Hyaluronate Tetrasaccharide (BioDeep_00000701973)
代谢物信息卡片
(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
化学式: C28H44N2O23 (776.2334754000001)
中文名称: 透明质酸四糖
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)NC1C(C(C(OC1O)CO)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)NC(=O)C)O)O
InChI: InChI=1S/C28H44N2O23/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45)/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-/m1/s1
描述信息
同义名列表
2 个代谢物同义名
(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; Hyaluronate Tetrasaccharide
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:151449
- PubChem: 3084050
- ChEMBL: CHEMBL1697748
- CAS: 67007-54-9
- CAS: 57282-61-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- William S Turner, Xiaoling Wang, Scott Johnson, Christopher Medberry, Jose Mendez, Stephen F Badylak, Marian G McCord, Kara E McCloskey. Cardiac tissue development for delivery of embryonic stem cell-derived endothelial and cardiac cells in natural matrices.
Journal of biomedical materials research. Part B, Applied biomaterials.
2012 Nov; 100(8):2060-72. doi:
10.1002/jbm.b.32770. [PMID: 22888031] - Seiko Ohba, Wei Wang, Soichiro Itoh, Yuzo Takagi, Akiko Nagai, Kimihiro Yamashita. Efficacy of platelet-rich plasma gel and hyaluronan hydrogel as carriers of electrically polarized hydroxyapatite microgranules for accelerating bone formation.
Journal of biomedical materials research. Part A.
2012 Nov; 100(11):3167-76. doi:
10.1002/jbm.a.34250. [PMID: 22847859] - Carmen A Vlahu, Bregtje A Lemkes, Dirk G Struijk, Marion G Koopman, Raymond T Krediet, Hans Vink. Damage of the endothelial glycocalyx in dialysis patients.
Journal of the American Society of Nephrology : JASN.
2012 Nov; 23(11):1900-8. doi:
10.1681/asn.2011121181. [PMID: 23085635] - Davide Vigetti, Sara Deleonibus, Paola Moretto, Eugenia Karousou, Manuela Viola, Barbara Bartolini, Vincent C Hascall, Markku Tammi, Giancarlo De Luca, Alberto Passi. Role of UDP-N-acetylglucosamine (GlcNAc) and O-GlcNAcylation of hyaluronan synthase 2 in the control of chondroitin sulfate and hyaluronan synthesis.
The Journal of biological chemistry.
2012 Oct; 287(42):35544-35555. doi:
10.1074/jbc.m112.402347. [PMID: 22887999] - Katsuhito Miyazawa, Yoshitaka Takahashi, Nobuyo Morita, Manabu T Moriyama, Takeo Kosaka, Matomo Nishio, Tanihiro Yoshimoto, Koji Suzuki. Cyclooxygenase 2 and prostaglandin E2 regulate the attachment of calcium oxalate crystals to renal epithelial cells.
International journal of urology : official journal of the Japanese Urological Association.
2012 Oct; 19(10):936-43. doi:
10.1111/j.1442-2042.2012.03060.x. [PMID: 22640700] - Anne-Emilie Declèves, Nathalie Caron, Virginie Voisin, Alexandre Legrand, Nadine Bouby, Anne Kultti, Markku I Tammi, Bruno Flamion. Synthesis and fragmentation of hyaluronan in renal ischaemia.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2012 Oct; 27(10):3771-81. doi:
10.1093/ndt/gfs098. [PMID: 22529164] - Rosalia I Cordo Russo, Glenda Ernst, Silvina Lompardía, Guillermo Blanco, Élida Álvarez, Mariana G Garcia, Silvia Hajos. Increased hyaluronan levels and decreased dendritic cell activation are associated with tumor invasion in murine lymphoma cell lines.
Immunobiology.
2012 Sep; 217(9):842-50. doi:
10.1016/j.imbio.2011.12.006. [PMID: 22304941] - Paola Neri, Nizar J Bahlis. Targeting of adhesion molecules as a therapeutic strategy in multiple myeloma.
Current cancer drug targets.
2012 Sep; 12(7):776-96. doi:
10.2174/156800912802429337. [PMID: 22671924] - Padmini Sarathchandra, Ryszard T Smolenski, Ada H Y Yuen, Adrian H Chester, Steven Goldstein, Albert E Heacox, Magdi H Yacoub, Patricia M Taylor. Impact of γ-irradiation on extracellular matrix of porcine pulmonary valves.
The Journal of surgical research.
2012 Aug; 176(2):376-85. doi:
10.1016/j.jss.2011.10.011. [PMID: 22172131] - Mario Cabraja, Michaela Endres, Aldemar A Hegewald, Samuel Vetterlein, Claudius Thomé, Christian Woiciechowsky, Christian Kaps. A 3D environment for anulus fibrosus regeneration.
