Vitamin E nicotinate (BioDeep_00000702495)
Secondary id: BioDeep_00000009411
Volatile Flavor Compounds
代谢物信息卡片
化学式: C35H53NO3 (535.4025228)
中文名称: (±)-α-烟酸生育酚, 维生素E烟酸酯, 烟酸维生素E
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(c(C)c(C)c2O1)OC(=O)c1cccnc1
InChI: InChI=1S/C35H53NO3/c1-24(2)13-9-14-25(3)15-10-16-26(4)17-11-20-35(8)21-19-31-29(7)32(27(5)28(6)33(31)39-35)38-34(37)30-18-12-22-36-23-30/h12,18,22-26H,9-11,13-17,19-21H2,1-8H3
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:32239
- KEGG: C12981
- KEGGdrug: D01530
- PubChem: 27990
- PubChem: 5500
- ChEMBL: CHEMBL1084541
- CAS: 43119-47-7
- CAS: 16676-75-8
- CAS: 51898-34-1
- CAS: 86362-36-9
- PubChem: 583370
- NIKKAJI: J299.341D
- RefMet: Vitamin E Nicotinate
- KNApSAcK: 32239
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - N Hidiroglou, M S Wolynetz, L R McDowell, A M Papas, M Antapli, N S Wilkinson. Serum total cholesterol, high-density lipoprotein-cholesterol and triglyceride concentrations in lambs following supplementation with various forms of tocopherol.
Reproduction, nutrition, development.
1993; 33(3):263-8. doi:
10.1051/rnd:19930308. [PMID: 8216754] - N Hidiroglou, L R McDowell, A M Papas, M Antapli, N S Wilkinson. Bioavailability of vitamin E compounds in lambs.
Journal of animal science.
1992 Aug; 70(8):2556-61. doi:
10.2527/1992.7082556x. [PMID: 1506317] - Y Ihara, K Nobukuni, R Namba, K Kamisaka, M Kibata, K Kajinami, H Fujita, H Mabuchi, T Shirabe, K Ohshima. A family of familial hypercholesterolemia with cerebral infarction and without coronary heart disease. An unusual case with corneal opacity, polyneuropathy and carpal tunnel syndrome in the family: therapy with probucol and tocopherol nicotinate.
Journal of the neurological sciences.
1991 Nov; 106(1):10-8. doi:
10.1016/0022-510x(91)90187-c. [PMID: 1779233] - M Hidiroglou, E Charmley. Comparative studies on bioavailability and tissue uptake of two intraruminally or intraperitoneally administered esters of alpha-tocopherol in sheep.
American journal of veterinary research.
1991 Apr; 52(4):640-2. doi:
NULL. [PMID: 2053738] - A Noma, S Maeda, M Okuno, A Abe, Y Muto. Reduction of serum lipoprotein(a) levels in hyperlipidaemic patients with alpha-tocopheryl nicotinate.
Atherosclerosis.
1990 Oct; 84(2-3):213-7. doi:
10.1016/0021-9150(90)90093-x. [PMID: 2149270] - H Tanaka, M Mino, T Takeuchi. A nutritional evaluation of vitamin E status in very low birth weight infants with respect to changes in plasma and red blood cell tocopherol levels.
Journal of nutritional science and vitaminology.
1988 Jun; 34(3):293-307. doi:
10.3177/jnsv.34.293. [PMID: 3183778] - A Funakoshi, T Kimura, H Shinozaki, H Ibayashi. Comparisons between absorption of vitamin E in patients with chronic pancreatitis and healthy controls: the bioavailability of vitamin E.
The Tohoku journal of experimental medicine.
1986 Apr; 148(4):393-401. doi:
10.1620/tjem.148.393. [PMID: 3738905] - N Suzuki, T Nakamura. Metabolism of the nicotinic acid moiety of d,l-alpha-tocopheryl nicotinate.
Journal of nutritional science and vitaminology.
1983 Apr; 29(2):93-103. doi:
10.3177/jnsv.29.93. [PMID: 6886843] - S Nakayama, K Negishi, K Sakamoto. [Effects of soysterol, pantethine and dl-alpha-tocopheryl nicotinate on hyperlipemia in rats (author's transl)].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1981 Sep; 78(3):191-202. doi:
10.1254/fpj.78.191. [PMID: 7327448] - J Hasegawa, Y Tomono, T Fujita, K Sugiyama, K Hamamura. The effect of food on the absorption of alpha-tocopheryl nicotinate in beagle dogs and human volunteers.
International journal of clinical pharmacology, therapy, and toxicology.
1981 May; 19(5):216-9. doi:
NULL. [PMID: 7251237] - T Matoba, H Kusumoto, Y Mizuki, K Yamada. Comparative double-blind trial of dl-alpha-tocopheryl nicotinate on vibration disease.
The Tohoku journal of experimental medicine.
1977 Sep; 123(1):67-75. doi:
10.1620/tjem.123.67. [PMID: 335571]