, Ming Guan. Microchip-based human serum atherogenic lipoprotein profile analysis.
Analytical biochemistry.
2014 Dec; 467(?):75-83. doi:
10.1016/j.ab.2014.08.031. [PMID: 25218022] - Olcay Sagirli, Sıdıka Erturk Toker, Armağan Önal. Development of sensitive spectrofluorimetric and spectrophotometric methods for the determination of duloxetine in capsule and spiked human plasma.
Luminescence : the journal of biological and chemical luminescence.
2014 Dec; 29(8):1014-8. doi:
10.1002/bio.2652. [PMID: 24619645] - Lili Guo, Penghua Fang, Mei Yu, Mingyi Shi, Ping Bo, Zhenwen Zhang. Central alarin ameliorated insulin resistance of adipocytes in type 2 diabetic rats.
The Journal of endocrinology.
2014 Dec; 223(3):217-25. doi:
10.1530/joe-14-0102. [PMID: 25240061] - Nam K Chu, Waheed Shabbir, Erin Bove-Fenderson, Can Araman, Rosa Lemmens-Gruber, David A Harris, Christian F W Becker. A C-terminal membrane anchor affects the interactions of prion proteins with lipid membranes.
The Journal of biological chemistry.
2014 Oct; 289(43):30144-60. doi:
10.1074/jbc.m114.587345. [PMID: 25217642] - Taomin Huang, Xiaoxia Li, Shuang Hu, Bo Zhao, Ping Chen, Xiao Liu, Deyong Ye, Nengneng Cheng. Analysis of fluorescent ceramide and sphingomyelin analogs: a novel approach for in vivo monitoring of sphingomyelin synthase activity.
Lipids.
2014 Oct; 49(10):1071-9. doi:
10.1007/s11745-014-3940-5. [PMID: 25108416] - Xiangying Meng, Xingmei Suo, Wenjun Ding, Xiangjun Li, Yongsheng Ding. Determination of 8-hydroxy-2'- deoxyguanosine derivatized with 4-chloro-7- nitrobenzofurazan in urine by CE-LIF.
Electrophoresis.
2014 Jul; 35(12-13):1873-9. doi:
10.1002/elps.201300650. [PMID: 24634198] - Hirotsune Sasaki, Kaori Toyomura, Wataru Matsuzaki, Aya Okamoto, Naoto Yamaguchi, Hiroyuki Nakamura, Toshihiko Murayama. Regulation of alkaline ceramidase activity by the c-Src-mediated pathway.
Archives of biochemistry and biophysics.
2014 May; 550-551(?):12-9. doi:
10.1016/j.abb.2014.03.012. [PMID: 24708996] - Toshiki Ishikawa, Hiroyuki Imai, Kawai-Yamada Maki. Development of an LC-MS/MS method for the analysis of free sphingoid bases using 4-fluoro-7-nitrobenzofurazan (NBD-F).
Lipids.
2014 Mar; 49(3):295-304. doi:
10.1007/s11745-013-3871-6. [PMID: 24310230] - Tara TeSlaa, Michael A Teitell. Techniques to monitor glycolysis.
Methods in enzymology.
2014; 542(?):91-114. doi:
10.1016/b978-0-12-416618-9.00005-4. [PMID: 24862262] - Meiyan Jiang, Qi Wang, Takatoshi Karasawa, Ja-Won Koo, Hongzhe Li, Peter S Steyger. Sodium-glucose transporter-2 (SGLT2; SLC5A2) enhances cellular uptake of aminoglycosides.
PloS one.
2014; 9(9):e108941. doi:
10.1371/journal.pone.0108941. [PMID: 25268124] - Carlos Wilson, Ariel Contreras-Ferrat, Nataly Venegas, César Osorio-Fuentealba, Mario Pávez, Katherine Montoya, Javier Durán, Rodrigo Maass, Sergio Lavandero, Manuel Estrada. Testosterone increases GLUT4-dependent glucose uptake in cardiomyocytes.
Journal of cellular physiology.
2013 Dec; 228(12):2399-407. doi:
10.1002/jcp.24413. [PMID: 23757167] - João R Robalo, J P Prates Ramalho, Luís M S Loura. NBD-labeled cholesterol analogues in phospholipid bilayers: insights from molecular dynamics.
