N-MeLys (BioDeep_00000702045)
代谢物信息卡片
化学式: C7H16N2O2 (160.12117160000003)
中文名称: Nα-甲基-L-赖氨酸盐酸盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNC(CCCCN)C(=O)O
InChI: InChI=1S/C7H16N2O2/c1-9-6(7(10)11)4-2-3-5-8/h6,9H,2-5,8H2,1H3,(H,10,11)/t6-/m0/s1
描述信息
A N-methyl-L-amino acid that is the N(alpha)-methyl derivative of L-lysine.
同义名列表
2 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:21756
- PubChem: 7010497
- ChEMBL: CHEMBL1240564
- CAS: 7431-89-2
- MetaboLights: MTBLC21756
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kylie M Wagstaff, Haran Sivakumaran, Steven M Heaton, David Harrich, David A Jans. Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus.
The Biochemical journal.
2012 May; 443(3):851-6. doi:
10.1042/bj20120150. [PMID: 22417684] - Klaus Fortschegger, Ramin Shiekhattar. Plant homeodomain fingers form a helping hand for transcription.
Epigenetics.
2011 Jan; 6(1):4-8. doi:
10.4161/epi.6.1.13297. [PMID: 20818169] - Wei Li, Zheng Wang, Jian Li, Hongchun Yang, Sujuan Cui, Xiaoxue Wang, Ligeng Ma. Overexpression of AtBMI1C, a polycomb group protein gene, accelerates flowering in Arabidopsis.
PloS one.
2011; 6(6):e21364. doi:
10.1371/journal.pone.0021364. [PMID: 21701597] - Zeneng Wang, W H Wilson Tang, Leslie Cho, Danielle M Brennan, Stanley L Hazen. Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
Arteriosclerosis, thrombosis, and vascular biology.
2009 Sep; 29(9):1383-91. doi:
10.1161/atvbaha.109.185645. [PMID: 19542023] - Tao Wu, Tiezheng Yuan, Sau-Na Tsai, Chunmei Wang, Sai-Ming Sun, Hon-Ming Lam, Sai-Ming Ngai. Mass spectrometry analysis of the variants of histone H3 and H4 of soybean and their post-translational modifications.
BMC plant biology.
2009 Jul; 9(?):98. doi:
10.1186/1471-2229-9-98. [PMID: 19643030] - Vivien Exner, Ernst Aichinger, Huan Shu, Thomas Wildhaber, Pietro Alfarano, Amedeo Caflisch, Wilhelm Gruissem, Claudia Köhler, Lars Hennig. The chromodomain of LIKE HETEROCHROMATIN PROTEIN 1 is essential for H3K27me3 binding and function during Arabidopsis development.
PloS one.
2009; 4(4):e5335. doi:
10.1371/journal.pone.0005335. [PMID: 19399177] - Wai Hong Wilson Tang, Wilson Tong, Kevin Shrestha, Zeneng Wang, Bruce S Levison, Brian Delfraino, Bo Hu, Richard W Troughton, Allan L Klein, Stanley L Hazen. Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure.
European heart journal.
2008 Oct; 29(20):2506-13. doi:
10.1093/eurheartj/ehn360. [PMID: 18687662] - Ernest Adeghate, Péter Sótonyi, Huba Kalász. Chronic experimental diabetes accelerates urinary elimination of deprenyl and its metabolites.
The open medicinal chemistry journal.
2008 Jan; 2(?):1-5. doi:
10.2174/1874104500802010001. [PMID: 19662137] - Max Haring, Sascha Offermann, Tanja Danker, Ina Horst, Christoph Peterhansel, Maike Stam. Chromatin immunoprecipitation: optimization, quantitative analysis and data normalization.
Plant methods.
2007 Sep; 3(?):11. doi:
10.1186/1746-4811-3-11. [PMID: 17892552] - Franziska Turck, François Roudier, Sara Farrona, Marie-Laure Martin-Magniette, Elodie Guillaume, Nicolas Buisine, Séverine Gagnot, Robert A Martienssen, George Coupland, Vincent Colot. Arabidopsis TFL2/LHP1 specifically associates with genes marked by trimethylation of histone H3 lysine 27.
PLoS genetics.
2007 Jun; 3(6):e86. doi:
10.1371/journal.pgen.0030086. [PMID: 17542647] - Lynnette M A Dirk, E Megan Flynn, Kevin Dietzel, Jean-François Couture, Raymond C Trievel, Robert L Houtz. Kinetic manifestation of processivity during multiple methylations catalyzed by SET domain protein methyltransferases.
Biochemistry.
2007 Mar; 46(12):3905-15. doi:
10.1021/bi6023644. [PMID: 17338551] - Huba Kalász, Imre Klebovich, Katalin Balogh-Nemes, Agnes Szilágyi, Mária Tihanyi, Tibor Szarvas, József Lengyel. Detection of N-monomethyl-lysine generated by metabolic transmethylation.
Analytical and bioanalytical chemistry.
2005 Jun; 382(3):760-4. doi:
10.1007/s00216-005-3089-4. [PMID: 15756599]