N-(4-Nitrophenyl)-L-glutamine (BioDeep_00000709859)
代谢物信息卡片
(S)-2-Amino-5-((4-nitrophenyl)amino)-5-oxopentanoic acid
化学式: C11H13N3O5 (267.0855168)
中文名称: L-γ-谷氨酰对硝基苯胺一水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1NC(=O)CCC(C(=O)O)N)[N+](=O)[O-]
InChI: InChI=1S/C11H13N3O5/c12-9(11(16)17)5-6-10(15)13-7-1-3-8(4-2-7)14(18)19/h1-4,9H,5-6,12H2,(H,13,15)(H,16,17)/t9-/m0/s1
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Monika K Prelowska, Dawid Mehlich, M Talha Ugurlu, Hanna Kedzierska, Aleksandra Cwiek, Artur Kosnik, Klaudia Kaminska, Anna A Marusiak, Dominika Nowis. Inhibition of the ʟ-glutamine transporter ASCT2 sensitizes plasma cell myeloma cells to proteasome inhibitors.
Cancer letters.
2021 06; 507(?):13-25. doi:
10.1016/j.canlet.2021.02.020. [PMID: 33713737] - Anita A Agblor, P David Josephy. Donor substrate specificity of bovine kidney gamma-glutamyltransferase.
Chemico-biological interactions.
2013 Apr; 203(2):480-5. doi:
10.1016/j.cbi.2013.02.007. [PMID: 23500672] - Christian Lherbet, Mylène Morin, Roselyne Castonguay, Jeffrey W Keillor. Synthesis of aza and oxaglutamyl-p-nitroanilide derivatives and their kinetic studies with gamma-glutamyltranspeptidase.
Bioorganic & medicinal chemistry letters.
2003 Mar; 13(6):997-1000. doi:
10.1016/s0960-894x(03)00083-0. [PMID: 12643897] - Lisa Connolly, Terence L Fodey, Steven R H Crooks, Philippe Delahaut, Christopher T Elliott. The production and characterisation of dinitrocarbanilide antibodies raised using antigen mimics.
Journal of immunological methods.
2002 Jun; 264(1-2):45-51. doi:
10.1016/s0022-1759(02)00040-6. [PMID: 12191508] - A Ménard, R Castonguay, C Lherbet, C Rivard, Y Roupioz, J W Keillor. Nonlinear free energy relationship in the general-acid-catalyzed acylation of rat kidney gamma-glutamyl transpeptidase by a series of gamma-glutamyl anilide substrate analogues.
Biochemistry.
2001 Oct; 40(42):12678-85. doi:
10.1021/bi011234d. [PMID: 11601992] - S Finney, L Seale, R T Sawyer, R B Wallis. Tridegin, a new peptidic inhibitor of factor XIIIa, from the blood-sucking leech Haementeria ghilianii.
The Biochemical journal.
1997 Jun; 324 ( Pt 3)(?):797-805. doi:
10.1042/bj3240797. [PMID: 9210403] - L Dvoráková, J Krůsek, F Stastný, V Lisý. Analysis of kinetic properties of gamma-glutamyl transpeptidase from rat kidney.
General physiology and biophysics.
1996 Oct; 15(5):403-13. doi:
NULL. [PMID: 9228521] - Gololobov MYu, R C Bateman. gamma-Glutamyltranspeptidase-catalysed acyl-transfer to the added acceptor does not proceed via the ping-pong mechanism.
The Biochemical journal.
1994 Dec; 304 ( Pt 3)(?):869-76. doi:
10.1042/bj3040869. [PMID: 7818493] - P C Nicholas, D L Thomas. The measurement of gamma-glutamyl transferase activity in sheep liver, kidney and pancreas with oxidized glutathione. A comparison with the activities found using gamma-glutamyl p-nitroanilide in the absence and presence of glycylglycine.
Biochemical Society transactions.
