Y-27632 (BioDeep_00000720011)
代谢物信息卡片
(R)-trans-4-(1-Aminoethyl)-N-(4-pyridyl) cyclohexanecarboxamide
化学式: C14H21N3O (247.1684536)
中文名称: Y-27632二盐酸盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N
InChI: InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11?,12?/m1/s1
描述信息
D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002491 - Central Nervous System Agents
D004791 - Enzyme Inhibitors
同义名列表
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:92773
- ChEBI: CHEBI:75393
- PubChem: 448042
- DrugBank: DB08756
- ChEMBL: CHEMBL1083134
- ChEMBL: CHEMBL1188380
- ChEMBL: CHEMBL559147
- CAS: 146986-50-7
- CAS: 521059-79-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Linfeng Qian, Jiaxi Yan, Shiqi Chen, Maryam Mohanmmed Abbas Karekad, Yue Wu, Xunwei Wu, Xiaohong Xu, Xiaoqun Zhang. Isolation and Culture of Primary Human Mammary Epithelial Cells.
Journal of visualized experiments : JoVE.
2024 May; ?(207):. doi:
10.3791/66638. [PMID: 38767371] - Xiuhua Yin, Li Chen, Fanwei Meng, Ying Jiang. [Differentiated embryonic chondrocyte gene 2 (DEC2) inhibits transdifferentiation of mouse glomerular endothelial cells and renal fibrosis by blocking TGF-β/ROCK1 signaling pathway].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2023 Sep; 39(9):816-823. doi:
. [PMID: 37732577] - Mohammad Amir Mishan, Sahar Balagholi, Tahereh Chamani, Sepehr Feizi, Zahra-Soheila Soheili, Mozhgan Rezaei Kanavi. Comparative culture of human corneal endothelial cells following treatment with human platelet lysate/fibrin hydrogel versus Y-27632 ROCK inhibitor: in vitro and ex vivo study.
International ophthalmology.
2022 May; 42(5):1469-1479. doi:
10.1007/s10792-021-02136-x. [PMID: 35023011] - Zhiwei Xie, Qiuping Xu, Lu Sun, Ruijing Li, Jizhou Shi, Qian Yang, Min Zong, Jianyong Qin. Effects of Y-27632 on the osteogenic and adipogenic potential of human dental pulp stem cells in vitro.
Human & experimental toxicology.
2022 Jan; 41(?):9603271221089003. doi:
10.1177/09603271221089003. [PMID: 35388712] - Yifan Yang, Jing Xu, Qingxin Su, Yiran Wu, Qizheng Li, Zongren Ma, Tao Ding. Lysophosphatidic Acid Induced Apoptosis, DNA Damage, and Oxidative Stress in Spinal Cord Neurons by Upregulating LPA4/LPA6 Receptors.
Mediators of inflammation.
2022; 2022(?):1818758. doi:
10.1155/2022/1818758. [PMID: 36248188] - Fabiola González-Herrera, Natasha S Clayton, Daniela Guzmán-Rivera, Ileana Carrillo, Christian Castillo, Mabel Catalán, Renatto Anfossi, Helena Quintero-Pertuz, María Elena Quilaqueo, Claudio Olea-Azar, Mario Rivera-Meza, Ulrike Kemmerling, Anne J Ridley, Raúl Vivar, Juan Diego Maya. Statins change the cytokine profile in Trypanosoma cruzi-infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition.
Frontiers in immunology.
2022; 13(?):1035589. doi:
10.3389/fimmu.2022.1035589. [PMID: 36713380] - Jing Chen, Wenbin Shi, Yan Xu, Huaming Zhang, Bo Chen. Hirudin prevents vascular endothelial cell apoptosis and permeability enhancement induced by the serum from rat with chronic renal failure through inhibiting RhoA/ROCK signaling pathway.
Drug development research.
2021 06; 82(4):553-561. doi:
10.1002/ddr.21773. [PMID: 33345328] - Giulia Stefania Tavanti, Chiara Verdelli, Annamaria Morotti, Paola Maroni, Vito Guarnieri, Alfredo Scillitani, Rosamaria Silipigni, Silvana Guerneri, Riccardo Maggiore, Gilberto Mari, Leonardo Vicentini, Paolo Dalino Ciaramella, Valentina Vaira, Sabrina Corbetta. Yes-Associated Protein 1 Is a Novel Calcium Sensing Receptor Target in Human Parathyroid Tumors.
