sodium tungstate (BioDeep_00000718433)
代谢物信息卡片
sodium tungstate
化学式: Na2O4W (293.91015300000004)
中文名称: 鎢酸鈉
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: [O-][W](=O)(=O)[O-].[Na+].[Na+]
InChI: 2*-1
相关代谢途径
Reactome(0)
BioCyc(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- . Toxicology and carcinogenesis studies of sodium tungstate dihydrate in Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice (drinking water studies).
National Toxicology Program technical report series.
2021 Nov; ?(599):. doi:
10.22427/ntp-tr-599. [PMID: 35072664] - Fatma Aridhi, Hajer Sghaier, Allyzée Gaitanaros, Ayda Khadri, Samira Aschi-Smiti, Renaud Brouquisse. Nitric oxide production is involved in maintaining energy state in Alfalfa (Medicago sativa L.) nodulated roots under both salinity and flooding.
Planta.
2020 Jul; 252(2):22. doi:
10.1007/s00425-020-03422-1. [PMID: 32676756] - Ghazale Cheraghi, Elnaz Hajiabedi, Behnaz Niaghi, Firouzeh Nazari, Parvaneh Naserzadeh, Mir-Jamal Hosseini. High doses of sodium tungstate can promote mitochondrial dysfunction and oxidative stress in isolated mitochondria.
Journal of biochemical and molecular toxicology.
2019 Apr; 33(4):e22266. doi:
10.1002/jbt.22266. [PMID: 30597718] - Kun Yan, Tiantian Bian, Wenjun He, Guangxuan Han, Mengxue Lv, Mingzhu Guo, Ming Lu. Root Abscisic Acid Contributes to Defending Photoinibition in Jerusalem Artichoke (Helianthus tuberosus L.) under Salt Stress.
International journal of molecular sciences.
2018 Dec; 19(12):. doi:
10.3390/ijms19123934. [PMID: 30544576] - Hyun Jin Lee, Horacio A Peredo, Silvana M Cantú, Adriana S Donoso, Ana M Puyó, Marcelo R Choi. Effects of sodium tungstate and vanadyl sulphate on the liberation of prostanoids of the mesenteric vascular bed in diabetic rats.
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis.
2018 Nov; 30(6):249-257. doi:
10.1016/j.arteri.2018.04.001. [PMID: 29887329] - Romina Bertinat, Francisco Westermeier, Pamela Silva, Rodrigo Gatica, Joana Moitinho Oliveira, Francisco Nualart, Ramón Gomis, Alejandro J Yáñez. The Antidiabetic Agent Sodium Tungstate Induces Abnormal Glycogen Accumulation in Renal Proximal Tubules from Diabetic IRS2-Knockout Mice.
Journal of diabetes research.
2018; 2018(?):5697970. doi:
10.1155/2018/5697970. [PMID: 30003110] - Pinke Patel, Guruprasad Kadur Narayanaswamy, Sunita Kataria, Lokesh Baghel. Involvement of nitric oxide in enhanced germination and seedling growth of magnetoprimed maize seeds.
Plant signaling & behavior.
2017 12; 12(12):e1293217. doi:
10.1080/15592324.2017.1293217. [PMID: 28277969] - Romina Bertinat, Francisco Westermeier, Pamela Silva, Jie Shi, Francisco Nualart, Xuhang Li, Alejandro J Yáñez. Anti-Diabetic Agent Sodium Tungstate Induces the Secretion of Pro- and Anti-Inflammatory Cytokines by Human Kidney Cells.
Journal of cellular physiology.
2017 Feb; 232(2):355-362. doi:
10.1002/jcp.25429. [PMID: 27186953] - Rachel P Frawley, Matthew J Smith, Kimber L White, Susan A Elmore, Ron Herbert, Rebecca Moore, Lauren M Staska, Mamta Behl, Michelle J Hooth, Grace E Kissling, Dori R Germolec. Immunotoxic effects of sodium tungstate dihydrate on female B6C3F1/N mice when administered in drinking water.
Journal of immunotoxicology.
2016 09; 13(5):666-75. doi:
10.3109/1547691x.2016.1154118. [PMID: 27223060] - Yu V Karpets, Yu E Kolupaev, T O Yastreb. SIGNAL MEDIATORS AT INDUCTION OF HEAT RESISTANCE OF WHEAT PLANTLETS BY SHORT-TERM HEATING.
Ukrainian biochemical journal.