Journal of neurosurgery. Spine.
2012 Aug; 17(2):177-83. doi:
10.3171/2012.4.spine111095. [PMID: 22632174] - Ulla Lindqvist, Inger Phil-Lundin, Anna Engström-Laurent. Dermal distribution of hyaluronan in psoriatic arthritis; coexistence of CD44, MMP3 and MMP9.
Acta dermato-venereologica.
2012 Jul; 92(4):372-7. doi:
10.2340/00015555-1286. [PMID: 22278305] - Helene C D Osterholt, Bård Lundeland, Tonje Sonerud, Ola D Saugstad, Britt Nakstad. The impact of hyaluronan on monocyte Toll-like receptor expression in term infant cord blood.
Acta paediatrica (Oslo, Norway : 1992).
2012 Jul; 101(7):706-13. doi:
10.1111/j.1651-2227.2012.02650.x. [PMID: 22372604] - Kathleen M Job, Randal O Dull, Vladimir Hlady. Use of reflectance interference contrast microscopy to characterize the endothelial glycocalyx stiffness.
American journal of physiology. Lung cellular and molecular physiology.
2012 Jun; 302(12):L1242-9. doi:
10.1152/ajplung.00341.2011. [PMID: 22505668] - Marcin Okroj, Emelie Holmquist, Jonatan Sjölander, Leticia Corrales, Tore Saxne, Hans-Georg Wisniewski, Anna M Blom. Heavy chains of inter alpha inhibitor (IαI) inhibit the human complement system at early stages of the cascade.
The Journal of biological chemistry.
2012 Jun; 287(24):20100-10. doi:
10.1074/jbc.m111.324913. [PMID: 22528482] - Sara Stridh, Fredrik Palm, Peter Hansell. Renal interstitial hyaluronan: functional aspects during normal and pathological conditions.
American journal of physiology. Regulatory, integrative and comparative physiology.
2012 Jun; 302(11):R1235-49. doi:
10.1152/ajpregu.00332.2011. [PMID: 22513743] - Kiyohito Naito, Taiji Watari, Osamu Obayashi, Sadanobu Katsube, Isao Nagaoka, Kazuo Kaneko. Relationship between serum undercarboxylated osteocalcin and hyaluronan levels in patients with bilateral knee osteoarthritis.
International journal of molecular medicine.
2012 May; 29(5):756-60. doi:
10.3892/ijmm.2012.897. [PMID: 22294259] - Jingdong Qin, Evgeny Berdyshev, Christophe Poirer, Nancy B Schwartz, Glyn Dawson. Neutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of Akt.
The Journal of biological chemistry.
2012 Apr; 287(17):13620-32. doi:
10.1074/jbc.m111.304857. [PMID: 22383528] - Karin Benz, Claudia Stippich, Claudia Osswald, Christoph Gaissmaier, Nicolas Lembert, Andreas Badke, Eric Steck, Wilhelm K Aicher, Juergen A Mollenhauer. Rheological and biological properties of a hydrogel support for cells intended for intervertebral disc repair.
BMC musculoskeletal disorders.
2012 Apr; 13(?):54. doi:
10.1186/1471-2474-13-54. [PMID: 22490206] - Suzhen Zhang, Hua He, Anthony J Day, Scheffer C G Tseng. Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.
The Journal of biological chemistry.
2012 Apr; 287(15):12433-44. doi:
10.1074/jbc.m112.342873. [PMID: 22351758] - Anita T Layton, Rebecca L Gilbert, Thomas L Pannabecker. Isolated interstitial nodal spaces may facilitate preferential solute and fluid mixing in the rat renal inner medulla.
American journal of physiology. Renal physiology.
2012 Apr; 302(7):F830-9. doi:
10.1152/ajprenal.00539.2011. [PMID: 22160770] - V B Kraus, J Birmingham, T V Stabler, S Feng, D C Taylor, C T Moorman, W E Garrett, A P Toth. Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254).
Osteoarthritis and cartilage.
2012 Apr; 20(4):271-8. doi:
10.1016/j.joca.2011.12.009. [PMID: 22273632] - Tomoko Ito, Yoshiyuki Koyama, Makoto Otsuka. DNA complex-releasing system by injectable self-setting apatite cement.
The journal of gene medicine.
2012 Apr; 14(4):251-61. doi:
10.1002/jgm.2613. [PMID: 22367981] - Ádám Deák, Tímea Bácskai, Botond Gaál, Éva Rácz, Klara Matesz. Effect of unilateral labyrinthectomy on the molecular composition of perineuronal nets in the lateral vestibular nucleus of the rat.
