Amyloid β-Protein (25-35) trifluoroacetate salt (BioDeep_00000719699)
代谢物信息卡片
2-[[2-[[2-[[2-[[2-[2-[[2-[[6-Amino-2-[[4-amino-2-[[2-[(2-aminoacetyl)amino]-3-hydroxypropanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]amino]acetyl]amino]propanoylamino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid
化学式: C45H81N13O14S (1059.5746365999998)
中文名称: β-淀粉状蛋白25-35
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CN
InChI: InChI=1S/C45H81N13O14S/c1-9-24(5)36(43(69)50-21-35(63)52-29(17-23(3)4)40(66)55-28(45(71)72)14-16-73-8)58-44(70)37(25(6)10-2)57-38(64)26(7)51-34(62)20-49-39(65)27(13-11-12-15-46)54-41(67)30(18-32(48)60)56-42(68)31(22-59)53-33(61)19-47/h23-31,36-37,59H,9-22,46-47H2,1-8H3,(H2,48,60)(H,49,65)(H,50,69)(H,51,62)(H,52,63)(H,53,61)(H,54,67)(H,55,66)(H,56,68)(H,57,64)(H,58,70)(H,71,72)
描述信息
β-Amyloid (25-35) (Amyloid beta-peptide (25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells[1].
同义名列表
6 个代谢物同义名
2-[[2-[[2-[[2-[[2-[2-[[2-[[6-Amino-2-[[4-amino-2-[[2-[(2-aminoacetyl)amino]-3-hydroxypropanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]amino]acetyl]amino]propanoylamino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoic acid; Amyloid β-Protein (25-35) trifluoroacetate salt; Amyloid beta-peptide (25-35); Aβ25-35; β-Amyloid peptide (25-35); β-Amyloid (25-35)
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Huijuan Wang, Lifen Zhou, Qin Zheng, Yonggui Song, Weihua Huang, Lin Yang, Yongchang Xiong, Zhinan Cai, Ying Chen, Jinbin Yuan. Kai-xin-san improves cognitive impairment in D-gal and Aβ25-35 induced ad rats by regulating gut microbiota and reducing neuronal damage.
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155709. doi:
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Nutritional neuroscience.
2023 Aug; ?(?):1-16. doi:
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ACS chemical neuroscience.
2023 02; 14(3):494-505. doi:
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BioMed research international.
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Human & experimental toxicology.
2021 Dec; 40(12_suppl):S347-S358. doi:
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Scientific reports.
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ACS chemical neuroscience.
2021 09; 12(17):3225-3236. doi:
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Bioorganic chemistry.
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Cellular and molecular neurobiology.
2021 Mar; 41(2):377-393. doi:
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European journal of pharmacology.
2021 Feb; 893(?):173835. doi:
10.1016/j.ejphar.2020.173835. [PMID: 33359145] - Simon Couly, Morgane Denus, Mélanie Bouchet, Gilles Rubinstenn, Tangui Maurice. Anti-Amnesic and Neuroprotective Effects of Fluoroethylnormemantine in a Pharmacological Mouse Model of Alzheimer's Disease.
The international journal of neuropsychopharmacology.
2021 02; 24(2):142-157. doi:
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2021 02; 1863(2):183506. doi:
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Pharmaceutical biology.
2020 Dec; 58(1):35-43. doi:
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ACS chemical neuroscience.
2020 10; 11(20):3430-3441. doi:
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Journal of ethnopharmacology.
2020 Oct; 260(?):112783. doi:
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Scientific reports.
2020 10; 10(1):16424. doi:
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Journal of ethnopharmacology.
2020 Sep; 259(?):112940. doi:
10.1016/j.jep.2020.112940. [PMID: 32389853] - Oh Yun Kwon, Seung Ho Lee. Ameliorating Activity of Ishige okamurae on the Amyloid Beta-Induced Cognitive Deficits and Neurotoxicity through Regulating ERK, p38 MAPK, and JNK Signaling in Alzheimer's Disease-Like Mice Model.
Molecular nutrition & food research.
2020 Jun; 64(12):e1901220. doi:
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Pakistan journal of pharmaceutical sciences.
2020 May; 33(3(Special)):1427-1433. doi:
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Life sciences.
