Technetium (BioDeep_00000708674)
代谢物信息卡片
technetium atom
化学式: Tc (98)
中文名称: 锝
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: [Tc]
InChI: InChI=1S/Tc
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Mariella Terán, Jessica Osorio, Elena Cardoso, Emilia Tejería, Andrea Paolino, Ana Laura Reyes, Gianna Cecchetto. [99m Tc]Tc-HYNIC-EcgDf21: A defensin short analogue with potential application in infection foci imaging.
Chemical biology & drug design.
2023 03; 101(3):593-604. doi:
10.1111/cbdd.14149. [PMID: 36138520] - Xinyu Wang, Peng Xu, Yuying Jiao, Sha Luan, Yue Gao, Changjiu Zhao, Peng Fu. Preliminary evaluation of a small interfering RNA molecular probe targeting murine double minute 2 in breast cancer.
Nuclear medicine communications.
2022 Aug; 43(8):869-876. doi:
10.1097/mnm.0000000000001582. [PMID: 35582848] - Atena Najdian, Massoud Amanlou, Davood Beiki, Ahmad Bitarafan-Rajabi, Mehdi Mirzaei, Mehdi Shafiee Ardestani. Amino-modified-silica-coated gadolinium-copper nanoclusters, conjugated to AS1411 aptamer and radiolabeled with technetium-99 m as a novel multimodal imaging agent.
Bioorganic chemistry.
2022 08; 125(?):105827. doi:
10.1016/j.bioorg.2022.105827. [PMID: 35569188] - James Warwick, Jennifer Holness. Measurement of Glomerular Filtration Rate.
Seminars in nuclear medicine.
2022 07; 52(4):453-466. doi:
10.1053/j.semnuclmed.2021.12.005. [PMID: 35063168] - Hamidreza Ghorbani, Salman Soltani, Seyed Rasoul Zakavi, Alireza Masoudifard, Reihaneh Aryan, Mahdi Mottaghi, Kamran Aryana, Atena Aghaee. Bone scan with technetium 99m-methyl diphosphonate, the missing link in the initial staging of muscle-invasive bladder carcinoma.
Nuclear medicine communications.
2022 Jun; 43(6):675-679. doi:
10.1097/mnm.0000000000001559. [PMID: 35414637] - Beatriz Lasa-Saracíbar, Souhaila H El Moukhtari, Theodoros Tsotakos, Stavros Xanthopoulos, George Loudos, Penelope Bouziotis, Maria J Blanco-Prieto. In vivo biodistribution of edelfosine-loaded lipid nanoparticles radiolabeled with Technetium-99 m: Comparison of administration routes in mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2022 Jun; 175(?):1-6. doi:
10.1016/j.ejpb.2022.04.007. [PMID: 35462025] - Pavithra H A Kankanamalage, Rebecca Hoerres, Khanh-Van Ho, Carolyn J Anderson, Fabio Gallazzi, Heather M Hennkens. p-NCS-Bn-NODAGA as a bifunctional chelator for radiolabeling with the 186Re/99mTc-tricarbonyl core: Radiochemistry with model complexes and a GRPR-targeting peptide.
Nuclear medicine and biology.
2022 May; 108-109(?):1-9. doi:
10.1016/j.nucmedbio.2022.01.004. [PMID: 35144046] - Qing Ruan, Junhong Feng, Yuhao Jiang, Xuran Zhang, Xiaojiang Duan, Qianna Wang, Guangxing Yin, Di Xiao, Junbo Zhang. Preparation and Bioevaluation of 99mTc-Labeled FAP Inhibitors as Tumor Radiotracers to Target the Fibroblast Activation Protein.
Molecular pharmaceutics.
2022 01; 19(1):160-171. doi:
10.1021/acs.molpharmaceut.1c00712. [PMID: 34904839] - Liam Widjaja, Thorsten Derlin, Tobias L Ross, Frank M Bengel, Rudolf A Werner. Pretherapeutic estimated glomerular filtration rate predicts development of chronic kidney disease in patients receiving PSMA-targeted radioligand therapy.
The Prostate.
2022 01; 82(1):86-96. doi:
10.1002/pros.24250. [PMID: 34633090] - Diana Trujillo-Benítez, Myrna Luna-Gutiérrez, Guillermina Ferro-Flores, Blanca Ocampo-García, Clara Santos-Cuevas, Gerardo Bravo-Villegas, Enrique Morales-Ávila, Pedro Cruz-Nova, Lorenza Díaz-Nieto, Janice García-Quiroz, Erika Azorín-Vega, Antonio Rosato, Laura Meléndez-Alafort. Design, Synthesis and Preclinical Assessment of 99mTc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging.
Molecules (Basel, Switzerland).
2022 Jan; 27(1):. doi:
10.3390/molecules27010264. [PMID: 35011496] - Yuying Jiao, Peng Xu, Sha Luan, Xinyu Wang, Yue Gao, Changjiu Zhao, Peng Fu. Molecular imaging and treatment of PSMA-positive prostate cancer with 99mTc radiolabeled aptamer-siRNA chimeras.
Nuclear medicine and biology.
2022 Jan; 104-105(?):28-37. doi:
10.1016/j.nucmedbio.2021.11.003. [PMID: 34847481] - Shimpei Iikuni, Anna Kitano, Hiroyuki Watanabe, Masahiro Ono. Feasibility of using a 99mTc-hydroxamamide complex containing an albumin binder moiety for in vivo albumin labeling-based tumor imaging.
Bioorganic & medicinal chemistry letters.
2021 12; 53(?):128417. doi:
10.1016/j.bmcl.2021.128417. [PMID: 34710623] - Ann Mai Østergaard, Stine S Langaa, Marie H Vrist, Frank H Mose, Jesper N Bech, Claire A Fynbo, Jørn Theil, June A Ejlersen. Technetium-99m-MAG3 and technetium-99m-DTPA: Renal clearance measured by the constant infusion technique - Old news?.