1991 Feb; 19(1):49S. doi:
10.1042/bst019049s. [PMID: 1674705] - P C Nicholas, D L Thomas. The reaction of oxidized and reduced glutathione (with some amino-acids) and L-gamma-glutamyl p-nitroanilide with sheep kidney tissue homogenate. An examination of the reaction products by paper chromatography.
Biochemical Society transactions.
1991 Feb; 19(1):50S. doi:
10.1042/bst019050s. [PMID: 1674706] - P M Verhoeff, F P Peters, H Steigstra, J C Hafkenscheid. Behaviour of L-gamma-glutamyl-4-nitroanilide and L-gamma-glutamyl-3-carboxy-4-nitroanilide with respect to gamma-glutamyltransferases of different origin.
Clinica chimica acta; international journal of clinical chemistry.
1988 Jul; 175(2):129-34. doi:
10.1016/0009-8981(88)90002-2. [PMID: 2900705] - D Aharony, P Dobson. Discriminative effect of gamma-glutamyl transpeptidase inhibitors on metabolism of leukotriene C4 in peritoneal cells.
Life sciences.
1984 Nov; 35(21):2135-42. doi:
10.1016/0024-3205(84)90513-7. [PMID: 6149445] - J Igari, K Tauchi. [Methods of serum enzyme determination and its clinical significance: gamma-glutamyl transpeptidase].
Rinsho byori. The Japanese journal of clinical pathology.
1983 Jun; Suppl 55(?):101-14. doi:
NULL. [PMID: 6140319] - W A Abbott, A Meister. Modulation of gamma-glutamyl transpeptidase activity by bile acids.
The Journal of biological chemistry.
1983 May; 258(10):6193-7. doi:
NULL. [PMID: 6133860] - D Toya, N Sawabu, K Ozaki, T Wakabayashi, M Nakagen, N Hattori. Purification of gamma-glutamyltranspeptidase (gamma-GTP) from human hepatocellular carcinoma (HCC), and comparison of gamma-GTP with the enzyme from human kidney.
Annals of the New York Academy of Sciences.
1983; 417(?):86-96. doi:
10.1111/j.1749-6632.1983.tb32852.x. [PMID: 6142676] - D Thornley-Brown, P D Dass, T C Welbourne. Acetazolamide inhibition of renal gamma-glutamyl transpeptidase.
Biochemical pharmacology.
1982 Nov; 31(21):3347-52. doi:
10.1016/0006-2952(82)90610-4. [PMID: 6128982] - P Selvaraj, K A Balasubramanian. Localization of gamma-glutamyl transferase on polyacrylamide gels using L-gamma-glutamyl-p-nitroanilide as substrate.
Clinica chimica acta; international journal of clinical chemistry.
1982 Jun; 121(3):291-300. doi:
10.1016/0009-8981(82)90238-8. [PMID: 6179655] - F Schiele, Y Artur, D Bagrel, C Petitclerc, G Siest. Measurement of plasma gamma-glutamyltransferase in clinical chemistry: kinetic basis and standardisation propositions.
Clinica chimica acta; international journal of clinical chemistry.
1981 May; 112(2):187-95. doi:
10.1016/0009-8981(81)90377-6. [PMID: 6113067] - T C Welbourne, P D Dass. Mechanism of the acidosis induced adaptation in renal gamma-glutamyltransferase.
Life sciences.
1981 Mar; 28(11):1219-24. doi:
10.1016/0024-3205(81)90447-1. [PMID: 6112650] - P D Dass, T C Welbourne. Evidence for lumenal and antilumenal localization of gamma-glutamyltranspeptidase in rat kidney.
Life sciences.
1981 Jan; 28(4):355-60. doi:
10.1016/0024-3205(81)90079-5. [PMID: 6111728] - L M Allen, M V Corrigan, T Meinking. Interaction of AT-125, (alpha S,5S)-amino-3-chloro-4,5-dihydroisoxazoleacetic acid, with bovine kidney gamma-glutamyl transpeptidase.
Chemico-biological interactions.
1981 Jan; 33(2-3):361-5. doi:
10.1016/0009-2797(81)90053-3. [PMID: 6109574]