Neuroscience letters.
2012 Mar; 513(1):1-5. doi:
10.1016/j.neulet.2012.01.076. [PMID: 22342907] - Florent Carn, Sylvain Guyot, Alain Baron, Javier Pérez, Eric Buhler, Dražen Zanchi. Structural properties of colloidal complexes between condensed tannins and polysaccharide hyaluronan.
Biomacromolecules.
2012 Mar; 13(3):751-9. doi:
10.1021/bm201674n. [PMID: 22304685] - Chul Min Ahn, Håkan Sandler, Tom Saldeen. Decreased lung hyaluronan in a model of ARDS in the rat: effect of an inhibitor of leukocyte elastase.
Upsala journal of medical sciences.
2012 Mar; 117(1):1-9. doi:
10.3109/03009734.2011.622812. [PMID: 22283425] - Tetsuro Ishii, Eiji Warabi, Toru Yanagawa. Novel roles of peroxiredoxins in inflammation, cancer and innate immunity.
Journal of clinical biochemistry and nutrition.
2012 Mar; 50(2):91-105. doi:
10.3164/jcbn.11-109. [PMID: 22448089] - Laurence Jadin, Louis H Bookbinder, Gregory I Frost. A comprehensive model of hyaluronan turnover in the mouse.
Matrix biology : journal of the International Society for Matrix Biology.
2012 Mar; 31(2):81-9. doi:
10.1016/j.matbio.2011.11.002. [PMID: 22142621] - Seetharamaiah Attili, Ralf P Richter. Combining colloidal probe atomic force and reflection interference contrast microscopy to study the compressive mechanics of hyaluronan brushes.
Langmuir : the ACS journal of surfaces and colloids.
2012 Feb; 28(6):3206-16. doi:
10.1021/la204602n. [PMID: 22216832] - Roman Fischer, David C Trudgian, Cynthia Wright, Gethin Thomas, Linda A Bradbury, Matthew A Brown, Paul Bowness, Benedikt M Kessler. Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis.
Molecular & cellular proteomics : MCP.
2012 Feb; 11(2):M111.013904. doi:
10.1074/mcp.m111.013904. [PMID: 21997733] - Yasuo Niki, Tsutomu Takeuchi. [Clinical significance of serum cartilage biomarkers in the treatment of rheumatoid arthritis with biological therapy].
Clinical calcium.
2012 Feb; 22(2):205-12. doi:
clica1202205212. [PMID: 22298074] - Kirsi Rilla, Sanna Pasonen-Seppänen, Riikka Kärnä, Hannu M Karjalainen, Kari Törrönen, Ville Koistinen, Markku I Tammi, Raija H Tammi, Terhi Teräväinen, Aki Manninen. HAS3-induced accumulation of hyaluronan in 3D MDCK cultures results in mitotic spindle misorientation and disturbed organization of epithelium.
Histochemistry and cell biology.
2012 Feb; 137(2):153-64. doi:
10.1007/s00418-011-0896-x. [PMID: 22159845] - Daliborka Dusanic, Dusan Bencina, Irena Oven, Ivanka Cizelj, Mojca Bencina, Mojca Narat. Mycoplasma synoviae induces upregulation of apoptotic genes, secretion of nitric oxide and appearance of an apoptotic phenotype in infected chicken chondrocytes.
Veterinary research.
2012 Jan; 43(?):7. doi:
10.1186/1297-9716-43-7. [PMID: 22280251] - Andria P Medina, Jialing Lin, Paul H Weigel. Hyaluronan synthase mediates dye translocation across liposomal membranes.
BMC biochemistry.
2012 Jan; 13(?):2. doi:
10.1186/1471-2091-13-2. [PMID: 22276637] - Hongbing Guan, Narendra P Singh, Udai P Singh, Prakash S Nagarkatti, Mitzi Nagarkatti. Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.
PloS one.
2012; 7(4):e35650. doi:
10.1371/journal.pone.0035650. [PMID: 22532866] - Helene C D Østerholt, Ingrid Dannevig, Myra H Wyckoff, Jie Liao, Yucel Akgul, Mrithyunjay Ramgopal, Dan S Mija, Naeun Cheong, Christopher Longoria, Mala Mahendroo, Britt Nakstad, Ola D Saugstad, Rashmin C Savani. Antioxidant protects against increases in low molecular weight hyaluronan and inflammation in asphyxiated newborn pigs resuscitated with 100\% oxygen.
PloS one.
2012; 7(6):e38839. doi:
10.1371/journal.pone.0038839. [PMID: 22701723] - Alexander Y Hui, William J McCarty, Koichi Masuda, Gary S Firestein, Robert L Sah. A systems biology approach to synovial joint lubrication in health, injury, and disease.
