Toxiferine (BioDeep_00000007257)
代谢物信息卡片
Toxiferine I
化学式: C40H46N4O2+2 (614.3620576)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[N+]12CCC34C1CC(C(=CCO)C2)C5=CN6C7C(=CN(C53)C8=CC=CC=C48)C9CC1C7(CC[N+]1(CC9=CCO)C)C1=CC=CC=C16
InChI: InChI=1S/C40H46N4O2/c1-43-15-13-39-31-7-3-5-9-33(31)41-22-30-28-20-36-40(14-16-44(36,2)24-26(28)12-18-46)32-8-4-6-10-34(32)42(38(30)40)21-29(37(39)41)27(19-35(39)43)25(23-43)11-17-45/h3-12,21-22,27-28,35-38,45-46H,13-20,23-24H2,1-2H3/q+2/b25-11-,26-12-,29-21-,30-22-/t27-,28-,35-,36-,37-,38-,39+,40+,43-,44-/m0/s1
描述信息
D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists
同义名列表
2 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:9644
- KEGG: C09246
- PubChem: 5281411
- PubChem: 5089093
- ChEMBL: CHEMBL1184078
- MeSH: Toxiferine
- KNApSAcK: C00001776
- CAS: 302-30-7
- PMhub: MS000020566
- PubChem: 11437
- CAS: 6888-23-9
- 3DMET: B05342
- NIKKAJI: J1.422.782B
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Alembert T Tchinda, Olivia Jansen, Jean-Noel Nyemb, Monique Tits, Georges Dive, Luc Angenot, Michel Frédérich. Strychnobaillonine, an unsymmetrical bisindole alkaloid with an unprecedented skeleton from Strychnos icaja roots.
Journal of natural products.
2014 Apr; 77(4):1078-82. doi:
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Masui. The Japanese journal of anesthesiology.
1988 Aug; 37(8):938-42. doi:
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Anaesthesia.
1988 Apr; 43(4):310-1. doi:
10.1111/j.1365-2044.1988.tb08982.x. [PMID: 3377154] - J S Walker, C A Shanks, C Borton, K F Brown. Alcuronium pharmacodynamics in dogs: effect-concentration relationships in the diaphragmatic and limb muscles.
The Journal of pharmacy and pharmacology.
1987 Aug; 39(8):614-20. doi:
10.1111/j.2042-7158.1987.tb03439.x. [PMID: 2888852] - A S Lamont, M S Roberts, L J McLeod. Hypocarbia and muscle relaxant plasma levels.
Anaesthesia and intensive care.
1987 Aug; 15(3):354-5. doi:
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Anaesthesia.
1987 May; 42(5):522-5. doi:
10.1111/j.1365-2044.1987.tb04045.x. [PMID: 3592179] - S Oshita, H Tamura, T Masuda, S Fukuda, H Takeshita. Alcuronium pretreatment attenuates succinylcholine-induced increases in plasma catecholamine concentrations in humans.
Anesthesia and analgesia.
1987 Apr; 66(4):314-6. doi:
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Anaesthesia and intensive care.
1985 May; 13(2):196-8. doi:
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British journal of anaesthesia.
1984 Nov; 56(11):1229-33. doi:
10.1093/bja/56.11.1229. [PMID: 6386020] - I D Stephens, P C Ho, A M Holloway, D W Bourne, E J Triggs. Pharmacokinetics of alcuronium in elderly patients undergoing total hip replacement or aortic reconstructive surgery.
British journal of anaesthesia.
1984 May; 56(5):465-71. doi:
10.1093/bja/56.5.465. [PMID: 6721957] - M F Cummings, W J Russell, D B Frewin, W A Miller. The effects of gallamine and a mixture of pancuronium and alcuronium on the pressor and plasma catecholamine responses to tracheal intubation.
Anaesthesia and intensive care.
1984 Feb; 12(1):22-6. doi:
10.1177/0310057x8401200105. [PMID: 6703312] - O Erkola, A Salmenperä, R Kuoppamäki. Five non-depolarizing muscle relaxants in precurarization.
Acta anaesthesiologica Scandinavica.
1983 Dec; 27(6):427-32. doi:
10.1111/j.1399-6576.1983.tb01981.x. [PMID: 6141695] - B A Baldo, M M Fisher. Anaphylaxis to muscle relaxant drugs: cross-reactivity and molecular basis of binding of IgE antibodies detected by radioimmunoassay.
Molecular immunology.
1983 Dec; 20(12):1393-400. doi:
10.1016/0161-5890(83)90171-2. [PMID: 6656781] - C Tovey, D W Bourne, J Schneider, I D Stephens, E J Triggs. Determination of alcuronium dichloride in plasma by high-performance liquid chromatography without solvent extraction.
Journal of chromatography.
1983 Nov; 278(1):216-9. doi:
10.1016/s0378-4347(00)84778-7. [PMID: 6662884] - B A Baldo, M M Fisher. Detection of serum IgE antibodies that react with alcuronium and tubocurarine after life-threatening reactions to muscle-relaxant drugs.
Anaesthesia and intensive care.
1983 Aug; 11(3):194-7. doi:
10.1177/0310057x8301100302. [PMID: 6614428] - M F Cummings, W J Russell, D B Frewin. Effects of pancuronium and alcuronium on the changes in arterial pressure and plasma catecholamine concentrations during tracheal intubation.
British journal of anaesthesia.
