Sodium feredetate (BioDeep_00000715602)

   


代谢物信息卡片


EDTA FERRIC-SODIUM SALT

化学式: C10H12FeN2NaO8 (366.9840722)
中文名称: 乙二胺四乙酸铁钠盐, EDTA铁-钠盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Fe+3]
InChI: +3

描述信息

B - Blood and blood forming organs > B03 - Antianemic preparations > B03A - Iron preparations > B03AB - Iron trivalent, oral preparations
D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents
D006401 - Hematologic Agents > D006397 - Hematinics > D005290 - Ferric Compounds

同义名列表

3 个代谢物同义名

EDTA FERRIC-SODIUM SALT; EDTA ferric sodium salt; Sodium feredetate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Agnieszka I Piotrowicz-Cieślak, Maciej Maciejczyk, Małgorzata Margas, Dariusz Rydzyński, Hanna Grajek, Dariusz J Michalczyk, Janusz Wasilewski, Bogdan Smyk. Studies on the Efficiency of Iron Release from Fe(III)-EDTA and Fe(III)-Cit and the Suitability of These Compounds for Tetracycline Degradation. Molecules (Basel, Switzerland). 2022 Dec; 27(23):. doi: 10.3390/molecules27238498. [PMID: 36500591]
  • Joyce Grazielle Siqueira Silva, Ana Paula Rebellato, Júlia Silvestre de Abreu, Ralf Greiner, Juliana Azevedo Lima Pallone. Impact of the fortification of a rice beverage with different calcium and iron sources on calcium and iron bioaccessibility. Food research international (Ottawa, Ont.). 2022 11; 161(?):111830. doi: 10.1016/j.foodres.2022.111830. [PMID: 36192962]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Jie Xiao, Yoo Gyeong Park, Ge Guo, Byoung Ryong Jeong. Effect of Iron Source and Medium pH on Growth and Development of Sorbus commixta In Vitro. International journal of molecular sciences. 2020 Dec; 22(1):. doi: 10.3390/ijms22010133. [PMID: 33374479]
  • N Marchitto, A Curcio, N Iannarelli, A Petrucci, A Romano, M Pironti, P T Paparello, G Raimondi. A pilot study on secondary anemia in 'frailty' patients treated with Ferric Sodium EDTA in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine: safety of treatment explored by HRV non-linear analysis as predictive factor of cardiovascular tolerability. European review for medical and pharmacological sciences. 2020 07; 24(14):7776-7783. doi: 10.26355/eurrev_202007_22280. [PMID: 32744704]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Tamanna A Jahan, Albert Vandenberg, Raymond P Glahn, Robert T Tyler, Martin J T Reaney, Bunyamin Tar'an. Iron Fortification and Bioavailability of Chickpea (Cicer arietinum L.) Seeds and Flour. Nutrients. 2019 Sep; 11(9):. doi: 10.3390/nu11092240. [PMID: 31540391]
  • Rajib Podder, Diane M DellaValle, Robert T Tyler, Raymond P Glahn, Elad Tako, Albert Vandenberg. Relative Bioavailability of Iron in Bangladeshi Traditional Meals Prepared with Iron-Fortified Lentil Dal. Nutrients. 2018 Mar; 10(3):. doi: 10.3390/nu10030354. [PMID: 29543712]
  • Rajib Podder, Shaan M Khan, Bunyamin Tar'an, Robert T Tyler, Carol J Henry, Chowdhury Jalal, Phyllis J Shand, Albert Vandenberg. Sensory Acceptability of Iron-Fortified Red Lentil (Lens culinaris Medik.) Dal. Journal of food science. 2018 Mar; 83(3):804-813. doi: 10.1111/1750-3841.14066. [PMID: 29469948]
