8-Br-cGMP (BioDeep_00000719669)
代谢物信息卡片
8-Br-cGMP(8-Bromo-cGMP)
化学式: C10H10BrN5NaO7P (444.93989000000005)
中文名称: 8-溴鸟苷3,5-环磷酸钠盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C2C(C(C(O2)N3C4=C(C(=O)NC(=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+]
InChI: /q
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mayumi Ikeda, Yu Ishima, Victor T G Chuang, Tsuyoshi Ikeda, Ryo Kinoshita, Hiroshi Watanabe, Tatsuhiro Ishida, Masaki Otagiri, Toru Maruyama. Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition.
Nitric oxide : biology and chemistry.
2017 Sep; 69(?):28-34. doi:
10.1016/j.niox.2017.04.005. [PMID: 28414103] - Julia Dolinina, Kristinn Sverrisson, Anna Rippe, Carl M Öberg, Bengt Rippe. Nitric oxide synthase inhibition causes acute increases in glomerular permeability in vivo, dependent upon reactive oxygen species.
American journal of physiology. Renal physiology.
2016 11; 311(5):F984-F990. doi:
10.1152/ajprenal.00152.2016. [PMID: 27681559] - Peng Zhang, Ai-Qin Mao, Chun-Yuan Sun, Xiao-Dong Zhang, Qiong-Xi Pan, Dan-Tong Yang, Jian Jin, Chun-Lei Tang, Zhen-Yu Yang, Xiao-Qiang Yao, Xiao-Jie Lu, Xin Ma. Translocation of PKG1α acts on TRPV4-C1 heteromeric channels to inhibit endothelial Ca(2+) entry.
Acta pharmacologica Sinica.
2016 Sep; 37(9):1199-207. doi:
10.1038/aps.2016.43. [PMID: 27397542] - Qi-Fei Gao, Li-Li Gu, Hui-Qin Wang, Cui-Fang Fei, Xiang Fang, Jamshaid Hussain, Shu-Jing Sun, Jing-Yun Dong, Hongtao Liu, Yong-Fei Wang. Cyclic nucleotide-gated channel 18 is an essential Ca2+ channel in pollen tube tips for pollen tube guidance to ovules in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America.
2016 Mar; 113(11):3096-101. doi:
10.1073/pnas.1524629113. [PMID: 26929345] - Zhenwei Shi, Feng Fu, Liming Yu, Wenjuan Xing, Feifei Su, Xiangyan Liang, Ru Tie, Lele Ji, Miaozhang Zhu, Jun Yu, Haifeng Zhang. Vasonatrin peptide attenuates myocardial ischemia-reperfusion injury in diabetic rats and underlying mechanisms.
American journal of physiology. Heart and circulatory physiology.
2015 Feb; 308(4):H281-90. doi:
10.1152/ajpheart.00666.2014. [PMID: 25485902] - Natalia Maria Ordoñez, Claudius Marondedze, Ludivine Thomas, Stefania Pasqualini, Lana Shabala, Sergey Shabala, Chris Gehring. Cyclic mononucleotides modulate potassium and calcium flux responses to H2O2 in Arabidopsis roots.
FEBS letters.
2014 Mar; 588(6):1008-15. doi:
10.1016/j.febslet.2014.01.062. [PMID: 24530500] - Jisheng Li, Honglei Jia, Jue Wang. cGMP and ethylene are involved in maintaining ion homeostasis under salt stress in Arabidopsis roots.
Plant cell reports.
2014 Mar; 33(3):447-59. doi:
10.1007/s00299-013-1545-8. [PMID: 24306353] - Yong-Fei Wang, Shintaro Munemasa, Noriyuki Nishimura, Hui-Min Ren, Nadia Robert, Michelle Han, Irina Puzõrjova, Hannes Kollist, Stephen Lee, Izumi Mori, Julian I Schroeder. Identification of cyclic GMP-activated nonselective Ca2+-permeable cation channels and associated CNGC5 and CNGC6 genes in Arabidopsis guard cells.
Plant physiology.
2013 Oct; 163(2):578-90. doi:
10.1104/pp.113.225045. [PMID: 24019428] - Małgorzata Pietrowska-Borek, Katarzyna Nuc. Both cyclic-AMP and cyclic-GMP can act as regulators of the phenylpropanoid pathway in Arabidopsis thaliana seedlings.
Plant physiology and biochemistry : PPB.
2013 Sep; 70(?):142-9. doi:
10.1016/j.plaphy.2013.05.029. [PMID: 23774376] - Zhijian Wang, Peng Yue, Dao-Hong Lin, Wen-Hui Wang. Carbon monoxide stimulates Ca2+ -dependent big-conductance K channels in the cortical collecting duct.