Wiley interdisciplinary reviews. Systems biology and medicine.
2012 Jan; 4(1):15-37. doi:
10.1002/wsbm.157. [PMID: 21826801] - Gabriele Multhoff, Jürgen Radons. Radiation, inflammation, and immune responses in cancer.
Frontiers in oncology.
2012; 2(?):58. doi:
10.3389/fonc.2012.00058. [PMID: 22675673] - Yasuo Niki, Tsutomu Takeuchi, Masanori Nakayama, Hayato Nagasawa, Takahiko Kurasawa, Harumoto Yamada, Yoshiaki Toyama, Takeshi Miyamoto. Clinical significance of cartilage biomarkers for monitoring structural joint damage in rheumatoid arthritis patients treated with anti-TNF therapy.
PloS one.
2012; 7(5):e37447. doi:
10.1371/journal.pone.0037447. [PMID: 22629396] - Greg L Harris, Michael B Creason, Greg B Brulte, Deron R Herr. In vitro and in vivo antagonism of a G protein-coupled receptor (S1P3) with a novel blocking monoclonal antibody.
PloS one.
2012; 7(4):e35129. doi:
10.1371/journal.pone.0035129. [PMID: 22496900] - Haiyan Gong, Kyousuke Kobayashi, Tatsuki Sugi, Hitoshi Takemae, Hitomi Kurokawa, Taisuke Horimoto, Hiroomi Akashi, Kentaro Kato. A novel PAN/apple domain-containing protein from Toxoplasma gondii: characterization and receptor identification.
PloS one.
2012; 7(1):e30169. doi:
10.1371/journal.pone.0030169. [PMID: 22276154] - Aditya Ambade, Pranoti Mandrekar. Oxidative stress and inflammation: essential partners in alcoholic liver disease.
International journal of hepatology.
2012; 2012(?):853175. doi:
10.1155/2012/853175. [PMID: 22500241] - Kumiko Iwata, Yukiyo Asawa, Satoru Nishizawa, Yoshiyuki Mori, Satoru Nagata, Tsuyoshi Takato, Kazuto Hoshi. The development of a serum-free medium utilizing the interaction between growth factors and biomaterials.
Biomaterials.
2012 Jan; 33(2):444-54. doi:
10.1016/j.biomaterials.2011.09.056. [PMID: 22014458] - Teresa R McCurdy, Varsha Bhakta, Louise J Eltringham-Smith, Sharon Gataiance, Alison E Fox-Robichaud, William P Sheffield. In vivo clearance of alpha-1 acid glycoprotein is influenced by the extent of its N-linked glycosylation and by its interaction with the vessel wall.
Journal of biomedicine & biotechnology.
2012; 2012(?):292730. doi:
10.1155/2012/292730. [PMID: 22545002] - Ali A Alshatwi, Tarique N Hasan, Gowhar Shafi, Naveed Ahmed Syed, Abdullah H Al-Assaf, Mohammed S Alamri, Abdrohman S Al-Khalifa. Validation of the Antiproliferative Effects of Organic Extracts from the Green Husk of Juglans regia L. on PC-3 Human Prostate Cancer Cells by Assessment of Apoptosis-Related Genes.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):103026. doi:
10.1155/2012/103026. [PMID: 22454652] - Susan Yung, Tak Mao Chan. The Role of Hyaluronan and CD44 in the Pathogenesis of Lupus Nephritis.
Autoimmune diseases.
2012; 2012(?):207190. doi:
10.1155/2012/207190. [PMID: 22900150] - Aurélie Faty, Pascal Ferré, Stéphane Commans. The acute phase protein Serum Amyloid A induces lipolysis and inflammation in human adipocytes through distinct pathways.
PloS one.
2012; 7(4):e34031. doi:
10.1371/journal.pone.0034031. [PMID: 22532826] - Daniel Hagenfeld, Beatrice Borkenhagen, Tobias Schulz, Hermann Schillers, Udo Schumacher, Peter Prehm. Hyaluronan export through plasma membranes depends on concurrent K+ efflux by K(ir) channels.
PloS one.
2012; 7(6):e39096. doi:
10.1371/journal.pone.0039096. [PMID: 22701748] - Ewa Nowakowska, Tobias Schulz, Natalia Molenda, Hermann Schillers, Peter Prehm. Recovery of ΔF508-CFTR function by analogs of hyaluronan disaccharide.
Journal of cellular biochemistry.
2012 Jan; 113(1):156-64. doi:
10.1002/jcb.23339. [PMID: 21882224] - Eray Yagmur, Alexander Koch, Michaela Haumann, Rafael Kramann, Christian Trautwein, Frank Tacke. Hyaluronan serum concentrations are elevated in critically ill patients and associated with disease severity.