2015 Nov; 87(6):104-12. doi:
10.15407/ubj87.06.104. [PMID: 27025064] - Romina Bertinat, Pamela Silva, Elizabeth Mann, Xuhang Li, Francisco Nualart, Alejandro J Yáñez. In vivo sodium tungstate treatment prevents E-cadherin loss induced by diabetic serum in HK-2 cell line.
Journal of cellular physiology.
2015 Oct; 230(10):2437-46. doi:
10.1002/jcp.24974. [PMID: 25728412] - Wilfred C McCain, Lee C B Crouse, Mathew A Bazar, Laurie E Roszell, Glenn J Leach, John R Middleton, Gunda Reddy. Subchronic Oral Toxicity of Sodium Tungstate in Sprague-Dawley Rats.
International journal of toxicology.
2015 Jul; 34(4):336-45. doi:
10.1177/1091581815585568. [PMID: 26023051] - Ioannis Dimosthenis S Adamakis, Emmanuel Panteris, Eleftherios P Eleftheriou. 'CLASPing' tungsten's effects on microtubules with 'PINs'.
Plant signaling & behavior.
2015; 10(10):e1064572. doi:
10.1080/15592324.2015.1064572. [PMID: 26313814] - Rigoberto Medina-Andrés, Alejandro Solano-Peralta, Juan Pablo Saucedo-Vázquez, Selene Napsucialy-Mendivil, Jaime Arturo Pimentel-Cabrera, Martha Elena Sosa-Torres, Joseph G Dubrovsky, Verónica Lira-Ruan. The nitric oxide production in the moss Physcomitrella patens is mediated by nitrate reductase.
PloS one.
2015; 10(3):e0119400. doi:
10.1371/journal.pone.0119400. [PMID: 25742644] - Alicia M Bolt, Valérie Sabourin, Manuel Flores Molina, Alice M Police, Luis Fernando Negro Silva, Dany Plourde, Maryse Lemaire, Josie Ursini-Siegel, Koren K Mann. Tungsten targets the tumor microenvironment to enhance breast cancer metastasis.
Toxicological sciences : an official journal of the Society of Toxicology.
2015 Jan; 143(1):165-77. doi:
10.1093/toxsci/kfu219. [PMID: 25324207] - Maryam Abooali, Gurprit S Lall, Karen Coughlan, Harjinder S Lall, Bernhard F Gibbs, Vadim V Sumbayev. Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function.
Scientific reports.
2014 Sep; 4(?):6307. doi:
10.1038/srep06307. [PMID: 25200751] - Sherry Sachdeva, Pramod Kushwaha, S J S Flora. Effects of sodium tungstate on oxidative stress enzymes in rats.
Toxicology mechanisms and methods.
2013 Sep; 23(7):519-27. doi:
10.3109/15376516.2013.787132. [PMID: 23496299] - Lian Xu, Kashif Rafiq Zahid, Liangrong He, Wenwen Zhang, Xin He, Xianlong Zhang, Xiyan Yang, Longfu Zhu. GhCAX3 gene, a novel Ca(2+)/H(+) exchanger from cotton, confers regulation of cold response and ABA induced signal transduction.
PloS one.
2013; 8(6):e66303. doi:
10.1371/journal.pone.0066303. [PMID: 23776653] - Mustafa Aydemir, Nihal Ozturk, Serdar Dogan, Mutay Aslan, Yusuf Olgar, Semir Ozdemir. Sodium tungstate administration ameliorated diabetes-induced electrical and contractile remodeling of rat heart without normalization of hyperglycemia.
Biological trace element research.
2012 Aug; 148(2):216-23. doi:
10.1007/s12011-012-9350-8. [PMID: 22351103] - Yi Hsuan Chen, Ching Huei Kao. Calcium is involved in nitric oxide- and auxin-induced lateral root formation in rice.
Protoplasma.
2012 Jan; 249(1):187-95. doi:
10.1007/s00709-011-0277-2. [PMID: 21491156] - A K Glian'ko, N B Mitanova, A V Stepanov. [Influence of environmental factors on the generation of nitric oxide in the roots of etiolated pea seedlings].
Prikladnaia biokhimiia i mikrobiologiia.
2012 Jan; 48(1):95-102. doi:
". [PMID: 22567891] - Josie E Bamford, Alicia D Butler, Katherine E Heim, Charles A Pittinger, Ranulfo Lemus, Jane P Staveley, K Brian Lee, Carmen Venezia, Michael J Pardus. Toxicity of sodium tungstate to earthworm, oat, radish, and lettuce.
Environmental toxicology and chemistry.