Clinical physiology and functional imaging.
2021 Nov; 41(6):488-496. doi:
10.1111/cpf.12724. [PMID: 34418886] - Selçuk Varol, Faruk Öktem, Abdurrahim Koçyiğit, Ayşegül Doğan Demir, Ersin Karataş, Mehmet Aydın, Nilüfer Göknar, Tümay İpekçi. The impact of Technetium-99m dimercapto-succinic acid scintigraphy on DNA damage and oxidative stress in children.
International journal of clinical practice.
2021 Nov; 75(11):e14810. doi:
10.1111/ijcp.14810. [PMID: 34487588] - Nourihan S Farrag, Amro Shetta, Wael Mamdouh. Green tea essential oil encapsulated chitosan nanoparticles-based radiopharmaceutical as a new trend for solid tumor theranosis.
International journal of biological macromolecules.
2021 Sep; 186(?):811-819. doi:
10.1016/j.ijbiomac.2021.07.077. [PMID: 34280444] - Junhong Feng, Xuran Zhang, Qing Ruan, Yuhao Jiang, Junbo Zhang. Preparation and Evaluation of Novel Folate Isonitrile 99mTc Complexes as Potential Tumor Imaging Agents to Target Folate Receptors.
Molecules (Basel, Switzerland).
2021 Jul; 26(15):. doi:
10.3390/molecules26154552. [PMID: 34361705] - Nicola Beindorff, Fabian Schmitz-Peiffer, Daniel Messroghli, Winfried Brenner, Janet F Eary. Radionuclide, magnetic resonance and computed tomography imaging in European round back slugs (Arionidae) and leopard slugs (Limacidae).
Scientific reports.
2021 07; 11(1):13798. doi:
10.1038/s41598-021-93012-2. [PMID: 34226574] - Zhuo T Su, Hiten D Patel, Mitchell M Huang, Alexa R Meyer, Christian P Pavlovich, Phillip M Pierorazio, Mehrbod S Javadi, Mohamad E Allaf, Steven P Rowe, Michael A Gorin. Cost-effectiveness Analysis of 99mTc-sestamibi SPECT/CT to Guide Management of Small Renal Masses.
European urology focus.
2021 Jul; 7(4):827-834. doi:
10.1016/j.euf.2020.02.010. [PMID: 32115400] - Emmanuelle Vidal-Petiot, Marie Courbebaisse, Marine Livrozet, Gwénaëlle Corrégé, Timofei Rusu, Françoise Montravers, Stéphanie Baron, Léa Dupont, Clara Balouzet, Corinne Smadja, Sébastien Leygnac, Guillaume Pariscoat, Jimmy Rose, François Rouzet, Pascal Houillier, Jean-Philippe Haymann, Martin Flamant. Comparison of 51Cr-EDTA and 99mTc-DTPA for glomerular filtration rate measurement.
Journal of nephrology.
2021 06; 34(3):729-737. doi:
10.1007/s40620-020-00932-9. [PMID: 33661505] - Dongjian Zhang, Qiaomei Jin, Meng Gao, Cuihua Jiang, Yicheng Ni, Jian Zhang. Untiring Pursuit for Glucarate-Based Molecular Imaging Probes.
Molecular imaging and biology.
2021 06; 23(3):310-322. doi:
10.1007/s11307-020-01564-y. [PMID: 33206335] - Neelam Kumari, Ankur Kaul, Raunak Varshney, Vinay Kumar Singh, Krishna Srivastava, Sunita Bhagat, Anil Kumar Mishra, Anjani Kumar Tiwari. Synthesis and evaluation of technetium-99m labelled 1-(2-methoxyphenyl)piperazine derivative for single photon emission computed tomography imaging for targeting 5-HT1A.
Bioorganic chemistry.
2021 06; 111(?):104972. doi:
10.1016/j.bioorg.2021.104972. [PMID: 33993020] - Qiong Fu, Ping Feng, Ling-Yun Sun, Xiao-Xia Zuo, Dong-Bao Zhao, Dong-Yi He, Hua-Xiang Wu, Wei Zhang, Wei Zhang, Fang Du, Chun-De Bao. A double-blind, double-dummy, randomized controlled, multicenter trial of 99Tc-methylene diphosphonate in patients with moderate to severe rheumatoid arthritis.
Chinese medical journal.
2021 May; 134(12):1457-1464. doi:
10.1097/cm9.0000000000001527. [PMID: 34039871] - Ifra Sanaullah, M Imran, Saira Riaz, Tabassum Amin, Irfan Ullah Khan, Rizwana Zahoor, Abubaker Shahid, Shahzad Naseem. Microwave assisted synthesis of Fe3O4 stabilized ZrO2 nanoparticles - Free radical scavenging, radiolabeling and biodistribution in rabbits.
Life sciences.
2021 Apr; 271(?):119070. doi:
10.1016/j.lfs.2021.119070. [PMID: 33465388] - Olga Bragina, Emma von Witting, Javad Garousi, Roman Zelchan, Mattias Sandström, Anna Orlova, Anna Medvedeva, Artem Doroshenko, Anzhelika Vorobyeva, Sarah Lindbo, Jesper Borin, Natalya Tarabanovskaya, Jens Sörensen, Sophia Hober, Vladimir Chernov, Vladimir Tolmachev. Phase I Study of 99mTc-ADAPT6, a Scaffold Protein-Based Probe for Visualization of HER2 Expression in Breast Cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2021 04; 62(4):493-499. doi:
10.2967/jnumed.120.248799. [PMID: 32817142] - Maryam Mazaheri Tehrani, Mostafa Erfani, Nour Amirmozafari. [99m Tc-HYNIC/EDDA]-MccJ25 antimicrobial peptide analog as a potential radiotracer for detection of infection.
Chemical biology & drug design.