American journal of physiology. Renal physiology.
2013 Mar; 304(5):F543-52. doi:
10.1152/ajprenal.00530.2012. [PMID: 23235481] - Takahiro Joudoi, Yudai Shichiri, Nobuto Kamizono, Takaaki Akaike, Tomohiro Sawa, Jun Yoshitake, Naotaka Yamada, Sumio Iwai. Nitrated cyclic GMP modulates guard cell signaling in Arabidopsis.
The Plant cell.
2013 Feb; 25(2):558-71. doi:
10.1105/tpc.112.105049. [PMID: 23396828] - Mingzhu Wu, Fangquan Wang, Chen Zhang, Yanjie Xie, Bin Han, Jingjing Huang, Wenbiao Shen. Heme oxygenase-1 is involved in nitric oxide- and cGMP-induced α-Amy2/54 gene expression in GA-treated wheat aleurone layers.
Plant molecular biology.
2013 Jan; 81(1-2):27-40. doi:
10.1007/s11103-012-9979-x. [PMID: 23090695] - Yuan-Wei Zhang, Gary Rudnick. Myristoylation of cGMP-dependent protein kinase dictates isoform specificity for serotonin transporter regulation.
The Journal of biological chemistry.
2011 Jan; 286(4):2461-8. doi:
10.1074/jbc.m110.203935. [PMID: 21097501] - Michelle Boone, Marleen Kortenoeven, Joris H Robben, Peter M T Deen. Effect of the cGMP pathway on AQP2 expression and translocation: potential implications for nephrogenic diabetes insipidus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2010 Jan; 25(1):48-54. doi:
10.1093/ndt/gfp409. [PMID: 19666909] - Birgit Nimmervoll, Nina Svoboda, Beata Sacha, Hubert H Kerschbaum. Sustained elevation of cyclic guanosine monophosphate induces apoptosis in microglia.
Brain research bulletin.
2009 Dec; 80(6):428-32. doi:
10.1016/j.brainresbull.2009.08.002. [PMID: 19682559] - Yean Kyoung Koo, Jeong Mi Kim, Sun Young Kim, Ja Yong Koo, Doyeun Oh, Seonyang Park, Hye Sook Yun-Choi. Elevated plasma concentration of NO and cGMP may be responsible for the decreased platelet aggregation and platelet leukocyte conjugation in platelets hypo-responsive to catecholamines.
Platelets.
2009 Dec; 20(8):555-65. doi:
10.3109/09537100903337419. [PMID: 19874215] - Biguang Tuo, Guorong Wen, Yalin Zhang, Xuemei Liu, Xue Wang, Xiaoqiang Liu, Hui Dong. Involvement of phosphatidylinositol 3-kinase in cAMP- and cGMP-induced duodenal epithelial CFTR activation in mice.
American journal of physiology. Cell physiology.
2009 Sep; 297(3):C503-15. doi:
10.1152/ajpcell.00460.2008. [PMID: 19535511] - Jennifer A Steiner, Ana Marin D Carneiro, Jane Wright, Heinrich J G Matthies, Harish C Prasad, Christian K Nicki, Wolfgang R Dostmann, Carrie C Buchanan, Jackie D Corbin, Sharron H Francis, Randy D Blakely. cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.
Molecular brain.
2009 Aug; 2(?):26. doi:
10.1186/1756-6606-2-26. [PMID: 19656393] - Thejass Punathil, Santosh K Katiyar. Inhibition of non-small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2.
Molecular carcinogenesis.
2009 Mar; 48(3):232-242. doi:
10.1002/mc.20473. [PMID: 18680102] - Toshiaki Kume, Ryo Ito, Ryota Taguchi, Yasuhiko Izumi, Hiroshi Katsuki, Tetsuhiro Niidome, Yuki Takada-Takatori, Hachiro Sugimoto, Akinori Akaike. Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.
Journal of pharmacological sciences.
2009 Jan; 109(1):110-8. doi:
10.1254/jphs.08254fp. [PMID: 19122367] - Taiki Kida, Takahisa Murata, Masatoshi Hori, Hiroshi Ozaki. Chronic stimulation of farnesoid X receptor impairs nitric oxide sensitivity of vascular smooth muscle.
American journal of physiology. Heart and circulatory physiology.
2009 Jan; 296(1):H195-201. doi:
10.1152/ajpheart.00679.2008. [PMID: 19011043] - Christian Bopp, Stefan Hofer, Cornelius Busch, Fabian Spöhr, Markus A Weigand, Eike Martin, Alexandra Klein. Time-limited hyporesponsiveness to inhaled nitric oxide and pulmonary phosphodiesterase activity in endotoxemic rats.
