N-(4-aminobenzoyl)-L-glutamic acid (BioDeep_00000712081)

   


代谢物信息卡片


N-(4-aminobenzoyl)-L-glutamic acid

化学式: C12H14N2O5 (266.0902674)
中文名称: N-(4-氨基甲酰)-L-谷氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)N
InChI: InChI=1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1

描述信息

同义名列表

1 个代谢物同义名

N-(4-aminobenzoyl)-L-glutamic acid



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Michael R Duff, Scott A Gabel, Lars C Pedersen, Eugene F DeRose, Juno M Krahn, Elizabeth E Howell, Robert E London. The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase. Journal of medicinal chemistry. 2020 08; 63(15):8314-8324. doi: 10.1021/acs.jmedchem.0c00546. [PMID: 32658475]
  • Rama Kiblawi, Andreana N Holowatyj, Biljana Gigic, Stefanie Brezina, Anne J M R Geijsen, Jennifer Ose, Tengda Lin, Sheetal Hardikar, Caroline Himbert, Christy A Warby, Jürgen Böhm, Martijn J L Bours, Fränzel J B van Duijnhoven, Tanja Gumpenberger, Dieuwertje E Kok, Janna L Koole, Eline H van Roekel, Petra Schrotz-King, Arve Ulvik, Andrea Gsur, Nina Habermann, Matty P Weijenberg, Per Magne Ueland, Martin Schneider, Alexis Ulrich, Cornelia M Ulrich, Mary Playdon. One-carbon metabolites, B vitamins and associations with systemic inflammation and angiogenesis biomarkers among colorectal cancer patients: results from the ColoCare Study. The British journal of nutrition. 2020 05; 123(10):1187-1200. doi: 10.1017/s0007114520000422. [PMID: 32019627]
  • Katey L Witham, Neville J Butcher, Kim S Sugamori, Debbie Brenneman, Denis M Grant, Rodney F Minchin. 5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion. PloS one. 2013; 8(10):e77923. doi: 10.1371/journal.pone.0077923. [PMID: 24205029]
  • Barbara E Büttner, Veronica E Ohrvik, Peter Köhler, Cornelia M Witthöft, Michael Rychlik. Quantification of isotope-labeled and unlabeled folates and folate catabolites in urine samples by stable isotope dilution assay. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2013; 83(2):112-21. doi: 10.1024/0300-9831/a000152. [PMID: 24491884]
  • Susanna Kp Lau, Gilman Km Wong, Alan Kl Tsang, Jade Ll Teng, Rachel Yy Fan, Herman Tse, Kwok-Yung Yuen, Patrick Cy Woo. Virulence determinants, drug resistance and mobile genetic elements of Laribacter hongkongensis: a genome-wide analysis. Cell & bioscience. 2011 Apr; 1(1):17. doi: 10.1186/2045-3701-1-17. [PMID: 21711902]
  • B Álvarez-Sánchez, F Priego-Capote, J M Mata-Granados, M D Luque de Castro. Automated determination of folate catabolites in human biofluids (urine, breast milk and serum) by on-line SPE–HILIC–MS/MS. Journal of chromatography. A. 2010 Jul; 1217(28):4688-95. doi: 10.1016/j.chroma.2010.05.010. [PMID: 20605576]
  • Sabine Mönch, Michael Netzel, Gabriele Netzel, Michael Rychlik. Quantitation of folates and their catabolites in blood plasma, erythrocytes, and urine by stable isotope dilution assays. Analytical biochemistry. 2010 Mar; 398(2):150-60. doi: 10.1016/j.ab.2009.11.007. [PMID: 19903444]
  • Rita Hannisdal, Per Magne Ueland, Simone J P M Eussen, Asbjørn Svardal, Steinar Hustad. Analytical recovery of folate degradation products formed in human serum and plasma at room temperature. The Journal of nutrition. 2009 Jul; 139(7):1415-8. doi: 10.3945/jn.109.105635. [PMID: 19458027]
