Bay 11-7085 (BioDeep_00000717348)

   


代谢物信息卡片


(E)-3-(4-Tert-butylphenylsulfonyl)acrylonitrile

化学式: C13H15NO2S (249.082345)
中文名称: (2E)-3-[[4-叔丁基苯基]磺酰基]-2-丙烯腈
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)C=CC#N
InChI: InChI=1S/C13H15NO2S/c1-13(2,3)11-5-7-12(8-6-11)17(15,16)10-4-9-14/h4-8,10H,1-3H3/b10-4+

描述信息

同义名列表

2 个代谢物同义名

(E)-3-(4-Tert-butylphenylsulfonyl)acrylonitrile; Bay 11-7085



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Linzhou Yin, Pengyu Liu, Yue Jin, Zunxi Ning, Yiren Yang, Huiyuan Gao. Ferroptosis-related small-molecule compounds in cancer therapy: Strategies and applications. European journal of medicinal chemistry. 2022 Dec; 244(?):114861. doi: 10.1016/j.ejmech.2022.114861. [PMID: 36332549]
  • B Mora-Ramiro, M Jiménez-Estrada, A Zentella-Dehesa, J L Ventura-Gallegos, L E Gomez-Quiroz, W Rosiles-Alanis, F J Alarcón-Aguilar, J C Almanza-Pérez. Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages. Journal of natural products. 2020 08; 83(8):2447-2455. doi: 10.1021/acs.jnatprod.0c00300. [PMID: 32672964]
  • Ling-Chu Chang, Shih-Kai Chiang, Shuen-Ei Chen, Yung-Luen Yu, Ruey-Hwang Chou, Wei-Chao Chang. Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis. Cancer letters. 2018 03; 416(?):124-137. doi: 10.1016/j.canlet.2017.12.025. [PMID: 29274359]
  • Tao Zuo, Minghui Zhu, Wenming Xu, Zhixia Wang, Hang Song. Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2017; 43(5):1855-1865. doi: 10.1159/000484074. [PMID: 29049992]
  • Yuqin Wang, Zuhui Zhang, Laihe Zhang, Xinxin Li, Rui Lu, Peipei Xu, Xuhong Zhang, Mali Dai, Xiaodan Dai, Jia Qu, Fan Lu, Zailong Chi. S100A8 promotes migration and infiltration of inflammatory cells in acute anterior uveitis. Scientific reports. 2016 10; 6(?):36140. doi: 10.1038/srep36140. [PMID: 27786310]
  • Biserka Relic, Edith Charlier, Celine Deroyer, Olivier Malaise, Sophie Neuville, Aline Desoroux, Philippe Gillet, Dominique de Seny, Michel G Malaise. BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death. Oncotarget. 2016 Apr; 7(17):23370-82. doi: 10.18632/oncotarget.8042. [PMID: 26993765]
  • Fernanda Fredericksen, Gonzalo Carrasco, Melina Villalba, Víctor H Olavarría. Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-κB signaling pathway. Molecular immunology. 2015 Dec; 68(2 Pt A):213-22. doi: 10.1016/j.molimm.2015.08.010. [PMID: 26330089]
  • X Zhou, R Ringseis, G Wen, K Eder. The pro-inflammatory cytokine tumor necrosis factor α stimulates expression of the carnitine transporter OCTN2 (novel organic cation transporter 2) and carnitine uptake via nuclear factor-κB in Madin-Darby bovine kidney cells. Journal of dairy science. 2015 Jun; 98(6):3840-8. doi: 10.3168/jds.2014-9044. [PMID: 25892691]
  • Jia-hong Xue, Zuyi Yuan, Yue Wu, Yan Liu, Yan Zhao, Wei-ping Zhang, Yu-ling Tian, Wei-min Liu, Yu Liu, Chiharu Kishimoto. High glucose promotes intracellular lipid accumulation in vascular smooth muscle cells by impairing cholesterol influx and efflux balance. Cardiovascular research. 2010 Apr; 86(1):141-50. doi: 10.1093/cvr/cvp388. [PMID: 20007688]
  • Kazuto Takahashi, Shinya Yamaguchi, Tatsuhiro Shimoyama, Hiroyuki Seki, Kaoru Miyokawa, Hidenori Katsuta, Toshiaki Tanaka, Katsuhiko Yoshimoto, Hideki Ohno, Shinya Nagamatsu, Hitoshi Ishida. JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro. American journal of physiology. Endocrinology and metabolism. 2008 May; 294(5):E898-909. doi: 10.1152/ajpendo.00131.2007. [PMID: 18303122]
  • Carole Sourbier, Sabrina Danilin, Véronique Lindner, Jacques Steger, Sylvie Rothhut, Nicolas Meyer, Didier Jacqmin, Jean-Jacques Helwig, Hervé Lang, Thierry Massfelder. Targeting the nuclear factor-kappaB rescue pathway has promising future in human renal cell carcinoma therapy. Cancer research. 2007 Dec; 67(24):11668-76. doi: 10.1158/0008-5472.can-07-0632. [PMID: 18089796]
  • Pu Qin, Xiaoyan Tang, M Merle Elloso, Douglas C Harnish. Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38. American journal of physiology. Heart and circulatory physiology. 2006 Aug; 291(2):H741-7. doi: 10.1152/ajpheart.01182.2005. [PMID: 16582018]
  • S Hernández-Gutierrez, I García-Peláez, A Zentella-Dehesa, M Ramos-Kuri, P Hernández-Franco, F Hernández-Sánchez, E Rojas. NF-kappaB signaling blockade by Bay 11-7085 during early cardiac morphogenesis induces alterations of the outflow tract in chicken heart. Apoptosis : an international journal on programmed cell death. 2006 Jul; 11(7):1101-9. doi: 10.1007/s10495-006-6984-z. [PMID: 16699956]
  • Ann Beers, Michael J Haas, Norman C W Wong, Arshag D Mooradian. Inhibition of apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling. Biochemistry. 2006 Feb; 45(7):2408-13. doi: 10.1021/bi0518040. [PMID: 16475830]