Methylprednisolone aceponate (BioDeep_00000709586)
代谢物信息卡片
化学式: C27H36O7 (472.2460906)
中文名称: 甲基泼尼松龙乙丙酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(=O)OC1(CCC2C1(CC(C3C2CC(C4=CC(=O)C=CC34C)C)O)C)C(=O)COC(=O)C
InChI: InChI=1S/C27H36O7/c1-6-23(32)34-27(22(31)14-33-16(3)28)10-8-19-18-11-15(2)20-12-17(29)7-9-25(20,4)24(18)21(30)13-26(19,27)5/h7,9,12,15,18-19,21,24,30H,6,8,10-11,13-14H2,1-5H3/t15-,18-,19-,21-,24+,25-,26-,27-/m0/s1
描述信息
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii)
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D000893 - Anti-Inflammatory Agents
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:135762
- KEGGdrug: D07203
- PubChem: 63019
- DrugBank: DB14643
- ChEMBL: CHEMBL1697782
- CAS: 86401-95-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Elvira Escribano-Ferrer, Josep Queralt Regué, Xavier Garcia-Sala, Antoni Boix Montañés, Rosa M Lamuela-Raventos. In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.
Journal of natural products.
2019 02; 82(2):177-182. doi:
10.1021/acs.jnatprod.8b00366
. [PMID: 30688453] - Na Young Yoon, Min young Jung, Dong Hye Kim, Hae Jin Lee, Eung Ho Choi. Topical glucocorticoid or pimecrolimus treatment suppresses thymic stromal lymphopoietin-related allergic inflammatory mechanism in an oxazolone-induced atopic dermatitis murine model.
Archives of dermatological research.
2015 Sep; 307(7):569-81. doi:
10.1007/s00403-015-1558-y
. [PMID: 25786383] - S Veraldi, E Cuka, C Francia, M C Persico. Scabies acquired in Chinese massage centers.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia.
2014 Oct; 149(5):627-8. doi:
"
. [PMID: 25213389] - Razvigor Darlenski, Jana Kazandjieva, Nikolai Tsankov. Phytodermatitis to Euphorbia trigona.
Skinmed.
2014 Jul; 12(4):253-5. doi:
"
. [PMID: 25335357] - D Carati, M Guido, A Malvasi, A Zizza, A Tinelli. Efficacy of a Dermoxen® lenitiva for pruritus genitalis in a randomized, double blind trial.
European review for medical and pharmacological sciences.
2013 Oct; 17(19):2668-74. doi:
"
. [PMID: 24142616] - Cezar-Doru Radu, Mihaela Salariu, Manuela Avadanei, Cristina Ghiciuc, Lili Foia, Elena Cătălina Lupusoru, Ada Ferri, Eugen Ulea, Florin Lipsa. Cotton-made cellulose support for anti-allergic pajamas.
Carbohydrate polymers.
2013 Jun; 95(1):479-86. doi:
10.1016/j.carbpol.2013.03.037
. [PMID: 23618296] - A Ramírez-Bosca, P Zapater, I Betlloch, F Albero, A Martínez, J Díaz-Alperi, J F Horga. Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial.
Actas dermo-sifiliograficas.
2012 Sep; 103(7):599-607. doi:
10.1016/j.ad.2012.01.008
. [PMID: 22560125] - Young Bok Lee, Hyun Jung Park, Mi Jung Kwon, Se Kyoo Jeong, Sang Hyun Cho. Beneficial effects of pseudoceramide-containing physiologic lipid mixture as a vehicle for topical steroids.
European journal of dermatology : EJD.
2011 Sep; 21(5):710-6. doi:
10.1684/ejd.2011.1447
. [PMID: 21708519] - U Blume-Peytavi, U Wahn. Optimizing the treatment of atopic dermatitis in children: a review of the benefit/risk ratio of methylprednisolone aceponate.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2011 May; 25(5):508-15. doi:
10.1111/j.1468-3083.2010.03942.x
. [PMID: 21492244] - V H Koliadenko, P V Chernyshov. [Interleukin-6 as a marker of the activity of a pathological process in patients with psoriasis].
Likars'ka sprava.
2005 Jul; ?(5-6):80-2. doi:
NULL
. [PMID: 16396302] - Jennifer Cahill, Rosemary Nixon. Allergic contact dermatitis to methylprednisolone aceponate in a topical corticosteroid.
The Australasian journal of dermatology.
2004 Aug; 45(3):192-3. doi:
10.1111/j.1440-0960.2004.00089.x
. [PMID: 15250903] - C Günther, A Kecskes, T Staks, U Täuber. Percutaneous absorption of methylprednisolone aceponate following topical application of Advantan lotion on intact, inflamed and stripped skin of male volunteers.
Skin pharmacology and applied skin physiology.
1998 Jan; 11(1):35-42. doi:
10.1159/000029806
. [PMID: 9603667] - A Kecskés, D Heger-Mahn, R K Kuhlmann, L Lange. Comparison of the local and systemic side effects of methylprednisolone aceponate and mometasone furoate applied as ointments with equal antiinflammatory activity.
Journal of the American Academy of Dermatology.
1993 Oct; 29(4):576-80. doi:
10.1016/0190-9622(93)70224-h
. [PMID: 8408793] - A Kecskés, P Jahn, H Matthes, R K Kuhlmann, L Lange. Systemic effects of topically applied methylprednisolone aceponate in healthy volunteers.
Journal of the American Academy of Dermatology.
1993 May; 28(5 Pt 1):789-92. doi:
10.1016/s0190-9622(09)80276-4
. [PMID: 8496431] - U Täuber, H Matthes. Percutaneous absorption of methylprednisolone aceponate after single and multiple dermal application as ointment in male volunteers.
Arzneimittel-Forschung.
1992 Sep; 42(9):1122-4. doi:
NULL
. [PMID: 1445479]