Clinical biochemistry.
2012 Jan; 45(1-2):82-7. doi:
10.1016/j.clinbiochem.2011.10.016. [PMID: 22085533] - Milan Laznicek, Alice Laznickova, Dagmar Cozikova, Vladimir Velebny. Preclinical pharmacokinetics of radiolabelled hyaluronan.
Pharmacological reports : PR.
2012; 64(2):428-37. doi:
10.1016/s1734-1140(12)70784-3. [PMID: 22661195] - Simon P Hart, Adriano G Rossi, Christopher Haslett, Ian Dransfield. Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN.
PloS one.
2012; 7(3):e33142. doi:
10.1371/journal.pone.0033142. [PMID: 22427969] - Kazunori Takahashi, Hiroki Mizukami, Kosuke Kamata, Wataru Inaba, Noriaki Kato, Chihiro Hibi, Soroku Yagihashi. Amelioration of acute kidney injury in lipopolysaccharide-induced systemic inflammatory response syndrome by an aldose reductase inhibitor, fidarestat.
PloS one.
2012; 7(1):e30134. doi:
10.1371/journal.pone.0030134. [PMID: 22253906] - S A Landsverk, A G Tsai, P Cabrales, M Intaglietta. Impact of enzymatic degradation of the endothelial glycocalyx on vascular permeability in an awake hamster model.
Critical care research and practice.
2012; 2012(?):842545. doi:
10.1155/2012/842545. [PMID: 22792450] - Nidhi Sofat, Saralili Dipa Robertson, Robin Wait. Fibronectin III 13-14 domains induce joint damage via Toll-like receptor 4 activation and synergize with interleukin-1 and tumour necrosis factor.
Journal of innate immunity.
2012; 4(1):69-79. doi:
10.1159/000329632. [PMID: 21997473] - Pierre Vereecken, Frank Cornelis, Nicolas Van Baren, Valérie Vandersleyen, Jean-François Baurain. A synopsis of serum biomarkers in cutaneous melanoma patients.
Dermatology research and practice.
2012; 2012(?):260643. doi:
10.1155/2012/260643. [PMID: 22287956] - P Subramanian, M Deshpande, S Locatelli-Hoops, S Moghaddam-Taaheri, D Gutierrez, D P Fitzgerald, S Guerrier, M Rapp, V Notario, S P Becerra. Identification of pigment epithelium-derived factor protein forms with distinct activities on tumor cell lines.
Journal of biomedicine & biotechnology.
2012; 2012(?):425907. doi:
10.1155/2012/425907. [PMID: 22701303] - Maria Francisca Coutinho, Lúcia Lacerda, Sandra Alves. Glycosaminoglycan storage disorders: a review.
Biochemistry research international.
2012; 2012(?):471325. doi:
10.1155/2012/471325. [PMID: 22013531] - Abraham Cohen-Bucay, Gautham Viswanathan. Urinary markers of glomerular injury in diabetic nephropathy.
International journal of nephrology.
2012; 2012(?):146987. doi:
10.1155/2012/146987. [PMID: 22645683] - Toshiyuki Murai. The role of lipid rafts in cancer cell adhesion and migration.
International journal of cell biology.
2012; 2012(?):763283. doi:
10.1155/2012/763283. [PMID: 22253629] - Jelena Joerges, Tobias Schulz, Jeannine Wegner, Udo Schumacher, Peter Prehm. Regulation of cell volume by glycosaminoglycans.
Journal of cellular biochemistry.
2012 Jan; 113(1):340-8. doi:
10.1002/jcb.23360. [PMID: 21928313] - Mercedes Fernández-Moreno, Angel Soto-Hermida, Natividad Oreiro, Sonia Pértega, Carlos Fenández-López, Ignacio Rego-Pérez, Francisco J Blanco. Mitochondrial haplogroups define two phenotypes of osteoarthritis.
Frontiers in physiology.
2012; 3(?):129. doi:
10.3389/fphys.2012.00129. [PMID: 22593743] - Fei Ke, Praveen Kumar Yadav, Liu Zhan Ju. Herbal medicine in the treatment of ulcerative colitis.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association.
2012 Jan; 18(1):3-10. doi:
10.4103/1319-3767.91726. [PMID: 22249085] - Sadie van Esch, Raymond T Krediet, Dirk G Struijk. Prognostic factors for peritonitis outcome.
Contributions to nephrology.