  • Rita Hannisdal, Per Magne Ueland, Asbjørn Svardal. Liquid chromatography-tandem mass spectrometry analysis of folate and folate catabolites in human serum. Clinical chemistry. 2009 Jun; 55(6):1147-54. doi: 10.1373/clinchem.2008.114389. [PMID: 19359539]
  • Hee-Ah Kim, Hyeon-Sook Lim. Dietary folate intake, blood folate status, and urinary folate catabolite excretion in Korean women of childbearing age. Journal of nutritional science and vitaminology. 2008 Aug; 54(4):291-7. doi: 10.3177/jnsv.54.291. [PMID: 18797150]
  • Rita Hannisdal, Asbjørn Svardal, Per Magne Ueland. Measurement of folate in fresh and archival serum samples as p-aminobenzoylglutamate equivalents. Clinical chemistry. 2008 Apr; 54(4):665-72. doi: 10.1373/clinchem.2007.100511. [PMID: 18281423]
  • Gale G Bozzo, Gilles J C Basset, Valeria Naponelli, Alexandre Noiriel, Jesse F Gregory, Andrew D Hanson. Characterization of the folate salvage enzyme p-aminobenzoylglutamate hydrolase in plants. Phytochemistry. 2008 Jan; 69(1):29-37. doi: 10.1016/j.phytochem.2007.06.031. [PMID: 17698154]
  • Isaac M Westwood, Edith Sim. Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa. BMC biochemistry. 2007 Mar; 8(?):3. doi: 10.1186/1471-2091-8-3. [PMID: 17374145]
  • Hee-Ah Kim, Jeong-Hwa Choi, Hyeon-Sook Lim. Childbearing women of twenty and under are at greater risk than those of twenty-five and over for compromised folate status. Nutrition research and practice. 2007; 1(4):254-9. doi: 10.4162/nrp.2007.1.4.254. [PMID: 20368947]
  • Giuseppe Orsomando, Gale G Bozzo, Rocío Díaz de la Garza, Gilles J Basset, Eoin P Quinlivan, Valeria Naponelli, Fabrice Rébeillé, Stéphane Ravanel, Jesse F Gregory, Andrew D Hanson. Evidence for folate-salvage reactions in plants. The Plant journal : for cell and molecular biology. 2006 May; 46(3):426-35. doi: 10.1111/j.1365-313x.2006.02685.x. [PMID: 16623903]
  • A A H Sokoro, M L Etter, J Lepage, B Weist, J Eichhorst, D C Lehotay. Simple method for the quantitative analysis of endogenous folate catabolites p-aminobenzoylglutamate (pABG) and its acetamido (apABG) derivative in human serum and urine by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2006 Feb; 832(1):9-16. doi: 10.1016/j.jchromb.2005.11.053. [PMID: 16427369]
  • Yumei Lin, Stephen R Dueker, Jennifer R Follett, James G Fadel, Ali Arjomand, Philip D Schneider, Joshua W Miller, Ralph Green, Bruce A Buchholz, John S Vogel, Robert D Phair, Andrew J Clifford. Quantitation of in vivo human folate metabolism. The American journal of clinical nutrition. 2004 Sep; 80(3):680-91. doi: 10.1093/ajcn/80.3.680. [PMID: 15321809]
  • Judith M Wolfe, Lynn B Bailey, Kelli Herrlinger-Garcia, Douglas W Theriaque, Jesse F Gregory, Gail P A Kauwell. Folate catabolite excretion is responsive to changes in dietary folate intake in elderly women. The American journal of clinical nutrition. 2003 Apr; 77(4):919-23. doi: 10.1093/ajcn/77.4.919. [PMID: 12663292]
  • Paul Michael Finglas, David Hart, Caroline Wolfe, Anthony John Aaron Wright, Sue Southon, Fred Mellon, Hanneke van den Akker, Kees de Meer. Validity of dual-label stable isotopic protocols and urinary excretion ratios to determine folate bioavailability from food. Food and nutrition bulletin. 2002 Sep; 23(3 Suppl):107-12. doi: 10.1177/15648265020233s121. [PMID: 12362776]