2021 04; 97(4):904-913. doi:
10.1111/cbdd.13817. [PMID: 33326679] - Mirel Cabrera, Nicole Lecot, Marcelo Fernández, J P Gambini, Williams Porcal, Pablo Cabral. 99mTc Stearyl 6-(benzylidenehydrazinyl) nicotinamide Liposomes as Tumor Permeability Evaluation Tracer.
AAPS PharmSciTech.
2021 Mar; 22(3):115. doi:
10.1208/s12249-021-01984-1. [PMID: 33763814] - Maryam Oroujeni, Sara S Rinne, Anzhelika Vorobyeva, Annika Loftenius, Joachim Feldwisch, Per Jonasson, Vladimir Chernov, Anna Orlova, Fredrik Y Frejd, Vladimir Tolmachev. Preclinical Evaluation of 99mTc-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake.
International journal of molecular sciences.
2021 Mar; 22(5):. doi:
10.3390/ijms22052770. [PMID: 33803361] - Sveva Auletta, Filippo Galli, Michela Varani, Giuseppe Campagna, Martina Conserva, Daniela Martinelli, Iolanda Santino, Alberto Signore. In Vitro and In Vivo Evaluation of 99mTc-Polymyxin B for Specific Targeting of Gram-Bacteria.
Biomolecules.
2021 02; 11(2):. doi:
10.3390/biom11020232. [PMID: 33562877] - Jayesh A Dhanani, Steven Goodman, Benjamin Ahern, Jeremy Cohen, John F Fraser, Adrian Barnett, Sara Diab, Manoj Bhatt, Jason A Roberts. Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study.
International journal of antimicrobial agents.
2021 Feb; 57(2):106232. doi:
10.1016/j.ijantimicag.2020.106232. [PMID: 33232733] - George Makris, Rajendra P Bandari, Marina Kuchuk, Silvia S Jurisson, Charles J Smith, Heather M Hennkens. Development and Preclinical Evaluation of 99mTc- and 186Re-Labeled NOTA and NODAGA Bioconjugates Demonstrating Matched Pair Targeting of GRPR-Expressing Tumors.
Molecular imaging and biology.
2021 02; 23(1):52-61. doi:
10.1007/s11307-020-01537-1. [PMID: 32886303] - Dawei Jiang, Muhsin H Younis, Xiaoli Lan, Weibo Cai. High-performance renal imaging with a radiolabeled, non-excretable chimeric fusion protein.
Theranostics.
2021; 11(18):9177-9179. doi:
10.7150/thno.66417. [PMID: 34522233] - Xiaoyan Duan, Yiri Du, Chunmei Wang, Zhenfeng Zhao, Chao Li, Jianbo Li. Radiolabeling and Preliminary Evaluation of 99mTc-Labeled DNA Cube Nanoparticles as Potential Tracers for SPECT Imaging.
International journal of nanomedicine.
2021; 16(?):5665-5673. doi:
10.2147/ijn.s325791. [PMID: 34447248] - Ying Li, Min Cai, Ruihuan Zhang, Jun Wang, Huijing Zhu, Chunhua Wang, Weiqi Min, Yiheng Chen, Li Yan. Investigating the Preventive Effects of 99Tc-Methylenediphosphonate on a Glucocorticoid-Induced Osteoporosis Rabbit Model.
Current topics in medicinal chemistry.
2021; 21(26):2425-2433. doi:
10.2174/1568026621666210804114744. [PMID: 34348621] - Kuldeep Rajpoot, Sunil K Jain. 99mTc-labelled and pH-awakened microbeads entrapping surface-modified lipid nanoparticles for the augmented effect of oxaliplatin in the therapy of colorectal cancer.
Journal of microencapsulation.
2020 Dec; 37(8):609-623. doi:
10.1080/02652048.2020.1829141. [PMID: 32985297] - Evren Atlihan Gundogdu, Emine Selin Demir, Meliha Ekinci, Emre Ozgenc, Derya Ilem Ozdemir, Zeynep Senyigit, Makbule Asikoglu. The effect of radiolabeled nanostructured lipid carrier systems containing imatinib mesylate on NIH-3T3 and CRL-1739 cells.
Drug delivery.
2020 Dec; 27(1):1695-1703. doi:
10.1080/10717544.2020.1841337. [PMID: 33263456] - Tomoya Uehara, Naoki Kanazawa, Chie Suzuki, Yuki Mizuno, Hiroyuki Suzuki, Hirofumi Hanaoka, Yasushi Arano. Renal Handling of 99mTc-Labeled Antibody Fab Fragments with a Linkage Cleavable by Enzymes on Brush Border Membrane.
Bioconjugate chemistry.
2020 11; 31(11):2618-2627. doi:
10.1021/acs.bioconjchem.0c00541. [PMID: 33085454] - Jiefu Zheng, Yiyan Liu. 99mTc-Leukocyte Scintigraphy Revealed Viral Pulmonary Infection in a COVID-19 Patient.
Clinical nuclear medicine.
2020 Oct; 45(10):821-823. doi:
10.1097/rlu.0000000000003219. [PMID: 32701817] - Zheng Qiao, Jingli Xu, Rene Gonzalez, Yubin Miao. Novel [99mTc]-Tricarbonyl-NOTA-Conjugated Lactam-Cyclized Alpha-MSH Peptide with Enhanced Melanoma Uptake and Reduced Renal Uptake.
Molecular pharmaceutics.
2020 09; 17(9):3581-3588. doi:
10.1021/acs.molpharmaceut.0c00606. [PMID: 32663011] - Saedeh Zamani, Mehdi Shafeie-Ardestani, Ahmad Bitarafan-Rajabi, Ali Khalaj, Omid Sabzevari. Synthesis, radiolabelling, and biological assessment of folic acid-conjugated G-3 99mTc-dendrimer as the breast cancer molecular imaging agent.
IET nanobiotechnology.