International journal of molecular sciences.
2021 Feb; 22(4):. doi:
10.3390/ijms22042016. [PMID: 33670622] - Weijie Zhang, Chunyi Shao, Fei Yu, Junzhao Chen, Yao Fu, Xianqun Fan. Y-27632 Promotes the Repair Effect of Umbilical Cord Blood-Derived Endothelial Progenitor Cells on Corneal Endothelial Wound Healing.
Cornea.
2021 Feb; 40(2):203-214. doi:
10.1097/ico.0000000000002560. [PMID: 33086282] - Jianchun Chen, Xiaoyong Wang, Qian He, Nada Bulus, Agnes B Fogo, Ming-Zhi Zhang, Raymond C Harris. YAP Activation in Renal Proximal Tubule Cells Drives Diabetic Renal Interstitial Fibrogenesis.
Diabetes.
2020 11; 69(11):2446-2457. doi:
10.2337/db20-0579. [PMID: 32843569] - Xuefeng Liu, Abdul M Mondal. Conditional cell reprogramming for modeling host-virus interactions and human viral diseases.
Journal of medical virology.
2020 11; 92(11):2440-2452. doi:
10.1002/jmv.26093. [PMID: 32478897] - Qing Ye, Sheng Zhao, Yu Zhang, Yi-Ming Su, Min Chen, Jing Zhao, Gao-Zhen Jia, Bang-Min Han, Jun-Tao Jiang. Activation of the RhoA/ROCK pathway contributes to renal fibrosis in offspring rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology.
2020 10; 443(?):152573. doi:
10.1016/j.tox.2020.152573. [PMID: 32860865] - Yifan Wang, Xueyun Duan, Xingxing Liu, Yujin Liu, Heng Fan, Meng Xu, Qianyun Chen, Qing Tang. Rho kinase Blockade Ameliorates DSS-Induced Ulcerative Colitis in Mice Through Dual Inhibition of the NF-κB and IL-6/STAT3 Pathways.
Inflammation.
2020 Jun; 43(3):857-867. doi:
10.1007/s10753-019-01171-2. [PMID: 31916050] - Christie Buonpane, Carrie Yuan, Douglas Wood, Guillermo Ares, Samuel C Klonoski, Catherine J Hunter. ROCK1 inhibitor stabilizes E-cadherin and improves barrier function in experimental necrotizing enterocolitis.
American journal of physiology. Gastrointestinal and liver physiology.
2020 04; 318(4):G781-G792. doi:
10.1152/ajpgi.00195.2019. [PMID: 32090605] - Yusuke Isozaki, Kouki Sakai, Kenta Kohiro, Katsuhiko Kagoshima, Yuma Iwamura, Hironori Sato, Daniel Rindner, Sachiko Fujiwara, Kazunari Yamashita, Kensaku Mizuno, Kazumasa Ohashi. The Rho-guanine nucleotide exchange factor Solo decelerates collective cell migration by modulating the Rho-ROCK pathway and keratin networks.
Molecular biology of the cell.
2020 04; 31(8):741-752. doi:
10.1091/mbc.e19-07-0357. [PMID: 32049581] - Shigeo Wakabayashi, Hirofumi Morihara, Shunichi Yokoe, Takatoshi Nakagawa, Kazumasa Moriwaki, Kiichiro Tomoda, Michio Asahi. Overexpression of Na+/H+ exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK.
The Journal of biological chemistry.
2019 12; 294(51):19577-19588. doi:
10.1074/jbc.ra119.010329. [PMID: 31723030] - Cecília R Panta, Éva Ruisanchez, Dorottya Móré, Péter T Dancs, Andrea Balogh, Ágnes Fülöp, Margit Kerék, Richard L Proia, Stefan Offermanns, Gábor J Tigyi, Zoltán Benyó. Sphingosine-1-Phosphate Enhances α1-Adrenergic Vasoconstriction via S1P2-G12/13-ROCK Mediated Signaling.
International journal of molecular sciences.
2019 Dec; 20(24):. doi:
10.3390/ijms20246361. [PMID: 31861195] - Matthew Koslow, Kevin J O'Keefe, Zeinab F Hosseini, Deirdre A Nelson, Melinda Larsen. ROCK inhibitor increases proacinar cells in adult salivary gland organoids.
Stem cell research.
