Cefbuperazone (BioDeep_00000718403)

   


代谢物信息卡片


Cefbuperazone

化学式: C22H29N9O9S2 (627.1529584000001)
中文名称: 头孢拉宗
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCN1CCN(C(=O)C1=O)C(=O)NC(C(C)O)C(=O)NC2(C3N(C2=O)C(=C(CS3)CSC4=NN=NN4C)C(=O)O)OC
InChI: InChI=1S/C22H29N9O9S2/c1-5-29-6-7-30(16(35)15(29)34)20(39)23-12(10(2)32)14(33)24-22(40-4)18(38)31-13(17(36)37)11(8-41-19(22)31)9-42-21-25-26-27-28(21)3/h10,12,19,32H,5-9H2,1-4H3,(H,23,39)(H,24,33)(H,36,37)/t10-,12+,19+,22-/m0/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DC - Second-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002513 - Cephamycins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

1 个代谢物同义名

Cefbuperazone



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Dongbo Liu, Taohua Geng, Yiya Wang, Li Ding. Pharmacokinetic profile of cefbuperazone in healthy Chinese volunteers after single and multiple drip intravenous infusion by HPLC-MS/MS. Journal of pharmaceutical and biomedical analysis. 2016 Sep; 129(?):28-33. doi: 10.1016/j.jpba.2016.06.029. [PMID: 27394175]
  • M Okamoto, A Nakane, T Minagawa. Host resistance to an intragastric infection with Listeria monocytogenes in mice depends on cellular immunity and intestinal bacterial flora. Infection and immunity. 1994 Aug; 62(8):3080-5. doi: 10.1128/iai.62.8.3080-3085.1994. [PMID: 8039875]
  • N Satomi, A Sakurai, F Iimura, R Haranaka, K Haranaka. Preventive effect of several drugs against Pseudomonas aeruginosa infection and the toxicity of combined tumor necrosis factor with lipopolysaccharide: relationship between lethality and the arachidonic cascade. Biotherapy (Dordrecht, Netherlands). 1990; 2(3):227-34. doi: 10.1007/bf02173524. [PMID: 2169830]
  • Y Ikeda, Y Fukuoka, K Motomura, T Yasuda, T Nishino. Paradoxical activity of beta-lactam antibiotics against Proteus vulgaris in experimental infection in mice. Antimicrobial agents and chemotherapy. 1990 Jan; 34(1):94-7. doi: 10.1128/aac.34.1.94. [PMID: 2183712]
  • T Kumae, Y Saburi, M Nasu, J Misumi, N Kawata. Effects of cefbuperazone on the chemiluminescence of human neutrophils. Chemotherapy. 1989; 35(4):260-6. doi: 10.1159/000238680. [PMID: 2766868]
  • K Hidaka, H Yamamoto, S Harada, M Katano, H Fujiwara, T Mizoguchi, T Hisatsugu, K Yamaoka, T Kisu. [Excretion of antibiotics into bile and urine in patients with external cholecystostomy done in order to treat obstructive jaundice]. The Japanese journal of antibiotics. 1988 Sep; 41(9):1295-303. doi: NULL. [PMID: 3241327]
  • H Fjuii, D Niibori, K Okamura, H Hashimoto, S Tokunaka, S Yachiku, H Osanai. [Study of the prostatic tissue cefbuperazone (CBPZ) level]. Hinyokika kiyo. Acta urologica Japonica. 1988 May; 34(5):932-6. doi: NULL. [PMID: 2459941]
  • F Sasaki, N Takada, Y Hata, K Kyunoh, J Uchino. [A study of transfer of cefbuperazone into postoperative exudates in patients with cancer mastectomy or thyroidectomy]. The Japanese journal of antibiotics. 1988 Apr; 41(4):460-6. doi: NULL. [PMID: 3404652]
  • M Imaizumi, T Niimi, T Uchida, M Kajita, T Takahashi, Y Uchida, M Asaoka, Y Amano, T Ojika, T Abe. [Clinical study on transfer into lung tissue and postoperative prophylactic effect of new cephamycin antibiotics, particularly cefotetan and cefbuperazone]. The Japanese journal of antibiotics. 1988 Apr; 41(4):437-59. doi: NULL. [PMID: 3165475]