2020 Sep; 14(7):628-634. doi:
10.1049/iet-nbt.2020.0176. [PMID: 33010140] - Anfal M Alkandari, Medhat W Shafaa, Yasser M Alsayed. Preclinical Assessment of 99mTc-Labeled Liposome Agents as an Effective Tracer in Nuclear Medicine.
Journal of nuclear medicine technology.
2020 Sep; 48(3):269-273. doi:
10.2967/jnmt.119.239756. [PMID: 32518123] - Walaa I El-Ghareb, Mohamed M Swidan, Ismail T Ibrahim, Ahmed Abd El-Bary, Mina Ibrahim Tadros, Tamer M Sakr. 99mTc-doxorubicin-loaded gallic acid-gold nanoparticles (99mTc-DOX-loaded GA-Au NPs) as a multifunctional theranostic agent.
International journal of pharmaceutics.
2020 Aug; 586(?):119514. doi:
10.1016/j.ijpharm.2020.119514. [PMID: 32565281] - Julekha Kazi, Ramkrishna Sen, Soumya Ganguly, Tarun Jha, Shantanu Ganguly, Mita Chatterjee Debnath. Folate decorated epigallocatechin-3-gallate (EGCG) loaded PLGA nanoparticles; in-vitro and in-vivo targeting efficacy against MDA-MB-231 tumor xenograft.
International journal of pharmaceutics.
2020 Jul; 585(?):119449. doi:
10.1016/j.ijpharm.2020.119449. [PMID: 32464231] - Zhihui Hong, Shengming Deng, Yizhen Shi, Yichi Xie, Jiaxi You, Wei Wang, Hong Huang, Zengli Liu. Pretargeted radioimmunoimaging with a biotinylated D-D3 construct and 99mTc-DTPA-biotin: strategies for early diagnosis of small cell lung cancer.
The Journal of international medical research.
2020 Jul; 48(7):300060520937162. doi:
10.1177/0300060520937162. [PMID: 32692291] - Minh Phuong Nguyen, Ruud M Ramakers, Chris Kamphuis, Sofia Koustoulidou, Marlies C Goorden, Freek J Beekman. EXIRAD-3D: Fast automated three-dimensional autoradiography.
Nuclear medicine and biology.
2020 Jul; 86-87(?):59-65. doi:
10.1016/j.nucmedbio.2020.06.001. [PMID: 32534896] - M de Arcocha-Torres, G Quincoces, A L Martínez-López, A Erhard, M Collantes, I Martínez-Rodríguez, M Ecay, I Banzo, J M Irache, I Peñuelas. Preparation, radiolabeling with 99mTc and 67Ga and biodistribution studies of albumin nanoparticles covered with polymers.
Revista espanola de medicina nuclear e imagen molecular.
2020 Jul; 39(4):225-232. doi:
10.1016/j.remn.2020.02.002. [PMID: 32201272] - Hesham A Shamsel-Din, Mohamed A Gizawy, Elsayed G Zaki, Amr Elgendy. A novel 99m Tc-diester complex as tumor targeting agent: Synthesis, radiolabeling, and biological distribution study.
Journal of labelled compounds & radiopharmaceuticals.
2020 06; 63(8):376-385. doi:
10.1002/jlcr.3841. [PMID: 32335935] - Mazen Hanna, Frederick L Ruberg, Mathew S Maurer, Angela Dispenzieri, Sharmila Dorbala, Rodney H Falk, James Hoffman, Wael Jaber, Prem Soman, Ronald M Witteles, Martha Grogan. Cardiac Scintigraphy With Technetium-99m-Labeled Bone-Seeking Tracers for Suspected Amyloidosis: JACC Review Topic of the Week.
Journal of the American College of Cardiology.
2020 06; 75(22):2851-2862. doi:
10.1016/j.jacc.2020.04.022. [PMID: 32498813] - Mona Mosayebnia, Zahra Hajimahdi, Davood Beiki, Maliheh Rezaeianpour, Maliheh Hajiramezanali, Parham Geramifar, Omid Sabzevari, Mohsen Amini, Dara Hatamabadi, Soraya Shahhosseini. Design, synthesis, radiolabeling and biological evaluation of new urea-based peptides targeting prostate specific membrane antigen.
Bioorganic chemistry.
2020 06; 99(?):103743. doi:
10.1016/j.bioorg.2020.103743. [PMID: 32217372] - Jonathan Vigne, Thomas Cognet, Kevin Guedj, Marion Morvan, Olivier Merceron, Liliane Louedec, Christine Choqueux, Antonino Nicoletti, Brigitte Escoubet, Frederic Chaubet, Jean-Baptiste Michel, François Rouzet. Early Detection of Localized Immunity in Experimental Autoimmune Myocarditis Using [99mTc]Fucoidan SPECT.
Molecular imaging and biology.
2020 06; 22(3):643-652. doi:
10.1007/s11307-019-01420-8. [PMID: 31432389] - Naser Mohtavinejad, Massoud Amanlou, Ahmad Bitarafan-Rajabi, Ali Khalaj, Ali Pormohammad, Mehdi Shafiee Ardestani. Technetium-99 m-PEGylated dendrimer-G2-(Dabcyle-Lys6,Phe7)-pHBSP: A novel Nano-Radiotracer for molecular and early detecting of cardiac ischemic region.
Bioorganic chemistry.
2020 05; 98(?):103731. doi:
10.1016/j.bioorg.2020.103731. [PMID: 32171100] - Asghar Narmani, Monire Alsadat Afzali Arani, Javad Mohammadnejad, Ali Zaman Vaziri, Sedigheh Solymani, Kamal Yavari, Farideh Talebi, Simin Janitabar Darzi. Breast Tumor Targeting with PAMAM-PEG-5FU-99mTc As a New Therapeutic Nanocomplex: In In-vitro and In-vivo studies.
Biomedical microdevices.