2019 12; 41(?):101608. doi:
10.1016/j.scr.2019.101608. [PMID: 31731180] - Zhengrong Guan, Joshua J Baty, Shali Zhang, Colton E Remedies, Edward W Inscho. Rho kinase inhibitors reduce voltage-dependent Ca2+ channel signaling in aortic and renal microvascular smooth muscle cells.
American journal of physiology. Renal physiology.
2019 11; 317(5):F1132-F1141. doi:
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Biochemical and biophysical research communications.
2019 10; 519(1):134-140. doi:
10.1016/j.bbrc.2019.08.149. [PMID: 31477271] - Nancy Palechor-Ceron, Ewa Krawczyk, Aleksandra Dakic, Vera Simic, Hang Yuan, Jan Blancato, Weisheng Wang, Fleesie Hubbard, Yun-Ling Zheng, Hancai Dan, Scott Strome, Kevin Cullen, Bruce Davidson, John F Deeken, Sujata Choudhury, Peter H Ahn, Seema Agarwal, Xuexun Zhou, Richard Schlegel, Priscilla A Furth, Chong-Xian Pan, Xuefeng Liu. Conditional Reprogramming for Patient-Derived Cancer Models and Next-Generation Living Biobanks.
Cells.
2019 10; 8(11):. doi:
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Aging cell.
2019 10; 18(5):e13001. doi:
10.1111/acel.13001. [PMID: 31287605] - Yifan Wang, Zhexing Shou, Heng Fan, Meng Xu, Qianyun Chen, Qing Tang, Xingxing Liu, Hui Wu, Man Zhang, Ting Yu, Shuangjiao Deng, Yujin Liu. Protective effects of oxymatrine against DSS-induced acute intestinal inflammation in mice via blocking the RhoA/ROCK signaling pathway.
Bioscience reports.
2019 07; 39(7):. doi:
10.1042/bsr20182297. [PMID: 31262973] - Shou Tanaka, Noriko Ishihara, Sawako Suzuki, Yasuhiro Watanabe, Daiji Nagayama, Takashi Yamaguchi, Masahiro Ohira, Atsuhito Saiki, Tomoaki Tanaka, Ichiro Tatsuno. Fatty acid desaturase 2 is up-regulated by the treatment with statin through geranylgeranyl pyrophosphate-dependent Rho kinase pathway in HepG2 cells.
Scientific reports.
2019 07; 9(1):10009. doi:
10.1038/s41598-019-46461-9. [PMID: 31292513] - Wei Chen, Hong Xiang, Ruifang Chen, Jie Yang, Xiaoping Yang, Jianda Zhou, Hengdao Liu, Shaoli Zhao, Jie Xiao, Pan Chen, Alex F Chen, Shuhua Chen, Hongwei Lu. S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1.
BMC nephrology.
2019 04; 20(1):135. doi:
10.1186/s12882-019-1323-0. [PMID: 30999892] - Xue-Ying Wang, Dan Mo, Wen Tian, Xiao-Xiao Liu, Ya-Guang Zhou, Yang Sun, Ying-Da Feng, Xiong Xiao, Xiao-Wei Hao, Hui-Nan Zhang, Chen Li, Wei Cao, Xiao-Qiang Li. Inhibition of RhoA/ROCK signaling pathway ameliorates hypoxic pulmonary hypertension via HIF-1α-dependent functional TRPC channels.
Toxicology and applied pharmacology.
2019 04; 369(?):60-72. doi:
10.1016/j.taap.2019.02.017. [PMID: 30831131] - Li-Ya Dong, Xiao-Xiao Qiu, Yu Zhuang, Song Xue. Y-27632, a Rho-kinase inhibitor, attenuates myocardial ischemia-reperfusion injury in rats.
International journal of molecular medicine.
2019 Apr; 43(4):1911-1919. doi:
10.3892/ijmm.2019.4097. [PMID: 30816436] - F van Dijk, N Teekamp, E Post, D Schuppan, Y O Kim, J Zuidema, R Steendam, Matthias H M Klose, Samuel M Meier-Menches, A Casini, P L Horvatovich, N J Sijbrandi, H W Frijlink, W L J Hinrichs, K Poelstra, L Beljaars, P Olinga. The antifibrotic potential of a sustained release formulation of a PDGFβ-receptor targeted rho kinase inhibitor.
Journal of controlled release : official journal of the Controlled Release Society.
