Sodium picosulfate monohydrate (BioDeep_00000701904)
代谢物信息卡片
Sodium picosulfate monohydrate
化学式: C18H15NNa2O9S2 (498.998362)
中文名称: 匹可硫酸钠一水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=NC(=C1)C(C2=CC=C(C=C2)OS(=O)(=O)[O-])C3=CC=C(C=C3)OS(=O)(=O)[O-].O.[Na+].[Na+]
InChI: /p-2
描述信息
C78276 - Agent Affecting Digestive System or Metabolism > C29697 - Laxative
D005765 - Gastrointestinal Agents > D002400 - Cathartics
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Renáta Bor, Mária Matuz, Anna Fabián, Zoltán Szepes, Kata Szántó, Klaudia Farkas, Mariann Rutka, Ágnes Milassin, Daniella Pigniczki, Anita Bálint, Tibor Tóth, Tamás Molnár. Efficacy, tolerability and safety of a split-dose bowel cleansing regimen of magnesium citrate with sodium picosulfate - a phase IV clinical observational study.
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.
2021 Sep; 113(9):635-642. doi:
10.17235/reed.2020.7073/2020. [PMID: 33371690] - Elisabeth M H Mathus-Vliegen, Karin van der Vliet, Inge J Wignand-van der Storm, John S Stadwijk. Efficacy and Safety of Sodium Picosulfate/Magnesium Citrate for Bowel Preparation in a Physically Disabled Outpatient Population: A Randomized, Endoscopist-Blinded Comparison With Ascorbic Acid-Enriched Polyethylene Glycol Solution Plus Bisacodyl (The PICO-MOVI Study).
Diseases of the colon and rectum.
2018 Feb; 61(2):239-249. doi:
10.1097/dcr.0000000000000956. [PMID: 29337780] - G S Labuschagne, R W Morris. The effect of oral intake during the immediate pre-colonoscopy time period on volume depletion in patients who receive sodium picosulfate.
Anaesthesia and intensive care.
2017 07; 45(4):485-489. doi:
10.1177/0310057x1704500412. [PMID: 28673219] - Matthew A Weir, Jamie L Fleet, Chris Vinden, Salimah Z Shariff, Kuan Liu, Haoyuan Song, Arsh K Jain, Sonja Gandhi, William F Clark, Amit X Garg. Hyponatremia and sodium picosulfate bowel preparations in older adults.
The American journal of gastroenterology.
2014 May; 109(5):686-94. doi:
10.1038/ajg.2014.20. [PMID: 24589671] - A Ghanouni, S G Smith, S Halligan, S A Taylor, A Plumb, D Boone, C von Wagner. An interview study analysing patients' experiences and perceptions of non-laxative or full-laxative preparation with faecal tagging prior to CT colonography.
Clinical radiology.
2013 May; 68(5):472-8. doi:
10.1016/j.crad.2012.10.012. [PMID: 23265916] - Yong Yang, Jinghua Yu, Youming Lu, Yu Xia, Dafang Zhong, Xiaoyan Chen. High-sensitivity liquid chromatography-tandem mass spectrometry method for the simultaneous determination of sodium picosulfate and its three major metabolites in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2013 Feb; 915-916(?):1-7. doi:
10.1016/j.jchromb.2012.12.007. [PMID: 23314398] - Toru Sugihara, Hideo Yasunaga, Hiromasa Horiguchi, Tetsuya Fujimura, Hiroaki Nishimatsu, Kazuhiko Ohe, Shinya Matsuda, Kiyohide Fushimi, Michael W Kattan, Yukio Homma. Does mechanical bowel preparation improve quality of laparoscopic nephrectomy? Propensity score-matched analysis in Japanese series.
Urology.
2013 Jan; 81(1):74-9. doi:
10.1016/j.urology.2012.09.032. [PMID: 23273073] - Adam Rahman, Stephen J Vanner, Adrian Baranchuk, Lawrence C Hookey. Serial monitoring of the physiological effects of the standard Pico-Salax® regimen for colon cleansing in healthy volunteers.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie.
2012 Jul; 26(7):424-8. doi:
10.1155/2012/757583. [PMID: 22803016] - P K Flanagan, M S Ahmed, S M Tin, S Sarkar. Service implications of implementing guidance for oral bowel cleansing agents in colonoscopy.
The journal of the Royal College of Physicians of Edinburgh.