2020 04; 22(2):31. doi:
10.1007/s10544-020-00485-5. [PMID: 32335724] - Ananda Kumar Kanduluru, Madduri Srinivasarao, Charity Wayua, Philip S Low. Evaluation of a Neurokinin-1 Receptor-Targeted Technetium-99m Conjugate for Neuroendocrine Cancer Imaging.
Molecular imaging and biology.
2020 04; 22(2):377-383. doi:
10.1007/s11307-019-01391-w. [PMID: 31292915] - Elahe Kamelnia, Adeleh Divsalar, Majid Darroudi, Parichehr Yaghmaei, Kayvan Sadri. Synthesis, 99mTc-radiolabeling, and biodistribution of new cellulose nanocrystals from Dorema kopetdaghens.
International journal of biological macromolecules.
2020 Mar; 146(?):299-310. doi:
10.1016/j.ijbiomac.2019.12.179. [PMID: 31881307] - J Wang, E H Bailey, H K Sanders, M Izquierdo, N M J Crout, G Shaw, L Yang, H Li, B Wei, S D Young. Using chemical fractionation and speciation to describe uptake of technetium, iodine and selenium by Agrostis capillaris and Lolium perenne.
Journal of environmental radioactivity.
2020 Feb; 212(?):106131. doi:
10.1016/j.jenvrad.2019.106131. [PMID: 31885365] - Saray Argibay-Otero, Lurdes Gano, Célia Fernandes, António Paulo, Rosa Carballo, Ezequiel M Vázquez-López. Chemical and biological studies of Re(I)/Tc(I) thiosemicarbazonate complexes relevant for the design of radiopharmaceuticals.
Journal of inorganic biochemistry.
2020 02; 203(?):110917. doi:
10.1016/j.jinorgbio.2019.110917. [PMID: 31766012] - Burcu Aydın, Eser Uçar, Volkan Tekin, Çiğdem İçhedef, Serap Teksöz. Biocompatible Delivery System for Metformin: Characterization, Radiolabeling and In Vitro Studies.
Anti-cancer agents in medicinal chemistry.
2020; 20(13):1626-1634. doi:
10.2174/1871520620666200423081235. [PMID: 32324524] - Paola Vallejo-Armenta, Clara Santos-Cuevas, Juan Soto-Andonaegui, Rosa M Villanueva-Pérez, Jorge I González-Díaz, Francisco O García-Pérez, Angélica Arrellano-Zarate, Myrna Luna-Gutiérrez, Erika Azorín-Vega, Blanca Ocampo-García, Guillermina Ferro-Flores. 99mTc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans.
Contrast media & molecular imaging.
2020; 2020(?):2525037. doi:
10.1155/2020/2525037. [PMID: 32410920] - Paria Mojarrad, Saeedeh Zamani, Mohammad Seyedhamzeh, Farnoor Davachi Omoomi, Naeim Karimpourfard, Shahin Hadadian, Seyed Esmadeil Sadat Ebrahimi, Morteza Pirali Hamedani, Jafar Farzaneh, Mehdi Shafiee Ardestani. Novel radiopharmaceutical (Technetium-99m)-(DOTA-NHS-ester)-Methionine as a SPECT-CT tumor imaging agent.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2020 Jan; 141(?):105112. doi:
10.1016/j.ejps.2019.105112. [PMID: 31629917] - Muhammad Isa Khan, Umme Farwa, Tahir Iqbal, Saadat Ali, Aalia Nazir, Mohsin Ijaz. Comparison of 99mTc Injected Activity with Prescribed Activity in Four Types of Nuclear Medicine Exams.
Current radiopharmaceuticals.
2020; 13(1):80-85. doi:
10.2174/1874471012666190620144803. [PMID: 31258094] - Chong Huang, Fen Chen, Ling Zhang, Yue Yang, Xinggang Yang, Weisan Pan. 99mTc Radiolabeled HA/TPGS-Based Curcumin-Loaded Nanoparticle for Breast Cancer Synergistic Theranostics: Design, in vitro and in vivo Evaluation.
International journal of nanomedicine.
2020; 15(?):2987-2998. doi:
10.2147/ijn.s242490. [PMID: 32431497] - Ayfer Y Kilcar, Onur Yildiz, Tansu Dogan, Ezgi Sulu, Gokhan Takan, Fazilet Z B Muftuler. The Effect of Bitter Melon (Momordica charantia) Extract on the Uptake of 99mTc Labeled Paclitaxel: In Vitro Monitoring in Breast Cancer Cells.
Anti-cancer agents in medicinal chemistry.
2020; 20(12):1497-1503. doi:
10.2174/1871520620666200424124746. [PMID: 32329694] - Hongwei Xu, Shengpan Jiang, Jimin Wang, Xuebing Li, Tingwei Wu, Pengfei Xu, Ralph Santos-Oliveira, Aohua Zhang. Radioactive Gold Nanoparticle in Two Forms (19879Au GNPs and 99mTc-GNPs) for Lung Cancer Antiproliferative Induction and Intralesional Imaging: A Proof of Concept.
Anti-cancer agents in medicinal chemistry.
2020; 20(14):1648-1653. doi:
10.2174/1871520620666200529113818. [PMID: 32469704] - Marco Giovanni Persico, Manuela Marenco, Gianluca De Matteis, Giulia Manfrinato, Giorgio Cavenaghi, Adele Sgarella, Carlo Aprile, Lorenzo Lodola. 99mTc-68Ga-ICG-Labelled Macroaggregates and Nanocolloids of Human Serum Albumin: Synthesis Procedures of a Trimodal Imaging Agent Using Commercial Kits.
Contrast media & molecular imaging.
2020; 2020(?):3629705. doi:
10.1155/2020/3629705. [PMID: 32410921] - Arezou Masteri Farahani, Fariba Maleki, Nourollah Sadeghzadeh, Saeid Abediankenari, Seyed Mohammad Abedi, Mostafa Erfani. Evaluation of a New 99mTc-labeled GnRH Analogue as a Possible Imaging Agent for Prostate Cancer Detection.