  • Daniela Paganini, Mary A Uyoga, Guus A M Kortman, Colin I Cercamondi, Diego Moretti, Tanja Barth-Jaeggi, Clarissa Schwab, Jos Boekhorst, Harro M Timmerman, Christophe Lacroix, Simon Karanja, Michael B Zimmermann. Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan infants. Gut. 2017 11; 66(11):1956-1967. doi: 10.1136/gutjnl-2017-314418. [PMID: 28774885]
  • Dominik Glinz, Rita Wegmüller, Mamadou Ouattara, Victorine G Diakité, Grant J Aaron, Lorenz Hofer, Michael B Zimmermann, Lukas G Adiossan, Jürg Utzinger, Eliézer K N'Goran, Richard F Hurrell. Iron Fortified Complementary Foods Containing a Mixture of Sodium Iron EDTA with Either Ferrous Fumarate or Ferric Pyrophosphate Reduce Iron Deficiency Anemia in 12- to 36-Month-Old Children in a Malaria Endemic Setting: A Secondary Analysis of a Cluster-Randomized Controlled Trial. Nutrients. 2017 Jul; 9(7):. doi: 10.3390/nu9070759. [PMID: 28708072]
  • Emily M Teshome, Pauline E A Andang'o, Victor Osoti, Sofie R Terwel, Walter Otieno, Ayşe Y Demir, Andrew M Prentice, Hans Verhoef. Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children. BMC medicine. 2017 04; 15(1):89. doi: 10.1186/s12916-017-0839-z. [PMID: 28449690]
  • C Icard-Vernière, C Picq, L Courbis, C Mouquet-Rivier. The type of fortificant and the leaf matrix both influence iron and zinc bioaccessibility in iron-fortified green leafy vegetable sauces from Burkina Faso. Food & function. 2016 Feb; 7(2):1103-10. doi: 10.1039/c5fo01227a. [PMID: 26787350]
  • Tanja Barth-Jaeggi, Diego Moretti, Jane Kvalsvig, Penny A Holding, Jane Njenga, Alice Mwangi, Meera K Chhagan, Christophe Lacroix, Michael B Zimmermann. In-home fortification with 2.5 mg iron as NaFeEDTA does not reduce anaemia but increases weight gain: a randomised controlled trial in Kenyan infants. Maternal & child nutrition. 2015 Dec; 11 Suppl 4(?):151-62. doi: 10.1111/mcn.12163. [PMID: 25420455]
  • Dominik Glinz, Richard F Hurrell, Mamadou Ouattara, Michael B Zimmermann, Gary M Brittenham, Lukas G Adiossan, Aurélie A Righetti, Burkhardt Seifert, Victorine G Diakité, Jürg Utzinger, Eliézer K N'Goran, Rita Wegmüller. The effect of iron-fortified complementary food and intermittent preventive treatment of malaria on anaemia in 12- to 36-month-old children: a cluster-randomised controlled trial. Malaria journal. 2015 Sep; 14(?):347. doi: 10.1186/s12936-015-0872-3. [PMID: 26377199]
  • Min Li, Jinghuan Wu, Tongxiang Ren, Rui Wang, Weidong Li, Jianhua Piao, Jun Wang, Xiaoguang Yang. Effect of NaFeEDTA-fortified soy sauce on zinc absorption in children. Food & function. 2015 Mar; 6(3):788-92. doi: 10.1039/c4fo00722k. [PMID: 25582850]
  • Seher Bahar Aciksoz, Levent Ozturk, Atilla Yazici, Ismail Cakmak. Inclusion of urea in a 59FeEDTA solution stimulated leaf penetration and translocation of 59Fe within wheat plants. Physiologia plantarum. 2014 Jul; 151(3):348-57. doi: 10.1111/ppl.12198. [PMID: 24673110]
  • Colin I Cercamondi, Ines M Egli, Evariste Mitchikpe, Felicien Tossou, Joamel Hessou, Christophe Zeder, Joseph D Hounhouigan, Richard F Hurrell. Iron bioavailability from a lipid-based complementary food fortificant mixed with millet porridge can be optimized by adding phytase and ascorbic acid but not by using a mixture of ferrous sulfate and sodium iron EDTA. The Journal of nutrition. 2013 Aug; 143(8):1233-9. doi: 10.3945/jn.113.175075. [PMID: 23761652]
