2-(2-Benzofuranyl)-2-imidazoline (BioDeep_00000700505)
代谢物信息卡片
化学式: C11H10N2O (186.079309)
中文名称: 2-(2-苯并呋喃)-2-咪唑啉
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CN=C(N1)C2=CC3=CC=CC=C3O2
InChI: InChI=1S/C11H10N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,7H,5-6H2,(H,12,13)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D000345 - Affinity Labels
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Yirui Huang, Meijuan Xiao, Zusen Ye, Zhao Han, P S Reinach, Jianhua Cheng. 2-(-2-Benzofuranyl)-2-imidazoline reciprocally regulates Th17/Treg balance induced by ischemic stroke in rats.
Die Pharmazie.
2020 11; 75(11):586-589. doi:
10.1691/ph.2020.0634. [PMID: 33239134] - Sònia Abás, Sergio Rodríguez-Arévalo, Andrea Bagán, Christian Griñán-Ferré, Foteini Vasilopoulou, Iria Brocos-Mosquera, Carolina Muguruza, Belén Pérez, Elies Molins, F Javier Luque, Pilar Pérez-Lozano, Steven de Jonghe, Dirk Daelemans, Lieve Naesens, José Brea, M Isabel Loza, Elena Hernández-Hernández, Jesús A García-Sevilla, M Julia García-Fuster, Milica Radan, Teodora Djikic, Katarina Nikolic, Mercè Pallàs, Luis F Callado, Carmen Escolano. Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease.
Journal of medicinal chemistry.
2020 04; 63(7):3610-3633. doi:
10.1021/acs.jmedchem.9b02080. [PMID: 32150414] - Jisha Tian, Rui Chen, Lan Hu, Linglei Zhang, Jiaou Chen, Yungang Cao, Xiaoling Guo, Longqing Wang, Zhao Han. The protective effect of 2-(2-benzonfu-ranyl)-2-imidazoline against oxygen-glucose deprivation in cultured rat cortical astrocytes.
Neuroscience research.
2018 Aug; 133(?):1-6. doi:
10.1016/j.neures.2017.10.010. [PMID: 29107612] - Neil J Anderson, Isabelle Seif, David J Nutt, Alan L Hudson, Emma S J Robinson. Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice.
Journal of neurochemistry.
2006 Mar; 96(6):1551-9. doi:
10.1111/j.1471-4159.2006.03662.x. [PMID: 16476082] - Frédérique Touzeau, Axelle Arrault, Gérald Guillaumet, Elizabeth Scalbert, Bruno Pfeiffer, Marie-Claire Rettori, Pierre Renard, Jean-Yves Mérour. Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.
Journal of medicinal chemistry.
2003 May; 46(10):1962-79. doi:
10.1021/jm021050c. [PMID: 12723959] - P A Coates, P Grundt, E S Robinson, D J Nutt, R Tyacke, A L Hudson, J W Lewis, S M Husbands. Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand.
Bioorganic & medicinal chemistry letters.
2000 Mar; 10(6):605-7. doi:
10.1016/s0960-894x(00)00062-7. [PMID: 10741563] - P R King, A L Gundlach, W J Louis. Identification of imidazoline-receptor binding sites in cortex and medulla of the bovine adrenal gland. Colocalization with MAO-A and MAO-B.
Annals of the New York Academy of Sciences.
1999 Jun; 881(?):161-70. doi:
10.1111/j.1749-6632.1999.tb09355.x. [PMID: 10415911] - P R King, S Suzuki, A R Hosseini, D Iakovidis, T L Nero, G P Jackman, W J Louis, A L Gundlach. [3H]Rilmenidine-labelled imidazoline-receptor binding sites co-localize with [3H]2-(benzofuranyl)-2-imidazoline-labelled imidazoline-receptor binding sites and monoamine oxidase-B in rabbit, but not rat, kidney.
Journal of the autonomic nervous system.
1998 Oct; 72(2-3):118-28. doi:
10.1016/s0165-1838(98)00096-4. [PMID: 9851560]