Nitrosoguanidine (BioDeep_00000721412)
代谢物信息卡片
1-Nitrosoguanidine
化学式: CH4N4O (88.03850940000001)
中文名称: 亚硝基胍
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=NN=O)(N)N
InChI: InChI=1S/CH4N4O/c2-1(3)4-5-6/h(H4,2,3,4,6)
描述信息
D009676 - Noxae > D009153 - Mutagens > D009604 - Nitrosoguanidines
同义名列表
2 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yong He, Hong-Hong Liu, Xue-Lin Zhou, Ting-Ting He, Ao-Zhe Zhang, Xin Wang, Shi-Zhang Wei, Hao-Tian Li, Li-Sheng Chen, Lei Chang, Yan-Ling Zhao, Man-Yi Jing. Rutaecarpine Ameliorates Murine N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Chronic Atrophic Gastritis by Sonic Hedgehog Pathway.
Molecules (Basel, Switzerland).
2023 Aug; 28(17):. doi:
10.3390/molecules28176294. [PMID: 37687125] - Zirong Zhu, Wenhui Chen, Hongbo Zhou, Haina Cheng, Sisi Luo, Kexuan Zhou, Pengji Zhou, Liqiu Xia, Xuezhi Ding. ARTP and NTG compound mutations improved Cry protein production and virulence of Bacillus thuringiensis X023.
Applied microbiology and biotechnology.
2022 Jun; 106(11):4211-4221. doi:
10.1007/s00253-022-11983-2. [PMID: 35622123] - R A Agabeĭli, G G Mirzazade. [Genoprotective activities of the oils from leaves and fruits of Fagus orientalis Lipsky].
TSitologiia i genetika.
2011 Jul; 45(4):23-8. doi:
". [PMID: 21950139] - B Sandesh Kamath, R Vidhyavathi, R Sarada, G A Ravishankar. Enhancement of carotenoids by mutation and stress induced carotenogenic genes in Haematococcus pluvialis mutants.
Bioresource technology.
2008 Dec; 99(18):8667-73. doi:
10.1016/j.biortech.2008.04.013. [PMID: 18499448] - Zhiqiang Pan, Ameeta K Agarwal, Tao Xu, Qin Feng, Scott R Baerson, Stephen O Duke, Agnes M Rimando. Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol.
BMC medical genomics.
2008 Mar; 1(?):7. doi:
10.1186/1755-8794-1-7. [PMID: 18366703] - Kevin A Ford, John E Casida. Unique and common metabolites of thiamethoxam, clothianidin, and dinotefuran in mice.
Chemical research in toxicology.
2006 Nov; 19(11):1549-56. doi:
10.1021/tx0601859. [PMID: 17112244] - Sanjay A Desai, Abdulnaser Alkhalil, Myungsa Kang, Umar Ashfaq, My-Le Nguyen. Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum.
The Journal of biological chemistry.
2005 Apr; 280(17):16861-7. doi:
10.1074/jbc.m414629200. [PMID: 15701633] - M B Guseĭnov, R A Agabeĭli, U K Alekperov. [Modification of mutation processes in culture of human lymphocytes with tea extracts].
TSitologiia i genetika.
2005 Mar; 39(2):55-8. doi:
". [PMID: 16161414] - Eman M El-Masry, Mohamed B Abou-Donia. Reversal of P-glycoprotein expressed in Escherichia coli leaky mutant by ascorbic acid.
Life sciences.
2003 Jul; 73(8):981-91. doi:
10.1016/s0024-3205(03)00376-x. [PMID: 12818351] - V V Lobanov, I S Shestialtynoba, V V Agafonova, V V Sukhar', B L Mazrukho, N A Aronova. [Antigenic specificity of Vibrio cholerae O139 nitrosoguanidine mutants].
Zhurnal mikrobiologii, epidemiologii i immunobiologii.