The Journal of surgical research.
2008 Nov; 150(1):66-73. doi:
10.1016/j.jss.2008.01.009. [PMID: 18468638] - Theresa A John, Basil O Ibe, J Usha Raj. Regulation of endothelial nitric oxide synthase: involvement of protein kinase G 1 beta, serine 116 phosphorylation and lipid structures.
Clinical and experimental pharmacology & physiology.
2008 Feb; 35(2):148-58. doi:
10.1111/j.1440-1681.2007.04801.x. [PMID: 17892503] - Tobias Schulz, Udo Schumacher, Peter Prehm. Hyaluronan export by the ABC transporter MRP5 and its modulation by intracellular cGMP.
The Journal of biological chemistry.
2007 Jul; 282(29):20999-1004. doi:
10.1074/jbc.m700915200. [PMID: 17540771] - John J Peluso, Xiufang Liu, Jonathan Romak. Progesterone maintains basal intracellular adenosine triphosphate levels and viability of spontaneously immortalized granulosa cells by promoting an interaction between 14-3-3sigma and ATP synthase beta/precursor through a protein kinase G-dependent mechanism.
Endocrinology.
2007 May; 148(5):2037-44. doi:
10.1210/en.2006-1603. [PMID: 17303654] - Taro Kuwai, Junichi Hayashi. Nitric oxide pathway activation and impaired red blood cell deformability with hypercholesterolemia.
Journal of atherosclerosis and thrombosis.
2006 Dec; 13(6):286-94. doi:
10.5551/jat.13.286. [PMID: 17192693] - Y S Prakash, Adeyemi Iyanoye, Binnaz Ay, Gary C Sieck, Christina M Pabelick. Store-operated Ca2+ influx in airway smooth muscle: Interactions between volatile anesthetic and cyclic nucleotide effects.
Anesthesiology.
2006 Nov; 105(5):976-83. doi:
10.1097/00000542-200611000-00019. [PMID: 17065892] - Yih-Jer Wu, Mark Bond, Graciela B Sala-Newby, Andrew C Newby. Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation.
Circulation research.
2006 May; 98(9):1141-50. doi:
10.1161/01.res.0000219905.16312.28. [PMID: 16574903] - Nikolina Kutinová Canová, Dagmar Lincová, Eva Kmonícková, Ludmila Kameníková, Hassan Farghali. Nitric oxide production from rat adipocytes is modulated by beta3-adrenergic receptor agonists and is involved in a cyclic AMP-dependent lipolysis in adipocytes.
Nitric oxide : biology and chemistry.
2006 May; 14(3):200-11. doi:
10.1016/j.niox.2005.06.006. [PMID: 16413212] - Roman E Perri, Daniel A Langer, Suvro Chatterjee, Simon J Gibbons, Jay Gadgil, Sheng Cao, Gianrico Farrugia, Vijay H Shah. Defects in cGMP-PKG pathway contribute to impaired NO-dependent responses in hepatic stellate cells upon activation.
American journal of physiology. Gastrointestinal and liver physiology.
2006 Mar; 290(3):G535-42. doi:
10.1152/ajpgi.00297.2005. [PMID: 16269521] - Sandhya Sanghi, Rajesh Kumar, Manuela Smith, Kenneth M Baker, David E Dostal. Activation of protein kinase A by atrial natriuretic peptide in neonatal rat cardiac fibroblasts: role in regulation of the local renin-angiotensin system.
Regulatory peptides.
2005 Dec; 132(1-3):1-8. doi:
10.1016/j.regpep.2005.06.007. [PMID: 16194576] - A Elizabeth Linder, Lynnette P McCluskey, Kenneth R Cole, Katherine M Lanning, R Clinton Webb. Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta.
The Journal of pharmacology and experimental therapeutics.
2005 Jul; 314(1):9-15. doi:
10.1124/jpet.105.083634. [PMID: 15778264] - Seung-Soo Chung, Duck-Sun Ahn, Hong-Ghi Lee, Young-Ho Lee, Taick-Sang Nam. Inhibition of carbachol-evoked oscillatory currents by the NO donor sodium nitroprusside in guinea-pig ileal myocytes.
Experimental physiology.
2005 Jul; 90(4):577-86. doi:
10.1113/expphysiol.2004.029611. [PMID: 15833757] - Muriel André, Hélia Latado, Emanuela Felley-Bosco. Inducible nitric oxide synthase-dependent stimulation of PKGI and phosphorylation of VASP in human embryonic kidney cells.
