N-Acetyl-S-(2-carbamoylethyl)-L-Cysteine (BioDeep_00000717010)
代谢物信息卡片
N-Acetyl-S-(2-carbamoylethyl)-L-Cysteine
化学式: C8H14N2O4S (234.0674244)
中文名称: N-乙酰基-S-(氨基甲酰基乙基)-L-半胱氨酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)NC(CSCCC(=O)N)C(=O)O
InChI: InChI=1S/C8H14N2O4S/c1-5(11)10-6(8(13)14)4-15-3-2-7(9)12/h6H,2-4H2,1H3,(H2,9,12)(H,10,11)(H,13,14)/t6-/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Banrida Wahlang, Tyler C Gripshover, Hong Gao, Tatiana Krivokhizhina, Rachel J Keith, Israel D Sithu, Shesh N Rai, Aruni Bhatnagar, Craig J McClain, Sanjay Srivastava, Mathew C Cave. Associations Between Residential Exposure to Volatile Organic Compounds and Liver Injury Markers.
Toxicological sciences : an official journal of the Society of Toxicology.
2021 12; 185(1):50-63. doi:
10.1093/toxsci/kfab119. [PMID: 34668566] - Chih-Chun Jean Huang, Chia-Fang Wu, Wei-Chung Shih, Yu-Syuan Luo, Ming-Feng Chen, Chien-Ming Li, Saou-Hsing Liou, Wen-Sheng Chung, Su-Yin Chiang, Kuen-Yuh Wu. Potential Association of Urinary N7-(2-Carbamoyl-2-hydroxyethyl) Guanine with Dietary Acrylamide Intake of Smokers and Nonsmokers.
Chemical research in toxicology.
2015 Jan; 28(1):43-50. doi:
10.1021/tx500265p. [PMID: 25486454] - Chien-Yu Lin, Lian-Yu Lin, Yu-Chuan Chen, Li-Li Wen, Kuo-Liong Chien, Fung-Chang Sung, Pau-Chung Chen, Ta-Chen Su. Association between measurements of thyroid function and the acrylamide metabolite N-Acetyl-S-(propionamide)-cysteine in adolescents and young adults.
Environmental research.
2015 Jan; 136(?):246-52. doi:
10.1016/j.envres.2014.08.043. [PMID: 25460643] - Chien-Yu Lin, Hui-Ling Lee, Yu-Chuan Chen, Guang-Wen Lien, Lain-Yu Lin, Li-Li Wen, Chien-Chang Liao, Kuo-Liong Chien, Fung-Chang Sung, Pau-Chung Chen, Ta-Chen Su. Positive association between urinary levels of 8-hydroxydeoxyguanosine and the acrylamide metabolite N-acetyl-S-(propionamide)-cysteine in adolescents and young adults.
Journal of hazardous materials.
2013 Oct; 261(?):372-7. doi:
10.1016/j.jhazmat.2013.06.069. [PMID: 23959257] - William J Moorman, Susan S Reutman, Peter B Shaw, Leo Michael Blade, David Marlow, Hubert Vesper, John C Clark, Steven M Schrader. Occupational exposure to acrylamide in closed system production plants: air levels and biomonitoring.
Journal of toxicology and environmental health. Part A.
2012; 75(2):100-11. doi:
10.1080/15287394.2011.615109. [PMID: 22129237] - Yu-Fang Huang, Mei-Lien Chen, Saou-Hsing Liou, Ming-Feng Chen, Shi-Nian Uang, Kuen-Yuh Wu. Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide.
Toxicology letters.
2011 Jun; 203(2):118-26. doi:
10.1016/j.toxlet.2011.03.008. [PMID: 21402133] - Eva C Hartmann, Julia M Latzin, Birgit K Schindler, Holger M Koch, Jürgen Angerer. Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide.
Archives of toxicology.
2011 Jun; 85(6):601-6. doi:
10.1007/s00204-010-0605-x. [PMID: 20953585] - Eva Katharina Kopp, Wolfgang Dekant. Toxicokinetics of acrylamide in rats and humans following single oral administration of low doses.
Toxicology and applied pharmacology.