2019 02; 296(?):250-257. doi:
10.1016/j.jconrel.2018.12.039. [PMID: 30682444] - Sabine Klein, Franziska Frohn, Fernando Magdaleno, Catharina Reker-Smit, Robert Schierwagen, Irela Schierwagen, Frank Erhard Uschner, Fransien van Dijk, Dieter O Fürst, Sonja Djudjaj, Peter Boor, Klaas Poelstra, Leonie Beljaars, Jonel Trebicka. Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats.
Scientific reports.
2019 02; 9(1):2256. doi:
10.1038/s41598-019-38678-5. [PMID: 30783172] - Soojung Hahn, Mi Sun Kim, Seon Young Choi, Sukin Jeong, JooHyun Jee, Han Kyung Kim, Sang Yun Jeong, Hyunsoo Shin, Hyoung Sun Kim, Joon Seong Park, Jongman Yoo. Leucine-rich repeat-containing G-protein coupled receptor 5 enriched organoids under chemically-defined growth conditions.
Biochemical and biophysical research communications.
2019 01; 508(2):430-439. doi:
10.1016/j.bbrc.2018.11.003. [PMID: 30503340] - Shimeng Guo, Shichao Liu, Gerelchimeg Bou, Jia Guo, Liyuan Jiang, Zhuang Chai, Mingming Cai, Yanshuang Mu, Zhonghua Liu. Fetal bovine serum promotes the development of in vitro porcine blastocysts by activating the Rho-associated kinase signalling pathway.
Reproduction, fertility, and development.
2019 Jan; 31(2):366-376. doi:
10.1071/rd18070. [PMID: 30253120] - Jens C Hamann, Sung Eun Kim, Michael Overholtzer. Methods for the Study of Entotic Cell Death.
Methods in molecular biology (Clifton, N.J.).
2019; 1880(?):447-454. doi:
10.1007/978-1-4939-8873-0_28. [PMID: 30610714] - Natalia Petersen, Thomas M Frimurer, Marianne Terndrup Pedersen, Kristoffer L Egerod, Nicolai J Wewer Albrechtsen, Jens J Holst, Anne Grapin-Botton, Kim B Jensen, Thue W Schwartz. Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine.
Gastroenterology.
2018 10; 155(4):1164-1176.e2. doi:
10.1053/j.gastro.2018.06.039. [PMID: 29935151] - Julia Dolinina, Anna Rippe, Peter Bentzer, Carl M Öberg. Glomerular hyperpermeability after acute unilateral ureteral obstruction: effects of Tempol, NOS, RhoA, and Rac-1 inhibition.
American journal of physiology. Renal physiology.
2018 09; 315(3):F445-F453. doi:
10.1152/ajprenal.00610.2017. [PMID: 29465305] - Liming Wang, Anne F Buckley, Robert F Spurney. Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1).
Scientific reports.
2018 08; 8(1):12286. doi:
10.1038/s41598-018-30115-3. [PMID: 30115939] - Mustafa Onur Oztan, Sule Oztan, Neslihan Duzenli, Murat Olukman, Gokhan Koyluoglu. The effect of platelet-rich plasma on motility changes in experimental caustic esophageal burn.
Esophagus : official journal of the Japan Esophageal Society.
2018 07; 15(3):198-204. doi:
10.1007/s10388-018-0613-0. [PMID: 29951983] - Anna Klinke, Eva Berghausen, Kai Friedrichs, Simon Molz, Denise Lau, Lisa Remane, Matthias Berlin, Charlotte Kaltwasser, Matti Adam, Dennis Mehrkens, Martin Mollenhauer, Kashish Manchanda, Thorben Ravekes, Gustavo A Heresi, Metin Aytekin, Raed A Dweik, Jan K Hennigs, Lukas Kubala, Erik Michaëlsson, Stephan Rosenkranz, Tanja K Rudolph, Stanley L Hazen, Hans Klose, Ralph T Schermuly, Volker Rudolph, Stephan Baldus. Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.
JCI insight.
2018 06; 3(11):. doi:
10.1172/jci.insight.97530. [PMID: 29875311] - Duy Trong Vien Diep, Kyungki Hong, Triyeng Khun, Mei Zheng, Asad Ul-Haq, Hee-Sook Jun, Young-Bum Kim, Kwang-Hoon Chun. Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells.
Scientific reports.
2018 02; 8(1):2477. doi:
10.1038/s41598-018-20821-3. [PMID: 29410516] - Giuseppe Faraco, David Brea, Lidia Garcia-Bonilla, Gang Wang, Gianfranco Racchumi, Haejoo Chang, Izaskun Buendia, Monica M Santisteban, Steven G Segarra, Kenzo Koizumi, Yukio Sugiyama, Michelle Murphy, Henning Voss, Joseph Anrather, Costantino Iadecola. Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response.