  • H Washida, H Sakagami, Y Iwase, S Sasaki, K Takeuchi, K Inuzuka. [Morphological studies of Escherichia coli in the urine of patients with acute simple cystitis treated with cefbuperazone]. Hinyokika kiyo. Acta urologica Japonica. 1987 Oct; 33(10):1712-7. doi: NULL. [PMID: 3328503]
  • H Izumi, S Ikeda, A Ishibashi, K Koshiba. [A study of prostatic tissue levels of cefbuperazone]. Hinyokika kiyo. Acta urologica Japonica. 1987 Aug; 33(8):1316-8. doi: NULL. [PMID: 2447766]
  • L Kager, B Brismar, A S Malmborg, C E Nord. Impact of cefbuperazone on the colonic microflora in patients undergoing colorectal surgery. Drugs under experimental and clinical research. 1986; 12(12):983-6. doi: NULL. [PMID: 3569009]
  • Y Kumasaka, H Nakahata, Y Hirai, K Imamura, K Takebe, I Suzuki, H Senda. [In vivo antibacterial activity of cefbuperazone. Synergy of cefbuperazone for bactericidal effect with human polymorphonuclear leukocytes]. The Japanese journal of antibiotics. 1986 Jan; 39(1):154-8. doi: NULL. [PMID: 3517405]
  • I Suzuki, H Senda, T Yokota. In vivo activity of cefbuperazone (T-1982) against various experimental infections in mice. The Journal of antibiotics. 1985 Feb; 38(2):249-58. doi: 10.7164/antibiotics.38.249. [PMID: 3997670]
  • K Seiga, Y Sugiyama. [Pharmacokinetic studies of cefbuperazone in the field of gynecology]. The Japanese journal of antibiotics. 1984 Dec; 37(12):2519-30. doi: NULL. [PMID: 6527403]
  • Y Watanabe, A Gonda, T Kidokoro. [Penetration of cefbuperazone, a new cephamycin antibiotic, into human peritoneal exudate]. The Japanese journal of antibiotics. 1984 Feb; 37(2):261-6. doi: NULL. [PMID: 6737691]
  • M Hongo, R Shimizu, S Hayashi, N Shirakawa, M Yoshinouchi, M Ando. [Study on transfer of T-1982 (cefbuperazone) into female genital organs]. The Japanese journal of antibiotics. 1983 May; 36(5):1033-40. doi: NULL. [PMID: 6620554]
  • K Iida, K Hayashi, M Miwa, M Shozu. [Fundamental and clinical study of T-1982 (cefbuperazone) in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):1005-9. doi: NULL. [PMID: 6620551]
  • K Taguchi, J Narita, K Goto, Y Shitara. [Fundamental study on T-1982 (cefbuperazone) in obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):919-24. doi: NULL. [PMID: 6620562]
  • N Cho, K Fukunaga, K Kunii, K Deguchi. [Fundamental and clinical studies of T-1982 (cefbuperazone) in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):939-55. doi: NULL. [PMID: 6352987]
  • K Hirabayashi, E Okada. [Fundamental and clinical studies on T-1982 (cefbuperazone) in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):1041-53. doi: NULL. [PMID: 6620555]
  • O Fukuda, C Tajima, T Tokunaga, H Mimori, A Hashimoto, M Maeyama. [Fundamental and clinical studies on T-1982 (cefbuperazone) in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):1097-102. doi: NULL. [PMID: 6620560]
  • H Nakamura, Y Iwata, S Hayashi. [Fundamental and clinical studies on T-1982 (cefbuperazone) in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):956-62. doi: NULL. [PMID: 6684699]
  • F Doko. [Basic and clinical studies of T-1982 (cefbuperazone) in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):1073-8. doi: NULL. [PMID: 6620557]
  • A Nakanishi, S Saito, M Shintani, I Shimamoto, M Ichijo, K Takashima, N Tamori. [Fundamental and clinical studies of T-1982 (cefbuperazone) in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1983 May; 36(5):1018-24. doi: NULL. [PMID: 6413727]