Anti-cancer agents in medicinal chemistry.
2020; 20(14):1695-1703. doi:
10.2174/1871520620666200619175352. [PMID: 32560611] - Yaqun Jiang, Yongkang Gai, Yu Long, Qingyao Liu, Chunbao Liu, Yongxue Zhang, Xiaoli Lan. Application and Evaluation of [99mTc]-Labeled Peptide Nucleic Acid Targeting MicroRNA-155 in Breast Cancer Imaging.
Molecular imaging.
2020 Jan; 19(?):1536012120916124. doi:
10.1177/1536012120916124. [PMID: 32559121] - C Vairo, M Collantes, G Quincoces, S Villullas, I Peñuelas, M Pastor, A G Gil, E Gainza, R M Hernandez, M Igartua, G Gainza. Preclinical safety of topically administered nanostructured lipid carriers (NLC) for wound healing application: biodistribution and toxicity studies.
International journal of pharmaceutics.
2019 Oct; 569(?):118484. doi:
10.1016/j.ijpharm.2019.118484. [PMID: 31260785] - Makoto Sakai, Yoshiki Kubota, Raj Kumar Parajuli, Mikiko Kikuchi, Kazuo Arakawa, Takashi Nakano. Compton imaging with 99mTc for human imaging.
Scientific reports.
2019 09; 9(1):12906. doi:
10.1038/s41598-019-49130-z. [PMID: 31501461] - Subhani M Okarvi, Ibrahim AlJammaz. Development of the Tumor-Specific Antigen-Derived Synthetic Peptides as Potential Candidates for Targeting Breast and Other Possible Human Carcinomas.
Molecules (Basel, Switzerland).
2019 Aug; 24(17):. doi:
10.3390/molecules24173142. [PMID: 31470531] - Jiajia Liang, Qi Luo, Dongjian Zhang, Qiaomei Jin, Lichao Liu, Wei Liu, Meng Gao, Jian Zhang, Zhiqi Yin. SPECT Imaging of Treatment-Related Tumor Necrosis Using Technetium-99m-Labeled Rhein.
Molecular imaging and biology.
2019 08; 21(4):660-668. doi:
10.1007/s11307-018-1285-9. [PMID: 30338432] - Nicola Tregay, Malcolm Begg, Anthony Cahn, Neda Farahi, Kathryn Povey, Sujith Madhavan, Rosalind Simmonds, Daniel Gillett, Chandra Solanki, Anna Wong, Joanna Maison, Mark Lennon, Glyn Bradley, Emily Jarvis, Marius de Groot, Fred Wilson, Judith Babar, A Michael Peters, Edith M Hessel, Edwin R Chilvers. Use of autologous 99mTechnetium-labelled neutrophils to quantify lung neutrophil clearance in COPD.
Thorax.
2019 07; 74(7):659-666. doi:
10.1136/thoraxjnl-2018-212509. [PMID: 30674586] - Richard O Francis, Sonia Mahajan, Francesca Rapido, Francesca La Carpia, Mark Soffing, Chaitanya Divgi, Randy Yeh, Akiva Mintz, Lenhurst Leslie, Irina Agrest, Matthew S Karafin, Yelena Ginzburg, Beth H Shaz, Steven L Spitalnik, Joseph Schwartz, Tiffany Thomas, Xiaoyun Fu, Pascal Amireault, Pierre Buffet, James C Zimring, Angelo D'Alessandro, Eldad A Hod. Reexamination of the chromium-51-labeled posttransfusion red blood cell recovery method.
Transfusion.
2019 07; 59(7):2264-2275. doi:
10.1111/trf.15310. [PMID: 31002399] - Syed Faheem Askari Rizvi, Saleha Tariq, Muhammad Mehdi, Ahmad Junaid Hassan. Synthesis of 99m Tc-roxithromycin: A novel diagnostic agent to discriminate between septic and aseptic inflammation.
Chemical biology & drug design.
2019 06; 93(6):1166-1174. doi:
10.1111/cbdd.13412. [PMID: 30370631] - Sook Sam Leong, Jeannie Hsiu Ding Wong, Mohammad Nazri Md Shah, Anushya Vijayananthan, Maisarah Jalalonmuhali, Kwan Hoong Ng. Comparison of Shear Wave Elastography and Conventional Ultrasound in Assessing Kidney Function as Measured Using 51Cr-ethylenediaminetetraacetic Acid and 99Tc-Dimercaptosuccinic Acid.
Ultrasound in medicine & biology.
2019 06; 45(6):1417-1426. doi:
10.1016/j.ultrasmedbio.2019.01.024. [PMID: 30962016] - Meysam Eyvazlou, Ali Dadashpour Ahangar, Azin Rahimi, Mohammad Reza Davarpanah, Seyed Soheil Sayyahi, Mehdi Mohebali. Human reliability assessment in a 99Mo/99mTc generator production facility using the standardized plant analysis risk-human (SPAR-H) technique.
International journal of occupational safety and ergonomics : JOSE.
2019 Jun; 25(2):321-330. doi:
10.1080/10803548.2017.1415832. [PMID: 29227214] - S E Miranda, J A Lemos, R S Fernandes, F M Ottoni, R J Alves, A Ferretti, D Rubello, V N Cardoso, A L Branco de Barros. Technetium-99m-labeled lapachol as an imaging probe for breast tumor identification.
Revista espanola de medicina nuclear e imagen molecular.
2019 May; 38(3):167-172. doi:
10.1016/j.remn.2018.10.006. [PMID: 30679039] - Bárbara Bruna Ribeiro de Oliveira-Mendes, Sued Eustáquio Mendes Miranda, Douglas Ferreira Sales-Medina, Bárbara de Freitas Magalhães, Yan Kalapothakis, Renan Pedra de Souza, Valbert Nascimento Cardoso, André Luís Branco de Barros, Clara Guerra-Duarte, Evanguedes Kalapothakis, Carolina Campolina Rebello Horta. Inhibition of Tityus serrulatus venom hyaluronidase affects venom biodistribution.