2012; 178(?):264-270. doi:
10.1159/000337889. [PMID: 22652748] - Manuela G Neuman, Hemda Schmilovitz-Weiss, Nir Hilzenrat, Marc Bourliere, Patrick Marcellin, Cristhian Trepo, Tony Mazulli, George Moussa, Ankit Patel, Asad A Baig, Lawrence Cohen. Markers of inflammation and fibrosis in alcoholic hepatitis and viral hepatitis C.
International journal of hepatology.
2012; 2012(?):231210. doi:
10.1155/2012/231210. [PMID: 22530132] - Elisabetta Zinellu, Antonio Junior Lepedda, Antonio Cigliano, Salvatore Pisanu, Angelo Zinellu, Ciriaco Carru, Pietro Paolo Bacciu, Franco Piredda, Anna Guarino, Rita Spirito, Marilena Formato. Association between Human Plasma Chondroitin Sulfate Isomers and Carotid Atherosclerotic Plaques.
Biochemistry research international.
2012; 2012(?):281284. doi:
10.1155/2012/281284. [PMID: 22216412] - Girish Bommaya, Soma Meran, Aleksandra Krupa, Aled Owain Phillips, Robert Steadman. Tumour necrosis factor-stimulated gene (TSG)-6 controls epithelial-mesenchymal transition of proximal tubular epithelial cells.
The international journal of biochemistry & cell biology.
2011 Dec; 43(12):1739-46. doi:
10.1016/j.biocel.2011.08.009. [PMID: 21864707] - Omid Khalilzadeh, Sina Noshad, Armin Rashidi, Aliakbar Amirzargar. Graves' ophthalmopathy: a review of immunogenetics.
Current genomics.
2011 Dec; 12(8):564-75. doi:
10.2174/138920211798120844. [PMID: 22654556] - Changjiang Fan, Chao Zhang, Liqiong Liao, Lijian Liu. Novel hyaluronan based biodegradable hydrogel and its drug release behavior.
Journal of controlled release : official journal of the Controlled Release Society.
2011 Nov; 152 Suppl 1(?):e57-8. doi:
10.1016/j.jconrel.2011.08.120. [PMID: 22195925] - Teruyoshi Saito, Hidetada Kawana, Kazuhiko Azuma, Akihiro Toyoda, Hiroshi Fujita, Motoo Kitagawa, Kenichi Harigaya. Fragmented hyaluronan is an autocrine chemokinetic motility factor supported by the HAS2-HYAL2/CD44 system on the plasma membrane.
International journal of oncology.
2011 Nov; 39(5):1311-20. doi:
10.3892/ijo.2011.1114. [PMID: 21743962] - Laura Morra, Holger Moch. Periostin expression and epithelial-mesenchymal transition in cancer: a review and an update.
Virchows Archiv : an international journal of pathology.
2011 Nov; 459(5):465-75. doi:
10.1007/s00428-011-1151-5. [PMID: 21997759] - Sangmin Kim, Jeonghun Han, Jee Soo Kim, Jung-Han Kim, Jun-Ho Choe, Jung-Hyun Yang, Seok Jin Nam, Jeong Eon Lee. Silibinin suppresses EGFR ligand-induced CD44 expression through inhibition of EGFR activity in breast cancer cells.
Anticancer research.
2011 Nov; 31(11):3767-73. doi:
". [PMID: 22110198] - Elizabeth H Stephens, Jerome G Saltarrelli, L Scott Baggett, Indrajit Nandi, Joyce J Kuo, Alan R Davis, Elizabeth A Olmsted-Davis, Michael J Reardon, Joel D Morrisett, Kathryn Jane Grande-Allen. Differential proteoglycan and hyaluronan distribution in calcified aortic valves.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.
2011 Nov; 20(6):334-42. doi:
10.1016/j.carpath.2010.10.002. [PMID: 21185747] - Carlo C Passerotti, Miguel Srougi, Alexandre C Bomfim, Joao Roberto M Martins, Katia R M Leite, Sabrina T Dos Reis, Lucia O Sampaio, Valdemar Ortiz, Carl P Dietrich, Helena B Nader. Testing for urinary hyaluronate improves detection and grading of transitional cell carcinoma.
Urologic oncology.
2011 Nov; 29(6):710-5. doi:
10.1016/j.urolonc.2009.10.006. [PMID: 19962919] - Shubhra Dutta, Anindya Roy Chowdhury, S K Srivastava, Ilora Ghosh, Kasturi Datta. Evidence for Serpentine as a novel antioxidant by a redox sensitive HABP1 overexpressing cell line by inhibiting its nuclear translocation of NF-κB.
Free radical research.