Biochemical pharmacology.
2005 Feb; 69(4):595-602. doi:
10.1016/j.bcp.2004.11.007. [PMID: 15670578] - Lihua Chen, Günter Daum, Kanchan Chitaley, Scott A Coats, Daniel F Bowen-Pope, Martin Eigenthaler, Naresh R Thumati, Ulrich Walter, Alexander W Clowes. Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology.
2004 Aug; 24(8):1403-8. doi:
10.1161/01.atv.0000134705.39654.53. [PMID: 15178555] - Andrea Brand, John M Hawdon. Phosphoinositide-3-OH-kinase inhibitor LY294002 prevents activation of Ancylostoma caninum and Ancylostoma ceylanicum third-stage infective larvae.
International journal for parasitology.
2004 Jul; 34(8):909-14. doi:
10.1016/j.ijpara.2004.04.003. [PMID: 15217729] - Roberto Rodriguez, Bruno Molino, Harvey R Weiss, Peter M Scholz. Negative metabolic and coronary flow effects of decreases in cAMP and increases in cGMP in control and renal hypertensive rabbit hearts.
Journal of applied physiology (Bethesda, Md. : 1985).
2004 Jul; 97(1):439-45. doi:
10.1152/japplphysiol.01115.2003. [PMID: 14990553] - Xiao-Hong Jin, Helen E McGrath, John J Gildea, Helmy M Siragy, Robin A Felder, Robert M Carey. Renal interstitial guanosine cyclic 3', 5'-monophosphate mediates pressure-natriuresis via protein kinase G.
Hypertension (Dallas, Tex. : 1979).
2004 May; 43(5):1133-9. doi:
10.1161/01.hyp.0000123574.60586.7d. [PMID: 15007031] - Songcang Chen, James A McCormick, Kavitha Prabaker, Jian Wang, David Pearce, David G Gardner. Sgk1 mediates osmotic induction of NPR-A gene in rat inner medullary collecting duct cells.
Hypertension (Dallas, Tex. : 1979).
2004 Apr; 43(4):866-71. doi:
10.1161/01.hyp.0000121883.55722.45. [PMID: 15007040] - Shota Sasaki, Helmy M Siragy, John J Gildea, Robin A Felder, Robert M Carey. Production and role of extracellular guanosine cyclic 3', 5' monophosphate in sodium uptake in human proximal tubule cells.
Hypertension (Dallas, Tex. : 1979).
2004 Feb; 43(2):286-91. doi:
10.1161/01.hyp.0000112421.18551.1e. [PMID: 14718358] - Gursev S Dhaunsi, Pinar T Ozand. Nitric oxide promotes mitogen-induced dna synthesis in human dermal fibroblasts through cGMP.
Clinical and experimental pharmacology & physiology.
2004 Jan; 31(1-2):46-9. doi:
10.1111/j.1440-1681.2004.03948.x. [PMID: 14756683] - T D Hewitson, M Martic, I A Darby, K J Kelynack, T Bisucci, M G Tait, G J Becker. Intracellular cyclic nucleotide analogues inhibit in vitro mitogenesis and activation of fibroblasts derived from obstructed rat kidneys.
Nephron. Experimental nephrology.
2004; 96(2):e59-66. doi:
10.1159/000076405. [PMID: 14988593] - Joseph Zimpelmann, Ningjun Li, Kevin D Burns. Nitric oxide inhibits superoxide-stimulated urea permeability in the rat inner medullary collecting duct.
American journal of physiology. Renal physiology.
2003 Dec; 285(6):F1160-7. doi:
10.1152/ajprenal.00077.2003. [PMID: 12965888] - Mary Lee Terrell, Nilson Salas, V Bui, J Y Summy-Long, M Kadekaro. NO inhibition of the magnocellular neuroendocrine system in rats is independent of cGMP signaling pathway.
Experimental neurology.
2003 Dec; 184(2):846-56. doi:
10.1016/s0014-4886(03)00305-4. [PMID: 14769377] - G S Pullman, K Namjoshi, Y Zhang. Somatic embryogenesis in loblolly pine (Pinus taeda L.): improving culture initiation with abscisic acid and silver nitrate.
Plant cell reports.
2003 Sep; 22(2):85-95. doi:
10.1007/s00299-003-0673-y. [PMID: 12879261] - Charles Henry Cottart, Valérie Nivet-Antoine, Louis Do, Ghassan Al-Massarani, Geneviéve Descamps, François Xavier-Galen, Jean-Pierre Clot. Hepatic cytoprotection by nitric oxide and the cGMP pathway after ischaemia-reperfusion in the rat.