PLoS neglected tropical diseases.
2019 04; 13(4):e0007048. doi:
10.1371/journal.pntd.0007048. [PMID: 31002673] - Lauren L Radford, Dionysia Papagiannopoulou, Fabio Gallazzi, Ashley Berendzen, Lisa Watkinson, Terry Carmack, Michael R Lewis, Silvia S Jurisson, Heather M Hennkens. Synthesis and evaluation of Re/99mTc(I) complexes bearing a somatostatin receptor-targeting antagonist and labeled via a novel [N,S,O] clickable bifunctional chelating agent.
Bioorganic & medicinal chemistry.
2019 02; 27(3):492-501. doi:
10.1016/j.bmc.2018.12.028. [PMID: 30594453] - Shirleide Santos Nunes, Renata Salgado Fernandes, Carolina Henriques Cavalcante, Isabela da Costa César, Elaine Amaral Leite, Sávia Caldeira Araújo Lopes, Alice Ferretti, Domenico Rubello, Danyelle M Townsend, Mônica Cristina de Oliveira, Valbert Nascimento Cardoso, André Luís Branco de Barros. Influence of PEG coating on the biodistribution and tumor accumulation of pH-sensitive liposomes.
Drug delivery and translational research.
2019 02; 9(1):123-130. doi:
10.1007/s13346-018-0583-8. [PMID: 30187353] - Cinzia Valzania, Mauro Biffi, Rachele Bonfiglioli, Francesco Fallani, Cristian Martignani, Igor Diemberger, Matteo Ziacchi, Jessica Frisoni, Luciana Tomasi, Stefano Fanti, Claudio Rapezzi, Giuseppe Boriani. Effects of cardiac resynchronization therapy on right ventricular function during rest and exercise, as assessed by radionuclide angiography, and on NT-proBNP levels.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.
2019 Feb; 26(1):123-132. doi:
10.1007/s12350-017-0971-3. [PMID: 28667454] - Mick M Welling, Silvia J Spa, Danny M van Willigen, Daphne D D Rietbergen, Meta Roestenberg, Tessa Buckle, Fijs W B van Leeuwen. In vivo stability of supramolecular host-guest complexes monitored by dual-isotope multiplexing in a pre-targeting model of experimental liver radioembolization.
Journal of controlled release : official journal of the Controlled Release Society.
2019 01; 293(?):126-134. doi:
10.1016/j.jconrel.2018.11.020. [PMID: 30485797] - Ram Yadav, Samarth Agarwal, Satyanarayan Sankhwar, Apul Goel, Manoj Kumar, Manmeet Singh, Ruchir Aeron, Vikas Kumar. A prospective study evaluating impact on renal function following percutaneous nephrolithotomy using Tc99m ethylenedicysteine renal scan: Does multiplicity of access tracts play a role?.
Investigative and clinical urology.
2019 Jan; 60(1):21-28. doi:
10.4111/icu.2019.60.1.21. [PMID: 30637357] - Soumen Das, Navin Sakhare, Anupam Mathur, Madhava B Mallia, Shubhangi Mirapurkar, M Sheela, H D Sarma, S S Sachdev, Ashutosh Dash. Synthesis and evaluation of 99mTc-analogues of [123/131I]mIBG prepared via [99mTc][Tc(CO)3(H2O)3]+ synthon for targeting norepinephrine transporter.
Nuclear medicine and biology.
2019 Jan; 68-69(?):49-57. doi:
10.1016/j.nucmedbio.2019.01.001. [PMID: 30770228] - Nasrin Abbasi Gharibkandi, Sajjad Molavipordanjani, Jafar Akbari, Seyed Jalal Hosseinimehr. Pharmacokinetic Evaluation of 99mTc-radiolabeled Solid Lipid Nanoparticles and Chitosan Coated Solid Lipid Nanoparticles.
Current drug metabolism.
2019; 20(13):1044-1052. doi:
10.2174/1389200220666191112145808. [PMID: 31721707] - Muhammad Hammadah, Jeong Hwan Kim, Ayman Samman Tahhan, Bryan Kindya, Chang Liu, Yi-An Ko, Ibhar Al Mheid, Kobina Wilmot, Ronnie Ramadan, Ayman Alkhoder, Fahad Choudhary, Mohamad Mazen Gafeer, Naser Abdelhadi, Pratik Pimple, Pratik Sandesara, Bruno B Lima, Amit J Shah, Laura Ward, Michael Kutner, J Douglas Bremner, David S Sheps, Paolo Raggi, Laurence S Sperling, Viola Vaccarino, Arshed A Quyyumi. Use of High-Sensitivity Cardiac Troponin for the Exclusion of Inducible Myocardial Ischemia: A Cohort Study.
Annals of internal medicine.
2018 12; 169(11):751-760. doi:
10.7326/m18-0670. [PMID: 30398528] - A Ballini, S Cantore, C Altini, G Dipalma, C Ferrari, A Niccoli Asabella, G Rubini, F Inchingolo. 99mTc-diphosphonates bone scintigraphy for vitality evaluation in cleft palate.
European review for medical and pharmacological sciences.
2018 12; 22(23):8497-8501. doi:
10.26355/eurrev_201812_16550. [PMID: 30556892] - Muhammad Usman Akbar. Preparation, optimization and pharmacological evaluation of 99mTc- 4-hydroxy-3-(2-hydroxy-3-methoxybenzylideneamino) benzoic acid complex: as a novel potential radiopharmaceutical agent with hepatobiliary excretion.
Molecular biology reports.
