Phentermine Hydrochloride (BioDeep_00000728969)
代谢物信息卡片
Phentermine Hydrochloride
化学式: C10H16ClN (185.09712059999998)
中文名称: 盐酸苯丁胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(CC1=CC=CC=C1)N.Cl
InChI: 1H
描述信息
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents
D019440 - Anti-Obesity Agents > D001067 - Appetite Depressants
C78272 - Agent Affecting Nervous System > C29728 - Anorexiant
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:50506
- KEGGdrug: D05459
- PubChem: 70969
- ChEMBL: CHEMBL1200912
- MeSH: Phentermine
- CAS: 1197-21-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Qingyang Shi, Yang Wang, Qiukui Hao, Per Olav Vandvik, Gordon Guyatt, Jing Li, Zhe Chen, Shishi Xu, Yanjiao Shen, Long Ge, Feng Sun, Ling Li, Jiajie Yu, Kailei Nong, Xinyu Zou, Siyi Zhu, Cong Wang, Shengzhao Zhang, Zhi Qiao, Zhongyu Jian, Ya Li, Xinyi Zhang, Kerun Chen, Furong Qu, Yuan Wu, Yazhou He, Haoming Tian, Sheyu Li. Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials.
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Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie.
1982; 126(1-2):185-95. doi:
NULL. [PMID: 7090596] - J R Arch. The contribution of increased thermogenesis to the effect of anorectic drugs on body composition in mice.
The American journal of clinical nutrition.
1981 Dec; 34(12):2763-9. doi:
10.1093/ajcn/34.12.2763. [PMID: 7315777] - R F Minchin, K F Ilett, B W Madsen. Effect of desmethylimipramine on tissue distribution and anorectic activity of chlorphentermine in rats.
Life sciences.
1981 Apr; 28(17):1931-8. doi:
10.1016/0024-3205(81)90301-5. [PMID: 7253800] - S C Woodward. Induction and reversal of pulmonary lipid histiocytosis in rats following oral administration of anorectics cloforex and chlorphentermine.
Journal of toxicology and environmental health.
1981 Mar; 7(3-4):569-83. doi:
10.1080/15287398109530002. [PMID: 7197305] - H Lüllmann, R Lüllmann-Rauch, E U Mösinger. Impairment of renal function in rats with generalized lipidosis as induced by chlorphentermine.
Arzneimittel-Forschung.
1981; 31(5):795-9. doi:
NULL. [PMID: 7196738] - J Sonka, Z Límanová, A Zbirková, O Kratochvíl. Effects of diet, exercise and anorexigenic drugs on serum thyroid hormones.
Endokrinologie.
1980 Dec; 76(3):351-6. doi:
NULL. [PMID: 7472292] - M J Reasor, R A Koshut. Augmentation in antioxidant defense mechanisms in rat alveolar macrophages following induction of phospholipidosis with chlorphentermine.
Toxicology and applied pharmacology.
1980 Sep; 55(2):334-41. doi:
10.1016/0041-008x(80)90095-2. [PMID: 7423522] - M J Reasor, R A Koshut, M J McNulty, M A Trush. Chemiluminescence from rat alveolar macrophages following induction of phospholipidosis with chlorphentermine.
Toxicology and applied pharmacology.
1980 Mar; 52(3):497-506. doi:
10.1016/0041-008x(80)90344-0. [PMID: 7368220] - H Schmalbruch. The early changes in experimental myopathy induced by chloroquine and chlorphentermine.
Journal of neuropathology and experimental neurology.
1980 Jan; 39(1):65-81. doi:
10.1097/00005072-198001000-00006. [PMID: 7359173] - S Kacew, G A Calderwood. Newborn liver and kidney metabolism as influenced by oxygen toxicity and anorectic drugs.
Journal of toxicology and environmental health.
1980 Jan; 6(1):141-54. doi:
10.1080/15287398009529837. [PMID: 6155472] - H D Dell, M Donike, H Jacobi, R Kamp. [In vitro stability and biotransformation of 3'-hydroxy-2-[N-methyl-N-(1,1-dimethyl-2-phenethyl)amino] acetophenone (TVX 960) (author's transl)].
Arzneimittel-Forschung.
1980; 30(7):1138-44. doi:
NULL. [PMID: 7191296] - M J Reasor. Cumene hydroperoxide-mediated lipid peroxidation in rat alveolar macrophages following induction of phospholipidosis with chlorphentermine.
Toxicology.
1980; 18(2):159-68. doi:
10.1016/0300-483x(80)90078-5. [PMID: 7256780] - H Lüllmann, E U Mösinger. Increased lysosomal enzyme activities in tissues of rats suffering from chlorphentermine induced lipidosis.
Biochemical pharmacology.
1979 Apr; 28(7):1015-6. doi:
10.1016/0006-2952(79)90296-x. [PMID: 109091] - R Gräbner, W Meerbach. Morphological and biochemical alterations of the lung after application of chlorphentermine.
Experimentelle Pathologie.
1979; 17(6):303-11. doi:
10.1016/s0014-4908(79)80045-9. [PMID: 527695] - Y Mårde, R Ryhage. Negative-ion mass spectrometry of amphetamine congeners.
Clinical chemistry.
1978 Oct; 24(10):1720-3. doi:
10.1093/clinchem/24.10.1720. [PMID: 699276] - H Schmalbruch. Early changes in chlorphentermine myopathy of rat studied by freeze fracturing.
Muscle & nerve.
1978 Sep; 1(5):421-2. doi:
10.1002/mus.880010516. [PMID: 263983] - D Drenckhahn. Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine.
Virchows Archiv. B, Cell pathology.
1978 May; 27(3):255-66. doi:
10.1007/bf02889000. [PMID: 208230] - S Kacew, T C Dubas, A J Stevenson. Renal and hepatic nucleic acid metabolism in neonates: relation to experimental duration, chlorphentermine dose as well as subsequent withdrawal.
Toxicology.
1978 May; 10(1):77-90. doi:
10.1016/0300-483x(78)90057-4. [PMID: 566970] - A H Beckett, P M Belanger. The disposition of phentermine and its N-oxidized metabolic products in the rabbit.
Xenobiotica; the fate of foreign compounds in biological systems.
1978 Jan; 8(1):55-60. doi:
10.3109/00498257809060383. [PMID: 24306] - S Kacew, R Narbaitz, A J Stevenson. The effects of chlorphentermine and phentermine on certain metabolic parameters associated with development of rat kidney and liver.
Chemico-biological interactions.
1977 Oct; 19(1):61-76. doi:
10.1016/0009-2797(77)90042-4. [PMID: 200375] - D Drenckhahn, R Lüllmann-Rauch. Lens opacities associated with lipidosis-like ultrastructural alterations in rats treated with chloroquine, chlorphentermine, or iprindole.
Experimental eye research.
1977 Jun; 24(6):621-32. doi:
10.1016/0014-4835(77)90120-8. [PMID: 872905] - A H Beckett, P M Bélanger. The metabolism, distribution and elimination of chlorphentermine in man.
British journal of clinical pharmacology.
1977 Apr; 4(2):193-200. doi:
10.1111/j.1365-2125.1977.tb00693.x. [PMID: 16634] - M Michel-Lipowsky, J Caldwell, R L Smith. The reversibility of the N-oxidation of chlorphentermine in vivo [proceedings].
Biochemical Society transactions.
1977; 5(4):1005-6. doi:
10.1042/bst0051005. [PMID: 913762]