TSQ (BioDeep_00000707677)

   


代谢物信息卡片


N-(6-Methoxy-8-quinolyl)-4-toluenesulfonamide

化学式: C17H16N2O3S (328.08815860000004)
中文名称: N-(6-甲氧基-8-喹啉基)对甲苯磺酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC2=C3C(=CC(=C2)OC)C=CC=N3
InChI: InChI=1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

2 个代谢物同义名

N-(6-Methoxy-8-quinolyl)-4-toluenesulfonamide; TSQ



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yi Hu, Emme C K Lin, Lan M Pham, Julia Cajica, Christopher M Amantea, Eric Okerberg, Heidi E Brown, Allister Fraser, Lingling Du, Yasushi Kohno, Junichi Ishiyama, John W Kozarich, Kevin R Shreder. Amides of 4-hydroxy-8-methanesulfonylamino-quinoline-2-carboxylic acid as zinc-dependent inhibitors of Lp-PLA₂. Bioorganic & medicinal chemistry letters. 2013 Mar; 23(5):1553-6. doi: 10.1016/j.bmcl.2012.11.048. [PMID: 23333209]
  • Jan Hošek, Radka Novotná, Petr Babula, Ján Vančo, Zdeněk Trávníček. Zn(II)-Chlorido complexes of phytohormone kinetin and its derivatives modulate expression of inflammatory mediators in THP-1 cells. PloS one. 2013; 8(6):e65214. doi: 10.1371/journal.pone.0065214. [PMID: 23755195]
  • Andrew B Nowakowski, David H Petering. Reactions of the fluorescent sensor, Zinquin, with the zinc-proteome: adduct formation and ligand substitution. Inorganic chemistry. 2011 Oct; 50(20):10124-33. doi: 10.1021/ic201076w. [PMID: 21905645]
  • Jonathan L Eichelsdoerfer, Jeffrey A Evans, Susan A Slaugenhaupt, Math P Cuajungco. Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel. The Journal of biological chemistry. 2010 Nov; 285(45):34304-8. doi: 10.1074/jbc.c110.165480. [PMID: 20864526]
  • Sandra V Verstraeten, M Paola Zago, Gerardo G MacKenzie, Carl L Keen, Patricia I Oteiza. Influence of zinc deficiency on cell-membrane fluidity in Jurkat, 3T3 and IMR-32 cells. The Biochemical journal. 2004 Mar; 378(Pt 2):579-87. doi: 10.1042/bj20031054. [PMID: 14629198]
  • Shirley C Paski, Lore Covery, Angela Kummer, Zhaoming Xu. Role of metallothionein in regulating the abundance of histochemically reactive zinc in rat tissues. Canadian journal of physiology and pharmacology. 2003 Aug; 81(8):815-24. doi: 10.1139/y03-076. [PMID: 12897811]
  • P Marin, M Israël, J Glowinski, J Prémont. Routes of zinc entry in mouse cortical neurons: role in zinc-induced neurotoxicity. The European journal of neuroscience. 2000 Jan; 12(1):8-18. doi: 10.1046/j.1460-9568.2000.00875.x. [PMID: 10651855]
  • J C Andrews, J P Nolan, R H Hammerstedt, B D Bavister. Characterization of N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide for the detection of zinc in living sperm cells. Cytometry. 1995 Oct; 21(2):153-9. doi: 10.1002/cyto.990210207. [PMID: 8582235]
  • J G Reyes, M Santander, P L Martinez, R Arce, D J Benos. A fluorescence method to determine picomole amounts of Zn(II) in biological systems. Biological research. 1994; 27(1):49-56. doi: NULL. [PMID: 7647815]
  • R M Jindal, D W Gray, P McShane, P J Morris. Zinc-specific N-(6-methoxy-8-quinolyl)-para-toluenesulfonamide as a selective nontoxic fluorescence stain for pancreatic islets. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 1993 Jul; 68(4):196-205. doi: 10.3109/10520299309104698. [PMID: 8218572]