Oxendolone (BioDeep_00000710755)
代谢物信息卡片
化学式: C20H30O2 (302.2246)
中文名称: 奥生多龙
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1CC2C3CCC4=CC(=O)CCC4C3CCC2(C1O)C
InChI: InChI=1S/C20H30O2/c1-3-12-11-18-17-6-4-13-10-14(21)5-7-15(13)16(17)8-9-20(18,2)19(12)22/h10,12,15-19,22H,3-9,11H2,1-2H3/t12-,15-,16+,17+,18-,19-,20-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C242 - Anti-Androgen
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:31946
- KEGGdrug: D01329
- PubChem: 443947
- ChEMBL: CHEMBL513856
- CAS: 33765-68-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- O Shirota, K Takizawa, S Sekita, M Satake, Y Hirayama, Y Hakamata, T Hayashi, T Yanagawa. Antiandrogenic natural Diels--Alder-type adducts from Brosimum rubescens.
Journal of natural products.
1997 Oct; 60(10):997-1002. doi:
10.1021/np9607215
. [PMID: 9358642] - K Yamada, H Komatsu, A Ohta. Effects of 3,6-dimethylpyrazine-2-thiol on reproductive and accessory reproductive organs in male rats.
Biological & pharmaceutical bulletin.
1996 Mar; 19(3):360-3. doi:
10.1248/bpb.19.360
. [PMID: 8924900] - H Iguchi, T Ikeuchi, Y Kai, H Yoshida. [Influence of anti-androgen therapy for prostatic hypertrophy on lipid metabolism].
Hinyokika kiyo. Acta urologica Japonica.
1994 Mar; 40(3):215-9. doi:
NULL
. [PMID: 7513937] - T Suzuki, I Horibe, N Uchida, K Ezumi, K Uchida, K Takeda, A Tanaka, Y Nishizawa, K Matsumoto. Effects of antiandrogens on growth of androgen-dependent mouse mammary tumor (Shionogi carcinoma 115) in vivo and in vitro.
The Journal of steroid biochemistry and molecular biology.
1990 Nov; 37(4):559-67. doi:
10.1016/0960-0760(90)90401-6
. [PMID: 2278840] - P Ostri, R Swartz, H H Meyhoff, J H Petersen, G Lindgård, C Frimodt-Møller, T Andersson, M S Nielsen. Antiandrogenic treatment of benign prostatic hyperplasia: a placebo controlled trial.
Urological research.
1989; 17(1):29-33. doi:
10.1007/bf00261046
. [PMID: 2466359] - Y Kumamoto, T Tsukamoto, Y Takagi, S Furuya, E Yokoyama, K Takatsuka, T Tamiya, S Miyamoto, T Aoyama, A Honma. [Clinical efficacy of oxendolene (antiandrogen) and bunazosin hydrochloride (alpha-adrenergic blocker) in the treatment of prostatism--comparative study of oxendolone, bunazocin hydrochloride and their combination].
Hinyokika kiyo. Acta urologica Japonica.
1987 Nov; 33(11):1921-41. doi:
NULL
. [PMID: 2451412] - K Sudo, M Masuoka, K Hiraga, K Yoshida, R Nakayama. Radioimmunoassay for serum levels of an anti-androgen TSAA-291 (Oxendolone) in rats.
Journal of pharmacobio-dynamics.
1984 Jun; 7(6):378-84. doi:
10.1248/bpb1978.7.378
. [PMID: 6481613] - A Yasukawa, H Nihira, S Matsuki, M Fujii, H Fujiwara, T Kitano, M Kodama, R Ukai, O Tado, K Sagami. [Clinical experience with oxendolone for treatment of benign prostatic hyperplasia. Clinical efficacy and effects on serum lipid and lipoprotein fraction levels].
Hinyokika kiyo. Acta urologica Japonica.
1984 Apr; 30(4):537-43. doi:
NULL
. [PMID: 6207714] - I Midgley, A G Fowkes, A Darragh, R Lambe, L F Chasseaud, T Taylor. The metabolic fate of the anti-androgenic agent, oxendolone, in man.
Steroids.
1983 Apr; 41(4):521-36. doi:
10.1016/0039-128x(83)90092-2
. [PMID: 6419414] - K Sudo, K Yoshida, Y Akinaga, R Nakayama. 5alpha-reduction of an anti-androgen TSAA-291, 16beta-ethyl-17beta-hydroxy-4-estren-3-one, by nuclear 5alpha-reductase in rat prostates.
Steroids.
1981 Jul; 38(1):55-71. doi:
10.1016/0039-128x(81)90021-0
. [PMID: 7292540] - S Tanayama, K Yoshida, T Kondo, Y Kanai. Disposition and metabolism of 16 beta-ethyl-17 beta-hydroxy-4-estern-3-one (TSAA-291), a new antiandrogen, in rats.
Steroids.
1979 Jan; 33(1):65-83. doi:
10.1016/s0039-128x(79)80007-0
. [PMID: 452062]