  • Klaus Schümann, Noel W Solomons, Monica Orozco, Maria Eugenia Romero-Abal, Guenter Weiss. Differences in circulating non-transferrin-bound iron after oral administration of ferrous sulfate, sodium iron EDTA, or iron polymaltose in women with marginal iron stores. Food and nutrition bulletin. 2013 Jun; 34(2):185-93. doi: 10.1177/156482651303400207. [PMID: 23964391]
  • Chan Theary, Dora Panagides, Arnaud Laillou, Saphoon Vonthanak, Chheng Kanarath, Chhea Chhorvann, Pol Sambath, Sol Sowath, Regina Moench-Pfanner. Fish sauce, soy sauce, and vegetable oil fortification in Cambodia: where do we stand to date?. Food and nutrition bulletin. 2013 Jun; 34(2 Suppl):S62-71. doi: 10.1177/15648265130342s108. [PMID: 24049997]
  • Catherine W Macharia-Mutie, Diego Moretti, Natalie Van den Briel, Agnes M Omusundi, Alice M Mwangi, Frans J Kok, Michael B Zimmermann, Inge D Brouwer. Maize porridge enriched with a micronutrient powder containing low-dose iron as NaFeEDTA but not amaranth grain flour reduces anemia and iron deficiency in Kenyan preschool children. The Journal of nutrition. 2012 Sep; 142(9):1756-63. doi: 10.3945/jn.112.157578. [PMID: 22810982]
  • Vani Amalrajan, Prashanth Thankachan, Sumithra Selvam, Anura Kurpad. Effect of wheat flour fortified with sodium iron EDTA on urinary zinc excretion in school-aged children. Food and nutrition bulletin. 2012 Sep; 33(3):177-9. doi: 10.1177/156482651203300301. [PMID: 23156119]
  • Maria G Galán, Carolina E Cagnasso, Silvina R Drago. Study of EDTA intake of children for potential use of FeNaEDTA for breakfast cereal fortification. Archivos latinoamericanos de nutricion. 2012 Sep; 62(3):290-4. doi: ". [PMID: 24617032]
  • Tarun Gera, Harshpal Singh Sachdev, Erick Boy. Effect of iron-fortified foods on hematologic and biological outcomes: systematic review of randomized controlled trials. The American journal of clinical nutrition. 2012 Aug; 96(2):309-24. doi: 10.3945/ajcn.111.031500. [PMID: 22760566]
  • Wei Xia, Xin Zhang, Jiajia Wang, Caihong Sun, Lijie Wu. Survey of anaemia and Helicobacter pylori infection in adolescent girls in Suihua, China and enhancement of iron intervention effects by H. pylori eradication. The British journal of nutrition. 2012 Jul; 108(2):357-62. doi: 10.1017/s0007114511005666. [PMID: 22004585]
  • Klaus Schümann, Noel W Solomons, Maria-Eugenia Romero-Abal, Monica Orozco, Guenter Weiss, Jo Marx. Oral administration of ferrous sulfate, but not of iron polymaltose or sodium iron ethylenediaminetetraacetic acid (NaFeEDTA), results in a substantial increase of non-transferrin-bound iron in healthy iron-adequate men. Food and nutrition bulletin. 2012 Jun; 33(2):128-36. doi: 10.1177/156482651203300206. [PMID: 22908694]
  • Monica N Orozco, Claudia Arriaga, Noel W Solomons, Klaus Schümann. Equivalent effects on fecal reactive oxygen species generation with oral supplementation of three iron compounds: ferrous sulfate, sodium iron EDTA and iron polymaltose. Annals of nutrition & metabolism. 2012; 60(2):108-14. doi: 10.1159/000336181. [PMID: 22414964]