  • Y Toyonaga, Y Kurosu, N Koda, H Ida, H Mochizuki, K Kumagai, J Akatsuka, M Sugita, G Kawamura, T Okabe, M Hori, T Takahashi. [Laboratory and clinical studies on T-1982 (cefbuperazone) in the field of pediatrics]. The Japanese journal of antibiotics. 1983 Apr; 36(4):739-70. doi: NULL. [PMID: 6410101]
  • T Nishimura, K Tabuki, T Takashima, M Takagi. [Laboratory and clinical studies of T-1982 (cefbuperazone in pediatric field]. The Japanese journal of antibiotics. 1983 Apr; 36(4):838-48. doi: NULL. [PMID: 6348338]
  • S Nakazawa, H Sato, K Niino, Y Hirama, A Narita, H Suzuki, S Nakazawa, H Chikaoka, K Tazoe, Y Irino, Y Nakada, T Yoshihara. [Fundamental and clinical studies on T-1982 (cefbuperzone), a new cephamycin antibiotic, in the field of pediatrics]. The Japanese journal of antibiotics. 1983 Apr; 36(4):771-89. doi: NULL. [PMID: 6308296]
  • K Kazuoka, S Shimizu, Y Kawamura, H Kamiya, M Sakurai. [Fundamental and clinical studies on T-1982 (cefbuperazone) in the field of pediatrics]. The Japanese journal of antibiotics. 1983 Apr; 36(4):826-37. doi: NULL. [PMID: 6348337]
  • Y Kobayashi, T Haruta, S Kuroki, K Okura, S Tsuji, T Tsutsui. [Clinical evaluation for T-1982 (cefbuperazone) in the field of pediatric infection]. The Japanese journal of antibiotics. 1983 Apr; 36(4):849-54. doi: NULL. [PMID: 6348339]
  • J Mashiko, H Meguro, S Ohnari, B Kim, M Nakajo, T Tajima, R Fujii. [Clinical evaluation of T-1982 (cefbuperazone) in the pediatric infections]. The Japanese journal of antibiotics. 1983 Apr; 36(4):728-35. doi: NULL. [PMID: 6348335]
  • N Iwai, Y Taneda, A Sasaki, F Mizoguchi, H Nakamura. [Basic and clinical studies on T-1982 (cefbuperazone) in the field of pediatrics]. The Japanese journal of antibiotics. 1983 Apr; 36(4):803-25. doi: NULL. [PMID: 6348336]
  • Y Miyachi, T Nakashima, K Aso, A Ogawa, M Yafuso, K Kuno. [Laboratory and clinical studies of T-1982 (cefbuperazone) in pediatric infectious diseases]. The Japanese journal of antibiotics. 1983 Apr; 36(4):790-802. doi: NULL. [PMID: 6410102]
  • I Saikawa, A Takai, Y Nakashima, T Ikegami, H Hayakawa, M Noguchi, H Yamauchi, H Shimizu. [Studies on absorption, distribution and excretion of 14C labelled sodium 7 beta-[(2R, 3S)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-3-hydroxybutanamido]-7-methoxy-3-[(1-methyl-1H-tetrazol-5-YL)thiomethyl]-3-cephem-4-carboxylate (14C-T-1982) in mice and rats]. The Japanese journal of antibiotics. 1982 Sep; 35(9):2163-73. doi: NULL. [PMID: 7143717]
  • I Saikawa, A Takai, Y Nakashima, T Ikegami, H Hayakawa, M Noguchi, H Yamauchi, H Shimizu. [The whole body autoradiographic studies on the distribution of 14C-labelled sodium 7 beta-[(2R, 3S)-2-(4-ethyl-2, 3-dioxo-1-piperazine-carboxamido)-3-hydroxybutanamido]-7 alpha-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylate (14C-T-1982) in mice]. The Japanese journal of antibiotics. 1982 Sep; 35(9):2159-62. doi: NULL. [PMID: 7143716]
  • A Takai, S Hirai, I Watanabe, T Hiraiwa, N Abe, H Arai, M Omori, K Tanada, N Senda, K Hashiba, K Matsukura, K Takata, H Okami. [General pharmacology of T-1982, a new cephamycin antibiotic]. The Japanese journal of antibiotics. 1982 Sep; 35(9):2139-54. doi: NULL. [PMID: 7143714]