2009 Mar; 235(2):135-42. doi:
10.1016/j.taap.2008.12.001. [PMID: 19118568] - Thomas Schwend, Jens Schabacker, Bernhard Wetterauer, Michael Wink. Uptake of S-(3-amino-3-oxopropyl)-cysteine by Caco-2 cells.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2008 Nov; 63(11-12):913-8. doi:
10.1515/znc-2008-11-1223. [PMID: 19227845] - Thomas Schettgen, Anita Musiol, Thomas Kraus. Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and N,N-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2008 Sep; 22(17):2629-38. doi:
10.1002/rcm.3659. [PMID: 18666198] - Eva C Hartmann, Melanie I Boettcher, Thomas Schettgen, Hermann Fromme, Hans Drexler, Jürgen Angerer. Hemoglobin adducts and mercapturic acid excretion of acrylamide and glycidamide in one study population.
Journal of agricultural and food chemistry.
2008 Aug; 56(15):6061-8. doi:
10.1021/jf800277h. [PMID: 18624428] - Sean M Hays, Lesa L Aylward. Biomonitoring Equivalents (BE) dossier for acrylamide (AA) (CAS No. 79-06-1).
Regulatory toxicology and pharmacology : RTP.
2008 Aug; 51(3 Suppl):S57-67. doi:
10.1016/j.yrtph.2008.05.010. [PMID: 18583007] - Chih-Chun Jean Huang, Chien-Ming Li, Chia-Fang Wu, Su-Ping Jao, Kuen-Yuh Wu. Analysis of urinary N-acetyl-S-(propionamide)-cysteine as a biomarker for the assessment of acrylamide exposure in smokers.
Environmental research.
2007 Jul; 104(3):346-51. doi:
10.1016/j.envres.2007.03.005. [PMID: 17467688] - Melanie I Boettcher, Hermann M Bolt, Hans Drexler, Jürgen Angerer. Excretion of mercapturic acids of acrylamide and glycidamide in human urine after single oral administration of deuterium-labelled acrylamide.
Archives of toxicology.
2006 Feb; 80(2):55-61. doi:
10.1007/s00204-005-0011-y. [PMID: 16180013] - Uwe Fuhr, Melanie I Boettcher, Martina Kinzig-Schippers, Alexandra Weyer, Alexander Jetter, Andreas Lazar, Dirk Taubert, Dorota Tomalik-Scharte, Panagiota Pournara, Verena Jakob, Stefanie Harlfinger, Tobias Klaassen, Albrecht Berkessel, Jürgen Angerer, Fritz Sörgel, Edgar Schömig. Toxicokinetics of acrylamide in humans after ingestion of a defined dose in a test meal to improve risk assessment for acrylamide carcinogenicity.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2006 Feb; 15(2):266-71. doi:
10.1158/1055-9965.epi-05-0647. [PMID: 16492914] - T Bjellaas, K Janák, E Lundanes, L Kronberg, G Becher. Determination and quantification of urinary metabolites after dietary exposure to acrylamide.
Xenobiotica; the fate of foreign compounds in biological systems.
2005 Oct; 35(10-11):1003-18. doi:
10.1080/00498250500356506. [PMID: 16393858] - Timothy R Fennell, Susan C J Sumner, Rodney W Snyder, Jason Burgess, Rebecca Spicer, William E Bridson, Marvin A Friedman. Metabolism and hemoglobin adduct formation of acrylamide in humans.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 May; 85(1):447-59. doi:
10.1093/toxsci/kfi069. [PMID: 15625188] - Chien-Ming Li, Chiung-Wen Hu, Kuen-Yuh Wu. Quantification of urinary N-acetyl-S- (propionamide)cysteine using an on-line clean-up system coupled with liquid chromatography/tandem mass spectrometry.
Journal of mass spectrometry : JMS.
2005 Apr; 40(4):511-5. doi:
10.1002/jms.823. [PMID: 15712353] - Melanie Isabell Boettcher, Thomas Schettgen, Birgitta Kütting, Monika Pischetsrieder, Jürgen Angerer. Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general population.
Mutation research.
2005 Feb; 580(1-2):167-76. doi:
10.1016/j.mrgentox.2004.11.010. [PMID: 15668118] - Y Q Wu, A R Yu, X Y Tang, J Zhang, T Cui. Determination of acrylamide metabolite, mercapturic acid by high performance liquid chromatography.
Biomedical and environmental sciences : BES.
1993 Sep; 6(3):273-80. doi:
NULL. [PMID: 8292272] - Y Q Wu. [Determination of acrylamide metabolite, mercapturic acid by high-performance liquid chromatography].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].
1993 Jul; 27(4):221-3. doi:
NULL. [PMID: 8143519]