Nature neuroscience.
2018 02; 21(2):240-249. doi:
10.1038/s41593-017-0059-z. [PMID: 29335605] - Jie Wen, Tingjian Zu, Qian Zhou, Xue Leng, Xunwei Wu. Y-27632 simplifies the isolation procedure of human primary epidermal cells by selectively blocking focal adhesion of dermal cells.
Journal of tissue engineering and regenerative medicine.
2018 02; 12(2):e1251-e1255. doi:
10.1002/term.2526. [PMID: 28752652] - Solomon L Woldu, Ryan C Hutchinson, Laura-Maria Krabbe, Oner Sanli, Vitaly Margulis. The Rho GTPase signalling pathway in urothelial carcinoma.
Nature reviews. Urology.
2018 02; 15(2):83-91. doi:
10.1038/nrurol.2017.184. [PMID: 29133936] - Ting Wang, Wenyan Kang, Lingqian Du, Shaohua Ge. Rho-kinase inhibitor Y-27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells.
Journal of cellular and molecular medicine.
2017 Nov; 21(11):3100-3112. doi:
10.1111/jcmm.13222. [PMID: 28661039] - Deepika Verma, Vivek K Bajpai, Nannan Ye, Mohammad M Maneshi, Deekshitha Jetta, Stelios T Andreadis, Frederick Sachs, Susan Z Hua. Flow induced adherens junction remodeling driven by cytoskeletal forces.
Experimental cell research.
2017 10; 359(2):327-336. doi:
10.1016/j.yexcr.2017.08.009. [PMID: 28803065] - Noriko Ishihara, Sawako Suzuki, Shou Tanaka, Yasuhiro Watanabe, Daiji Nagayama, Atsuhito Saiki, Tomoaki Tanaka, Ichiro Tatsuno. Atorvastatin increases Fads1, Fads2 and Elovl5 gene expression via the geranylgeranyl pyrophosphate-dependent Rho kinase pathway in 3T3-L1 cells.
Molecular medicine reports.
2017 Oct; 16(4):4756-4762. doi:
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Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2017 Jul; 33(7):875-880. doi:
NULL. [PMID: 28712392] - Yuanyuan Wang, Yang Lu, Jixia Chai, Meiqun Sun, Xiaodong Hu, Wenxin He, Min Ge, Changhao Xie. Y-27632, a Rho-associated protein kinase inhibitor, inhibits systemic lupus erythematosus.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Apr; 88(?):359-366. doi:
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Oncogene.
2017 02; 36(8):1080-1089. doi:
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Scientific reports.
2017 01; 7(?):39727. doi:
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PloS one.
2017; 12(9):e0184595. doi:
10.1371/journal.pone.0184595. [PMID: 28886159] - Ning Zhou, Jia-Jye Lee, Shaunrick Stoll, Ben Ma, Kevin D Costa, Hongyu Qiu. Rho Kinase Regulates Aortic Vascular Smooth Muscle Cell Stiffness Via Actin/SRF/Myocardin in Hypertension.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2017; 44(2):701-715. doi:
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The journal of sexual medicine.
2016 12; 13(12):1858-1871. doi:
10.1016/j.jsxm.2016.10.007. [PMID: 27914563] - Zen-Kong Dai, Chang-Ling Kao, Su-Ling Hsieh, Ing-Jun Chen, Bin-Nan Wu. Restoration of uridine 5'-triphosphate-suppressed delayed rectifying K+ currents by an NO activator KMUP-1 involves RhoA/Rho kinase signaling in pulmonary artery smooth muscle cells.
The Kaohsiung journal of medical sciences.
2016 Dec; 32(12):607-613. doi:
10.1016/j.kjms.2016.09.008. [PMID: 27914611] - Renyu Ding, Jiali Han, Dongmei Zhao, Ziwei Hu, Xiaochun Ma. Pretreatment with Rho-kinase inhibitor ameliorates lethal endotoxemia-induced liver injury by improving mitochondrial function.
International immunopharmacology.
2016 Nov; 40(?):125-130. doi:
10.1016/j.intimp.2016.08.036. [PMID: 27588912] - Nicholas Mitrou, Branko Braam, William A Cupples. A gap junction inhibitor, carbenoxolone, induces spatiotemporal dispersion of renal cortical perfusion and impairs autoregulation.