1983 Jul; 55(7):619-23. doi:
10.1093/bja/55.7.619. [PMID: 6871054] - J S Walker, C Shanks, K F Brown. Alcuronium kinetics and plasma concentration-effect relationship.
Clinical pharmacology and therapeutics.
1983 Apr; 33(4):510-6. doi:
10.1038/clpt.1983.69. [PMID: 6831830] - J S Walker, K F Brown, C A Shanks. Alcuronium kinetics in patients undergoing cardiopulmonary bypass surgery.
British journal of clinical pharmacology.
1983 Feb; 15(2):237-44. doi:
10.1111/j.1365-2125.1983.tb01492.x. [PMID: 6601958] - L Brandt, U Henneberg. [Does precurarization prevent the increase of serum potassium after administration of succinylcholine in risk patients? - a case report- (author's transl)].
Anasthesie, Intensivtherapie, Notfallmedizin.
1981 Dec; 16(6):353-5. doi:
NULL. [PMID: 7325351] - J E Parkin. Determination of alcuronium chloride in biological fluids by high-performance liquid chromatography.
Journal of chromatography.
1981 Sep; 225(1):240-4. doi:
10.1016/s0378-4347(00)80268-6. [PMID: 7298752] - P C Ho, I D Stephens, E J Triggs. Caesarean section and placental transfer of alcuronium.
Anaesthesia and intensive care.
1981 May; 9(2):113-8. doi:
10.1177/0310057x8100900202. [PMID: 7258607] - J Walker, C A Shanks, E J Triggs. Clinical pharmacokinetics of alcuronium chloride in man.
European journal of clinical pharmacology.
1980 Jun; 17(6):449-57. doi:
10.1007/bf00570163. [PMID: 7398736] - D Cozanitis, E Haapanen. Studies on muscle relaxants during haemodialysis.
Acta anaesthesiologica Scandinavica.
1979 Jun; 23(3):225-34. doi:
10.1111/j.1399-6576.1979.tb01444.x. [PMID: 484179] - C Le Guilcher, H Roumane, J P Campion, C Mai Van Dau, B Launois. [Anesthesia in renal transplantation. Place of neuroleptoanalgesia and curarizing agents in renal transplantation].
Anesthesie, analgesie, reanimation.
1978 Jan; 35(1):119-28. doi:
NULL. [PMID: 354430] - M L Yeung. Plasma proteins, packed-cell volume and requirements for alcuronium.
British journal of anaesthesia.
1976 Sep; 48(9):859-63. doi:
10.1093/bja/48.9.859. [PMID: 971391] - A Matsuki, S P Kothary, E K Zsigmond. Effect of gallamine on plasma cortisol and catecholamine levels in man.
Canadian Anaesthetists' Society journal.
1973 Jul; 20(4):539-45. doi:
10.1007/bf03026215. [PMID: 4718358] - K B Vetten. Immunosuppressive therapy and anaesthesia.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
1973 May; 47(18):767-70. doi:
NULL. [PMID: 4267975] - D Nizard, G Debras, G Vigreux, M Poisvert. [Diallyl-nor-toxiferine as a curarizing agent in renal failure patients].
Cahiers d'anesthesiologie.
1972 Nov; 20(7):775-83. doi:
NULL. [PMID: 4660729] - P G Waser, J Reller. Distribution and pharmacokinetics of 14 C-toxiferine in rats.
Agents and actions.
1972 Jun; 2(4):170-5. doi:
10.1007/bf01965855. [PMID: 5041048] - J Stovner, L Theodorsen, E Bjelke. Sensitivity to dimethyltubocurarine and toxiferine with special reference to serum proteins.
British journal of anaesthesia.
1972 Apr; 44(4):374-80. doi:
10.1093/bja/44.4.374. [PMID: 5032074] - J Raaflaub, P Frey. [Pharmacokinetics of diallyl-nor-toxiferine in man].
Arzneimittel-Forschung.
1972 Jan; 22(1):73-8. doi:
NULL. [PMID: 5067002] - D Kettler, U Braun, L A Cott, H W Heiss, I Hensel, J Martel, K Paschen, H J Bretschneider. [Combination of piritramide and N 2 O--a new anesthetic procedure. I. Animal experiment studies].
Zeitschrift fur praktische Anasthesie und Wiederbelebung.
1971 Oct; 6(5):330-8. doi:
NULL. [PMID: 4257163] - J Stovner, L Theodorsen, E Bjelke. Sensitivity to tubocurarine and alcuronium with special reference to plasma protein pattern.
British journal of anaesthesia.
1971 Apr; 43(4):385-91. doi:
10.1093/bja/43.4.385. [PMID: 4102503] - J Stovner, L Theodorsen, E Bjelke. Sensitivity to tubocurarine and alcuronium with special reference to plasma protein pattern.
Anaesthesia.
1971 Jan; 26(1):92. doi:
10.1111/j.1365-2044.1971.tb04732.x. [PMID: 5540034] - R Höfer, J Krenn, G Pfeiffer, K Steinbereithner. [Excretion of diallyl-nor-toxiferine in kidney transplantation].
Der Anaesthesist.
1969 Sep; 18(9):304-8. doi:
NULL. [PMID: 4909221] - R Gattiker. [Anesthesia problems in clinical kidney transplantation].
Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie.
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NULL. [PMID: 4873619] - P G Waser. [Biological aspects of drug effects].
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1966 Mar; 41(3):129-41. doi:
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