  • Árpád Csog, Victor G Mihucz, Eniko Tatár, Ferenc Fodor, István Virág, Cornelia Majdik, Gyula Záray. Accumulation and distribution of iron, cadmium, lead and nickel in cucumber plants grown in hydroponics containing two different chelated iron supplies. Journal of plant physiology. 2011 Jul; 168(10):1038-44. doi: 10.1016/j.jplph.2010.12.014. [PMID: 21342715]
  • Barbara Troesch, Ines Egli, Christophe Zeder, Richard F Hurrell, Michael B Zimmermann. Fortification iron as ferrous sulfate plus ascorbic acid is more rapidly absorbed than as sodium iron EDTA but neither increases serum nontransferrin-bound iron in women. The Journal of nutrition. 2011 May; 141(5):822-7. doi: 10.3945/jn.110.136127. [PMID: 21430252]
  • Qiang Shi, Xiao-qian Yang, Xi Cui. The effects of FeCl₃ and Fe-EDTA on the development of psoriasis. Biological trace element research. 2011 Apr; 140(1):73-81. doi: 10.1007/s12011-010-8671-8. [PMID: 20352371]
  • Xiu X Han, Yong Y Sun, Ai G Ma, Fang Yang, Feng Z Zhang, Dian C Jiang, Yong Li. Moderate NaFeEDTA and ferrous sulfate supplementation can improve both hematologic status and oxidative stress in anemic pregnant women. Asia Pacific journal of clinical nutrition. 2011; 20(4):514-20. doi: NULL. [PMID: 22094835]
  • Maria Andersson, Winfried Theis, Michael B Zimmermann, Jasmin Tajeri Foman, Martin Jäkel, Guus S M J E Duchateau, Leon G J Frenken, Richard F Hurrell. Random serial sampling to evaluate efficacy of iron fortification: a randomized controlled trial of margarine fortification with ferric pyrophosphate or sodium iron edetate. The American journal of clinical nutrition. 2010 Nov; 92(5):1094-104. doi: 10.3945/ajcn.2010.29523. [PMID: 20844068]
  • Farzana Rahman, Ravi Naidu. The influence of arsenic speciation (AsIII & AsV) and concentration on the growth, uptake and translocation of arsenic in vegetable crops (silverbeet and amaranth): greenhouse study. Environmental geochemistry and health. 2009 Apr; 31 Suppl 1(?):115-24. doi: 10.1007/s10653-008-9241-2. [PMID: 19225721]
  • Hee-Seon Kim, Min-Kyoung Kim, Byung-Kook Lee. Oral supplementation with NaFeEDTA reduces blood lead in postmenopausal but not premenopausal Korean women with anemia. Nutrition (Burbank, Los Angeles County, Calif.). 2009 Jan; 25(1):66-71. doi: 10.1016/j.nut.2008.07.013. [PMID: 18834721]
  • Bo Wang, Siyan Zhan, Yinyin Xia, Liming Lee. Effect of sodium iron ethylenediaminetetra-acetate (NaFeEDTA) on haemoglobin and serum ferritin in iron-deficient populations: a systematic review and meta-analysis of randomised and quasi-randomised controlled trials. The British journal of nutrition. 2008 Dec; 100(6):1169-78. doi: 10.1017/s0007114508012208. [PMID: 18554425]
  • Bo Wang, Si-yan Zhan, Yin-yin Xia, Li-ming Li. [Effect of NaFeEDTA on serum ferritin level in iron deficient epidemic population: a systematic review]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 2008 Jun; 42(6):437-41. doi: NULL. [PMID: 19035048]
  • Martha E van Stuijvenberg, Cornelius M Smuts, Carl J Lombard, Muhammad A Dhansay. Fortifying brown bread with sodium iron EDTA, ferrous fumarate, or electrolytic iron does not affect iron status in South African schoolchildren. The Journal of nutrition. 2008 Apr; 138(4):782-6. doi: 10.1093/jn/138.4.782. [PMID: 18356335]