2011 Oct; 30(10):2312-8. doi:
10.1002/etc.635. [PMID: 21805499] - M Milagros Gómez-Gómez, Nuria Rodríguez-Fariñas, Benito Cañas-Montalvo, Jorge Domínguez, Joan Guinovart, Carmen Cámara-Rica. Biospeciation of tungsten in the serum of diabetic and healthy rats treated with the antidiabetic agent sodium tungstate.
Talanta.
2011 May; 84(4):1011-8. doi:
10.1016/j.talanta.2011.02.050. [PMID: 21530773] - Gustavo S Guandalini, Lingsu Zhang, Elisa Fornero, Jose A Centeno, Vishwesh P Mokashi, Pedro A Ortiz, Michael D Stockelman, Andrew R Osterburg, Gail G Chapman. Tissue distribution of tungsten in mice following oral exposure to sodium tungstate.
Chemical research in toxicology.
2011 Apr; 24(4):488-93. doi:
10.1021/tx200011k. [PMID: 21375269] - José Ángel Martín-Rodríguez, Rafael León-Morcillo, Horst Vierheilig, Juan Antonio Ocampo, Jutta Ludwig-Müller, José Manuel García-Garrido. Ethylene-dependent/ethylene-independent ABA regulation of tomato plants colonized by arbuscular mycorrhiza fungi.
The New phytologist.
2011 Apr; 190(1):193-205. doi:
10.1111/j.1469-8137.2010.03610.x. [PMID: 21232061] - M Amigó-Correig, S Barceló-Batllori, S Piquer, M Soty, G Pujadas, R Gasa, A Bortolozzi, M C Carmona, R Gomis. Sodium tungstate regulates food intake and body weight through activation of the hypothalamic leptin pathway.
Diabetes, obesity & metabolism.
2011 Mar; 13(3):235-42. doi:
10.1111/j.1463-1326.2010.01339.x. [PMID: 21205112] - José Angel Martín Rodriguez, Rafael León Morcillo, Horst Vierheilig, Juan Antonio Ocampo, Jutta Ludwig-Müller, José Manuel García Garrido. Mycorrhization of the notabilis and sitiens tomato mutants in relation to abscisic acid and ethylene contents.
Journal of plant physiology.
2010 May; 167(8):606-13. doi:
10.1016/j.jplph.2009.11.014. [PMID: 20079554] - Pheona M Radcliffe, Teresa L Leavens, Dean J Wagner, Ayodele O Olabisi, Melanie F Struve, Brian A Wong, Earl Tewksbury, Gail D Chapman, David C Dorman. Pharmacokinetics of radiolabeled tungsten ((188)W) in male Sprague-Dawley rats following acute sodium tungstate inhalation.
Inhalation toxicology.
2010 Jan; 22(1):69-76. doi:
10.3109/08958370902913237. [PMID: 20017594] - Jordi Altirriba, Albert Barbera, Héctor Del Zotto, Belen Nadal, Sandra Piquer, Alex Sánchez-Pla, Juan J Gagliardino, Ramon Gomis. Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach.
BMC genomics.
2009 Aug; 10(?):406. doi:
10.1186/1471-2164-10-406. [PMID: 19715561] - Nupur Srivastava, Vijay K Gonugunta, Mallikarjuna R Puli, Agepati S Raghavendra. Nitric oxide production occurs downstream of reactive oxygen species in guard cells during stomatal closure induced by chitosan in abaxial epidermis of Pisum sativum.
Planta.
2009 Mar; 229(4):757-65. doi:
10.1007/s00425-008-0855-5. [PMID: 19084995] - Zahra Heidari, Mehdi Harati, Hamid Reza Mahmoudzadeh-Sagheb, Bita Moudi. Beta cell protective effects of sodium tungstate in streptozotocin-induced diabetic rats: glycemic control, blockage of oxidative stress and beta cell histochemistry.
Iranian biomedical journal.
2008 07; 12(3):143-52. doi:
NULL. [PMID: 18762817] - J Ballester, M C Muñoz, J Domínguez, M J Palomo, M Rivera, T Rigau, J J Guinovart, J E Rodríguez-Gil. Tungstate administration improves the sexual and reproductive function in female rats with streptozotocin-induced diabetes.
Human reproduction (Oxford, England).
