N-Methylthiourea (BioDeep_00000720771)

   

Volatile Flavor Compounds


代谢物信息卡片


N-Methylthiourea

化学式: C2H6N2S (90.0251676)
中文名称: N-甲硫脲, N-甲基硫脲
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CNC(=S)N
InChI: InChI=1S/C2H6N2S/c1-4-2(3)5/h1H3,(H3,3,4,5)

描述信息

A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a methyl group.

同义名列表

2 个代谢物同义名

N-Methylthiourea; N-Methylthiourea



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Reza Heidari, Hossein Babaei, Mohammad Eghbal. Mechanisms of methimazole cytotoxicity in isolated rat hepatocytes. Drug and chemical toxicology. 2013 Oct; 36(4):403-11. doi: 10.3109/01480545.2012.749272. [PMID: 23256569]
  • Yesim Oztas, Bulent Uysal, Umit Kaldirim, Yavuz Poyrazoglu, Mehmet Yasar, Tuncer Cayci, Yavuz Cekli, Serdar Sadir, Mehmet Ozler, Turgut Topal, Sukru Oter, Ahmet Korkmaz. Inhibition of iNOS reduces the therapeutic effects of ozone in acute necrotizing pancreatitis: an in vivo animal study. Scandinavian journal of clinical and laboratory investigation. 2011 Sep; 71(5):370-7. doi: 10.3109/00365513.2011.572183. [PMID: 21463160]
  • Beatriz E Linares-Fernández, Anna B Alfieri. Cyclophosphamide induced cystitis: role of nitric oxide synthase, cyclooxygenase-1 and 2, and NK(1) receptors. The Journal of urology. 2007 Apr; 177(4):1531-6. doi: 10.1016/j.juro.2006.11.072. [PMID: 17382773]
  • A B Alfieri, A Malave, L X Cubeddu. Nitric oxide synthases and cyclophosphamide-induced cystitis in rats. Naunyn-Schmiedeberg's archives of pharmacology. 2001 Mar; 363(3):353-7. doi: 10.1007/s002100000371. [PMID: 11284451]
  • T Mizutani, K Yoshida, M Murakami, M Shirai, S Kawazoe. Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies. Chemical research in toxicology. 2000 Mar; 13(3):170-6. doi: 10.1021/tx990155o. [PMID: 10725113]
  • M Yabuki, J Shimakura, M Ito, H Kanamaru, K Iba, I Nakatsuka. Metabolism of 4-[1-(2-fluoro-4-biphenylyl)ethyl]-2-methylaminothiazole (SM-8849) in rats. European journal of drug metabolism and pharmacokinetics. 1997 Jan; 22(1):25-33. doi: 10.1007/bf03189781. [PMID: 9179557]
  • S P Gorman, D F McCafferty, A D Woolfson, L Anderson. Decrease in adherence of bacteria and yeasts to human mucosal epithelial cells by noxythiolin in vitro. The Journal of applied bacteriology. 1986 Apr; 60(4):311-7. doi: 10.1111/j.1365-2672.1986.tb01738.x. [PMID: 3087930]
  • D Debruyne, M A Moulin, H Bricard, M C Bigot. Liquid chromatographic determination of noxytiolin and 1-methyl-2-thiourea in serum: application to pharmacokinetic studies in rabbits and humans. Journal of pharmaceutical sciences. 1985 Feb; 74(2):224-6. doi: 10.1002/jps.2600740227. [PMID: 3921689]
  • A R Jones, P M Mashford. The fate of N-methyl-N'-(hydroxymethyl)thiourea in the rat. Xenobiotica; the fate of foreign compounds in biological systems. 1983 Feb; 13(2):73-9. doi: 10.3109/00498258309052239. [PMID: 6410593]
  • H Kobayashi, M Kaneda, S Teramoto. Identification of 1-methylthiourea as the metabolite of ethylenethiourea in rats by high-performance liquid chromatography. Toxicology letters. 1982 Jul; 12(2-3):109-13. doi: 10.1016/0378-4274(82)90172-2. [PMID: 6810507]