The journal of physical chemistry. B.
2013 Nov; 117(44):13731-42. doi:
10.1021/jp406135a. [PMID: 24099120] - Lucy J Martínez-Guerrero, Stephen H Wright. Substrate-dependent inhibition of human MATE1 by cationic ionic liquids.
The Journal of pharmacology and experimental therapeutics.
2013 Sep; 346(3):495-503. doi:
10.1124/jpet.113.204206. [PMID: 23785176] - João Mello-Vieira, Tânia Sousa, Ana Coutinho, Aleksander Fedorov, Susana D Lucas, Rui Moreira, Rui E Castro, Cecília M P Rodrigues, Manuel Prieto, Fábio Fernandes. Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.
Biochimica et biophysica acta.
2013 Sep; 1828(9):2152-63. doi:
10.1016/j.bbamem.2013.05.021. [PMID: 23747364] - Xiu-zhen Cao, Ting-yan Mi, Lin Li, Mario A Vermeer, Chen-chen Zhang, Nan Huang, Joshi K Manoj. HPLC-FLD determination of NBD-cholesterol, its ester and other metabolites in cellular lipid extracts.
Biomedical chromatography : BMC.
2013 Jul; 27(7):910-5. doi:
10.1002/bmc.2881. [PMID: 23526237] - Pablo Garrido, Javier Morán, Ana Alonso, Segundo González, Celestino González. 17β-estradiol activates glucose uptake via GLUT4 translocation and PI3K/Akt signaling pathway in MCF-7 cells.
Endocrinology.
2013 Jun; 154(6):1979-89. doi:
10.1210/en.2012-1558. [PMID: 23546602] - Wen-Chang Chang, Szu-Chuan Shen. Effect of water extracts from edible Myrtaceae plants on uptake of 2-(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose in TNF-α-treated FL83B mouse hepatocytes.
Phytotherapy research : PTR.
2013 Feb; 27(2):236-43. doi:
10.1002/ptr.4681. [PMID: 22532499] - Pavel Ostašov, Jan Sýkora, Jana Brejchová, Agnieszka Olżyńska, Martin Hof, Petr Svoboda. FLIM studies of 22- and 25-NBD-cholesterol in living HEK293 cells: plasma membrane change induced by cholesterol depletion.
Chemistry and physics of lipids.
2013 Feb; 167-168(?):62-9. doi:
10.1016/j.chemphyslip.2013.02.006. [PMID: 23466534] - Thamilvaani Manaharan, Cheng Hwee Ming, Uma D Palanisamy. Syzygium aqueum leaf extract and its bioactive compounds enhances pre-adipocyte differentiation and 2-NBDG uptake in 3T3-L1 cells.
Food chemistry.
2013 Jan; 136(2):354-63. doi:
10.1016/j.foodchem.2012.08.056. [PMID: 23122070] - Rob van Zwieten, Andrea E Bochem, Petra M Hilarius, Robin van Bruggen, Ferry Bergkamp, G Kees Hovingh, Arthur J Verhoeven. The cholesterol content of the erythrocyte membrane is an important determinant of phosphatidylserine exposure.
Biochimica et biophysica acta.
2012 Dec; 1821(12):1493-500. doi:
10.1016/j.bbalip.2012.08.008. [PMID: 22960544] - Angel Josabad Alonso-Castro, Rocio Zapata-Bustos, Guadalupe Gómez-Espinoza, Luis A Salazar-Olivo. Isoorientin reverts TNF-α-induced insulin resistance in adipocytes activating the insulin signaling pathway.
Endocrinology.
2012 Nov; 153(11):5222-30. doi:
10.1210/en.2012-1290. [PMID: 22948221] - Natalia S Voynova, Christine Vionnet, Christer S Ejsing, Andreas Conzelmann. A novel pathway of ceramide metabolism in Saccharomyces cerevisiae.
The Biochemical journal.
2012 Oct; 447(1):103-14. doi:
10.1042/bj20120712. [PMID: 22738231] - Abhinav Kanwal, Shailendra Pratap Singh, Paramjit Grover, Sanjay Kumar Banerjee. Development of a cell-based nonradioactive glucose uptake assay system for SGLT1 and SGLT2.