2007 Aug; 22(8):2128-35. doi:
10.1093/humrep/dem168. [PMID: 17588954] - Snezana Uskoković-Marković, Marina Milenković, Aleksandra Topić, Jelena Kotur-Stevuljević, Aleksandra Stefanović, Jelena Antić-Stanković. Protective effects of tungstophosphoric acid and sodium tungstate on chemically induced liver necrosis in wistar rats.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2007; 10(3):340-9. doi:
NULL. [PMID: 17727797] - Joan Ballester, Jorge Domínguez, M Carmen Muñoz, Meritxell Sensat, Teresa Rigau, Joan J Guinovart, Joan E Rodríguez-Gil. Tungstate treatment improves Leydig cell function in streptozotocin-diabetic rats.
Journal of andrology.
2005 Nov; 26(6):706-15. doi:
10.2164/jandrol.04156. [PMID: 16291965] - Atsunori Negishi, Tadashi Muraoka, Terunobu Maeda, Fumiaki Takeuchi, Tadayoshi Kanao, Kazuo Kamimura, Tsuyoshi Sugio. Growth inhibition by tungsten in the sulfur-oxidizing bacterium Acidithiobacillus thiooxidans.
Bioscience, biotechnology, and biochemistry.
2005 Nov; 69(11):2073-80. doi:
10.1271/bbb.69.2073. [PMID: 16306687] - Prabhakara Reddy Nagareddy, Harish Vasudevan, John H McNeill. Oral administration of sodium tungstate improves cardiac performance in streptozotocin-induced diabetic rats.
Canadian journal of physiology and pharmacology.
2005 May; 83(5):405-11. doi:
10.1139/y05-026. [PMID: 15897922] - Sonica Pawa, Shakir Ali. Liver necrosis and fulminant hepatic failure in rats: protection by oxyanionic form of tungsten.
Biochimica et biophysica acta.
2004 Apr; 1688(3):210-22. doi:
10.1016/j.bbadis.2003.12.004. [PMID: 15062871] - M D Girón, J J Caballero, A M Vargas, M D Suárez, J J Guinovart, R Salto. Modulation of glucose transporters in rat diaphragm by sodium tungstate.
FEBS letters.
2003 May; 542(1-3):84-8. doi:
10.1016/s0014-5793(03)00352-1. [PMID: 12729903] - Sophie Le Lamer-Déchamps, Patrick Poucheret, Jean-Louis Pérez, Françoise Bressolle. Validation of an inductively coupled plasma-mass spectrometry method to quantify tungsten in human plasma. Determination of percentage binding to plasma proteins.
Clinica chimica acta; international journal of clinical chemistry.
2003 Jan; 327(1-2):39-46. doi:
10.1016/s0009-8981(02)00331-5. [PMID: 12482617] - S Le Lamer-Déchamps, P Poucheret, G Cros, F Bressolle. Influence of food and diabetes on pharmacokinetics of sodium tungstate in rat.
International journal of pharmaceutics.
2002 Nov; 248(1-2):131-9. doi:
10.1016/s0378-5173(02)00424-6. [PMID: 12429467] - Sophie Le Lamer, Gérard Cros, Carmen Piñol, Josepha Fernández-Alvarez, Françoise Bressolle. An application of population kinetics analysis to estimate pharmacokinetic parameters of sodium tungstate after multiple-dose during preclinical studies in rats.
Pharmacology & toxicology.
2002 Feb; 90(2):100-5. doi:
10.1034/j.1600-0773.2002.900208.x. [PMID: 12071424] - S Le Lamer, G Cros, J J Serrano, C Piñol, J Fernändez-Alvarez, F Bressolle. Estimation of pharmacokinetic parameters of sodium tungstate after multiple-dose during preclinical studies in beagle dogs.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2001 Dec; 14(4):323-9. doi:
10.1016/s0928-0987(01)00185-3. [PMID: 11684407] - A Barberà, R R Gomis, N Prats, J E Rodríguez-Gil, M Domingo, R Gomis, J J Guinovart. Tungstate is an effective antidiabetic agent in streptozotocin-induced diabetic rats: a long-term study.
Diabetologia.
2001 Apr; 44(4):507-13. doi:
10.1007/s001250100479. [PMID: 11357483] - T Sugio, H Kuwano, A Negishi, T Maeda, F Takeuchi, K Kamimura. Mechanism of growth inhibition by tungsten in Acidithiobacillus ferrooxidans.
Bioscience, biotechnology, and biochemistry.
2001 Mar; 65(3):555-62. doi:
10.1271/bbb.65.555. [PMID: 11330668] - S Le Lamer, P Poucheret, G Cros, R K de Richter, P A Bonnet, F Bressolle. Pharmacokinetics of sodium tungstate in rat and dog: a population approach.
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