2011 Nov; 45(11-12):1279-88. doi:
10.3109/10715762.2011.610794. [PMID: 21815883] - Hideki Hiraiwa, Tadahiro Sakai, Hirohito Mitsuyama, Takashi Hamada, Ryuichiro Yamamoto, Takaaki Omachi, Yohei Ohno, Motoshige Nakashima, Naoki Ishiguro. Inflammatory effect of advanced glycation end products on human meniscal cells from osteoarthritic knees.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2011 Nov; 60(11):1039-48. doi:
10.1007/s00011-011-0365-y. [PMID: 21842276] - Toni Segovia-Silvestre, Caroline Bonnefond, Bodil C Sondergaard, Tjorbjoern Christensen, Morten A Karsdal, Anne C Bay-Jensen. Identification of the calcitonin receptor in osteoarthritic chondrocytes.
BMC research notes.
2011 Oct; 4(?):407. doi:
10.1186/1756-0500-4-407. [PMID: 21996094] - Karen W Lu, Jesús Pérez-Gil, Mercedes Echaide, H William Taeusch. Pulmonary surfactant proteins and polymer combinations reduce surfactant inhibition by serum.
Biochimica et biophysica acta.
2011 Oct; 1808(10):2366-73. doi:
10.1016/j.bbamem.2011.06.013. [PMID: 21741354] - Tiina A Jokela, Katri M Makkonen, Sanna Oikari, Riikka Kärnä, Elina Koli, Gerald W Hart, Raija H Tammi, Carsten Carlberg, Markku I Tammi. Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.
The Journal of biological chemistry.
2011 Sep; 286(38):33632-40. doi:
10.1074/jbc.m111.265637. [PMID: 21795679] - Wendy E Heywood, Tracey E Madgett, Darrell Wang, Amanda Wallington, Julie Hogg, Kevin Mills, Neil D Avent. 2D DIGE analysis of maternal plasma for potential biomarkers of Down Syndrome.
Proteome science.
2011 Sep; 9(?):56. doi:
10.1186/1477-5956-9-56. [PMID: 21929753] - Kylie R Dunning, Lisa K Akison, Darryl L Russell, Robert J Norman, Rebecca L Robker. Increased beta-oxidation and improved oocyte developmental competence in response to l-carnitine during ovarian in vitro follicle development in mice.
Biology of reproduction.
2011 Sep; 85(3):548-55. doi:
10.1095/biolreprod.110.090415. [PMID: 21613630] - Giuseppe M Campo, Angela Avenoso, Giancarlo Nastasi, Antonio Micali, Vera Prestipino, Mario Vaccaro, Angela D'Ascola, Alberto Calatroni, Salvatore Campo. Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression.
Biochimica et biophysica acta.
2011 Sep; 1812(9):1170-81. doi:
10.1016/j.bbadis.2011.06.006. [PMID: 21723389] - Yoshiko Kashiwagi, Koichi Nishitsuka, Hiroshi Takamura, Teiko Yamamoto, Hidetoshi Yamashita. Cloning and characterization of human vitreous tissue-derived cells.
Acta ophthalmologica.
2011 Sep; 89(6):538-43. doi:
10.1111/j.1755-3768.2009.01736.x. [PMID: 19878119] - Ancha Baranova, Priyanka Lal, Aybike Birerdinc, Zobair M Younossi. Non-invasive markers for hepatic fibrosis.
BMC gastroenterology.
2011 Aug; 11(?):91. doi:
10.1186/1471-230x-11-91. [PMID: 21849046] - Deborah A Blake, Nicolai V Bovin, Dan Bess, Stephen M Henry. FSL constructs: a simple method for modifying cell/virion surfaces with a range of biological markers without affecting their viability.
Journal of visualized experiments : JoVE.
2011 Aug; ?(54):. doi:
10.3791/3289. [PMID: 21847082] - Toni Segovia-Silvestre, Vedrana Reichenbach, Guillermo Fernández-Varo, Efstathios Vassiliadis, Natasha Barascuk, Manuel Morales-Ruiz, Morten A Karsdal, Wladimiro Jiménez. Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis.
Fibrogenesis & tissue repair.
2011 Aug; 4(?):19. doi:
10.1186/1755-1536-4-19. [PMID: 21813019] - Wilmar M Wiersinga. Autoimmunity in Graves' ophthalmopathy: the result of an unfortunate marriage between TSH receptors and IGF-1 receptors?.
The Journal of clinical endocrinology and metabolism.
2011 Aug; 96(8):2386-94. doi:
10.1210/jc.2011-0307. [PMID: 21677036] - Andreas Rössler, Martin Fink, Nandu Goswami, Jerry J Batzel. Modeling of hyaluronan clearance with application to estimation of lymph flow.
Physiological measurement.
2011 Aug; 32(8):1213-38. doi:
10.1088/0967-3334/32/8/014. [PMID: 21743125] - Yvonne M Golightly, Stephen W Marshall, Virginia B Kraus, Jordan B Renner, Andrés Villaveces, Carri Casteel, Joanne M Jordan. Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms?.