2020 May; 248(?):117471. doi:
10.1016/j.lfs.2020.117471. [PMID: 32112868] - Wenbin Wu, Xiaojing He, Shuling Xie, Bin Li, Jinxin Chen, Yanqin Qu, Baiyang Li, Ming Lei, Xuehui Liu. Protective effects of Huang-Lian-Jie-Du-Tang against Aβ25-35-induced memory deficits and oxidative stress in rats.
The Journal of international medical research.
2020 Mar; 48(3):300060519893859. doi:
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Drug design, development and therapy.
2020; 14(?):1705-1716. doi:
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Journal of chemical information and modeling.
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Planta medica.
2019 Nov; 85(17):1363-1373. doi:
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Biochemical and biophysical research communications.
2019 10; 518(3):438-444. doi:
10.1016/j.bbrc.2019.08.033. [PMID: 31447119] - Ji Hyun Kim, Sanghyun Lee, Eun Ju Cho. Acer okamotoanum and isoquercitrin improve cognitive function via attenuation of oxidative stress in high fat diet- and amyloid beta-induced mice.
Food & function.
2019 Oct; 10(10):6803-6814. doi:
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Molecules (Basel, Switzerland).
2019 Aug; 24(16):. doi:
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European journal of pharmacology.
2019 May; 851(?):69-79. doi:
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Scientific reports.
2019 05; 9(1):7161. doi:
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Neurochemistry international.
2019 05; 125(?):57-66. doi:
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Journal of dietary supplements.
2019; 16(5):491-505. doi:
10.1080/19390211.2018.1471563. [PMID: 29958039] - Lingrong Zeng, Jianmei Gao, Yuanyuan Deng, Jingshan Shi, Qihai Gong. CZ2HF mitigates β-amyloid 25-35 fragment-induced learning and memory impairment through inhibition of neuroinflammation and apoptosis in rats.
International journal of molecular medicine.
2019 Jan; 43(1):557-566. doi:
10.3892/ijmm.2018.3952. [PMID: 30365041] - Yuhui Wang, Jinyang Shen, Xiaolin Yang, Ye Jin, Zhonglin Yang, Rufeng Wang, Fuming Zhang, Robert J Linhardt. Akebia saponin D reverses corticosterone hypersecretion in an Alzheimer's disease rat model.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Sep; 105(?):1006-1014. doi:
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Neurotoxicology.
2018 09; 68(?):73-80. doi:
10.1016/j.neuro.2018.07.008. [PMID: 30031108] - Cong-Cong Guo, Chun-Hong Jiao, Zhen-Mei Gao. Silencing of LncRNA BDNF-AS attenuates Aβ25-35-induced neurotoxicity in PC12 cells by suppressing cell apoptosis and oxidative stress.
Neurological research.
2018 Sep; 40(9):795-804. doi:
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Food & function.
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2018 Aug; 50(?):160-171. doi:
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Journal of visualized experiments : JoVE.
2018 07; ?(137):. doi:
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Planta medica.
2018 Jul; 84(11):820-828. doi:
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International journal of biological macromolecules.
2018 Jul; 113(?):607-615. doi:
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Journal of ethnopharmacology.
2018 Jun; 219(?):182-194. doi:
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International journal of molecular sciences.
2018 Jun; 19(6):. doi:
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Journal of chemical information and modeling.
2018 05; 58(5):1053-1065. doi:
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Journal of agricultural and food chemistry.
2018 May; 66(19):4853-4861. doi:
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Journal of agricultural and food chemistry.
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CNS & neurological disorders drug targets.
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The American journal of Chinese medicine.
2018; 46(2):389-405. doi:
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Journal of agricultural and food chemistry.
2017 Dec; 65(49):10719-10729. doi:
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Pharmaceutical biology.
2017 Dec; 55(1):1423-1435. doi:
10.1080/13880209.2017.1302967. [PMID: 28320234] - Seonah Lee, Kumju Youn, Woo-Sik Jeong, Chi-Tang Ho, Mira Jun. Protective Effects of Red Ginseng Oil against Aβ25-35-Induced Neuronal Apoptosis and Inflammation in PC12 Cells.
International journal of molecular sciences.
2017 Oct; 18(10):. doi:
10.3390/ijms18102218. [PMID: 29065557] - Qing-Qing Fu, Li Wei, Javier Sierra, Jian-Zhang Cheng, María Teresa Moreno-Flores, Hua You, Hua-Rong Yu. Olfactory Ensheathing Cell-Conditioned Medium Reverts Aβ25-35-Induced Oxidative Damage in SH-SY5Y Cells by Modulating the Mitochondria-Mediated Apoptotic Pathway.