Analytical biochemistry.
2012 Oct; 429(1):70-5. doi:
10.1016/j.ab.2012.07.003. [PMID: 22796500] - Rolffy Ortiz-Andrade, Angel Cabañas-Wuan, Víctor E Arana-Argáez, Angel Josabad Alonso-Castro, Rocio Zapata-Bustos, Luis A Salazar-Olivo, Fabiola Domínguez, Marco Chávez, Candy Carranza-Álvarez, Alejandro García-Carrancá. Antidiabetic effects of Justicia spicigera Schltdl (Acanthaceae).
Journal of ethnopharmacology.
2012 Sep; 143(2):455-62. doi:
10.1016/j.jep.2012.06.043. [PMID: 22819688] - Sevgi Tatar Ulu, Zeynep Aydoğmuş. An HPLC method for the determination of bisoprolol in human plasma and its application to a pharmacokinetic study.
Journal of chromatographic science.
2012 Aug; 50(7):615-9. doi:
10.1093/chromsci/bms056. [PMID: 22553280] - Brad Chazotte. Labeling Golgi with fluorescent ceramides.
Cold Spring Harbor protocols.
2012 Aug; 2012(8):. doi:
10.1101/pdb.prot070599. [PMID: 22854569] - Myung Sunny Kim, Haeng Jeon Hur, Dae Young Kwon, Jin-Taek Hwang. Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice.
Molecular and cellular endocrinology.
2012 Jul; 358(1):127-34. doi:
10.1016/j.mce.2012.03.013. [PMID: 22476082] - Elisa J Cabré, Luís M S Loura, Alexander Fedorov, Jesus Perez-Gil, Manuel Prieto. Topology and lipid selectivity of pulmonary surfactant protein SP-B in membranes: Answers from fluorescence.
Biochimica et biophysica acta.
2012 Jul; 1818(7):1717-25. doi:
10.1016/j.bbamem.2012.03.008. [PMID: 22465066] - Sevgi Tatar Ulu, Muzaffer Tuncel. Determination of bupropion using liquid chromatography with fluorescence detection in pharmaceutical preparations, human plasma and human urine.
Journal of chromatographic science.
2012 May; 50(5):433-9. doi:
10.1093/chromsci/bms020. [PMID: 22454390] - Emmanuelle Reboul, Zeina Soayfane, Aurélie Goncalves, Michela Cantiello, Romain Bott, Michel Nauze, François Tercé, Xavier Collet, Christine Coméra. Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies.
The British journal of nutrition.
2012 May; 107(9):1296-304. doi:
10.1017/s0007114511004405. [PMID: 21929836] - Yanting Song, Takashi Funatsu, Makoto Tsunoda. Rapid determination of amino acids in biological samples using a monolithic silica column.
Amino acids.
2012 May; 42(5):1897-902. doi:
10.1007/s00726-011-0914-2. [PMID: 21505823] - Vera Bandmann, Ulrike Homann. Clathrin-independent endocytosis contributes to uptake of glucose into BY-2 protoplasts.
The Plant journal : for cell and molecular biology.
2012 May; 70(4):578-84. doi:
10.1111/j.1365-313x.2011.04892.x. [PMID: 22211449] - Yoko Nishimura, Satoshi Tadokoro, Masahiko Tanaka, Naohide Hirashima. Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer.
Biochemical and biophysical research communications.
2012 Apr; 420(4):926-30. doi:
10.1016/j.bbrc.2012.03.106. [PMID: 22475486] - Sevgi Tatar Ulu, Muzaffer Tuncel. A sensitive and rapid determination of ranitidine in human plasma by HPLC with fluorescence detection and its application for a pharmacokinetic study.
Journal of chromatographic science.
2012 Apr; 50(4):301-6. doi:
10.1093/chromsci/bms003. [PMID: 22345389] - Miao Chen, Zhigang Tai, Xujia Hu, Mousheng Liu, Yaling Yang. Utility of 4-chloro-7-nitrobenzofurazan for the spectrofluorimetric determination of butylated hydroxyanisole and propyl gallate in foodstuffs.
Journal of food science.
2012 Apr; 77(4):C401-7. doi:
10.1111/j.1750-3841.2011.02607.x. [PMID: 22394117]