2003 May; ?(3):81-2. doi:
NULL. [PMID: 12886640] - David M Byers, Zhiwei Shen. Biochemical evidence against protein-mediated uptake of myristic acid in the bioluminescent marine bacterium Vibrio harveyi.
Canadian journal of microbiology.
2002 Oct; 48(10):933-9. doi:
10.1139/w02-092. [PMID: 12489783] - Basil N Ziogas, Anastasios N Markoglou, Aliki Tzima. A non-Mendelian inheritance of resistance to strobilurin fungicides in Ustilago maydis.
Pest management science.
2002 Sep; 58(9):908-16. doi:
10.1002/ps.543. [PMID: 12233180] - S Reiser, C Somerville. Isolation of mutants of Acinetobacter calcoaceticus deficient in wax ester synthesis and complementation of one mutation with a gene encoding a fatty acyl coenzyme A reductase.
Journal of bacteriology.
1997 May; 179(9):2969-75. doi:
10.1128/jb.179.9.2969-2975.1997. [PMID: 9139916] - M Chidambaram, B Sharma, S F Petras, C P Reese, S Froshauer, G M Weinstock. Isolation of Pasteurella haemolytica leukotoxin mutants.
Infection and immunity.
1995 Mar; 63(3):1027-32. doi:
10.1128/iai.63.3.1027-1032.1995. [PMID: 7868223] - A Delgado, J L Ramos. Genetic evidence for activation of the positive transcriptional regulator Xy1R, a member of the NtrC family of regulators, by effector binding.
The Journal of biological chemistry.
1994 Mar; 269(11):8059-62. doi:
. [PMID: 8132529] - G J Pazour, C N Ta, A Das. Mutants of Agrobacterium tumefaciens with elevated vir gene expression.
Proceedings of the National Academy of Sciences of the United States of America.
1991 Aug; 88(16):6941-5. doi:
10.1073/pnas.88.16.6941. [PMID: 1908084] - V U Ahmad, V Sultana. Spermine alkaloids from Schweinfurthia papilionacea.
Journal of natural products.
1990 Sep; 53(5):1162-7. doi:
10.1021/np50071a004. [PMID: 2292684] - D E Jensen, R L Mackay. Rat, mouse and hamster isozyme specificity in the glutathione transferase-mediated denitrosation of nitrosoguanidinium compounds.
Cancer research.
1990 Mar; 50(5):1440-8. doi:
NULL. [PMID: 2302709] - D H Fine, E U Goff, R A Johnson, D P Rounbehler. Thermal energy analysis of N-nitroso compounds, including ureas, urethanes and guanidines.
IARC scientific publications.
1987; ?(84):216-8. doi:
NULL. [PMID: 3679371] - I I Danilenko. [Mutagenic action of nitrosomethylguanidine on synchronously growing Candida tropicalis D-2 cells with various amounts of intracellular lipids].
Genetika.
1982 May; 18(5):848-50. doi:
". [PMID: 7201435] - T Nishimoto, C Basilico. Analysis of a method for selecting temperature-sensitive mutants of BHK cells.
Somatic cell genetics.
1978 May; 4(3):323-40. doi:
10.1007/bf01542846. [PMID: 694723] - Y Morishita. Effect of N-methyl-N'-nitro-N-nitrosoguanidine on the fecal flora of rats.
Japanese journal of microbiology.
1976 Jun; 20(3):247-8. doi:
10.1111/j.1348-0421.1976.tb00983.x. [PMID: 787606] - S S Hussain, H Chander, B Ranganathan. Activation of lipolytic activity of Streptococcus faecalis by nitrosoguanidine.
Folia microbiologica.
1976; 21(1):73-4. doi:
10.1007/bf02879010. [PMID: 814069] - Y Tabuchi, T Mitsuno, T Sugiyama. Mucosal damage induced by various gastric carcinogens in the glandular stomach of the rat.
Journal of the National Cancer Institute.