Arthritis and rheumatism.
2011 Aug; 63(8):2276-83. doi:
10.1002/art.30412. [PMID: 21506100] - Benedicte Andre, Cecile Duterme, Kris Van Moer, Jeannine Mertens-Strijthagen, Michel Jadot, Bruno Flamion. Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase.
Biochemical and biophysical research communications.
2011 Jul; 411(1):175-9. doi:
10.1016/j.bbrc.2011.06.125. [PMID: 21740893] - Bodil Schmidt-Nielsen, Bent Schmidt-Nielsen. On the function of the mammalian renal papilla and the peristalsis of the surrounding pelvis.
Acta physiologica (Oxford, England).
2011 Jul; 202(3):379-85. doi:
10.1111/j.1748-1716.2011.02261.x. [PMID: 21281458] - Gyorgy Nagyeri, Marianna Radacs, Sheida Ghassemi-Nejad, Beata Tryniszewska, Katalin Olasz, Gabor Hutas, Zsuzsa Gyorfy, Vincent C Hascall, Tibor T Glant, Katalin Mikecz. TSG-6 protein, a negative regulator of inflammatory arthritis, forms a ternary complex with murine mast cell tryptases and heparin.
The Journal of biological chemistry.
2011 Jul; 286(26):23559-69. doi:
10.1074/jbc.m111.222026. [PMID: 21566135] - Min Sung Kim, Ki Ho Lee, Won Mee Lee, Jin Hyun Jun, Dong Hee Kim. CD44 disruption attenuates murine hepatic ischemia/reperfusion injury.
Journal of Korean medical science.
2011 Jul; 26(7):919-26. doi:
10.3346/jkms.2011.26.7.919. [PMID: 21738346] - Daryn R Michael, Aled O Phillips, Aleksandra Krupa, John Martin, James E Redman, Abdalsamed Altaher, Rachel D Neville, Jason Webber, Min-young Kim, Timothy Bowen. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell.
The Journal of biological chemistry.
2011 Jun; 286(22):19523-32. doi:
10.1074/jbc.m111.233916. [PMID: 21357421] - Teresa S Barata, Ian Teo, Steve Brocchini, Mire Zloh, Sunil Shaunak. Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses.
PLoS computational biology.
2011 Jun; 7(6):e1002095. doi:
10.1371/journal.pcbi.1002095. [PMID: 21738462] - Gülseren Seven, Senem Ceren Karatayli, S Kenan Köse, Mustafa Yakut, Gökhan Kabaçam, Murat Törüner, Aylin Okçu Heper, Michael Voelker, Esra Erden, A Mithat Bozdayi, Ozden Uzunalımoğlu, Hakan Bozkaya, Cihan Yurdaydin, Detlef Schuppan. Serum connective tissue markers as predictors of advanced fibrosis in patients with chronic hepatitis B and D.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology.
2011 Jun; 22(3):305-14. doi:
10.4318/tjg.2011.0217. [PMID: 21805422] - Eva Nagyova, Antonella Camaioni, Sona Scsukova, Alzbeta Mlynarcikova, Radek Prochazka, Lucie Nemcova, Antonietta Salustri. Activation of cumulus cell SMAD2/3 and epidermal growth factor receptor pathways are involved in porcine oocyte-cumulus cell expansion and steroidogenesis.
Molecular reproduction and development.
2011 Jun; 78(6):391-402. doi:
10.1002/mrd.21312. [PMID: 21520325] - Seema Kumar, Sarah Nadeem, Marius N Stan, Michael Coenen, Rebecca S Bahn. A stimulatory TSH receptor antibody enhances adipogenesis via phosphoinositide 3-kinase activation in orbital preadipocytes from patients with Graves' ophthalmopathy.
Journal of molecular endocrinology.
2011 Jun; 46(3):155-63. doi:
10.1530/jme-11-0006. [PMID: 21321093] - Wang Kai-Feng, Pan Hong-Ming, Lou Hai-Zhou, Shen Li-Rong, Zhu Xi-Yan. Interleukin-11-induced capillary leak syndrome in primary hepatic carcinoma patients with thrombocytopenia.
BMC cancer.
2011 May; 11(?):204. doi:
10.1186/1471-2407-11-204. [PMID: 21619578] - Aimin Wang, Carol de la Motte, Mark Lauer, Vincent Hascall. Hyaluronan matrices in pathobiological processes.
The FEBS journal.
2011 May; 278(9):1412-8. doi:
10.1111/j.1742-4658.2011.08069.x. [PMID: 21362136]