American journal of physiology. Heart and circulatory physiology.
2016 09; 311(3):H582-91. doi:
10.1152/ajpheart.00941.2015. [PMID: 27371687] - Bruns A Watts, Thampi George, Andrew Badalamenti, David W Good. High-mobility group box 1 inhibits HCO3- absorption in the medullary thick ascending limb through RAGE-Rho-ROCK-mediated inhibition of basolateral Na+/H+ exchange.
American journal of physiology. Renal physiology.
2016 09; 311(3):F600-13. doi:
10.1152/ajprenal.00185.2016. [PMID: 27358052] - Rong-Shan Li, Yong Wang, Hui-Shen Chen, Fang-Yong Jiang, Qiang Tu, Wen-Jun Li, Rui-Xing Yin. TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway.
Molecular medicine reports.
2016 Apr; 13(4):3691-9. doi:
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Nature communications.
2016 Feb; 7(?):10656. doi:
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Advanced healthcare materials.
2016 Jan; 5(1):146-58. doi:
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Methods in molecular biology (Clifton, N.J.).
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Methods in molecular biology (Clifton, N.J.).
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Molecular medicine reports.
2015 Nov; 12(5):7310-6. doi:
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European journal of pharmacology.
2015 Oct; 764(?):318-327. doi:
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Experimental and molecular pathology.
2015 Oct; 99(2):220-8. doi:
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Cellular and molecular life sciences : CMLS.
2015 Aug; 72(16):3157-71. doi:
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Scientific reports.
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Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2015 May; 35(5):835-42. doi:
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Biochemical and biophysical research communications.
2015 May; 460(2):123-9. doi:
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Cell biology international.
2015 May; 39(5):563-76. doi:
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American journal of physiology. Renal physiology.
2015 Apr; 308(8):F899-909. doi:
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Cytokine.
2015 Apr; 72(2):130-4. doi:
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Journal of anesthesia.
2015 Apr; 29(2):186-90. doi:
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Journal of biomechanics.
2015 Feb; 48(4):627-635. doi:
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European journal of pharmacology.
2015 Jan; 746(?):186-97. doi:
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International journal of medical sciences.
2015; 12(12):958-67. doi:
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PloS one.
2015; 10(11):e0142442. doi:
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Biological & pharmaceutical bulletin.
2015; 38(5):732-9. doi:
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Cell transplantation.
2015; 24(9):1845-61. doi:
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Current cancer drug targets.
2015; 15(3):205-14. doi:
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American journal of physiology. Heart and circulatory physiology.
2014 Dec; 307(12):H1764-76. doi:
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Theriogenology.
2014 Jul; 82(1):49-56. doi:
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Critical care medicine.
2014 Jun; 42(6):e461-71. doi:
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Integrative biology : quantitative biosciences from nano to macro.
2014 Apr; 6(4):411-21. doi:
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Journal of neuroscience research.
2014 Apr; 92(4):455-63. doi:
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Integrative biology : quantitative biosciences from nano to macro.
2014 Mar; 6(3):267-76. doi:
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Pharmacological reports : PR.
2014 Feb; 66(1):114-20. doi:
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European journal of pharmacology.
2014 Jan; 723(?):234-45. doi:
10.1016/j.ejphar.2013.11.027. [PMID: 24296316] - Mihwa Kim, Ahrom Ham, Katelyn Yu-Mi Kim, Kevin M Brown, H Thomas Lee. The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
PloS one.
2014; 9(6):e99950. doi:
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PloS one.
2014; 9(9):e107308. doi:
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PloS one.
2014; 9(12):e114249. doi:
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Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.
2014; 50(?):103-19. doi:
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Asian Pacific journal of cancer prevention : APJCP.
2014; 15(22):9593-7. doi:
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PloS one.
2014; 9(5):e96548. doi:
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PloS one.
2014; 9(3):e91346. doi:
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Bioorganic & medicinal chemistry letters.
2013 Dec; 23(23):6442-6. doi:
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Phytotherapy research : PTR.
2013 Sep; 27(9):1308-12. doi:
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Journal of cell science.
2013 Sep; 126(Pt 17):3873-83. doi:
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Burns : journal of the International Society for Burn Injuries.
2013 Aug; 39(5):923-34. doi:
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Free radical biology & medicine.
2013 Aug; 61(?):26-39. doi:
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International journal of molecular medicine.
2013 Aug; 32(2):464-8. doi:
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