Nitric oxide : biology and chemistry.
2003 Sep; 9(2):57-63. doi:
10.1016/j.niox.2003.09.003. [PMID: 14623171] - John M Hawdon, Bennett Datu. The second messenger cyclic GMP mediates activation in Ancylostoma caninum infective larvae.
International journal for parasitology.
2003 Jul; 33(8):787-93. doi:
10.1016/s0020-7519(03)00088-2. [PMID: 12865078] - El-Sayed Akool, Hartmut Kleinert, Farid M A Hamada, Mohamed H Abdelwahab, Ulrich Förstermann, Josef Pfeilschifter, Wolfgang Eberhardt. Nitric oxide increases the decay of matrix metalloproteinase 9 mRNA by inhibiting the expression of mRNA-stabilizing factor HuR.
Molecular and cellular biology.
2003 Jul; 23(14):4901-16. doi:
10.1128/mcb.23.14.4901-4916.2003. [PMID: 12832476] - Ken'ichi Yamaguchi, Hitoshi Hama. A study on the mechanism by which sodium nitroprusside, a nitric oxide donor, applied to the anteroventral third ventricular region provokes facilitation of vasopressin secretion in conscious rats.
Brain research.
2003 Apr; 968(1):35-43. doi:
10.1016/s0006-8993(02)04246-4. [PMID: 12644262] - Yuan Wei, Wenhui Wang. Angiotensin II stimulates basolateral K channels in rat cortical collecting ducts.
American journal of physiology. Renal physiology.
2003 Jan; 284(1):F175-81. doi:
10.1152/ajprenal.00211.2002. [PMID: 12388389] - Michael J Ryan, Thomas A Black, Susan L Millard, Kenneth W Gross, George Hajduczok. Endothelin-1 increases calcium and attenuates renin gene expression in As4.1 cells.
American journal of physiology. Heart and circulatory physiology.
2002 Dec; 283(6):H2458-65. doi:
10.1152/ajpheart.00295.2002. [PMID: 12388321] - Anne K Green, Olga Zolle, Alec W M Simpson. Atrial natriuretic peptide attenuates Ca2+ oscillations and modulates plasma membrane Ca2+ fluxes in rat hepatocytes.
Gastroenterology.
2002 Oct; 123(4):1291-303. doi:
10.1053/gast.2002.35994. [PMID: 12360489] - Satoshi Komatsu, Koji Miyazaki, Richard A Tuft, Mitsuo Ikebe. Translocation of telokin by cGMP signaling in smooth muscle cells.
American journal of physiology. Cell physiology.
2002 Sep; 283(3):C752-61. doi:
10.1152/ajpcell.00501.2001. [PMID: 12176732] - Najma Begum, Oana A Sandu, Noreen Duddy. Negative regulation of rho signaling by insulin and its impact on actin cytoskeleton organization in vascular smooth muscle cells: role of nitric oxide and cyclic guanosine monophosphate signaling pathways.
Diabetes.
2002 Jul; 51(7):2256-63. doi:
10.2337/diabetes.51.7.2256. [PMID: 12086958] - Aleksandra Sindiće, Candan Başoglu, Ayhan Cerçi, Jochen R Hirsch, Regine Potthast, Michaela Kuhn, Yashoda Ghanekar, Sandhya S Visweswariah, Eberhard Schlatter. Guanylin, uroguanylin, and heat-stable euterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G protein in human proximal tubule cells.
The Journal of biological chemistry.
2002 May; 277(20):17758-64. doi:
10.1074/jbc.m110627200. [PMID: 11889121] - Hideki Tanioka, Koichi Nakamura, Shinsei Fujimura, Makoto Yoshida, Mizue Suzuki-Kusaba, Hiroaki Hisa, Susumu Satoh. Facilitatory role of NO in neural norepinephrine release in the rat kidney.
American journal of physiology. Regulatory, integrative and comparative physiology.
2002 May; 282(5):R1436-42. doi:
10.1152/ajpregu.00697.2001. [PMID: 11959687] - Aurélie-Anne Chausse, Valérie Nivet-Antoine, Chantal Martin, Jean-Pierre Clot, François-Xavier Galen. Protective effect of nitric oxide on isolated rat hepatocytes submitted to an oxidative stress.
Metabolism: clinical and experimental.
2002 Feb; 51(2):175-9. doi:
10.1053/meta.2002.29983. [PMID: 11833044] - Sheng Nan Wu, Yuk Kang Lo, Chien Chich Chen, Hui Fang Li, Hung Ting Chiang. Inhibitory effect of the plant-extract osthole on L-type calcium current in NG108-15 neuronal cells.