1975 Dec; 55(6):1395-401. doi:
10.1093/jnci/55.6.1395. [PMID: 1206759] - M Floyd, G Bone, I Lauder, W Lowe. A nephropathy occuring in rats treated with dinitrochlorobenzene and N-methyl-N-nitroso guanidine.
Beitrage zur Pathologie.
1975 Aug; 155(4):343-56. doi:
10.1016/s0005-8165(75)80100-4. [PMID: 1180808] - J E Cleaver, S Weil. UV-induced reversion of a temperature-sensitive late mutant of simian virus 40 to a wild-type phenotype.
Journal of virology.
1975 Jul; 16(1):214-6. doi:
10.1128/jvi.16.1.214-216.1975. [PMID: 166205] - K Oguma, H Iida, K Inoue. Observations on nonconverting phage, c-n71, obtained from a nontoxigenic strain of Clostridium botulinum type C.
Japanese journal of microbiology.
1975 Jun; 19(3):167-72. doi:
10.1111/j.1348-0421.1975.tb00864.x. [PMID: 1100888] - G Steele, H O Sjögren, J E Rosengren, C Lindström, A Larsson, L Leandoer. Sequential studies of serum blocking activity in rats bearing chemically induced primary bowel tumors.
Journal of the National Cancer Institute.
1975 Apr; 54(4):959-67. doi:
NULL. [PMID: 1127725] - R W Koment, F Rapp. Temperature-sensitive host range mutants of herpes simplex virus type 2.
Journal of virology.
1975 Apr; 15(4):812-9. doi:
10.1128/jvi.15.4.812-819.1975. [PMID: 163920] - L E Sanchez, J V Leary, R M Endo. Chemical mutagenesis of Fusarium oxysporum f. sp. lycopersici: non-selected changes in pathogenicity of auxotrophic mutants.
Journal of general microbiology.
1975 Apr; 87(2):326-32. doi:
10.1099/00221287-87-2-326. [PMID: 167104] - J R Kinghorn, J A Pateman. The structural gene for NADP L-glutamate dehydrogenase in Aspergillus nidulans.
Journal of general microbiology.
1975 Feb; 86(2):294-300. doi:
10.1099/00221287-86-2-294. [PMID: 234511] - E E Henderson, A J Norin, B S Strauss. Induction of permanently proliferating human lymphoblastoid lines by N-methyl-N'-nitro-N-nitrosoguanidine.
Cancer research.
1975 Feb; 35(2):358-63. doi:
NULL. [PMID: 162872] - P Sherlock, M Lipkin, S J Winawer. Predisposing factors in carcinoma of the colon.
Advances in internal medicine.
1975; 20(?):121-50. doi:
NULL. [PMID: 1090115] - N K Mishra, G Di Mayorca. In vitro malignant transformation of cells by chemical carcinogens.
Biochimica et biophysica acta.
1974 Dec; 355(3-4):205-19. doi:
10.1016/0304-419x(74)90010-9. [PMID: 4617599] - K Ohyama. Properties of 5-bromodeoxyuridine-resistant lines of higher plant cells in liquid culture.
Experimental cell research.
1974 Nov; 89(1):31-8. doi:
10.1016/0014-4827(74)90183-9. [PMID: 4279827] - D Wild. Serum effect on the yield of chemically induced 8-azaguanine-resistant mutants in Chinese hamster cell cultures.
Mutation research.
1974 Nov; 25(2):229-34. doi:
10.1016/0027-5107(74)90022-0. [PMID: 4431422] - D Kamely, J W Littlefield. Isolation and characterization of norleucine-resistant baby hamster kidney cells.
Experimental cell research.
1974 Nov; 89(1):154-60. doi:
10.1016/0014-4827(74)90198-0. [PMID: 4373259] - G Steele, H O Sjogren. Embryonic antigens associated with chemically induced colon carcinomas in rats.
International journal of cancer.