Cellular and molecular neurobiology.
2017 Aug; 37(6):1043-1054. doi:
10.1007/s10571-016-0437-1. [PMID: 27807758] - Vasudevan Mani, Siti Murnirah Jaafar, Nur Syamimi Mohd Azahan, Kalavathy Ramasamy, Siong Meng Lim, Long Chiau Ming, Abu Bakar Abdul Majeed. Ciproxifan improves cholinergic transmission, attenuates neuroinflammation and oxidative stress but does not reduce amyloid level in transgenic mice.
Life sciences.
2017 Jul; 180(?):23-35. doi:
10.1016/j.lfs.2017.05.013. [PMID: 28501482] - Mingfang Li, Yuan Du, Long Wang, Lilong Jiang, Xiaodong Ma, Ping Zhou, Ping Li, Huijun Li. Efficient Discovery of Quality Control Markers for Gastrodia elata Tuber by Fingerprint-Efficacy Relationship Modelling.
Phytochemical analysis : PCA.
2017 Jul; 28(4):351-359. doi:
10.1002/pca.2682. [PMID: 28317245] - Ji Yeon Jang, Hong Kyu Lee, Hwan-Su Yoo, Yeon Hee Seong. Phytoceramide ameliorates ß-amyloid protein-induced memory impairment and neuronal death in mice.
Archives of pharmacal research.
2017 Jun; 40(6):760-771. doi:
10.1007/s12272-017-0893-2. [PMID: 28600733] - Li Li, Daohua Xu, Jiantao Lin, Dawei Zhang, Guanhai Wang, Ling Sui, Hongyan Ding, Jikun Du. Coenzyme Q10 attenuated β-amyloid25-35-induced inflammatory responses in PC12 cells through regulation of the NF-κB signaling pathway.
Brain research bulletin.
2017 May; 131(?):192-198. doi:
10.1016/j.brainresbull.2017.04.014. [PMID: 28458038] - Vagif Soultanov, Julia Fedotova, Tamara Nikitina, Victor Roschin, Natalia Ordyan, Lucian Hritcu. Antidepressant-Like Effect of Ropren® in β-Amyloid-(25-35) Rat Model of Alzheimer's Disease with Altered Levels of Androgens.
Molecular neurobiology.
2017 05; 54(4):2611-2621. doi:
10.1007/s12035-016-9848-8. [PMID: 26993300] - Rong Yang, Li Wei, Qing-Qing Fu, Hua You, Hua-Rong Yu. SOD3 Ameliorates Aβ25-35-Induced Oxidative Damage in SH-SY5Y Cells by Inhibiting the Mitochondrial Pathway.
Cellular and molecular neurobiology.
2017 Apr; 37(3):513-525. doi:
10.1007/s10571-016-0390-z. [PMID: 27272114] - Xiuling Wang, Hong Zhang, Jian Liu, Rong Chen, Yong Tang, Haixia Chen, Li Gu, Mao Li, Shousong Cao, Dalian Qin, Jianming Wu. Inhibitory Effect of Lychee Seed Saponins on Apoptosis Induced by Aβ25-35 through Regulation of the Apoptotic and NF-κB Pathways in PC12 Cells.
Nutrients.
2017 Mar; 9(4):. doi:
10.3390/nu9040337. [PMID: 28353652] - Xiuling Wang, Jianming Wu, Chonglin Yu, Yong Tang, Jian Liu, Haixia Chen, Bingjin Jin, Qibing Mei, Shousong Cao, Dalian Qin. Lychee Seed Saponins Improve Cognitive Function and Prevent Neuronal Injury via Inhibiting Neuronal Apoptosis in a Rat Model of Alzheimer's Disease.
Nutrients.
2017 Feb; 9(2):. doi:
10.3390/nu9020105. [PMID: 28165366] - Yao Du, Hong Zheng, Huanhuan Xia, Liangcai Zhao, Wenyi Hu, Guanghui Bai, Zhihan Yan, Hongchang Gao. Early Effect of Amyloid β-Peptide on Hippocampal and Serum Metabolism in Rats Studied by an Integrated Method of NMR-Based Metabolomics and ANOVA-Simultaneous Component Analysis.
BioMed research international.