2011 Jun; 41(2):100-5. doi:
10.4997/jrcpe.2011.202. [PMID: 21677910] - Christian Friedrich, Erika Richter, Dirk Trommeshauser, Sandra de Kruif, Thijs van Iersel, Ken Mandel, Ulrika Gessner. Absence of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel-group, multiple-dose study in healthy lactating women.
Drug metabolism and pharmacokinetics.
2011; 26(5):458-64. doi:
10.2133/dmpk.dmpk-11-rg-007. [PMID: 21697613] - D Turner, E I Benchimol, H Dunn, A M Griffiths, K Frost, V Scaini, J Avolio, S C Ling. Pico-Salax versus polyethylene glycol for bowel cleanout before colonoscopy in children: a randomized controlled trial.
Endoscopy.
2009 Dec; 41(12):1038-45. doi:
10.1055/s-0029-1215333. [PMID: 19967619] - M D Evans, K Barton, G A Pritchard, E J Williams, S S Karandikar. Plasma magnesium should be monitored perioperatively in patients undergoing colorectal resection.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.
2009 Jul; 11(6):613-8. doi:
10.1111/j.1463-1318.2008.01612.x. [PMID: 18624818] - Paulo Miki, Carlos Renato dos Reis Lemos, Pedro Popoutchi, Ricardo Luiz dos Santos Garcia, José Joaquim Ribeiro da Rocha, Omar Feres. Comparison of colon-cleansing methods in preparation for colonoscopy--comparative efficacy of solutions of mannitol, sodium picosulfate and monobasic and dibasic sodium phosphates.
Acta cirurgica brasileira.
2008; 23 Suppl 1(?):108-11; discussion 111. doi:
10.1590/s0102-86502008000700018. [PMID: 18516457] - Ju-Xiu He, Emi Goto, Teruaki Akao, Tadato Tani. Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2007 Aug; 14(7-8):452-9. doi:
10.1016/j.phymed.2006.09.014. [PMID: 17097282] - G Sanders, C H C Arthur, K B Hosie, A W Lambert. Is patient outcome affected by the administration of intravenous fluid during bowel preparation for colonic surgery?.
Annals of the Royal College of Surgeons of England.
2007 Jul; 89(5):487-9. doi:
10.1308/003588407x202047. [PMID: 17688720] - R Wulkow, J-M Vix, C Schuijt, H Peil, M A Kamm, C Jordan. Randomised, placebo-controlled, double-blind study to investigate the efficacy and safety of the acute use of sodium picosulphate in patients with chronic constipation.
International journal of clinical practice.
2007 Jun; 61(6):944-50. doi:
10.1111/j.1742-1241.2007.01374.x. [PMID: 17504357] - Emi Goto, Ju-Xiu He, Teruaki Akao, Tadato Tani. Bioavailability of glycyrrhizin from Shaoyao-Gancao-Tang in laxative-treated rats.
The Journal of pharmacy and pharmacology.
2005 Oct; 57(10):1359-63. doi:
10.1211/jpp.57.10.0016. [PMID: 16259766] - Fran Ryan, Tina Anobile, Diane Scutt, Marion Hopwood, Gerry Murphy. Effects of oral sodium picosulphate Picolax on urea and electrolytes.
Nursing standard (Royal College of Nursing (Great Britain) : 1987).
2005 Jul; 19(45):41-5. doi:
10.7748/ns2005.07.19.45.41.c3912. [PMID: 16050231] - Jochen Beyer, Frank T Peters, Hans H Maurer. Screening procedure for detection of stimulant laxatives and/or their metabolites in human urine using gas chromatography-mass spectrometry after enzymatic cleavage of conjugates and extractive methylation.
Therapeutic drug monitoring.
2005 Apr; 27(2):151-7. doi:
10.1097/01.ftd.0000150878.36296.04. [PMID: 15795644] - G M Forbes, J T Edwards, N M Foster, C J Wood, R M Mendelson. Randomized single blind trial of two low-volume bowel preparations for screening computed tomographic colonography.
Abdominal imaging.
2005 Jan; 30(1):48-52. doi:
10.1007/s00261-004-0226-z. [PMID: 15647870] - G Sanders, S J Mercer, K Saeb-Parsey, M A Akhavani, K B Hosie, A W Lambert. Randomized clinical trial of intravenous fluid replacement during bowel preparation for surgery.
The British journal of surgery.
2001 Oct; 88(10):1363-5. doi:
10.1046/j.0007-1323.2001.01872.x. [PMID: 11578293] - H Ito, T Kiso, H Yuki, Y Naitoh, K Miyata, K Iwaoka, T Yamaguchi. Investigation of the effects of YM-31636, a novel 5-HT3 receptor agonist, on defecation in normal and constipated ferrets.