1974 Oct; 14(4):435-44. doi:
10.1002/ijc.2910140403. [PMID: 4376522] - E L Wynder, B S Reddy. The epidemiology of cancer of the large bowel.
The American journal of digestive diseases.
1974 Oct; 19(10):937-46. doi:
10.1007/bf01076220. [PMID: 4608024] - K Shiroki, H Shimojo. Analysis of adenovirus 12 temperature-sensitive mutants defective in viral DNA replication.
Virology.
1974 Oct; 61(2):474-85. doi:
10.1016/0042-6822(74)90283-9. [PMID: 4609393] - P Tegtmeyer, J A Robb, C Widmer, H L Ozer. Altered protein metabolism in infection by the late tsB11 mutant of simian virus 40.
Journal of virology.
1974 Oct; 14(4):997-1007. doi:
10.1128/jvi.14.4.997-1007.1974. [PMID: 4371515] - E H Harris, J E Boynton, N W Gillham. Chloroplast ribosome biogenesis in Chlamydomonas. Selection and characterization of mutants blocked in ribosome formation.
The Journal of cell biology.
1974 Oct; 63(1):160-79. doi:
10.1083/jcb.63.1.160. [PMID: 4423964] - W F Doolittle, R A Singer. Mutational analysis of dark endogenous metabolism in the blue-green bacterium Anacystis nidulans.
Journal of bacteriology.
1974 Sep; 119(3):677-83. doi:
10.1128/jb.119.3.677-683.1974. [PMID: 4212183] - N Ledinko. Temperature-sensitive mutants of adenovirus type 12 defective in viral DNA synthesis.
Journal of virology.
1974 Sep; 14(3):457-68. doi:
10.1128/jvi.14.3.457-468.1974. [PMID: 4854616] - K Yamaguchi, Y Nagata, B Maruo. Genetic control of the rate of alpha-amylase synthesis in Bacillus subtilis.
Journal of bacteriology.
1974 Aug; 119(2):410-5. doi:
10.1128/jb.119.2.410-415.1974. [PMID: 4212030] - K Yamaguchi, Y Nagata, B Maruo. Isolation of mutants defective in alpha-amylase from Bacillus subtilis: genetic analyses.
Journal of bacteriology.
1974 Aug; 119(2):416-24. doi:
10.1128/jb.119.2.416-424.1974. [PMID: 4212116] - G Steele, H O Sjögren. Cross-reacting tumor-associated antigen (s) among chemically induced rat colon carcinomas.
Cancer research.
1974 Aug; 34(8):1801-7. doi:
NULL. [PMID: 4366501] - G Steele, J Ankerst, H O Sjögren. Alteration of in vitro anti-tumor activity of tumor-bearer sera by absorption with Staphylococcus aureus, Cowan I.
International journal of cancer.
1974 Jul; 14(1):83-92. doi:
10.1002/ijc.2910140110. [PMID: 4376510] - D L Coplin, L Sequeira, R S Hanson. Pseudomonas solanacearum: virulence of biochemical mutants.
Canadian journal of microbiology.
1974 Apr; 20(4):519-29. doi:
10.1139/m74-080. [PMID: 4828867] - E G Gollub, P Trocha, P K Liu, D B Sprinson. Yeast mutants requiring ergosterol as only lipid supplement.
Biochemical and biophysical research communications.
1974 Jan; 56(2):471-7. doi:
10.1016/0006-291x(74)90866-3. [PMID: 4363054] - C Basilico, H K Meiss. Methods for selecting and studying temperature-sensitive mutants of BHK-21 cells.
Methods in cell biology.
1974; 8(0):1-22. doi:
10.1016/s0091-679x(08)60440-9. [PMID: 4366305] - B Singer, C Condit. Protein synthesis in virus-infected plants. 3. Effects of tobacco mosaic virus mutants on protein synthesis in Nicotiana tabacum.
Virology.