  • Marie A Caudill, Lynn B Bailey, Jesse F Gregory. Consumption of the folate breakdown product para-aminobenzoylglutamate contributes minimally to urinary folate catabolite excretion in humans: investigation using [(13)C(5)]para-aminobenzoylglutamate. The Journal of nutrition. 2002 Sep; 132(9):2613-6. doi: 10.1093/jn/132.9.2613. [PMID: 12221219]
  • J F Gregory, M A Caudill, F J Opalko, L B Bailey. Kinetics of folate turnover in pregnant women (second trimester) and nonpregnant controls during folic acid supplementation: stable-isotopic labeling of plasma folate, urinary folate and folate catabolites shows subtle effects of pregnancy on turnover of folate pools. The Journal of nutrition. 2001 Jul; 131(7):1928-37. doi: 10.1093/jn/131.7.1928. [PMID: 11435509]
  • J F Gregory, M E Swendseid, R A Jacob. Urinary excretion of folate catabolites responds to changes in folate intake more slowly than plasma folate and homocysteine concentrations and lymphocyte DNA methylation in postmenopausal women. The Journal of nutrition. 2000 Dec; 130(12):2949-52. doi: 10.1093/jn/130.12.2949. [PMID: 11110852]
  • J R Higgins, E P Quinlivan, J McPartlin, J M Scott, D G Weir, M R Darling. The relationship between increased folate catabolism and the increased requirement for folate in pregnancy. BJOG : an international journal of obstetrics and gynaecology. 2000 Sep; 107(9):1149-54. doi: 10.1111/j.1471-0528.2000.tb11115.x. [PMID: 11002960]
  • J F Gregory, J Williamson, J F Liao, L B Bailey, J P Toth. Kinetic model of folate metabolism in nonpregnant women consuming [2H2]folic acid: isotopic labeling of urinary folate and the catabolite para-acetamidobenzoylglutamate indicates slow, intake-dependent, turnover of folate pools. The Journal of nutrition. 1998 Nov; 128(11):1896-906. doi: 10.1093/jn/128.11.1896. [PMID: 9808640]
  • M A Caudill, J F Gregory, A D Hutson, L B Bailey. Folate catabolism in pregnant and nonpregnant women with controlled folate intakes. The Journal of nutrition. 1998 Feb; 128(2):204-8. doi: 10.1093/jn/128.2.204. [PMID: 9446844]
  • J McPartlin, J Scott. Identification and assay of folate catabolites in human urine. Methods in enzymology. 1997; 281(?):70-7. doi: 10.1016/s0076-6879(97)81010-5. [PMID: 9250968]
  • P A Kownacki-Brown, C Wang, L B Bailey, J P Toth, J F Gregory. Urinary excretion of deuterium-labeled folate and the metabolite p-aminobenzoylglutamate in humans. The Journal of nutrition. 1993 Jun; 123(6):1101-8. doi: 10.1093/jn/123.6.1101. [PMID: 8505671]
  • H McNulty, J McPartlin, D Weir, J Scott. Reversed-phase high-performance liquid chromatographic method for the quantitation of endogenous folate catabolites in rat urine. Journal of chromatography. 1993 Apr; 614(1):59-66. doi: 10.1016/0378-4347(93)80223-q. [PMID: 8496286]
  • J McPartlin, A Halligan, J M Scott, M Darling, D G Weir. Accelerated folate breakdown in pregnancy. Lancet (London, England). 1993 Jan; 341(8838):148-9. doi: 10.1016/0140-6736(93)90007-4. [PMID: 8093747]
  • H McNulty, J M McPartlin, D G Weir, J M Scott. Folate catabolism in normal subjects. Human nutrition. Applied nutrition. 1987 Oct; 41(5):338-41. doi: NULL. [PMID: 3692900]
  • D Kelly, B Reed, D Weir, J Scott. Effect of acute and chronic alcohol ingestion on the rate of folate catabolism and hepatic enzyme induction in mice. Clinical science (London, England : 1979). 1981 Feb; 60(2):221-4. doi: 10.1042/cs0600221. [PMID: 6786816]