TPCA-1 (BioDeep_00000719810)
代谢物信息卡片
化学式: C12H10FN3O2S (279.0478)
中文名称: TPCA-1
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F
InChI: InChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)
描述信息
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Yin-Yin Chen, Han Hong, Yu-Ting Lei, Jia Zou, Yi-Ya Yang, Li-Yu He. IκB kinase promotes Nrf2 ubiquitination and degradation by phosphorylating cylindromatosis, aggravating oxidative stress injury in obesity-related nephropathy.
Molecular medicine (Cambridge, Mass.).
2021 10; 27(1):137. doi:
10.1186/s10020-021-00398-w. [PMID: 34711178] - InWha Park, Hee Sun Byun, Gang Min Hur, MinKyun Na. Tulipiferamide A, an Alkamide from Liriodendron tulipifera, Exhibits an Anti-Inflammatory Effect via Targeting IKKβ Phosphorylation.
Journal of natural products.
2021 05; 84(5):1598-1606. doi:
10.1021/acs.jnatprod.1c00146. [PMID: 33939429] - Qihao Sun, Yan Fu, Xuejun Zhu, Wen-Song Tan, Haibo Cai. Continuous NF-κB pathway inhibition promotes expansion of human phenotypical hematopoietic stem/progenitor cells through metabolism regulation.
Experimental cell research.
2021 02; 399(2):112468. doi:
10.1016/j.yexcr.2020.112468. [PMID: 33428903] - Yijun Zhou, Chaojun Qi, Shu Li, Xinghua Shao, Zhaohui Ni. Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose.
Mediators of inflammation.
2019; 2019(?):9893682. doi:
10.1155/2019/9893682. [PMID: 31780874] - Jielu Hao, Qiang Lou, Qingqing Wei, Shuqin Mei, Lin Li, Guangyu Wu, Qing-Sheng Mi, Changlin Mei, Zheng Dong. MicroRNA-375 Is Induced in Cisplatin Nephrotoxicity to Repress Hepatocyte Nuclear Factor 1-β.
The Journal of biological chemistry.
2017 03; 292(11):4571-4582. doi:
10.1074/jbc.m116.754929. [PMID: 28119452] - Lisa Baumgartner, Silvio Sosa, Atanas G Atanasov, Antje Bodensieck, Nanang Fakhrudin, Julia Bauer, Giorgia Del Favero, Cristina Ponti, Elke H Heiss, Stefan Schwaiger, Angela Ladurner, Ute Widowitz, Roberto Della Loggia, Judith M Rollinger, Oliver Werz, Rudolf Bauer, Verena M Dirsch, Aurelia Tubaro, Hermann Stuppner. Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro.
Journal of natural products.
2011 Aug; 74(8):1779-86. doi:
10.1021/np200343t. [PMID: 21800856]