2017; 2017(?):3262495. doi:
10.1155/2017/3262495. [PMID: 28243597] - Rosario Randino, Manuela Grimaldi, Marco Persico, Augusta De Santis, Elena Cini, Walter Cabri, Antonella Riva, Gerardino D'Errico, Caterina Fattorusso, Anna Maria D'Ursi, Manuela Rodriquez. Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids.
Scientific reports.
2016 12; 6(?):38846. doi:
10.1038/srep38846. [PMID: 28004737] - Xiao G Wu, Shu S Wang, Hong Miao, Jian J Cheng, Shu F Zhang, Ya Z Shang. Scutellaria barbata flavonoids alleviate memory deficits and neuronal injuries induced by composited Aβ in rats.
Behavioral and brain functions : BBF.
2016 Dec; 12(1):33. doi:
10.1186/s12993-016-0118-8. [PMID: 27931218] - Amy K Smith, Christopher Lockhart, Dmitri K Klimov. Does Replica Exchange with Solute Tempering Efficiently Sample Aβ Peptide Conformational Ensembles?.
Journal of chemical theory and computation.
2016 Oct; 12(10):5201-5214. doi:
10.1021/acs.jctc.6b00660. [PMID: 27560127] - Trinidad Cruz-González, Estephania Cortez-Torres, Francisca Perez-Severiano, Blanca Espinosa, Jorge Guevara, Aarón Perez-Benitez, Francisco J Melendez, Alfonso Díaz, Ramsés E Ramírez. Antioxidative stress effect of epicatechin and catechin induced by Aβ25-35 in rats and use of the electrostatic potential and the Fukui function as a tool to elucidate specific sites of interaction.
Neuropeptides.
2016 Oct; 59(?):89-95. doi:
10.1016/j.npep.2016.04.001. [PMID: 27118677] - Julia Fedotova, Vagif Soultanov, Tamara Nikitina, Victor Roschin, Natalia Ordyan, Lucian Hritcu. Ropren® treatment reverses anxiety-like behavior and monoamines levels in gonadectomized rat model of Alzheimer's disease.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2016 Oct; 83(?):1444-1455. doi:
10.1016/j.biopha.2016.08.065. [PMID: 27599376] - Jiufang Yang, Xuanjun Liu, Xiaoxu Zhang, Qing Jin, Jingming Li. Phenolic Profiles, Antioxidant Activities, and Neuroprotective Properties of Mulberry (Morus atropurpurea Roxb.) Fruit Extracts from Different Ripening Stages.
Journal of food science.
2016 Oct; 81(10):C2439-C2446. doi:
10.1111/1750-3841.13426. [PMID: 27588828] - Yumin Wang, Yingchun Miao, Aamina Zia Mir, Long Cheng, Lina Wang, Linan Zhao, Qifu Cui, Weili Zhao, Hongquan Wang. Inhibition of beta-amyloid-induced neurotoxicity by pinocembrin through Nrf2/HO-1 pathway in SH-SY5Y cells.
Journal of the neurological sciences.
2016 Sep; 368(?):223-30. doi:
10.1016/j.jns.2016.07.010. [PMID: 27538638] - Nan Song, Ling Zhang, Wei Chen, Hua Zhu, Wei Deng, Yunlin Han, Jianguo Guo, Chuan Qin. Cyanidin 3-O-β-glucopyranoside activates peroxisome proliferator-activated receptor-γ and alleviates cognitive impairment in the APP(swe)/PS1(ΔE9) mouse model.
Biochimica et biophysica acta.
2016 09; 1862(9):1786-800. doi:
10.1016/j.bbadis.2016.05.016. [PMID: 27240542] - Guo-Qing Ouyang, Chuang-Jun Li, Jing-Zhi Yang, Li Li, Xiu-Yun Song, Yi-Na Jiang, Nai-Hong Chen, Jie Ma, Dong-Ming Zhang. Bioactive Coumarins from the Stems of Clausena emarginata.
Chemistry & biodiversity.
2016 Sep; 13(9):1178-1185. doi:
10.1002/cbdv.201500519. [PMID: 27450780] - Yinjie Li, Jikai Xu, Pu Xu, Shijie Song, Peng Liu, Tianyan Chi, Xuefei Ji, Ge Jin, Shimeng Qiu, Yapeng Hou, Chen Zheng, Lili Wang, Dali Meng, Libo Zou. Xanthoceras sorbifolia extracts ameliorate dendritic spine deficiency and cognitive decline via upregulation of BDNF expression in a rat model of Alzheimer's disease.