Biochemical pharmacology.
2002 Jan; 63(2):199-206. doi:
10.1016/s0006-2952(01)00873-5. [PMID: 11841794] - Tobias Polte, Anke Hemmerle, Georg Berndt, Nina Grosser, Aida Abate, Henning Schröder. Atrial natriuretic peptide reduces cyclosporin toxicity in renal cells: role of cGMP and heme oxygenase-1.
Free radical biology & medicine.
2002 Jan; 32(1):56-63. doi:
10.1016/s0891-5849(01)00761-4. [PMID: 11755317] - T Riediger, H A Schmid, T Lutz, E Simon. Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP.
American journal of physiology. Regulatory, integrative and comparative physiology.
2001 Dec; 281(6):R1833-43. doi:
10.1152/ajpregu.2001.281.6.r1833. [PMID: 11705768] - D Bacic, N Hernando, M Traebert, E Lederer, H Völkl, J Biber, B Kaissling, H Murer. Regulation of the renal type IIa Na/Pi cotransporter by cGMP.
Pflugers Archiv : European journal of physiology.
2001 Nov; 443(2):306-13. doi:
10.1007/s004240100695. [PMID: 11713658] - G Pietig, T Mehrens, J R Hirsch, I Cetinkaya, H Piechota, E Schlatter. Properties and regulation of organic cation transport in freshly isolated human proximal tubules.
The Journal of biological chemistry.
2001 Sep; 276(36):33741-6. doi:
10.1074/jbc.m104617200. [PMID: 11447227] - S Hillinger, P Sandera, G L Carboni, U Stammberger, M Zalunardo, G Schoedon, R A Schmid. Survival and graft function in a large animal lung transplant model after 30 h preservation and substitution of the nitric oxide pathway.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
2001 Sep; 20(3):508-13. doi:
10.1016/s1010-7940(01)00820-x. [PMID: 11509271] - S Yamamoto, F Yan, H Zhou, H H Tai. Serine 331 is the major site of receptor phosphorylation induced by agents that activate protein kinase G in HEK 293 cells overexpressing thromboxane receptor alpha.
Archives of biochemistry and biophysics.
2001 Sep; 393(1):97-105. doi:
10.1006/abbi.2001.2505. [PMID: 11516166] - X H Jin, H M Siragy, R M Carey. Renal interstitial cGMP mediates natriuresis by direct tubule mechanism.
Hypertension (Dallas, Tex. : 1979).
2001 Sep; 38(3):309-16. doi:
10.1161/01.hyp.38.3.309. [PMID: 11566896] - S Kim, K Jee, D Kim, H Koh, J Chung. Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
The Journal of biological chemistry.
2001 Apr; 276(16):12864-70. doi:
10.1074/jbc.m001492200. [PMID: 11278269] - R R Fiscus, A W Tu, S B Chew. Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC12 cells.
Neuroreport.
2001 Feb; 12(2):185-9. doi:
10.1097/00001756-200102120-00003. [PMID: 11209918] - K N Patel, L Yan, A Gandhi, P M Scholz, H R Weiss. Interaction between the opposing functional effects of cyclic AMP and cyclic GMP in hypertrophic cardiac myocytes.
Basic research in cardiology.
2001 Feb; 96(1):34-41. doi:
10.1007/s003950170075. [PMID: 11215530] - A J Ingram, L James, L Cai, K Thai, H Ly, J W Scholey. NO inhibits stretch-induced MAPK activity by cytoskeletal disruption.
The Journal of biological chemistry.
2000 Dec; 275(51):40301-6. doi:
10.1074/jbc.m007018200. [PMID: 10984494] - D B Pearse, P M Becker. Effect of time and vascular pressure on permeability and cyclic nucleotides in ischemic lungs.
American journal of physiology. Heart and circulatory physiology.
2000 Nov; 279(5):H2077-84. doi:
10.1152/ajpheart.2000.279.5.h2077. [PMID: 11045940] - W H Wang. The cGMP-dependent protein kinase stimulates the basolateral 18-pS K channel of the rat CCD.
American journal of physiology. Cell physiology.
2000 Jun; 278(6):C1212-7. doi:
10.1152/ajpcell.2000.278.6.c1212. [PMID: 10837349] - J Sörensson, M Ohlson, A Björnson, B Haraldsson. Orosomucoid has a cAMP-dependent effect on human endothelial cells and inhibits the action of histamine.
American journal of physiology. Heart and circulatory physiology.