European journal of pharmacology.
2001 Jul; 424(2):151-7. doi:
10.1016/s0014-2999(01)01147-5. [PMID: 11476761] - K Subramonian, J McNaught, N Spencer, S C Harrison. Is bowel preparation useful before radiography of the renal tract in patients with spinal cord injury?.
BJU international.
2000 Feb; 85(3):224-6. doi:
10.1046/j.1464-410x.2000.00440.x. [PMID: 10671872] - A I Parfenov, N I Poleva. [Laxigal effectiveness in constipation of various etiology].
Klinicheskaia meditsina.
2000; 78(12):49-50. doi:
NULL. [PMID: 11210355] - A J Macleod, K A Duncan, R H Pearson, R R Bleakney. A comparison of Fleet Phospho-soda with Picolax in the preparation of the colon for double contrast barium enema.
Clinical radiology.
1998 Aug; 53(8):612-4. doi:
10.1016/s0009-9260(98)80156-6. [PMID: 9744590] - D Hamilton, D Mulcahy, D Walsh, C Farrelly, W P Tormey, G Watson. Sodium picosulphate compared with polyethylene glycol solution for large bowel lavage: a prospective randomised trial.
The British journal of clinical practice.
1996 Mar; 50(2):73-5. doi:
NULL. [PMID: 8731641] - M J Swarbrick, M C Collins, D J Moore, K D McBride. A comparative trial of magnesium citrate (Citramag) and Picolax for barium enema bowel preparation.
Clinical radiology.
1994 Jun; 49(6):379-81. doi:
10.1016/s0009-9260(05)81821-5. [PMID: 8045060] - C D George, S J Vinnicombe, A R Balkissoon, C W Heron. Bowel preparation before intravenous urography: is it necessary?.
The British journal of radiology.
1993 Jan; 66(781):17-9. doi:
10.1259/0007-1285-66-781-17. [PMID: 8428245] - M Dakkak, K Aziz, J R Bennett. Short report: comparison of two orally administered bowel preparations for colonoscopy--polyethylene glycol and sodium picosulphate.
Alimentary pharmacology & therapeutics.
1992 Aug; 6(4):513-9. doi:
10.1111/j.1365-2036.1992.tb00566.x. [PMID: 1420744] - D H Kim, S H Hyun, S B Shim, K Kobashi. The role of intestinal bacteria in the transformation of sodium picosulfate.
Japanese journal of pharmacology.
1992 May; 59(1):1-5. doi:
10.1254/jjp.59.1. [PMID: 1507649] - Y Araki, H Isomoto, K Shirouzu, T Morodomi, T Kakegawa. A study on polyethylene glycol electrolyte lavage solution and sodium picosulfate combined pretreatment method for colonoscopy.
The Kurume medical journal.
1992; 39(2):117-21. doi:
10.2739/kurumemedj.39.117. [PMID: 1405431] - H Takada, N S Ambrose, K Galbraith, J Alexander-Williams, M R Keighley. Quantitative appraisal of Picolax (sodium picosulfate/magnesium citrate) in the preparation of the large bowel for elective surgery.
Diseases of the colon and rectum.
1990 Aug; 33(8):679-83. doi:
10.1007/bf02150744. [PMID: 2376224] - NULL. Faecal peritonitis induced by Picolax.
British medical journal (Clinical research ed.).
1987 Nov; 295(6610):1413-4. doi:
10.1136/bmj.295.6610.1413-a. [PMID: 3121034] - R F Phipps, S Fraser. Faecal peritonitis induced by picolax.
British medical journal (Clinical research ed.).
1987 Oct; 295(6605):1027. doi:
10.1136/bmj.295.6605.1027. [PMID: 3120859] - K Hughes, S Mann, M B Cooke, W B James. A new oral bowel evacuant (Picolax) for colon cleansing.
Clinical radiology.
1983 Jan; 34(1):75-7. doi:
10.1016/s0009-9260(83)80387-0. [PMID: 6822041] - R B Sund, K Songedal, T Harestad, B Salvesen, S Kristiansen. Enterohepatic circulation, urinary excretion and laxative action of some bisacodyl derivatives after intragastric administration in the rat.
Acta pharmacologica et toxicologica.
1981 Jan; 48(1):73-80. doi:
10.1111/j.1600-0773.1981.tb01591.x. [PMID: 7223440]