  • Philippe Longfils, Didier Monchy, Heike Weinheimer, Visith Chavasit, Yukiko Nakanishi, Klaus Schümann. A comparative intervention trial on fish sauce fortified with NaFe-EDTA and FeSO4+citrate in iron deficiency anemic school children in Kampot, Cambodia. Asia Pacific journal of clinical nutrition. 2008; 17(2):250-7. doi: . [PMID: 18586644]
  • Le Zhu, Dennis D Miller. Tissue iron distribution and urinary mineral excretion vary depending on the form of iron (FeSO4 or NaFeEDTA) and the route of administration (oral or subcutaneous) in rats given high doses of iron. Journal of agricultural and food chemistry. 2007 Oct; 55(21):8793-9. doi: 10.1021/jf0717135. [PMID: 17880165]
  • Pauline Ea Andang'o, Saskia Jm Osendarp, Rosemary Ayah, Clive E West, David L Mwaniki, Corine A De Wolf, Rob Kraaijenhagen, Frans J Kok, Hans Verhoef. Efficacy of iron-fortified whole maize flour on iron status of schoolchildren in Kenya: a randomised controlled trial. Lancet (London, England). 2007 May; 369(9575):1799-1806. doi: 10.1016/s0140-6736(07)60817-4. [PMID: 17531887]
  • Pankaj Sarkate, Amrapali Patil, Shashank Parulekar, N N Rege, B D Samant, Jaisen Lokhande, Ashwaria Gupta, Kamlakar Kulkarni. A randomised double-blind study comparing sodium feredetate with ferrous fumarate in anaemia in pregnancy. Journal of the Indian Medical Association. 2007 May; 105(5):278, 280-1, 284. doi: NULL. [PMID: 17915799]
  • Jun-Sheng Huo, Xiao-Guang Yang, Jian-Hua Piao, Jun-Quan Gao, Hong Miao, Bo Yu, Cheng-Qian Lu, Jun-Shi Chen. NaFeEDTA fortified soy sauce showed higher iron absorption rate in Chinese females. Biomedical and environmental sciences : BES. 2007 Apr; 20(2):126-30. doi: ". [PMID: 17624186]
  • Ana Alvarez-Fernández, Irene Orera, Javier Abadía, Anunciación Abadía. Determination of synthetic ferric chelates used as fertilizers by liquid chromatography-electrospray/mass spectrometry in agricultural matrices. Journal of the American Society for Mass Spectrometry. 2007 Jan; 18(1):37-47. doi: 10.1016/j.jasms.2006.08.018. [PMID: 17010641]
  • Jing Sun, Jian Huang, Wenxian Li, Lijuan Wang, Anxu Wang, Junsheng Huo, Junshi Chen, Chunming Chen. Effects of wheat flour fortified with different iron fortificants on iron status and anemia prevalence in iron deficient anemic students in Northern China. Asia Pacific journal of clinical nutrition. 2007; 16(1):116-21. doi: NULL. [PMID: 17215188]
  • Le Zhu, Chi Kong Yeung, Raymond P Glahn, Dennis D Miller. Iron dissociates from the NaFeEDTA complex prior to or during intestinal absorption in rats. Journal of agricultural and food chemistry. 2006 Oct; 54(20):7929-34. doi: 10.1021/jf0616964. [PMID: 17002472]
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  • Pham Van Thuy, Jacques Berger, Yukiko Nakanishi, Nguyen Cong Khan, Sean Lynch, Philip Dixon. The use of NaFeEDTA-fortified fish sauce is an effective tool for controlling iron deficiency in women of childbearing age in rural Vietnam. The Journal of nutrition. 2005 Nov; 135(11):2596-601. doi: 10.1093/jn/135.11.2596. [PMID: 16251617]
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