Edtmp (BioDeep_00000705276)
代谢物信息卡片
Ethylenebis(nitrilodimethylene)tetraphosphonic acid
化学式: C6H20N2O12P4 (435.99667200000005)
中文名称: 乙二胺四亚甲基膦酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CN(CP(=O)(O)O)CP(=O)(O)O)N(CP(=O)(O)O)CP(=O)(O)O
InChI: InChI=1S/C6H20N2O12P4/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)
描述信息
D064449 - Sequestering Agents > D002614 - Chelating Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lili Hao, Peng Wang, Zhenxu Wu, Zongliang Wang, Yu Wang, Yongzhan Zhu, Zhiqiang Xu, Min Guo, Jiansong Ji, Peibiao Zhang. EDTMP ligand-enhanced water interactions endowing iron oxide nanoparticles with dual-modal MRI contrast ability.
Journal of materials chemistry. B.
2021 11; 9(43):9055-9066. doi:
10.1039/d1tb01677f. [PMID: 34673872] - Domokos Máthé, Lajos Balogh, András Polyák, Réka Király, Teréz Márián, Dariusz Pawlak, John J Zaknun, Maroor R A Pillai, Gyozo A Jánoki. Multispecies animal investigation on biodistribution, pharmacokinetics and toxicity of 177Lu-EDTMP, a potential bone pain palliation agent.
Nuclear medicine and biology.
2010 Feb; 37(2):215-26. doi:
10.1016/j.nucmedbio.2009.09.004. [PMID: 20152721] - Mingming Su, Yunping Qiu, Wei Jia. A pilot study of antitumor effect of gallium ethylenediaminetetramethylene phosphonate [Ga(III)-EDTMP] in tumor-bearing rats.
Advances in therapy.
2005 Jul; 22(4):297-306. doi:
10.1007/bf02850079. [PMID: 16418139] - Martha Pedraza-López, Guillermina Ferro-Flores, Consuelo Arteaga de Murphy, Jose I Tendilla, Octavio Villanueva-Sánchez. Preparation of (166)Dy/(166)Ho-EDTMP: a potential in vivo generator system for bone marrow ablation.
Nuclear medicine communications.
2004 Jun; 25(6):615-21. doi:
10.1097/01.mnm.0000126516.57329.07. [PMID: 15167523] - Piotr Garnuszek, Dariusz Pawlak, Iwona Licińska, Anna Kamińska. Evaluation of a freeze-dried kit for EDTMP-based bone-seeking radiopharmaceuticals.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.
2003 Apr; 58(4):481-8. doi:
10.1016/s0969-8043(03)00057-5. [PMID: 12672628] - Adrian A Ammann. Determination of strong binding chelators and their metal complexes by anion-exchange chromatography and inductively coupled plasma mass spectrometry.
Journal of chromatography. A.
2002 Feb; 947(2):205-16. doi:
10.1016/s0021-9673(01)01607-7. [PMID: 11883654] - A M Clausen, A Subramanian, P W Carr. Purification of monoclonal antibodies from cell culture supernatants using a modified zirconia based cation-exchange support.
Journal of chromatography. A.
1999 Jan; 831(1):63-72. doi:
10.1016/s0021-9673(98)00999-6. [PMID: 10028281] - W F Goeckeler, L K Stoneburner, L P Kasi, F V Fossella, D R Price, W A Fordyce. Analysis of urine samples from metastatic bone cancer patients administered 153Sm-EDTMP.
Nuclear medicine and biology.
1993 Jul; 20(5):657-61. doi:
10.1016/0969-8051(93)90036-t. [PMID: 8358352] - Y Tanaka, A Saitou, O Saitou, T Masuhara. [Effects of EDTPO on hard tissues in rats. 2. Changes of serum components and morphology of hard tissues due to various doses of EDTPO].
Shigaku = Odontology; journal of Nihon Dental College.
1990 Oct; 78(3):575-91. doi:
NULL. [PMID: 2134805] - J C Lattimer, L A Corwin, J Stapleton, W A Volkert, G J Ehrhardt, A R Ketring, S K Anderson, J Simon, W F Goeckeler. Clinical and clinicopathologic response of canine bone tumor patients to treatment with samarium-153-EDTMP.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1990 Aug; 31(8):1316-25. doi:
NULL. [PMID: 2384798] - J C Lattimer, L A Corwin, J Stapleton, W A Volkert, G J Ehrhardt, A R Ketring, J E Hewett, J Simon, W F Goeckeler. Clinical and clinicopathologic effects of samarium-153-EDTMP administered intravenously to normal beagle dogs.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1990 May; 31(5):586-93. doi:
NULL. [PMID: 2341893] - N C Moore, J K Chipman. Effects of intraperitoneal administration of hexasodium N,N,N',N'-ethylenediaminetetramethylenephosphonate on rat bone metabolism.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1990 Apr; 14(3):491-501. doi:
10.1016/0272-0590(90)90253-g. [PMID: 2340979] - Y Tanaka, M Aizawa, T Masuhara. [Effects of EDTPO on hard tissues in rats. 1. Comparison of histological changes produced by same molar of EDTPO, HEBP and EDTA].
Shigaku = Odontology; journal of Nihon Dental College.
1989 Aug; 77(2):417-29. doi:
. [PMID: 2518739] - G Calvin, P H Long, K A Stitzel, R L Anderson, R R Balmbra, R D Bruce, A Bhatt, P M Miller, A Broadmeadow. Ethylenediaminetetra(methylenephosphonic acid): genotoxicity, biodistribution, and subchronic and chronic toxicity in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1988 Jul; 26(7):601-10. doi:
10.1016/0278-6915(88)90231-1. [PMID: 3181836] - S C Miller, W S Jee, D M Woodbury, J W Kemp. Effects of N,N,N',N'-ethylenediaminetetramethylene phosphonic acid and 1-hydroxyethylidene-1,1-bisphosphonic acid on calcium absorption, plasma calcium, longitudinal bone growth, and bone histology in the growing rat.
Toxicology and applied pharmacology.
1985 Feb; 77(2):230-9. doi:
10.1016/0041-008x(85)90322-9. [PMID: 3919462]