2018 Dec; 45(6):2717-2723. doi:
10.1007/s11033-018-4402-6. [PMID: 30328001] - Syed F A Rizvi, Saleha Tariq, Muhammad Mehdi. Synthesis and preclinical evaluation of bactericidal agent isolated from soil bacterium (Streptomyces): a novel diagnostic technique to enhance anticancer efficacy through radiosynthesis.
Nuclear medicine communications.
2018 Dec; 39(12):1081-1090. doi:
10.1097/mnm.0000000000000916. [PMID: 30256273] - Dawn A Montgomery, Nimisha Edayilam, Nishanth Tharayil, Brian A Powell, Nicole E Martinez. The Uptake and Translocation of 99Tc, 133Cs, 237Np, and 238U Into Andropogon Virginicus With Consideration of Plant Life Stage.
Health physics.
2018 11; 115(5):550-560. doi:
10.1097/hp.0000000000000848. [PMID: 29878916] - Liyun Niu, Jian Li, Ruolan Gu, Zhuona Wu, Xiaoxia Zhu, Hui Gan, Baiping Ma, Bing Jia, Fan Wang, Zhiyun Meng, Xinyu Wang, Guifang Dou. An optimized LC-MS/MS method for determination of HYNIC-3PRGD2, a new promising imaging agent for tumor targeting, in rat plasma and its application.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 Sep; 1095(?):142-148. doi:
10.1016/j.jchromb.2018.07.026. [PMID: 30077094] - Xuran Zhang, Qing Ruan, Xiaojiang Duan, Qianqian Gan, Xiaoqing Song, Sian Fang, Xiao Lin, Jin Du, Junbo Zhang. Novel 99mTc-Labeled Glucose Derivative for Single Photon Emission Computed Tomography: A Promising Tumor Imaging Agent.
Molecular pharmaceutics.
2018 08; 15(8):3417-3424. doi:
10.1021/acs.molpharmaceut.8b00415. [PMID: 29985620] - Sarah Weinberger, Carola Klarholz-Pevere, Lutz Liefeldt, Michael Baeder, Nico Steckhan, Frank Friedersdorff. Influence of CT-based depth correction of renal scintigraphy in evaluation of living kidney donors on side selection and postoperative renal function: is it necessary to know the relative renal function?.
World journal of urology.
2018 Aug; 36(8):1327-1332. doi:
10.1007/s00345-018-2272-0. [PMID: 29569036] - Zahra Shaghaghi, Seyed Mohammad Abedi, Seyed Jalal Hosseinimehr. Tricine co-ligand improved the efficacy of 99mTc-HYNIC-(Ser)3-J18 peptide for targeting and imaging of non-small-cell lung cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Aug; 104(?):325-331. doi:
10.1016/j.biopha.2018.05.037. [PMID: 29775901] - Vera F C Ferreira, Bruno L Oliveira, João D Santos, João D G Correia, Carlos M Farinha, Filipa Mendes. Targeting of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein with a Technetium-99m Imaging Probe.
ChemMedChem.
2018 07; 13(14):1469-1478. doi:
10.1002/cmdc.201800187. [PMID: 29864241] - James H Yiin, Jeri L Anderson, Stephen J Bertke, David J Tollerud. Dose-response relationships between internally-deposited uranium and select health outcomes in gaseous diffusion plant workers, 1948-2011.
American journal of industrial medicine.
2018 07; 61(7):605-614. doi:
10.1002/ajim.22858. [PMID: 29744908] - Farzaneh Rezazadeh, Nourollah Sadeghzadeh, Seyed Mohammad Abedi, Saeid Abediankenari. 99mTc labeled D(LPR): A novel retro-inverso peptide for VEGF receptor-1 targeted tumor imaging.
Nuclear medicine and biology.
2018 Jul; 62-63(?):54-62. doi:
10.1016/j.nucmedbio.2018.05.005. [PMID: 29885559] - Chie Suzuki, Tomoya Uehara, Naoki Kanazawa, Shota Wada, Hiroyuki Suzuki, Yasushi Arano. Preferential Cleavage of a Tripeptide Linkage by Enzymes on Renal Brush Border Membrane To Reduce Renal Radioactivity Levels of Radiolabeled Antibody Fragments.
Journal of medicinal chemistry.
2018 06; 61(12):5257-5268. doi:
10.1021/acs.jmedchem.8b00198. [PMID: 29869881] - Yu Zhang, Ziming Zheng, Xiawen Yang, Xianglin Pan, Lianglan Yin, Xiao Huang, Qiang Li, Yamin Shu, Qilin Zhang, Kaiping Wang. A sensitive and rapid radiolabelling method for the in vivo pharmacokinetic study of lentinan.
Food & function.
2018 Jun; 9(6):3114-3125. doi:
10.1039/c8fo00272j. [PMID: 29876541] - Teele Kuusk, Roderick De Bruijn, Oscar R Brouwer, Jeroen De Jong, Maarten Donswijk, Nikolaos Grivas, Kees Hendricksen, Simon Horenblas, Warner Prevoo, Renato A Valdés Olmos, Henk G Van Der Poel, Bas W G Van Rhijn, Esther M Wit, Axel Bex. Lymphatic Drainage from Renal Tumors In Vivo: A Prospective Sentinel Node Study Using SPECT/CT Imaging.
The Journal of urology.
2018 06; 199(6):1426-1432. doi:
10.1016/j.juro.2017.11.112. [PMID: 29223390] - Yunier Rodríguez-Álvarez, Ania Cabrales-Rico, Alejandro Perera-Pintado, Anais Prats-Capote, Hilda E Garay-Pérez, Osvaldo Reyes-Acosta, Erik Pérez-García, Araceli Chico-Capote, Alicia Santos-Savio. In vitro and in vivo characterization of an interleukin-15 antagonist peptide by metabolic stability, 99m Tc-labeling, and biological activity assays.
Journal of peptide science : an official publication of the European Peptide Society.
2018 Jun; 24(4-5):e3078. doi:
10.1002/psc.3078. [PMID: 29656472]