Neuroscience letters.
2016 08; 629(?):208-214. doi:
10.1016/j.neulet.2016.07.011. [PMID: 27412235] - Aishwarya Vedagiri, Sumathi Thangarajan. Mitigating effect of chrysin loaded solid lipid nanoparticles against Amyloid β25-35 induced oxidative stress in rat hippocampal region: An efficient formulation approach for Alzheimer's disease.
Neuropeptides.
2016 Aug; 58(?):111-25. doi:
10.1016/j.npep.2016.03.002. [PMID: 27021394] - Yue-Wei Ge, Chihiro Tohda, Shu Zhu, Yu-Min He, Kayo Yoshimatsu, Katsuko Komatsu. Effects of Oleanane-Type Triterpene Saponins from the Leaves of Eleutherococcus senticosus in an Axonal Outgrowth Assay.
Journal of natural products.
2016 07; 79(7):1834-41. doi:
10.1021/acs.jnatprod.6b00329. [PMID: 27400231] - Guang-Lei Ma, Juan Xiong, Guo-Xun Yang, Li-Long Pan, Chang-Ling Hu, Wei Wang, Hui Fan, Qiu-Hua Zhao, Hai-Yan Zhang, Jin-Feng Hu. Biginkgosides A-I, Unexpected Minor Dimeric Flavonol Diglycosidic Truxinate and Truxillate Esters from Ginkgo biloba Leaves and Their Antineuroinflammatory and Neuroprotective Activities.
Journal of natural products.
2016 05; 79(5):1354-64. doi:
10.1021/acs.jnatprod.6b00061. [PMID: 27140807] - Andreia Cuco, Ana Paula Serro, José Paulo Farinha, Benilde Saramago, Amélia Gonçalves da Silva. Interaction of the Alzheimer Aβ(25-35) peptide segment with model membranes.
Colloids and surfaces. B, Biointerfaces.
2016 May; 141(?):10-18. doi:
10.1016/j.colsurfb.2016.01.015. [PMID: 26816349] - Jennifer Tang, Richard J Alsop, Matilda Backholm, Hannah Dies, An-Chang Shi, Maikel C Rheinstädter. Amyloid-β(25-35) peptides aggregate into cross-β sheets in unsaturated anionic lipid membranes at high peptide concentrations.
Soft matter.
2016 Apr; 12(13):3165-76. doi:
10.1039/c5sm02619a. [PMID: 26934592] - Juan Zou, Pei-Shan Cai, Chao-Mei Xiong, Jin-Lan Ruan. Neuroprotective effect of peptides extracted from walnut (Juglans Sigilata Dode) proteins on Aβ25-35-induced memory impairment in mice.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.
2016 Feb; 36(1):21-30. doi:
10.1007/s11596-016-1536-4. [PMID: 26838735] - Robert Jesky, Hailong Chen. The neuritogenic and neuroprotective potential of senegenin against Aβ-induced neurotoxicity in PC 12 cells.
BMC complementary and alternative medicine.
2016 Jan; 16(?):26. doi:
10.1186/s12906-016-1006-3. [PMID: 26803813] - Pengjuan Xu, Hui Wang, Zhigui Li, Zhuo Yang. Triptolide attenuated injury via inhibiting oxidative stress in Amyloid-Beta25-35-treated differentiated PC12 cells.
Life sciences.
2016 Jan; 145(?):19-26. doi:
10.1016/j.lfs.2015.12.018. [PMID: 26679104] - Tangui Maurice, Manon Strehaiano, Nathalie Siméon, Christelle Bertrand, Arnaud Chatonnet. Learning performances and vulnerability to amyloid toxicity in the butyrylcholinesterase knockout mouse.
Behavioural brain research.
2016 Jan; 296(?):351-360. doi:
10.1016/j.bbr.2015.08.026. [PMID: 26306824] - Yu-Lian Zhang, Zhen Zhou, Wen-Wen Han, Lin-Lin Zhang, Wan-Shan Song, Jian-Hua Huang, Shuang Liu. Oleanolic Acid Inhibiting the Differentiation of Neural Stem Cells into Astrocyte by Down-Regulating JAK/STAT Signaling Pathway.
The American journal of Chinese medicine.