1974 Jan; 57(1):42-8. doi:
10.1016/0042-6822(74)90106-8. [PMID: 4818683] - T Saito, T Sugimura. Interaction of N-methyl-N'-nitro-N-nitrosoguanidine with DNA and histone in rat tissues in vivo.
Gan.
1973 Dec; 64(6):537-43. doi:
NULL. [PMID: 4779856] - C Heidelberger. Current trends in chemical carcinogenesis.
Federation proceedings.
1973 Dec; 32(12):2154-61. doi:
". [PMID: 4585036] - C H Davis, R H Rothman. Induction of crown gall by nitrosoguanidine-treated Agrobacterium tumefaciens.
Mutation research.
1973 Nov; 20(2):283-5. doi:
10.1016/0027-5107(73)90200-5. [PMID: 4753932] - E K Dhillon, T S Dhillon. HK239: a P2 related temperate phage which excludes rII mutants of T4.
Virology.
1973 Sep; 55(1):136-42. doi:
10.1016/s0042-6822(73)81015-3. [PMID: 4580728] - D E Bradway, T M Shafik. Parathion exposure studies. A gas chromatographic method for the determination of low levels of p-nitrophenol in human and animal urine.
Bulletin of environmental contamination and toxicology.
1973 Mar; 9(3):134-9. doi:
10.1007/bf01684992. [PMID: 4781689] - L O Ingram, W D Fisher. Novel mutant impaired in cell division: evidence for a positive regulating factor.
Journal of bacteriology.
1973 Feb; 113(2):999-1005. doi:
10.1128/jb.113.2.999-1005.1973. [PMID: 4632328] - L O Ingram, W D Fisher. Mechanism for the regulation of cell division in Agmenellum.
Journal of bacteriology.
1973 Feb; 113(2):1006-14. doi:
10.1128/jb.113.2.1006-1014.1973. [PMID: 4632309] - M Jerkofsky, F Rapp. Host cell DNA synthesis as a possible factor in the enhancement of replication of human adenoviruses in simian cells by SV40.
Virology.
1973 Feb; 51(2):466-73. doi:
10.1016/0042-6822(73)90445-5. [PMID: 4348305] - Y A Hamdi. Swelling forms on roots of berseem-clover (Trifolium alexandrinum), caused by a strain of Rhizobium trifolii.
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie.
1973; 128(5):532-7. doi:
10.1016/s0044-4057(73)80074-7. [PMID: 4801559] - D M Livingston, G J Todaro. Murine sarcoma virus-transformed nonproducer rat cell lines resistant to type C-virus infection.
Intervirology.
1973; 1(5-6):329-37. doi:
10.1159/000148861. [PMID: 4131817] - G F Babcock, D L Berryhill, D H Marsh. R-factors of Escherichia coli from dressed beef and humans.
Applied microbiology.
1973 Jan; 25(1):21-3. doi:
10.1128/am.25.1.21-23.1973. [PMID: 4119830] - U P Singh. Chemical mutagenesis in Taphrina maculans Butler. I. Survival and mutation induction by N-methyl-N'-nitro-N-nitrosoguanidine.
Zeitschrift fur allgemeine Mikrobiologie.
1973; 13(2):161-6. doi:
". [PMID: 4581214] - H K Meiss, C Basilico. Temperature sensitive mutants of BHK 21 cells.
Nature: New biology.
1972 Sep; 239(90):66-8. doi:
10.1038/newbio239066a0. [PMID: 4267115] - M Takahashi. Isolation of conditional lethal mutants (temperature sensitive and host-dependent mutants) of adenovirus type 5.
Virology.
1972 Sep; 49(3):815-7. doi:
10.1016/0042-6822(72)90540-5. [PMID: 4672419] - G Kimura, R Dulbecco. Isolation and characterization of temperature-sensitive mutants of simian virus 40.
Virology.
