Cetraxate HCl (BioDeep_00000718357)
代谢物信息卡片
化学式: C17H24ClNO4 (341.1394)
中文名称: 盐酸西曲酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(CCC1CN)C(=O)OC2=CC=C(C=C2)CCC(=O)O.Cl
InChI: InChI=1S/C17H23NO4.ClH/c18-11-13-1-6-14(7-2-13)17(21)22-15-8-3-12(4-9-15)5-10-16(19)20
描述信息
C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
同义名列表
33 个代谢物同义名
Cetraxate hydrochloride; Cetraxate HCl; USROQQUKEBHOFF-UHFFFAOYSA-N; 08IT6P8VHY; 3-(4-((1r,4r)-4-(aminomethyl)cyclohexanecarbonyloxy); 3-(4-((1r,4r)-4-(aminomethyl)cyclohexanecarbonyloxy)phenyl)propanoic acid; 3-[4-[[trans-4-(Aminomethyl)cyclohexyl]carbonyloxy]phenyl]propanoic Acid Hydrochloride; 3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid;hydrochloride; 3-{4-[4-(aminomethyl)cyclohexanecarbonyloxy]phenyl}propanoic acid hydrochloride; 4-(2-carboxyethyl)phenyl-trans-4-aminomethylcyclohexane carboxylate hydrochloride; 4'-(2-Carboxyethyl)phenyl-trans-4-aminomethylcyclohexane carboxylate hydrochloride; Benzenepropanoic acid, 4-(((4-(aminomethyl)cyclohexyl)carbonyl)oxy)-, hydrochloride, trans-; cetraxate; Cetraxate (hydrochloride); Cetraxate hydrochloride (JP17/USAN); CETRAXATE HYDROCHLORIDE [JAN]; CETRAXATE HYDROCHLORIDE [MART.]; CETRAXATE HYDROCHLORIDE [MI]; Cetraxate hydrochloride [USAN:JAN]; CETRAXATE HYDROCHLORIDE [USAN]; CETRAXATE HYDROCHLORIDE [WHO-DD]; cetraxate hydrochloride, (trans)-isomer; Cetraxate, Hydrochloride; Cetraxato clorhidrato; Cetraxato clorhidrato [Spanish]; Hydrocinnamic acid, p-hydroxy-, 4-(aminomethyl)cyclohexanecarboxylate hydrochloride, trans-; Neuer; Neuer (TN); p-Hydroxyhydrocinnamic acid trans-4-(aminomethyl)cyclohexanecarboxylate, hydrochloride; phenyl)propanoic acid hydrochloride; Tox21_112210; Tox21_112210_1; UNII-08IT6P8VHY
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Fumihiko Katagiri, Toru Shiga, Yuhki Sato, Shin Inoue, Hiroki Itoh, Masaharu Takeyama. Comparison of the effects of cytoprotective drugs on human plasma adrenocorticotropic hormone and cortisol levels with continual stress exposure.
Biological & pharmaceutical bulletin.
2005 Nov; 28(11):2146-8. doi:
10.1248/bpb.28.2146. [PMID: 16272707] - Sang-Yong Seol, Myung-Hwan Kim, Jong-Sun Ryu, Myung-Gyu Choi, Dong-Wook Shin, Byoung-Ok Ahn. DA-9601 for erosive gastritis: results of a double-blind placebo-controlled phase III clinical trial.
World journal of gastroenterology.
2004 Aug; 10(16):2379-82. doi:
10.3748/wjg.v10.i16.2379. [PMID: 15285023] - Fumihiko Katagiri, Yuhki Sato, Hiroki Itoh, Masaharu Takeyama. Cetraxate raises levels of calcitonin gene-related peptide and substance P in human plasma.
The Journal of pharmacy and pharmacology.
2004 Apr; 56(4):557-61. doi:
10.1211/0022357023169. [PMID: 15099451] - M Yuzurihara, Y Ikarashi, Y Kase, Y Torimaru, A Ishige, Y Maruyama. Effect of Saiboku-to, an Oriental Herbal Medicine, on gastric lesion induced by restraint water-immersion stress or by ethanol treatment.
The Journal of pharmacy and pharmacology.
1999 Apr; 51(4):483-90. doi:
10.1211/0022357991772547. [PMID: 10385222] - M Uchida, N Nishimura, N Misaki, Y Ikarashi, M Kobayashi, O Kawano. [Effect of anti-ulcer drugs and PGE2 on the proliferation of rat gastric cultured cells].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1990 Apr; 95(4):185-90. doi:
10.1254/fpj.95.4_185. [PMID: 2370034] - C M Svahn, F Merenyi, L Karlson, L Widlund, M Grälls. Tranexamic acid derivatives with enhanced absorption.
Journal of medicinal chemistry.
1986 Apr; 29(4):448-53. doi:
10.1021/jm00154a004. [PMID: 3959024] - H Sumi, N Toki. Inhibitors of the acrosomal proteinase acrosin: human urinary trypsin inhibitor (UTI) and 4-(2-carboxyethyl) phenyl trans 4-aminomethylcyclohexanecarboxylate hydrochloride (DV-1006).
Experientia.
1980 Sep; 36(9):1103-4. doi:
10.1007/bf01965994. [PMID: 6998719]