2000 May; 278(5):H1725-31. doi:
10.1152/ajpheart.2000.278.5.h1725. [PMID: 10775154] - P Sandera, S Hillinger, U Stammberger, G Schoedon, M Zalunardo, W Weder, R A Schmid. 8-Br-cyclic GMP given during reperfusion improves post-transplant lung edema and free radical injury.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
2000 Feb; 19(2):173-8. doi:
10.1016/s1053-2498(99)00129-1. [PMID: 10703694] - A Y Bagrov, R I Dmitrieva, N A Dorofeeva, O V Fedorova, D A Lopatin, E G Lakatta, M T Droy-Lefaix. Cicletanine reverses vasoconstriction induced by the endogenous sodium pump ligand, marinobufagenin, via a protein kinase C dependent mechanism.
Journal of hypertension.
2000 Feb; 18(2):209-15. doi:
10.1097/00004872-200018020-00012. [PMID: 10694190] - D P Healy, G Jayaraman, O Ashirova. Chemical hypoxia-induced increases in dopamine D1A receptor mRNA in renal epithelial cells are mediated by nitric oxide.
Acta physiologica Scandinavica.
2000 Jan; 168(1):233-8. doi:
10.1046/j.1365-201x.2000.00666.x. [PMID: 10691806] - H D Rupprecht, Y Akagi, A Keil, G Hofer. Nitric oxide inhibits growth of glomerular mesangial cells: role of the transcription factor EGR-1.
Kidney international.
2000 Jan; 57(1):70-82. doi:
10.1046/j.1523-1755.2000.00828.x. [PMID: 10620189] - G Basini, F Grasselli, N Ponderato, S Bussolati, C Tamanini. Lipid hydroperoxide and cGMP are not involved in nitric oxide inhibition of steroidogenesis in bovine granulosa cells.
Reproduction, fertility, and development.
2000; 12(5-6):289-95. doi:
10.1071/rd00089. [PMID: 11451020] - A M Hamad, S R Johnson, A J Knox. Antiproliferative effects of NO and ANP in cultured human airway smooth muscle.
The American journal of physiology.
1999 11; 277(5):L910-8. doi:
10.1152/ajplung.1999.277.5.l910. [PMID: 10564175] - C D Collard, A Agah, W Reenstra, J Buras, G L Stahl. Endothelial nuclear factor-kappaB translocation and vascular cell adhesion molecule-1 induction by complement: inhibition with anti-human C5 therapy or cGMP analogues.
Arteriosclerosis, thrombosis, and vascular biology.
1999 Nov; 19(11):2623-9. doi:
10.1161/01.atv.19.11.2623. [PMID: 10559004] - F X Galen, C H Cottart, E Souil, A T Dinh-Xuan, M Vaubourdolle, V Nivet, J P Clot. [Role of nitric oxide synthase III and guanosine 3':5'- cyclic monophosphate in the protection exerted by nitric oxide on hepatic ischemia-reperfusion injury].
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.
1999 Oct; 322(10):871-7. doi:
10.1016/s0764-4469(00)86653-6. [PMID: 10609091] - S Hillinger, R A Schmid, P Sandera, U Stammberger, D Schneiter, G Schoedon, W Weder. 8-Br-cGMP is superior to prostaglandin E1 for lung preservation.
The Annals of thoracic surgery.
1999 Oct; 68(4):1138-42; discussion 1143. doi:
10.1016/s0003-4975(99)00981-9. [PMID: 10543469] - J R Hirsch, G Weber, I Kleta, E Schlatter. A novel cGMP-regulated K+ channel in immortalized human kidney epitheliall cells (IHKE-1).
The Journal of physiology.
1999 Sep; 519 Pt 3(?):645-55. doi:
10.1111/j.1469-7793.1999.0645n.x. [PMID: 10457080] - I N Suwastika, C A Gehring. The plasma membrane H+-ATPase from Tradescantia stem and leaf tissue is modulated in vitro by cGMP.
Archives of biochemistry and biophysics.
1999 Jul; 367(1):137-9. doi:
10.1006/abbi.1999.1228. [PMID: 10375409] - D H Warden, A J Croatt, Z S Katusic, K A Nath. Characterization of acute reversible systemic hypertension in a model of heme protein-induced renal injury.
The American journal of physiology.
1999 07; 277(1):F58-65. doi:
10.1152/ajprenal.1999.277.1.f58. [PMID: 10409298] - P Sandner, M Kornfeld, X Ruan, W J Arendshorst, A Kurtz. Nitric oxide/cAMP interactions in the control of rat renal vascular resistance.
Circulation research.