1972 Aug; 49(2):394-403. doi:
10.1016/0042-6822(72)90492-8. [PMID: 4340807] - M Oki, O Doi, S Nojima. Mutant of Escherichia coli K-12 deficient for detergent-resistant phospholipase A.
Journal of bacteriology.
1972 Jun; 110(3):864-9. doi:
10.1128/jb.110.3.864-869.1972. [PMID: 4555415] - B Starościak, J Nalecz, W T Dobrzański. Transformation in group H streptococci: blackburn strain transformable mutants.
Journal of bacteriology.
1972 May; 110(2):764-5. doi:
10.1128/jb.110.2.764-765.1972. [PMID: 5063215] - H C Renger, C Basilico. Mutation causing temperature-sensitive expression of cell transformation by a tumor virus (SV40-3T3 mouse cells-growth control).
Proceedings of the National Academy of Sciences of the United States of America.
1972 Jan; 69(1):109-14. doi:
10.1073/pnas.69.1.109. [PMID: 4109594] - B Simizu, N Takayama. Virulence of a temperature-sensitive mutant of western equine encephalitis virus.
Archiv fur die gesamte Virusforschung.
1972; 38(4):328-37. doi:
10.1007/bf01262823. [PMID: 5083407] - S H Orkin, J W Littlefield. Mutagenesis to aminopterin resistance in cultured hamster cells.
Experimental cell research.
1971 Nov; 69(1):174-80. doi:
10.1016/0014-4827(71)90322-3. [PMID: 5166371] - P Tegtmeyer, H L Ozer. Temperature-sensitive mutants of simian virus 40: infection of permissive cells.
Journal of virology.
1971 Oct; 8(4):516-24. doi:
10.1128/jvi.8.4.516-524.1971. [PMID: 4331655] - NULL. From nitrosamines to nitrosoureas and nitrosoquanidines.
Food and cosmetics toxicology.
1971 Oct; 9(5):719-24. doi:
10.1016/0015-6264(71)90167-2. [PMID: 4947687] - A Tanaka, T Sano. Metabolism of N-methyl-N'-nitro-N-nitrosoguanidine in rats.
Experientia.
1971 Sep; 27(9):1007-8. doi:
10.1007/bf02138845. [PMID: 4940284] - U Lundholm, W Doerfler. Temperature-sensitive mutants of human adenovirus type 12.
Virology.
1971 Sep; 45(3):827-9. doi:
10.1016/0042-6822(71)90206-6. [PMID: 5125575] - J L Beebe. Isolation and characterization of a phosphatidylethanolamine-deficient mutnt of Bacillus subtilis.
Journal of bacteriology.
1971 Sep; 107(3):704-11. doi:
10.1128/jb.107.3.704-711.1971. [PMID: 4999411] - A Forsgren, K Nordström, L Philipson, J Sjöquist. Protein A mutants of Staphylococcus aureus.
Journal of bacteriology.
1971 Jul; 107(1):245-50. doi:
10.1128/jb.107.1.245-250.1971. [PMID: 4254663] - J J Roberts, J M Pascoe, J E Plant, J E Sturrock, A R Crathorn. Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells. I. The effect on HeLa and Chinese hamster cell survival of alkylation of cellular macromolecules.
Chemico-biological interactions.
1971 Feb; 3(1):29-47. doi:
10.1016/0009-2797(71)90024-x. [PMID: 5156325] - Y Asato, C E Folsome. Temporal genetic mapping of the blue-green alga, Anacystis nidulans.
Genetics.
1970 Jul; 65(3):407-19. doi:
10.1093/genetics/65.3.407. [PMID: 4326453] - A J MUELLER, T GICHNER. MUTAGENIC ACTIVITY OF 1-METHYL-3-NITRO-1-NITROSOGUANIDINE ON ARABIDOPSIS.
Nature.
1964 Mar; 201(?):1149-50. doi:
10.1038/2011149b0. [PMID: 14152812]