oxyphenbutazone hydrate (BioDeep_00000717605)
代谢物信息卡片
化学式: C19H22N2O4 (342.1579)
中文名称: 羟基保泰松
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3.O
InChI: InChI=1S/C19H20N2O3.H2O/c1-2-3-9-17-18(23)20(14-7-5-4-6-8-14)21(19(17)24)15-10-12-16(22)13-11-15
描述信息
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:76259
- PubChem: 104811
- ChEMBL: CHEMBL3989676
- MeSH: Oxyphenbutazone
- CAS: 76576-51-7
- CAS: 7081-38-1
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Shakir Saleem, Ruqaiyah Khan, Muhammad Afzal, Imran Kazmi. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/β-catenin signaling pathway.
Molecular and cellular biochemistry.
2018 Jul; 444(1-2):187-196. doi:
10.1007/s11010-017-3243-2. [PMID: 29204817] - Joe O Boison, Patricia Dowling, Johanna L Matus, Jana Kinar, Ron Johnson. The Analysis of Phenylbutazone and Its Active Metabolite, Oxyphenbutazone, in Equine Tissues (Muscle, Kidney, and Liver), Urine, and Serum by LC-MS/MS.
Journal of AOAC International.
2017 Jul; 100(4):1110-1122. doi:
10.5740/jaoacint.16-0127. [PMID: 28145218] - B C Sallustio, B A Fairchild, P R Pannall. Interaction of human serum albumin with the electrophilic metabolite 1-O-gemfibrozil-beta-D-glucuronide.
Drug metabolism and disposition: the biological fate of chemicals.
1997 Jan; 25(1):55-60. doi:
NULL. [PMID: 9010630] - P Claeson, U Pongprayoon, T Sematong, P Tuchinada, V Reutrakul, P Soontornsaratune, W C Taylor. Non-phenolic linear diarylheptanoids from Curcuma xanthorrhiza: a novel type of topical anti-inflammatory agents: structure-activity relationship.
Planta medica.
1996 Jun; 62(3):236-40. doi:
10.1055/s-2006-957867. [PMID: 8693036] - M Tariq, A M Ageel, M A al-Yahya, J S Mossa, M S al-Said. Anti-inflammatory activity of Teucrium polium.
International journal of tissue reactions.
1989; 11(4):185-8. doi:
". [PMID: 2634627] - J M Bailey, J Butler. Anti-inflammatory drugs in experimental atherosclerosis. Part 6. Combination therapy with steroid and non-steroid agents.
Atherosclerosis.
1985 Feb; 54(2):205-12. doi:
10.1016/0021-9150(85)90179-0. [PMID: 3986018] - S Somasundaram, J Sadique, A Subramoniam. Influence of extra-intestinal inflammation on the in vitro absorption of 14C-glucose and the effects of anti-inflammatory drugs in the jejunum of rats.
Clinical and experimental pharmacology & physiology.
1983 Mar; 10(2):147-52. doi:
10.1111/j.1440-1681.1983.tb00180.x. [PMID: 6872332] - T Tsukui, N Takasu, T Onaya, T Yamada. Effect of nonsteroidal antiinflammatory drugs on plasma protein-thyroxine interaction.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1974 Jun; 146(2):494-8. doi:
10.3181/00379727-146-38133. [PMID: 4365312] - D S Davies, S S Thorgeirsson. Individual differences in the plasma half-lives of lipid soluble drugs in man.
Acta pharmacologica et toxicologica.
1971; 29 Suppl 3(?):181-90. doi:
10.1111/j.1600-0773.1971.tb03298.x. [PMID: 5316400] - E Fujihira, S Otomo. [Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. II. On UV-induced canine erythrocyte hemolysisand lipid peroxidation, on UV-induced peroxide formation in extracted lipid, and on irradiated lipid-induced hemolysis].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
1970 Nov; 90(11):1355-62. doi:
10.1248/yakushi1947.90.11_1355. [PMID: 5530443] - S Otomo, E Fujihira. [Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. I. On hemolysis and lipid peroxidation induced by H202 in canine erythrocyte].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
1970 Nov; 90(11):1347-54. doi:
10.1248/yakushi1947.90.11_1347. [PMID: 5531325] - A Maggiora, H Lozeron, W Jadassohn. [The modification of radiation effects by means of various substances (Vicia faba and guinea pig test)].
Strahlentherapie.
1966 Mar; 129(3):438-45. doi:
". [PMID: 4383593]