1999 Feb; 84(2):186-92. doi:
10.1161/01.res.84.2.186. [PMID: 9933250] - N Kronemann, W A Nockher, R Busse, V B Schini-Kerth. Growth-inhibitory effect of cyclic GMP- and cyclic AMP-dependent vasodilators on rat vascular smooth muscle cells: effect on cell cycle and cyclin expression.
British journal of pharmacology.
1999 Jan; 126(1):349-57. doi:
10.1038/sj.bjp.0702305. [PMID: 10051155] - W Lenz, M Herten, R Gerzer, C Drummer. Regulation of natriuretic peptide (urodilatin) release in a human kidney cell line.
Kidney international.
1999 Jan; 55(1):91-9. doi:
10.1046/j.1523-1755.1999.00242.x. [PMID: 9893117] - J D Imig, E W Inscho, P C Deichmann, K M Reddy, J R Falck. Afferent arteriolar vasodilation to the sulfonimide analog of 11, 12-epoxyeicosatrienoic acid involves protein kinase A.
Hypertension (Dallas, Tex. : 1979).
1999 Jan; 33(1 Pt 2):408-13. doi:
10.1161/01.hyp.33.1.408. [PMID: 9931138] - J D Chiche, S M Schlutsmeyer, D B Bloch, S M de la Monte, J D Roberts, G Filippov, S P Janssens, A Rosenzweig, K D Bloch. Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP.
The Journal of biological chemistry.
1998 Dec; 273(51):34263-71. doi:
10.1074/jbc.273.51.34263. [PMID: 9852090] - A Alioua, Y Tanaka, M Wallner, F Hofmann, P Ruth, P Meera, L Toro. The large conductance, voltage-dependent, and calcium-sensitive K+ channel, Hslo, is a target of cGMP-dependent protein kinase phosphorylation in vivo.
The Journal of biological chemistry.
1998 Dec; 273(49):32950-6. doi:
10.1074/jbc.273.49.32950. [PMID: 9830046] - M Kubokawa, S Nakaya, Y Yoshioka, K Nakamura, F Sato, Y Mori, T Kubota. Activation of inwardly rectifying K+ channel in OK proximal tubule cells involves cGMP-dependent phosphorylation process.
The Japanese journal of physiology.
1998 Dec; 48(6):467-76. doi:
10.2170/jjphysiol.48.467. [PMID: 10021500] - T Maeda, N Murase, V Subbotin, T Sakamoto, T Yamada, M Terakura, S Todo. Analogs of cyclic nucleotides in rat liver preservation.
Transplantation.
1998 Oct; 66(7):844-51. doi:
10.1097/00007890-199810150-00006. [PMID: 9798692] - C Wagner, A Pfeifer, P Ruth, F Hofmann, A Kurtz. Role of cGMP-kinase II in the control of renin secretion and renin expression.
The Journal of clinical investigation.
1998 Oct; 102(8):1576-82. doi:
10.1172/jci4044. [PMID: 9788971] - L X Cao, E Shen. Intracerebroventricularly injected L-arginine-induced vasopressin release is mediated by cGMP in rats.
Zhongguo yao li xue bao = Acta pharmacologica Sinica.
1998 Sep; 19(5):459-62. doi:
NULL. [PMID: 10375810] - M Lu, W H Wang. Reaction of nitric oxide with superoxide inhibits basolateral K+ channels in the rat CCD.
The American journal of physiology.
1998 07; 275(1):C309-16. doi:
10.1152/ajpcell.1998.275.1.c309. [PMID: 9688863] - J Bełtowski, D Górny, A Marciniak. The mechanism of Na+, K+-ATPase inhibition by atrial natriuretic factor in rat renal medulla.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
1998 Jun; 49(2):271-83. doi:
. [PMID: 9670110] - A Kurtz, K H Götz, M Hamann, M Kieninger, C Wagner. Stimulation of renin secretion by NO donors is related to the cAMP pathway.
The American journal of physiology.
1998 04; 274(4):F709-17. doi:
10.1152/ajprenal.1998.274.4.f709. [PMID: 9575895] - J Yao, H O Schoecklmann, F Pröls, S Gauer, R B Sterzel. Exogenous nitric oxide inhibits mesangial cell adhesion to extracellular matrix components.
Kidney international.
1998 Mar; 53(3):598-608. doi:
10.1046/j.1523-1755.1998.00793.x. [PMID: 9507204] - J H Guh, T L Hwang, F N Ko, S C Chueh, M K Lai, C M Teng. Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor.
Molecular pharmacology.
1998 Mar; 53(3):467-74. doi:
10.1124/mol.53.3.467. [PMID: 9495813]