2016; 44(1):103-17. doi:
10.1142/s0192415x16500075. [PMID: 26916917] - Weiguo Dong, Feng Wang, Wanqing Guo, Xuehua Zheng, Yue Chen, Wenguang Zhang, Hong Shi. Aβ25-35 Suppresses Mitochondrial Biogenesis in Primary Hippocampal Neurons.
Cellular and molecular neurobiology.
2016 Jan; 36(1):83-91. doi:
10.1007/s10571-015-0222-6. [PMID: 26055049] - Camila Carla Guimarães, Denise Dias Oliveira, Mayara Valdevite, Ana Lúcia Fachin Saltoratto, Sarazete Izidia Vaz Pereira, Suzelei de Castro França, Ana Maria Soares Pereira, Paulo Sérgio Pereira. The glycosylated flavonoids vitexin, isovitexin, and quercetrin isolated from Serjania erecta Radlk (Sapindaceae) leaves protect PC12 cells against amyloid-β25-35 peptide-induced toxicity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2015 Dec; 86(?):88-94. doi:
10.1016/j.fct.2015.09.002. [PMID: 26385725] - De-Yang Shen, Thi Ngan Nguyen, Shwu-Jen Wu, Young-Ji Shiao, Hsin-Yi Hung, Ping-Chung Kuo, Daih-Huang Kuo, Tran Dinh Thang, Tian-Shung Wu. γ- and δ-Lactams from the Leaves of Clausena lansium.
Journal of natural products.
2015 Nov; 78(11):2521-30. doi:
10.1021/acs.jnatprod.5b00148. [PMID: 26523463] - Fei Li, Gang Wei, Ye Bai, Yunjun Li, Fengyuan Huang, Jian Lin, Qiuke Hou, Rudong Deng, Jian Hong Zhou, Sai Xia Zhang, Dong Feng Chen. MicroRNA-574 is involved in cognitive impairment in 5-month-old APP/PS1 mice through regulation of neuritin.
Brain research.
2015 Nov; 1627(?):177-88. doi:
10.1016/j.brainres.2015.09.022. [PMID: 26423933] - Gaëlle Naert, Valentine Ferré, Johann Meunier, Emeline Keller, Susanna Malmström, Laurent Givalois, François Carreaux, Jean-Pierre Bazureau, Tangui Maurice. Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25-35 peptide administration in mice.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2015 Nov; 25(11):2170-82. doi:
10.1016/j.euroneuro.2015.03.018. [PMID: 26381812] - Hyo Geun Kim, Gunhyuk Park, Soonmin Lim, Hanbyeol Park, Jin Gyu Choi, Hyun Uk Jeong, Min Seo Kang, Mi Kyeong Lee, Myung Sook Oh. Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3β pathway in vitro and in vivo.
Journal of ethnopharmacology.
2015 Aug; 171(?):196-204. doi:
10.1016/j.jep.2015.05.054. [PMID: 26068423] - Li Li, Jikun Du, Liyi Zou, Haishan Xia, Tie Wu, Yongho Kim, Yongwoo Lee. The Neuroprotective Effects of Decursin Isolated from Angelica gigas Nakai Against Amyloid β-Protein-Induced Apoptosis in PC 12 Cells via a Mitochondria-Related Caspase Pathway.
Neurochemical research.
2015 Aug; 40(8):1555-62. doi:
10.1007/s11064-015-1623-0. [PMID: 26077922] - Kenji Sasahara, Kenichi Morigaki, Yasuko Mori. Uptake of raft components into amyloid β-peptide aggregates and membrane damage.
Analytical biochemistry.
2015 Jul; 481(?):18-26. doi:
10.1016/j.ab.2015.04.014. [PMID: 25908557] - Beiru Zhang, Ping He, Yonghao Lu, Xiaohui Bian, Xu Yang, Xiaoying Fu, Yan Wu, Detian Li. HSF1 Relieves Amyloid-β-Induced Cardiomyocytes Apoptosis.
Cell biochemistry and biophysics.
2015 Jun; 72(2):579-87. doi:
10.1007/s12013-014-0505-4. [PMID: 25631374] - Dong Jia, Chunguang Rao, Shengxiang Xue, Jinli Lei. Purification, characterization and neuroprotective effects of a polysaccharide from Gynostemma pentaphyllum.
Carbohydrate polymers.
2015 May; 122(?):93-100. doi:
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